$191 Find Cheap Flights from Roanoke to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$224
Myrtle Beach
Myrtle Beach1 stop$357
Charlotte
Charlottenonstop$379
Charleston
Charleston1 stop$224
Myrtle Beach
Myrtle Beach1 stop$357
Charlotte
Charlottenonstop$379

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Mon, Aug 24 - Thu, Aug 27
Multiple Airlines Logo
2:36 pm - 8:38 am
ROA
-
CHS
18h 02m
1 stop
Multiple Airlines Logo
2:53 pm - 2:05 pm
CHS
-
ROA
23h 12m
1 stop
$224Multiple Airlines
Tue, Sep 15 - Wed, Sep 30
Delta Logo
6:40 pm - 11:57 pm
ROA
-
CHS
5h 17m
1 stop
Delta Logo
6:40 am - 10:31 am
CHS
-
ROA
3h 51m
1 stop
$261Delta
Fri, Sep 18 - Tue, Sep 29
Delta Logo
6:40 pm - 10:09 pm
ROA
-
CHS
3h 29m
1 stop
Delta Logo
11:11 am - 2:50 pm
CHS
-
ROA
3h 39m
1 stop
$275Delta
Thu, Jul 23 - Sun, Jul 26
Delta Logo
7:57 pm - 12:26 am
ROA
-
CHS
4h 29m
1 stop
Delta Logo
7:59 pm - 12:25 am
CHS
-
ROA
4h 26m
1 stop
$289Delta
Thu, Sep 17 - Tue, Sep 29
Delta Logo
6:00 am - 10:06 am
ROA
-
CHS
4h 06m
1 stop
Delta Logo
5:33 pm - 11:59 pm
CHS
-
ROA
6h 26m
1 stop
$290Delta
Mon, Aug 24 - Thu, Aug 27
Multiple Airlines Logo
2:36 pm - 8:38 am
ROA
-
CHS
18h 02m
1 stop
Multiple Airlines Logo
4:51 pm - 2:05 pm
CHS
-
ROA
21h 14m
2 stops
$293Multiple Airlines
Fri, Sep 4 - Sat, Sep 5
American Airlines Logo
6:15 am - 9:39 am
ROA
-
CHS
3h 24m
1 stop
American Airlines Logo
9:13 am - 12:35 pm
CHS
-
ROA
3h 22m
1 stop
$310American Airlines
Sat, Aug 8 - Sat, Aug 15
American Airlines Logo
6:15 am - 7:46 am
ROA
-
CLT
1h 31mnonstop
American Airlines Logo
6:00 pm - 7:21 pm
CLT
-
ROA
1h 21mnonstop
$379American Airlines
Thu, Jul 16 - Mon, Jul 20
United Airlines Logo
6:40 am - 2:19 pm
ROA
-
MYR
7h 39m
1 stop
United Airlines Logo
3:15 pm - 9:03 pm
MYR
-
ROA
5h 48m
1 stop
$399United Airlines
Sat, Aug 8 - Sat, Aug 15
United Airlines Logo
10:30 am - 2:11 pm
ROA
-
CLT
3h 41m
1 stop
United Airlines Logo
7:55 pm - 11:44 pm
CLT
-
ROA
3h 49m
1 stop
$399United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Roanoke to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Roanoke to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Roanoke to South Carolina is January, when tickets cost $144 (return) on average. On the other hand, the most expensive months are December and March, when the average cost of round-trip tickets is $368 and $336 respectively.

Good to know

Low seasonJanuary
Cheapest flight$191
Best time to beat the crowds with an average 54% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Roanoke to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $323 one-way - $400 round-trip

Reviews of the top airlines flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8453 reviews
7.8Entertainment
7.2Food
7.8Comfort
8.1Boarding
8.5Crew
Airline reviews

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

6.0 GoodSarah, Jun 2026
LGA - MYR
Read more Delta reviews

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

Flight attendants were great. Cheerful, upbeat and friendly. Jet, in particular, was fantastic.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

Would have been better if there was a nonstop flight from Tampa to Norfolk or Tampa to New Port News.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

They did not offer coffee on a 7am flight…awful!!

Excellent service. Flight attendance like Jessica,, on our flight, is a reason I wouldn’t mind flying through British Airways again. Jessica,, was very courteous and helpful.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

Pros: "Nothing"
Cons: "Getting all my luggage. Allowing my wife and I to sit together"

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports