$180 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$214
Myrtle Beach
Myrtle Beach1 stop$219
Charlotte
Charlottenonstop$283
Charleston
Charleston1 stop$214
Myrtle Beach
Myrtle Beach1 stop$219
Charlotte
Charlottenonstop$283

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Wed, Feb 18 - Sat, Feb 21
Delta Logo
11:21 am - 5:55 pmROA-CHS
6h 34m1 stop
Delta Logo
8:30 am - 2:09 pmCHS-ROA
5h 39m1 stop
$214Delta
Find Deal
Sat, Dec 6 - Sat, Dec 13
Delta Logo
6:00 am - 9:35 amROA-MYR
3h 35m1 stop
Delta Logo
6:00 am - 10:40 amMYR-ROA
4h 40m1 stop
$219Delta
Find Deal
Wed, Feb 18 - Sat, Feb 21
Delta Logo
11:21 am - 5:55 pmROA-CHS
6h 34m1 stop
Delta Logo
12:52 pm - 7:18 pmCHS-ROA
6h 26m1 stop
$229Delta
Find Deal
Wed, Feb 18 - Sat, Feb 21
Delta Logo
11:21 am - 5:55 pmROA-CHS
6h 34m1 stop
Delta Logo
12:52 pm - 7:18 pmCHS-ROA
6h 26m1 stop
$244Delta
Find Deal
Mon, Dec 1 - Wed, Dec 10
American Airlines Logo
8:56 am - 3:12 pmROA-CHS
6h 16m1 stop
American Airlines Logo
6:10 am - 9:44 amCHS-ROA
3h 34m1 stop
$264American Airlines
Find Deal
Sat, Dec 13 - Sat, Dec 20
American Airlines Logo
8:10 pm - 9:43 pmROA-CLT
1h 33mnonstop
American Airlines Logo
10:25 pm - 11:39 pmCLT-ROA
1h 14mnonstop
$283American Airlines
Find Deal
Sat, Nov 15 - Wed, Nov 19
American Airlines Logo
2:32 pm - 10:05 pmROA-MYR
7h 33m2 stops
American Airlines Logo
3:32 pm - 6:47 pmMYR-ROA
3h 15m1 stop
$284American Airlines
Find Deal
Sat, Dec 6 - Sat, Dec 13
American Airlines Logo
8:12 am - 1:59 pmROA-MYR
5h 47m2 stops
American Airlines Logo
6:08 pm - 12:03 amMYR-ROA
5h 55m1 stop
$288American Airlines
Find Deal
Mon, Dec 1 - Fri, Dec 5
United Airlines Logo
6:20 am - 10:08 amROA-CHS
3h 48m1 stop
United Airlines Logo
7:47 pm - 6:56 pmCHS-ROA
23h 09m1 stop
$398United Airlines
Find Deal
Mon, Dec 1 - Mon, Dec 8
United Airlines Logo
7:50 pm - 12:35 pmROA-MYR
16h 45m2 stops
United Airlines Logo
1:16 pm - 8:45 pmMYR-ROA
31h 29m2 stops
$691United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Roanoke to South Carolina?

The average price of all round-trip flights from Roanoke to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Roanoke to South Carolina, you should consider leaving on a Saturday and avoid Mondays if you are looking for the best rates. For your return to Roanoke, you’ll find the best rates on Saturdays and the most expensive ones on Mondays.

Find deals

Good to know

Low seasonJuly
Cheapest flight$180
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $260 on average. Morning departures are around 11% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $373.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $289 one-way - $366 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11049 reviews
7.2Comfort
8.0Crew
6.4Food
6.9Entertainment
7.5Boarding
Airline reviews

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

10.0 ExcellentAnonymous, Nov 2025MIA - LAX
Read more American Airlines reviews

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

We loved the steward on the plane. He made the night enjoyable

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports

Roanoke (ROA)