$220 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
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Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$239
Charlotte
Charlottenonstop$339
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$239
Charlotte
Charlottenonstop$339

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Tue, May 12 - Mon, May 18
Delta Logo
6:00 am - 12:19 pm
ROA
-
MYR
6h 19m
1 stop
Delta Logo
7:50 pm - 11:49 pm
MYR
-
ROA
3h 59m
1 stop
$239Delta
Fri, Jan 30 - Tue, Feb 3
American Airlines Logo
3:30 pm - 8:54 pm
ROA
-
MYR
5h 24m
1 stop
American Airlines Logo
12:05 pm - 3:05 pm
MYR
-
ROA
3h 00m
1 stop
$249American Airlines
Mon, Jun 1 - Mon, Jun 8
Delta Logo
7:50 pm - 11:56 pm
ROA
-
CHS
4h 06m
1 stop
Delta Logo
5:55 pm - 11:49 pm
CHS
-
ROA
5h 54m
1 stop
$249Delta
Fri, Jan 30 - Tue, Feb 3
American Airlines Logo
3:30 pm - 8:54 pm
ROA
-
MYR
5h 24m
1 stop
American Airlines Logo
8:00 am - 4:10 pm
MYR
-
ROA
8h 10m
2 stops
$254American Airlines
Sat, Jan 31 - Wed, Feb 4
Delta Logo
3:47 pm - 8:55 pm
ROA
-
CHS
5h 08m
1 stop
Delta Logo
5:25 am - 10:39 am
CHS
-
ROA
5h 14m
1 stop
$259Delta
Wed, May 13 - Wed, May 20
Delta Logo
6:00 am - 12:19 pm
ROA
-
MYR
6h 19m
1 stop
Delta Logo
7:50 pm - 11:49 pm
MYR
-
ROA
3h 59m
1 stop
$264Delta
Sat, May 30 - Thu, Jun 4
Delta Logo
6:00 am - 10:09 am
ROA
-
MYR
4h 09m
1 stop
Delta Logo
7:50 pm - 11:49 pm
MYR
-
ROA
3h 59m
1 stop
$279Delta
Mon, May 11 - Tue, May 19
American Airlines Logo
8:00 pm - 11:57 pm
ROA
-
MYR
3h 57m
1 stop
American Airlines Logo
6:04 am - 9:46 am
MYR
-
ROA
3h 42m
1 stop
$299American Airlines
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
10:15 am - 2:48 pm
ROA
-
CHS
4h 33m
1 stop
United Airlines Logo
2:58 pm - 7:31 pm
CHS
-
ROA
4h 33m
1 stop
$319United Airlines
Sun, Feb 15 - Fri, Feb 20
United Airlines Logo
10:15 am - 2:49 pm
ROA
-
CHS
4h 34m
1 stop
United Airlines Logo
7:47 pm - 8:07 pm
CHS
-
ROA
24h 20m
1 stop
$393United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South Carolina were found on Delta ($239) and American Airlines ($249).

Find deals

Good to know

Low seasonApril
Cheapest flight$220
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $218 one-way - $336 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11153 reviews
7.2Comfort
7.5Boarding
6.9Entertainment
6.4Food
8.0Crew
Airline reviews

The seat cushions were very worn so they were extremely uncomfortable.

4.0 OkayLouesa, Jan 2026
DFW - PHL
Read more American Airlines reviews

The seat cushions were very worn so they were extremely uncomfortable.

Delayed, no updates, had a rewards number but was not working

The seats from lax to DFW was so tight that I could not move my legs . No WiFi and had to pay . Not a good selection of entertainment

AA should improve their in air internet & entertainment options. Seems unreasonable to charge $20/hr and should have some form of free connections. The entertainment options are also pretty limited, movies are outdated and the series only show 3-5 episodes.

We were upgraded to First Class and it was a great flight

Amazing I love American. I’ll never fly anyone else if I can help it.

I love American. I’ll never fly anyone else if I can help it.

Flight delay and multiple gate changes including a change near boarding time to another terminal, which in DFW is a pain. Pre-boarding delay and also a further delay on the ground after boarding. About an hour and a half total delay.

On the plus side, crew was attentive, drinks were cold, and in-flight entertainment selection was better than some other airlines. On the negative aide, Plane was delayed almost an hour, either no announcements from the gate crew. Biscoff cookies are gross, appreciate airlines that give a choice. Also, crew had no personality or enthusiasm at all.

Little warm on the plane and delayed for an hour

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports

Roanoke (ROA)