$180 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$229
Myrtle Beach
Myrtle Beach1 stop$219
Charlotte
Charlottenonstop$303
Charleston
Charleston1 stop$229
Myrtle Beach
Myrtle Beach1 stop$219
Charlotte
Charlottenonstop$303

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Sat, Dec 13 - Tue, Dec 16
Delta Logo
8:00 pm - 11:43 pmROA-MYR
3h 43m1 stop
Delta Logo
6:56 pm - 12:11 amMYR-ROA
5h 15m1 stop
$219Delta
Find Deal
Sat, Dec 13 - Wed, Dec 17
American Airlines Logo
8:12 am - 1:59 pmROA-MYR
5h 47m2 stops
American Airlines Logo
3:29 pm - 9:37 pmMYR-ROA
6h 08m1 stop
$224American Airlines
Find Deal
Tue, Feb 10 - Sat, Feb 14
Delta Logo
3:49 pm - 8:55 pmROA-CHS
5h 06m1 stop
Delta Logo
1:04 pm - 7:17 pmCHS-ROA
6h 13m1 stop
$229Delta
Find Deal
Thu, Dec 11 - Wed, Dec 17
Delta Logo
6:00 am - 9:47 amROA-MYR
3h 47m1 stop
Delta Logo
6:56 pm - 12:11 amMYR-ROA
5h 15m1 stop
$234Delta
Find Deal
Sat, Dec 13 - Mon, Dec 15
American Airlines Logo
8:12 am - 1:59 pmROA-MYR
5h 47m2 stops
American Airlines Logo
4:05 pm - 8:30 pmMYR-ROA
4h 25m1 stop
$239American Airlines
Find Deal
Sat, Dec 13 - Thu, Dec 18
Delta Logo
8:00 pm - 11:43 pmROA-MYR
3h 43m1 stop
Delta Logo
6:56 pm - 12:11 amMYR-ROA
5h 15m1 stop
$254Delta
Find Deal
Mon, Dec 1 - Sun, Dec 7
Delta Logo
7:59 pm - 11:44 pmROA-MYR
3h 45m1 stop
Delta Logo
6:56 pm - 12:11 amMYR-ROA
5h 15m1 stop
$259Delta
Find Deal
Sat, Nov 29 - Wed, Dec 10
Delta Logo
6:00 am - 9:50 amROA-MYR
3h 50m1 stop
Delta Logo
6:56 pm - 12:11 amMYR-ROA
5h 15m1 stop
$269Delta
Find Deal
Sat, Dec 13 - Tue, Dec 16
American Airlines Logo
8:12 am - 1:59 pmROA-MYR
5h 47m2 stops
American Airlines Logo
6:23 am - 12:17 pmMYR-ROA
5h 54m1 stop
$284American Airlines
Find Deal
Fri, Jan 9 - Sun, Jan 11
Multiple Airlines Logo
3:53 pm - 10:58 amROA-CLT
19h 05m3 stops
Multiple Airlines Logo
9:07 pm - 3:03 pmCLT-ROA
17h 56m2 stops
$386Multiple Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Roanoke to South Carolina?

The average price of all round-trip flights from Roanoke to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Roanoke to South Carolina, you should consider leaving on a Saturday and avoid Mondays if you are looking for the best rates. For your return to Roanoke, you’ll find the best rates on Saturdays and the most expensive ones on Mondays.

Good to know

Low seasonJuly
Cheapest flight$180
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 13% increase in price.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $260 on average. Morning departures are around 11% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $373.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $289 one-way - $366 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11042 reviews
6.4Food
7.2Comfort
7.5Boarding
8.0Crew
6.9Entertainment
Airline reviews

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

6.0 GoodDonald, Nov 2025DFW - MSY
Read more American Airlines reviews

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

We were told the flight was delayed 5 times, then it was moved to the next day.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports