$194 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
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Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$229
Myrtle Beach
Myrtle Beach1 stop$307
Charlotte
Charlottenonstop$303
Charleston
Charleston1 stop$229
Myrtle Beach
Myrtle Beach1 stop$307
Charlotte
Charlottenonstop$303

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Fri, Oct 31 - Mon, Nov 3
American Airlines Logo
10:09 am - 2:42 pmROA-CHS
4h 33m1 stop
American Airlines Logo
12:17 pm - 4:48 pmCHS-ROA
4h 31m1 stop
$229American Airlines
Find Deal
Fri, Sep 5 - Mon, Sep 8
American Airlines Logo
5:00 am - 10:24 amROA-CHS
5h 24m1 stop
American Airlines Logo
11:28 am - 5:50 pmCHS-ROA
6h 22m1 stop
$234American Airlines
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Tue, Sep 2 - Sat, Sep 6
Delta Logo
7:51 pm - 11:51 pmROA-CHS
4h 00m1 stop
Delta Logo
6:20 am - 10:30 amCHS-ROA
4h 10m1 stop
$239Delta
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Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
3:14 pm - 11:03 pmROA-CHS
7h 49m2 stops
American Airlines Logo
2:59 pm - 7:43 pmCHS-ROA
4h 44m1 stop
$244American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
3:14 pm - 11:03 pmROA-CHS
7h 49m2 stops
American Airlines Logo
8:12 am - 2:36 pmCHS-ROA
6h 24m2 stops
$249American Airlines
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Mon, Sep 15 - Wed, Sep 17
 Logo
6:33 pm - 12:53 pmROA-CLT
18h 20m1 stop
 Logo
2:47 pm - 8:34 pmCLT-ROA
29h 47m2 stops
Tue, Sep 9 - Wed, Sep 17
Delta Logo
6:00 am - 10:09 amROA-MYR
4h 09m1 stop
Delta Logo
6:55 pm - 12:25 amMYR-ROA
5h 30m1 stop
$307Delta
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Tue, Sep 30 - Tue, Oct 7
United Airlines Logo
10:52 am - 5:05 pmROA-CLT
6h 13m1 stop
United Airlines Logo
7:46 pm - 11:24 pmCLT-ROA
3h 38m1 stop
$363United Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
United Airlines Logo
6:45 am - 2:42 pmROA-MYR
7h 57m1 stop
United Airlines Logo
2:47 pm - 6:44 pmMYR-ROA
3h 57m1 stop
$372United Airlines
Find Deal
Thu, Oct 2 - Sun, Oct 5
 Logo
9:20 pm - 10:59 pmROA-CLT
25h 39m3 stops
 Logo
9:46 pm - 8:22 pmCLT-ROA
22h 36m3 stops
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Roanoke to South Carolina?

The average price of all round-trip flights from Roanoke to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Roanoke to South Carolina, you should consider leaving on a Saturday and avoid Mondays if you are looking for the best rates. For your return to Roanoke, you’ll find the best rates on Saturdays and the most expensive ones on Mondays.

Good to know

Low seasonNovember
Cheapest flight$194
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $260 on average. Morning departures are around 11% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $373.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $227 one-way - $299 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
6.5Food
7.5Boarding
8.0Crew
7.2Comfort
6.9Entertainment
Airline reviews

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

4.0 OkayFernando, Aug 2025DFW - SBA
Read more American Airlines reviews

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

Any flight to ORD after about 2pm this summer has been challenging. Flight was delayed getting in (coming from ORD) and that led to it not leaving before a ground stop due to lightening before they could fuel the plane, and so forth. They made up some time but we were still late in arriving at ORD, and that led to missed connections.

Food was ok, but not as good as I have had before on AA.

No issues. They did change our gate FOUR times in about 30 minutes which was mildly annoying but the flight was fine.

Great flight. No issues at all. I still think boarding could be more efficient but otherwise, a good experience.

Pretty good. The food was just mediocre, the boarding and crew were good.

The comfort of the seats was great, the crew eased my child’s anxieties and the fact that I had full cans of my beverage choice was great.

My flight got switched and my prepaid bag didnt transfer over properly so I paid to check ANOTHER BAG. I was placed in a middle seat and it was just miserable. At least it was a bulkhead row so I had legroom. The flight just never seem3d to end

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports

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