$185 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$239
Charlotte
Charlottenonstop$359
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$239
Charlotte
Charlottenonstop$359

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Tue, Apr 7 - Wed, Apr 15
Delta Logo
7:51 pm - 12:04 am
ROA
-
MYR
4h 13m
1 stop
Delta Logo
6:00 am - 10:28 am
MYR
-
ROA
4h 28m
1 stop
$239Delta
Tue, Apr 7 - Sat, Apr 11
Delta Logo
6:00 am - 9:57 am
ROA
-
CHS
3h 57m
1 stop
Delta Logo
6:09 pm - 12:04 am
CHS
-
ROA
5h 55m
1 stop
$249Delta
Tue, Apr 7 - Sat, Apr 11
Delta Logo
7:51 pm - 12:04 am
ROA
-
MYR
4h 13m
1 stop
Delta Logo
6:54 pm - 12:04 am
MYR
-
ROA
5h 10m
1 stop
$264Delta
Tue, Apr 7 - Wed, Apr 15
American Airlines Logo
7:33 pm - 11:02 pm
ROA
-
MYR
3h 29m
1 stop
American Airlines Logo
6:04 am - 12:33 pm
MYR
-
ROA
6h 29m
2 stops
$304American Airlines
Tue, Feb 10 - Sat, Feb 14
United Airlines Logo
2:55 pm - 7:04 pm
ROA
-
CHS
4h 09m
1 stop
United Airlines Logo
2:48 pm - 8:07 pm
CHS
-
ROA
5h 19m
1 stop
$319United Airlines
Fri, Apr 10 - Tue, Apr 14
American Airlines Logo
5:00 am - 8:24 am
ROA
-
MYR
3h 24m
1 stop
American Airlines Logo
6:04 am - 9:46 am
MYR
-
ROA
3h 42m
1 stop
$324American Airlines
Thu, Feb 12 - Mon, Feb 16
American Airlines Logo
5:00 am - 8:40 am
ROA
-
MYR
3h 40m
1 stop
American Airlines Logo
3:17 pm - 9:25 pm
MYR
-
ROA
6h 08m
1 stop
$329American Airlines
Sat, Apr 11 - Tue, Apr 14
American Airlines Logo
7:45 pm - 11:59 pm
ROA
-
CHS
4h 14m
1 stop
American Airlines Logo
4:25 pm - 10:56 pm
CHS
-
ROA
6h 31m
1 stop
$334American Airlines
Sat, Mar 28 - Fri, Apr 3
United Airlines Logo
7:50 pm - 11:57 pm
ROA
-
CLT
4h 07m
1 stop
United Airlines Logo
10:13 am - 2:13 pm
CLT
-
ROA
4h 00m
1 stop
$379United Airlines
Fri, Apr 10 - Sun, Apr 12
United Airlines Logo
10:34 am - 2:05 pm
ROA
-
CLT
3h 31m
1 stop
United Airlines Logo
6:00 am - 9:49 am
CLT
-
ROA
3h 49m
1 stop
$399United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Roanoke to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South Carolina were found on Delta ($239) and American Airlines ($359).

Good to know

Low seasonApril
Cheapest flight$185
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $280 one-way - $340 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11197 reviews
8.0Crew
6.9Entertainment
7.5Boarding
7.2Comfort
6.4Food
Airline reviews

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

2.0 MediocreCem, Jan 2026
MIA - DEN
Read more American Airlines reviews

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

one crew said "he" didn't serve double alcohol drinks for travelers in exit rows. crew on prior flight did. Is this a AA rule, and the prior crew was being nice? Also, I think we deserve more than a 25% refund for losing first class seats when rescheduling a flight due to weather

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

2 hour delay due to equipment failure. No updates via the app and airport screens (which continued to show a departure time in the past). AA eventually switched planes and the new plane was not catered or cleaned correctly.

I booked an aisle seat and was given a middle. At 6'4" 230lbs, it is not ideal to fly in the middle row for myself and passengers.

Trip delayed for 2 hours because of rain. We boarded and have to get down the flight and reboard again.

The aircraft had several problems - from excess fuel to non operational ac. Two hours of delay in Chicago could have been avoided with proper planning and aircraft maintenance.

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports