$122 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
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Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$222
Charlotte
Charlottenonstop$303
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$222
Charlotte
Charlottenonstop$303

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Fri, Jan 2 - Sat, Jan 10
American Airlines Logo
7:07 pm - 11:55 pm
ROA
-
MYR
4h 48m1 stop
American Airlines Logo
6:23 am - 9:41 am
MYR
-
ROA
3h 18m1 stop
$222American Airlines
Mon, Apr 13 - Mon, Apr 20
Delta Logo
7:50 pm - 11:51 pm
ROA
-
CHS
4h 01m1 stop
Delta Logo
7:59 pm - 11:49 pm
CHS
-
ROA
3h 50m1 stop
$249Delta
Sun, Jan 4 - Tue, Mar 17
Delta Logo
6:00 am - 12:31 pm
ROA
-
MYR
6h 31m1 stop
Delta Logo
6:58 pm - 12:04 am
MYR
-
ROA
5h 06m1 stop
$259Delta
Thu, Jan 1 - Sun, Jan 4
American Airlines Logo
9:08 am - 3:43 pm
ROA
-
CHS
6h 35m1 stop
American Airlines Logo
5:10 am - 8:42 am
CHS
-
ROA
3h 32m1 stop
$269American Airlines
Fri, Jan 2 - Sun, Jan 4
American Airlines Logo
5:00 am - 8:35 am
ROA
-
CHS
3h 35m1 stop
American Airlines Logo
5:10 am - 8:42 am
CHS
-
ROA
3h 32m1 stop
$274American Airlines
Tue, Dec 30 - Sun, Jan 4
Delta Logo
7:03 pm - 10:50 pm
ROA
-
MYR
3h 47m1 stop
Delta Logo
6:59 pm - 12:08 am
MYR
-
ROA
5h 09m1 stop
$274Delta
Thu, Jan 1 - Wed, Jan 7
American Airlines Logo
6:00 am - 9:20 am
ROA
-
MYR
3h 20m1 stop
American Airlines Logo
5:29 pm - 10:53 pm
MYR
-
ROA
5h 24m1 stop
$282American Airlines
Mon, Dec 22 - Thu, Dec 25
United Airlines Logo
6:15 am - 10:24 am
ROA
-
CHS
4h 09m1 stop
United Airlines Logo
10:00 am - 2:16 pm
CHS
-
ROA
4h 16m1 stop
$299United Airlines
Mon, Apr 13 - Sat, Apr 18
United Airlines Logo
8:00 pm - 11:59 pm
ROA
-
CHS
3h 59m1 stop
United Airlines Logo
6:00 am - 9:34 am
CHS
-
ROA
3h 34m1 stop
$309United Airlines
Sat, May 2 - Wed, May 6
United Airlines Logo
7:59 pm - 11:54 pm
ROA
-
CHS
3h 55m1 stop
United Airlines Logo
6:00 am - 9:48 am
CHS
-
ROA
3h 48m1 stop
$314United Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Roanoke to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Roanoke to South Carolina departing in April.

What’s the cheapest day of the week to fly from Roanoke to South Carolina?

The average price of all round-trip flights from Roanoke to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Roanoke to South Carolina, you should consider leaving on a Saturday and avoid Mondays if you are looking for the best rates. For your return to Roanoke, you’ll find the best rates on Saturdays and the most expensive ones on Mondays.

Find deals

Good to know

Low seasonJanuary
Cheapest flight$122
Best time to beat the crowds with an average 40% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $260 on average. Morning departures are around 11% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $373.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $278 one-way - $374 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11052 reviews
7.2Comfort
6.9Entertainment
7.5Boarding
8.0Crew
6.5Food
Airline reviews

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

2.0 MediocreJohn, Dec 2025
GSO - ORD
Read more American Airlines reviews

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

It was fine. No drinks nor snacks offered though. I thought that was unusual.

I liked the humor of the captain and crew on the flight from Flagstaff to Dallas. They were humorous.

AA delayed the flight for 3 hours and 50 minutes, but delayed the last 2 hours, 30 minutes at a time, so if we knew before, could have stayed at home and worked instead of being at the airport wasting time... The plane's crew was excellent, not their fault.

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports

Roanoke (ROA)