$190 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
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Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$239
Charlotte
Charlottenonstop$339
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$239
Charlotte
Charlottenonstop$339

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Sun, Feb 1 - Sat, Feb 7
American Airlines Logo
3:30 pm - 8:54 pm
ROA
-
MYR
5h 24m1 stop
American Airlines Logo
1:53 pm - 6:58 pm
MYR
-
ROA
5h 05m1 stop
$239American Airlines
Thu, Jan 22 - Mon, Jan 26
Delta Logo
6:00 am - 9:46 am
ROA
-
MYR
3h 46m1 stop
Delta Logo
6:54 pm - 12:04 am
MYR
-
ROA
5h 10m1 stop
$249Delta
Fri, Jan 30 - Sun, Feb 1
Delta Logo
7:59 pm - 11:57 pm
ROA
-
CHS
3h 58m1 stop
Delta Logo
5:25 am - 10:39 am
CHS
-
ROA
5h 14m1 stop
$249Delta
Wed, Jan 21 - Sun, Jan 25
Delta Logo
11:24 am - 4:06 pm
ROA
-
CHS
4h 42m1 stop
Delta Logo
7:00 pm - 12:04 am
CHS
-
ROA
5h 04m1 stop
$259Delta
Thu, Mar 12 - Wed, Mar 18
American Airlines Logo
8:00 pm - 11:55 pm
ROA
-
MYR
3h 55m1 stop
American Airlines Logo
6:22 pm - 11:45 pm
MYR
-
ROA
5h 23m1 stop
$289American Airlines
Fri, Mar 13 - Mon, Mar 16
Delta Logo
7:51 pm - 12:16 am
ROA
-
CHS
4h 25m1 stop
Delta Logo
7:58 pm - 12:04 am
CHS
-
ROA
4h 06m1 stop
$299Delta
Sat, Jan 31 - Tue, Feb 3
United Airlines Logo
10:15 am - 2:48 pm
ROA
-
CHS
4h 33m1 stop
United Airlines Logo
2:58 pm - 7:31 pm
CHS
-
ROA
4h 33m1 stop
$309United Airlines
Wed, Jan 21 - Sun, Jan 25
United Airlines Logo
6:45 am - 2:02 pm
ROA
-
CHS
7h 17m1 stop
United Airlines Logo
6:05 am - 12:05 pm
CHS
-
ROA
6h 00m1 stop
$319United Airlines
Sat, Feb 21 - Sun, Feb 22
American Airlines Logo
5:00 am - 6:21 am
ROA
-
CLT
1h 21mnonstop
American Airlines Logo
9:08 am - 10:37 am
CLT
-
ROA
1h 29mnonstop
$339American Airlines
Wed, Feb 25 - Sat, Feb 28
American Airlines Logo
5:00 am - 9:36 am
ROA
-
MYR
4h 36m1 stop
American Airlines Logo
12:43 pm - 8:30 pm
MYR
-
ROA
7h 47m2 stops
$342American Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Roanoke and South Carolina?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Roanoke to South Carolina.

There is just one airline that flies from Roanoke to South Carolina direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is to Charleston (CHS) and costs $228.

Which airlines provide the cheapest flights from Roanoke to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Roanoke to South Carolina were found on American Airlines ($239) and Delta ($239).

Find deals

Good to know

Low seasonJanuary
Cheapest flight$179
Best time to beat the crowds with an average 40% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $218 one-way - $331 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11094 reviews
6.9Entertainment
7.5Boarding
8.0Crew
7.2Comfort
6.4Food
Airline reviews

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

8.0 ExcellentR, Jan 2026
PBI - CLT
Read more American Airlines reviews

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

The flight was on time and arrived early. The crew were friendly and helpful.

My carry on baggage was damaged. Entire trip, I had to carry the baggage. When complained to the boarding crew, they got mad at me and still asked me to valet check in the cabin baggage. Rude boarding crew!!!

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

Nothing to write home about, average flight experience. Seats were spacious enough, crew friendly enough. Loved the AA entertainment/wifi service.

Kayak was among the missing. There was not the usual advice regarding next gate after arriving in Dallas. No communication after the reminder to check in before the Moline flight. What happened?

They should have allowed for extra time to de-ice the plane before boarding passengers. This delayed us about 10-15 mins after we boarded. Overall experience was fine. Crew was friendly and on top of everything. We didn’t have any issues during the flight.

Experience was good. We were delayed in leaving by 15 mins because the flight was waiting on a family that was late in getting to the gate. Food and drink options were as expected. I highly recommend checking in ahead of time using the airline’s app so that it’s quicker to get your luggage tags as soon as you arrive at the terminal. No more waiting in long lines!

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

We never made it due to delays on both ends. Gate attendant said it was mechanical but the system said otherwise, so no compensation. That’s not right.

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports

Roanoke (ROA)