$216 Find Cheap Flights from Roanoke to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Roanoke to South Carolina departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Roanoke to South Carolina, as well as popular online travel agencies
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Cheap Flights from Roanoke to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$259
Charlotte
Charlottenonstop$359
Charleston
Charleston1 stop$249
Myrtle Beach
Myrtle Beach1 stop$259
Charlotte
Charlottenonstop$359

Book Cheap Roanoke to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Roanoke to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Roanoke to South Carolina

Sat, Apr 25 - Wed, Apr 29
United Airlines Logo
2:55 pm - 7:04 pm
ROA
-
CHS
4h 09m
1 stop
United Airlines Logo
10:00 am - 2:13 pm
CHS
-
ROA
4h 13m
1 stop
$249United Airlines
Tue, Mar 31 - Tue, Apr 7
American Airlines Logo
7:23 pm - 10:56 pm
ROA
-
MYR
3h 33m
1 stop
American Airlines Logo
6:04 am - 11:10 am
MYR
-
ROA
5h 06m
1 stop
$259American Airlines
Sat, Mar 28 - Wed, Apr 1
American Airlines Logo
8:00 pm - 11:55 pm
ROA
-
MYR
3h 55m
1 stop
American Airlines Logo
5:10 am - 10:37 am
MYR
-
ROA
5h 27m
1 stop
$288American Airlines
Fri, Apr 3 - Fri, Apr 10
American Airlines Logo
8:00 pm - 11:55 pm
ROA
-
MYR
3h 55m
1 stop
American Airlines Logo
5:00 am - 8:36 am
MYR
-
ROA
3h 36m
1 stop
$293American Airlines
Tue, Mar 31 - Tue, Apr 7
American Airlines Logo
6:00 am - 9:36 am
ROA
-
MYR
3h 36m
1 stop
American Airlines Logo
10:33 am - 5:33 pm
MYR
-
ROA
7h 00m
2 stops
$313American Airlines
Wed, Aug 26 - Sat, Aug 29
United Airlines Logo
6:15 am - 10:02 am
ROA
-
CHS
3h 47m
1 stop
United Airlines Logo
10:00 am - 2:18 pm
CHS
-
ROA
4h 18m
1 stop
$329United Airlines
Sun, Apr 12 - Mon, Apr 20
Delta Logo
6:00 am - 9:33 am
ROA
-
MYR
3h 33m
1 stop
Delta Logo
7:03 pm - 12:25 am
MYR
-
ROA
5h 22m
1 stop
$347Delta
Tue, Mar 31 - Sat, Apr 4
Delta Logo
7:51 pm - 11:55 pm
ROA
-
CHS
4h 04m
1 stop
Delta Logo
5:27 am - 10:27 am
CHS
-
ROA
5h 00m
1 stop
$364Delta
Fri, May 15 - Sun, May 17
Multiple Airlines Logo
4:52 pm - 8:09 am
ROA
-
CLT
15h 17m
1 stop
Multiple Airlines Logo
10:39 pm - 2:19 pm
CLT
-
ROA
15h 40m
2 stops
$381Multiple Airlines
Fri, Mar 27 - Wed, Apr 1
Multiple Airlines Logo
4:11 pm - 9:00 am
ROA
-
CLT
16h 49m
1 stop
Multiple Airlines Logo
1:20 pm - 2:33 pm
CLT
-
ROA
25h 13m
2 stops
$391Multiple Airlines
Booking Insights

KAYAK's insights & trends for Roanoke to South Carolina flights

Get data-powered insights and trends into flights from Roanoke to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Roanoke to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Roanoke to South Carolina departing in April.

Good to know

Low seasonJune
Cheapest flight$197
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Roanoke to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Roanoke to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Roanoke to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Roanoke to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Roanoke to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Roanoke to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Roanoke to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Roanoke to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Roanoke to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Roanoke to the following destinations at these prices or less: Charlotte $327 one-way - $375 round-trip

Reviews of the top airline flying from Roanoke to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Roanoke to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Roanoke to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11392 reviews
6.9Entertainment
8.0Crew
6.4Food
7.2Comfort
7.5Boarding
Airline reviews

They are rarely on time! Very hard to plan your travels when flights or connections keep getting delayed.

4.0 OkayPreethi, Mar 2026
SJC - DFW
Read more American Airlines reviews

They are rarely on time! Very hard to plan your travels when flights or connections keep getting delayed.

Flight delay for mechanical. Inbound arrived on time. No one said why mechanical delay.

Forced to check bags. Crew uninterested in collecting trash. Unclean seats.

why would I bother with this airline and pick seats when I am asked to move for a weight imbalance

Flight pulled out on time but sat on runway for 30 mins. It was extremely cold in the aircraft despite wearing a winter coat. Surprisingly they had a vegetarian meal but could have some better snack choices for a 8 hour flight.

We had a male flight attendant who was super attentive and wonderful! Very professional. I have both gluten and dairy intolerance, and was only able to get a gluten free part, and not the dairy free part of the meal. Easy to order ahead of time and I appreciate being able to do that.

Snow delayed boarding several times, which I understand happens. Issue I had was that after we did board, pilot told us we were going to roll out to be de-iced, then on our way. We were de-iced once, taxied to the tarmac and then stopped. Sat for another 30 minutes or so, the another de-icing. Then we rolled out to a parking spot, only to sit for another hour due to a traffic stop in DCA, which I'm confident they knew would happen before we boarded. Pilot gave no updates other than we had to hold, attendants did speak to the crew, but when asked, said the pilot would be updating us. We on the ground in the plane waiting for over 2 hours. They did communicate that bathrooms would be open, but no other news until we left. Would have been better to be up front about status.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

Delayed initially because they couldn’t print the flight details. Poor instruction on delay. When I got on the plane the flight attendant argued with me about whether my carry on would fit (it did, although she didn’t acknowledge that). No greeting (other than arguing with me) getting on or off the plane.

Everything you need to know for your flight from Roanoke to South Carolina

Information on your arrival and departure airports