$337 Find Cheap Flights from Santa Fe to South Carolina - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Santa Fe to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Sort by: Cheapest
Charlotte
6h 09m2 stops
from $357per person
Charleston
5h 57m2 stops
from $488per person
Savannah
6h 05m2 stops
from $617per person
Greenville
6h 03m3 stops
from $626per person
Booking Insights

KAYAK's insights & trends for Santa Fe to South Carolina flights

Get data-powered insights and trends into flights from Santa Fe to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Santa Fe to South Carolina?

In the past 5 days, the cheapest round-trip tickets from Santa Fe to South Carolina were found on American Airlines ($392) and United Airlines ($453).

Good to know

Cheapest flight

$337
Flight from Santa Fe to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Santa Fe to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Fe to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Fe to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santa Fe to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Fe to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santa Fe to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Fe to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santa Fe to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Fe to South Carolina

 
Need help choosing which airline to fly with from Santa Fe to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
American AirlinesOverall score based on 12073 reviews
6.4Food
7.4Boarding
7.9Crew
7.2Comfort
6.8Entertainment
Airline reviews

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

4.0 OkayCaleb, Jun 2026
Read more American Airlines reviews

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

They cancelled two flight and got us onto another airline, which was also delayed.

Boarding and crew were great. Everything was. On time. The 737 was Incredibly Uncomfortable!! Too tight in seat area for one, but, the real problem was that the seats were AWFUL. After an 8 hour flight from Dallas to Madrid my lower back was miserable and I am fit: I never have back problems. It took 2 days to recover. Honestly I can’t recommend AA for long distance flights. Plus for a $1200+ ticket they wanted $30 for 2 hours of internet. Thank you for listening.

A nearly half-hour delay to board/depart meant that our connection in DFW was less than 30 minutes. If the flight attendants would have made an announcement to the flight to allow those with close connections to de-plane first it would have helped, but nothing. We *barely* made our connection, with no time to eat or user the restroom between flights.

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

My first flight from Santa Fe was 1.5 hours delayed, I missed the connecting flight. I got tickets to the next flight to San Francisco. The flight is over two hours delayed and we had to change the plane. I will never fly American Airlines again. Absolutely horrible experience!

More options for your flight from Santa Fe to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental