SCL - VVI

$156 Find Cheap Flights from Santiago to Santa Cruz de la Sierra - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Santa Cruz de la Sierra departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Santa Cruz de la Sierra, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$396
Typical prices: $369-$441
Aerolineas Argentinas
Fri 9/18Mon 9/21
SCL - VVI • 1 stop
Cheapest non-stop
$429
Typical prices: $339-$434
BoA
Tue 7/21Tue 7/28
SCL - VVI • Non-stop
Nonstop flights
2 days a week
Wed, Sat
You can fly direct with BoA and LATAM Airlines. Average duration is 3h 17m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
Aerolineas Argentinas
Cheapest • from $396 (round-trip)
LATAM Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Buenos Aires (AEP)
Cheapest • Avg $367 (round-trip)
Buenos Aires (AEP)
Shortest trip • 10h 35m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
BoA
Most punctual • 61% on-time
Night flights
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 33% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
October
Cheapest • 9% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santiago to Santa Cruz de la Sierra (SCL-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Santa Cruz de la Sierra

Fri, Sep 18 - Mon, Sep 21
Aerolineas Argentinas Logo
2:35 pm - 1:10 am
SCL
-
VVI
11h 35m
1 stop
Aerolineas Argentinas Logo
2:20 am - 1:45 pm
VVI
-
SCL
10h 25m
1 stop
$396Aerolineas Argentinas
Fri, Jul 17 - Sat, Jul 18
LATAM Airlines Logo
12:32 pm - 4:35 am
SCL
-
VVI
16h 03m
1 stop
LATAM Airlines Logo
11:15 am - 2:24 pm
VVI
-
SCL
3h 09mnonstop
$422LATAM Airlines
Tue, Jul 21 - Tue, Jul 28
BoA Logo
1:25 am - 4:40 am
SCL
-
VVI
3h 15mnonstop
BoA Logo
9:15 pm - 12:30 am
VVI
-
SCL
3h 15mnonstop
$429BoA
Tue, Jul 28 - Tue, Aug 4
BoA Logo
1:25 am - 4:40 am
SCL
-
VVI
3h 15mnonstop
BoA Logo
9:15 pm - 12:30 am
VVI
-
SCL
3h 15mnonstop
$430BoA
Wed, Aug 12 - Wed, Sep 2
LATAM Airlines Logo
4:36 am - 7:56 am
SCL
-
VVI
3h 20mnonstop
LATAM Airlines Logo
8:41 am - 11:50 am
VVI
-
SCL
3h 09mnonstop
$453LATAM Airlines
Fri, Jul 24 - Fri, Jul 31
Multiple Airlines Logo
9:15 am - 1:10 am
SCL
-
VVI
15h 55m
1 stop
Multiple Airlines Logo
9:15 pm - 12:30 am
VVI
-
SCL
3h 15mnonstop
$462Multiple Airlines
Wed, Aug 12 - Wed, Sep 2
LATAM Airlines Logo
4:50 pm - 4:35 am
SCL
-
VVI
11h 45m
1 stop
LATAM Airlines Logo
8:41 am - 11:50 am
VVI
-
SCL
3h 09mnonstop
$478LATAM Airlines
Wed, Aug 12 - Wed, Sep 2
LATAM Airlines Logo
4:36 am - 7:56 am
SCL
-
VVI
3h 20mnonstop
LATAM Airlines Logo
8:41 am - 11:50 am
VVI
-
SCL
3h 09mnonstop
$479LATAM Airlines
Sat, Jul 11 - Sat, Aug 1
Multiple Airlines Logo
6:45 pm - 8:35 am
SCL
-
VVI
13h 50m
2 stops
Multiple Airlines Logo
11:15 am - 2:24 pm
VVI
-
SCL
3h 09mnonstop
$480Multiple Airlines
Wed, Aug 12 - Wed, Sep 2
LATAM Airlines Logo
4:50 pm - 4:35 am
SCL
-
VVI
11h 45m
1 stop
LATAM Airlines Logo
8:41 am - 11:50 am
VVI
-
SCL
3h 09mnonstop
$485LATAM Airlines
Booking Insights

KAYAK's insights & trends for Santiago to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Santiago to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to Santa Cruz de la Sierra?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to Santa Cruz de la Sierra departing in September.

What’s the cheapest day of the week to fly from Santiago to Santa Cruz de la Sierra?

The average price of all round-trip flights from Santiago to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

For Santiago to Santa Cruz de la Sierra, Monday is the cheapest day to fly on average and Wednesday is the most expensive. Flying from Santa Cruz de la Sierra back to Santiago, the best deals are generally found on Wednesday, with Sunday being the most expensive.

What is the cheapest month to fly from Santiago to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Santa Cruz de la Sierra is October, where tickets cost $379 (return) on average. On the other hand, the most expensive months are January and December, where the average cost of round-trip tickets is $477 and $460 respectively.

Can I save money by flying with a layover from Santiago to Santa Cruz de la Sierra?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $367, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santiago to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Santa Cruz de la Sierra, you should book around 7 weeks before departure, which saves you about 33% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 22 weeks before departure.

Find deals

Good to know

Low seasonJune
Cheapest flight$156
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Santiago to Santa Cruz de la Sierra

When to book flights from Santiago to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Santiago to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santiago to Santa Cruz de la Sierra

  • How many flights are there between Santiago and Santa Cruz de la Sierra per day?

    Each day, there are between 1 and 2 nonstop flights that take off from Santiago and land in Santa Cruz de la Sierra, with an average flight time of 3h 17m. The most common departure time is 1:00 am and most flights take off at night. Each week, there are 3 flights. The most frequent day of departure is Wednesday, when 67% of all weekly flights depart. The fewest flights depart on a Saturday.

  • What is the cheapest flight from Santiago to Santa Cruz de la Sierra?

    In the last 5 days, the lowest price for a flight from Santiago to Santa Cruz de la Sierra was $156 for a one-way ticket and $396 for a round-trip.

  • Do I need a passport to fly between Santiago and Santa Cruz de la Sierra?

    A passport is required to fly from Santiago to Santa Cruz de la Sierra.

  • Which aircraft models fly most regularly from Santiago to Santa Cruz de la Sierra?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Santiago to Santa Cruz de la Sierra flight route.

  • On which days can I fly direct from Santiago to Santa Cruz de la Sierra?

    You can catch a nonstop flight from Santiago to Santa Cruz de la Sierra on on Wednesday, and Saturday.

  • How does KAYAK find such low prices on flights from Santiago to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Santiago with another airline. Booking your flights between Santiago and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Prefer to fly direct from Santiago to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Santa Cruz de la Sierra Viru Viru Intl

Wednesday

BoA,LATAM Airlines

BoA,LATAM Airlines

Saturday

BoA

BoA

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Santiago Arturo Merino Benitez

Tuesday

BoA

BoA

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

BoA

BoA

Saturday

LATAM Airlines

LATAM Airlines

See more direct flights

Reviews of the top airline flying from Santiago to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1944 reviews
7.0Entertainment
7.5Boarding
7.3Comfort
8.0Crew
6.7Food
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
ANF - SCL
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

Great customer service, very accommodating. (Check in) Smooth flight, thank you Pilots. Only negative was one working bathroom in first class. Atlanta Base flight attendants were wonderful. Thank you for your smiling faces Delta..

The seats are getting smaller and smaller. Very uncomfortable trip. More than in other airlines

I do not speak Spanish or read in Spanish When asking for help, people were hard to find they spoke quickly and pointed a lot directions for where to go and what to do we’re unclear. Which made my traveling uneasy.

Flight was great Customer service was questionable until we found someone at checkin to help us. One young lady took all our passports disappeared for 15 minutes, came back with nothing done, handed to someone else and left for lunch. Very complacent. Baggage was very expensive until we went to the service counter and a separate person helped us. Even with platinum status they wouldn’t allow free bags. We will continue to fly Delta as our preferred carrier but will avoid checking in with Latam. Dr. Armand Radke

It was ok for the most part, it is missing something

Everything you need to know for your flight from Santiago to Santa Cruz de la Sierra

Information on your arrival and departure airports

Santiago (SCL)
Santa Cruz de la Sierra (VVI)