SDQ - TYS

$346 Find Cheap Flights from Santo Domingo to Knoxville - Compare and Save

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Everything you should know

Cheapest round-trip
$594
Typical prices: $540-$669
Multiple Airlines
Tue 12/18Fri 12/28
SDQ - TYS • 1 stop
Cheapest one-way
$346
Typical prices: $375-$467
Multiple Airlines
Wed 10/17
SDQ - TYS • 3 stops
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and Knoxville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
November
Cheapest • 7% price drop
April
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Fort Lauderdale (FLL)
Cheapest • Avg $421 (round-trip)
Miami (MIA)
Shortest trip • 6h 57m (one-way)
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Insights
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Flight Deals

Cheap Flights from Santo Domingo to Knoxville (SDQ-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Knoxville

Fri, Dec 18 - Mon, Dec 28
Multiple Airlines Logo
12:26 pm - 7:15 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
7h 49m1 stop Philadelphia
Multiple Airlines Logo
1:53 pm - 7:04 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
28h 11m1 stop Orlando
$594Multiple Airlines
Fri, Dec 18 - Mon, Dec 28
Multiple Airlines Logo
12:26 pm - 7:15 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
7h 49m1 stop Philadelphia
Multiple Airlines Logo
1:53 pm - 11:11 amTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
20h 18m2 stops Orlando Philadelphia
$622Multiple Airlines
Tue, Mar 2 - Thu, Mar 11
American Airlines Logo
11:02 am - 6:36 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
8h 34m1 stop Miami
American Airlines Logo
7:39 pm - 10:00 amTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
13h 21m1 stop Miami
$635American Airlines
Tue, Mar 2 - Thu, Mar 11
American Airlines Logo
11:02 am - 8:03 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
10h 01m2 stops Miami Charlotte Douglas
American Airlines Logo
6:02 am - 2:00 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
6h 58m1 stop Philadelphia
$639American Airlines
Tue, Mar 2 - Thu, Mar 11
American Airlines Logo
7:00 am - 5:12 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
11h 12m2 stops Miami Charlotte Douglas
American Airlines Logo
5:52 am - 4:05 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
9h 13m2 stops Washington, D.C. Reagan-National Miami
$639American Airlines
Fri, Dec 25 - Sat, Jan 16
United Airlines Logo
2:50 am - 9:44 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
19h 54m1 stop Houston George Bush Intcntl
United Airlines Logo
12:20 pm - 1:41 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
24h 21m1 stop Newark
$666United Airlines
Mon, Oct 19 - Mon, Oct 26
United Airlines Logo
6:00 am - 8:45 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
14h 45m1 stop Newark
United Airlines Logo
4:30 pm - 12:41 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
20h 11m1 stop Newark
$680United Airlines
Sat, Dec 26 - Sat, Jan 16
Delta Logo
4:00 pm - 11:50 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
8h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 7:20 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
12h 20m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl
$834Delta
Sat, Dec 26 - Sat, Jan 16
Delta Logo
4:00 pm - 11:50 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
8h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 2:15 pmTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
7h 15m1 stop Atlanta Hartsfield-Jackson
$940Delta
Sat, Dec 26 - Sat, Jan 16
Delta Logo
4:00 pm - 11:50 pmSDQ  Santo Domingo Las Americas-TYS Knoxville McGhee Tyson
8h 50m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:05 am - 12:30 amTYS  Knoxville McGhee Tyson-SDQ Santo Domingo Las Americas
13h 25m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl
$1,005Delta
Booking Insights

Price, demand and travel trends for Santo Domingo to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Santo Domingo to Knoxville with more confidence.

What's the cheapest day of the week to fly from Santo Domingo to Knoxville?

Saturday is the cheapest day of the week to fly from Santo Domingo to Knoxville, it is 5% cheaper than the average day. Sunday is the most expensive day with flight prices 80% higher than average. Based on deals found by KAYAK users in the last 12 months.

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Key details for Santo Domingo to Knoxville flights

Low season

July

Cheapest flight

$346
Best time to beat the crowds but there is an average 18% increase in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Santo Domingo to Knoxville

When to book flights from Santo Domingo to Knoxville

Are your dates flexible? Find out the best times to travel from Santo Domingo to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santo Domingo to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Santo Domingo to Knoxville?

    Flights from Santo Domingo to Knoxville usually depart from Santo Domingo Las Americas (SDQ) and arrive at Knoxville McGhee Tyson (TYS).

  • What cabin classes can I book on flights from Santo Domingo to Knoxville?

    Only Economy Class is available on flights from Santo Domingo to Knoxville.

  • Which airports do connecting flights from Santo Domingo to Knoxville pass through?

    One-stop flights from Santo Domingo to Knoxville most commonly connect through:

    • Miami (MIA) - 79% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 14% of one-stop connections
    • Fort Lauderdale (FLL) - 4% of one-stop connections
    • Philadelphia (PHL) - 3% of one-stop connections

    Miami (MIA) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Santo Domingo to Knoxville?

    On the Santo Domingo to Knoxville route, being flexible with your departure day can save you up to 48%. Saturday is the cheapest day at $540 round-trip on average, while Sunday is the most expensive at $1,023: a $483 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How long is a flight from Santo Domingo to Knoxville?

    A nonstop flight from Santo Domingo to Knoxville takes 0h 00m, covering 1,484 miles.

  • Do I need a passport to fly from Santo Domingo to Knoxville?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Santo Domingo to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $594 to $5,326. That means the highest observed fare was about 9x higher than the lowest one.

  • How are flight prices from Santo Domingo to Knoxville looking right now?

    One-way fares from Santo Domingo to Knoxville are currently in line with typical prices for this route. Average one-way fares are about $418.

  • How much time can I save by choosing a different layover airport from Santo Domingo to Knoxville?

    Flying via Miami (MIA) gives the shortest average 1-stop total travel time at 6h 57m, compared with 7h 42m via Atlanta Hartsfield-Jackson (ATL) and 8h 50m via Philadelphia (PHL).

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Payless

  • How much should I expect to pay for a Santo Domingo to Knoxville flight?

    Round-trip flights from Santo Domingo to Knoxville range from $540 to $669, with an average of $566 over the past 12 months. Anything below $540 counts as a good deal.

Your guide to booking Santo Domingo to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Saturday departure instead of Sunday. On this route, Saturday flights average $540 - about $483 less than Sunday (47% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santo Domingo to Knoxville trip for November. Fares historically average $528 round-trip in that month - typically $495 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Santo Domingo to Knoxville

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