SDQ - TYS

$238 Find Cheap Flights from Santo Domingo to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Knoxville departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Knoxville, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$559
Multiple Airlines
Fri 6/5Sun 6/7
SDQ - TYS • 1 stop
Cheapest one-way
$235
Multiple Airlines
Wed 5/13
SDQ - TYS • 2 stops
Top airlines
Cheapest • from $659 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and Knoxville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $573 (round-trip)
Shortest trip • 7h 34m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 100% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Knoxville (SDQ-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Knoxville

Fri, Jun 5 - Sun, Jun 7
Multiple Airlines Logo
6:30 am - 12:16 pm
SDQ
-
TYS
29h 46m
1 stop
Multiple Airlines Logo
7:30 am - 2:35 am
TYS
-
SDQ
19h 05m
1 stop
$559Multiple Airlines
Fri, Jun 5 - Sun, Jun 7
Multiple Airlines Logo
7:10 pm - 11:49 am
SDQ
-
TYS
16h 39m
1 stop
Multiple Airlines Logo
1:01 pm - 10:15 pm
TYS
-
SDQ
9h 14m
2 stops
$583Multiple Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
10:29 am - 11:59 pm
SDQ
-
TYS
13h 30m
1 stop
American Airlines Logo
6:12 am - 6:35 pm
TYS
-
SDQ
12h 23m
2 stops
$659American Airlines
Mon, Oct 26 - Sat, Oct 31
Delta Logo
2:56 pm - 9:45 pm
SDQ
-
TYS
6h 49m
1 stop
Delta Logo
5:30 am - 1:41 pm
TYS
-
SDQ
8h 11m
1 stop
$665Delta
Fri, Jul 17 - Wed, Aug 5
American Airlines Logo
7:00 am - 11:59 pm
SDQ
-
TYS
16h 59m
1 stop
American Airlines Logo
7:00 am - 6:39 pm
TYS
-
SDQ
11h 39m
1 stop
$667American Airlines
Fri, Jul 17 - Wed, Aug 5
American Airlines Logo
7:00 am - 11:59 pm
SDQ
-
TYS
16h 59m
1 stop
American Airlines Logo
6:13 am - 6:39 pm
TYS
-
SDQ
12h 26m
2 stops
$671American Airlines
Fri, Jun 5 - Sun, Jun 7
American Airlines Logo
7:35 pm - 10:36 am
SDQ
-
TYS
15h 01m
2 stops
American Airlines Logo
7:59 pm - 9:24 am
TYS
-
SDQ
13h 25m
2 stops
$682American Airlines
Mon, Oct 26 - Sat, Oct 31
American Airlines Logo
8:00 am - 11:30 pm
SDQ
-
TYS
15h 30m
2 stops
American Airlines Logo
6:08 am - 7:55 pm
TYS
-
SDQ
13h 47m
2 stops
$688American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
7:35 pm - 10:36 am
SDQ
-
TYS
15h 01m
2 stops
American Airlines Logo
6:12 am - 6:35 pm
TYS
-
SDQ
12h 23m
2 stops
$712American Airlines
Tue, Jun 16 - Tue, Jun 23
American Airlines Logo
10:29 am - 11:59 pm
SDQ
-
TYS
13h 30m
1 stop
American Airlines Logo
7:03 pm - 12:45 pm
TYS
-
SDQ
17h 42m
1 stop
$796American Airlines
Booking Insights

KAYAK's insights & trends for Santo Domingo to Knoxville flights

Get data-powered insights and trends into flights from Santo Domingo to Knoxville to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to Knoxville?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to Knoxville departing in June.

What is the cheapest month to fly from Santo Domingo to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Knoxville is June, where tickets cost $0 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $1,023 and $780 respectively.

Good to know

Low seasonSeptember
Cheapest flight$235
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly and prices are also 18% lower on average.
Flight from Santo Domingo to Knoxville

When to book flights from Santo Domingo to Knoxville

Are your dates flexible? Find out the best times to travel from Santo Domingo to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Knoxville

  • What is the cheapest flight from Santo Domingo to Knoxville?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Knoxville was $235 for a one-way ticket and $559 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Knoxville?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santo Domingo and on arrival in Knoxville.

  • Which aircraft models fly most regularly from Santo Domingo to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Santo Domingo and Knoxville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Santo Domingo to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Knoxville are Delta and American Airlines. With an average price for the route of $765 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $567 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Santo Domingo to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santo Domingo to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8459 reviews
7.9Comfort
7.8Entertainment
8.1Boarding
8.5Crew
7.2Food
Airline reviews

Seats were comfortable, 8 hours. One flight attendant was not appropriate in his verbal response: "Please, DON'T touch me.", after being tapped near his elbow after being made unaware he skipped serving me & had passed further down the aisle.

10.0 ExcellentVictor, May 2026
MXP - JFK
Read more Delta reviews

Seats were comfortable, 8 hours. One flight attendant was not appropriate in his verbal response: "Please, DON'T touch me.", after being tapped near his elbow after being made unaware he skipped serving me & had passed further down the aisle.

Boarding in Amsterdam is always chaotic. More complicated than needs to be ( boarding pass checked twice, once for general security, then by the airline). The bathrooms on this flight are dirty, and smelly. The food was mediocre at best The crew was decent

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

Round trip flight to Canada and back to the US was smooth and efficient.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

Spanish speaker flight attendants were incredibly rude. A male flight attendant named Allen, grabbed my bag out of the overhead bin and moved it without my permission. When I asked what he was doing, he informed me that the overhead bins were public space? It would be easy to ignore this comment, as you don’t know the whole story, but the flight attendants were militant and rude. Delta, you can do better!

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Everything was fine except the end of the flight. We spent more than an hour circling around Miami due to weather conditions. That was not good.

They lost my bag. ... And I asked them 3 times to 3 different people if my checked bag will maKe it all the way - they all confirmed and at the end it was left at the connection... Bravo

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Delayed due to weather in Dallas (arriving flight arrived late), then boarded the plane only to deboard immediately afterwards, tire needed to be replaced. Flight supposed to depart at 6:15pm but departed at 9:35pm.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

Everything you need to know for your flight from Santo Domingo to Knoxville

Information on your arrival and departure airports