SDQ - TYS

$363 Find Cheap Flights from Santo Domingo to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Knoxville departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Knoxville, as well as popular online travel agencies
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Cheap Flights from Santo Domingo to Knoxville (SDQ-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Knoxville

Sat, Sep 13 - Sat, Sep 20
 Logo
3:47 pm - 11:18 amSDQ-TYS
19h 31m1 stop
 Logo
4:31 pm - 4:00 pmTYS-SDQ
23h 29m1 stop
Sat, Sep 13 - Sat, Sep 20
 Logo
3:47 pm - 6:45 pmSDQ-TYS
26h 58m3 stops
 Logo
4:31 pm - 12:15 pmTYS-SDQ
19h 44m2 stops
Sat, Sep 13 - Sat, Sep 20
 Logo
3:47 pm - 6:45 pmSDQ-TYS
26h 58m3 stops
 Logo
4:31 pm - 7:18 pmTYS-SDQ
26h 47m3 stops
Sat, Sep 20 - Sun, Sep 28
Delta Logo
3:06 pm - 11:44 pmSDQ-TYS
8h 38m1 stop
Delta Logo
5:45 am - 5:59 pmTYS-SDQ
12h 14m2 stops
$510Delta
Find Deal
Sat, Sep 13 - Sat, Sep 20
Delta Logo
6:03 am - 5:03 pmSDQ-TYS
11h 00m2 stops
Delta Logo
11:32 am - 12:36 amTYS-SDQ
13h 04m2 stops
$518Delta
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
12:15 pm - 11:50 pmSDQ-TYS
11h 35m1 stop
American Airlines Logo
7:45 pm - 11:15 amTYS-SDQ
15h 30m2 stops
$530American Airlines
Find Deal
Tue, Aug 19 - Wed, Sep 3
American Airlines Logo
7:05 am - 11:46 pmSDQ-TYS
16h 41m1 stop
American Airlines Logo
6:10 am - 1:35 pmTYS-SDQ
7h 25m1 stop
$541American Airlines
Find Deal
Tue, Aug 19 - Wed, Sep 3
American Airlines Logo
7:05 am - 6:54 pmSDQ-TYS
11h 49m2 stops
American Airlines Logo
6:10 am - 3:20 pmTYS-SDQ
9h 10m1 stop
$545American Airlines
Find Deal
Thu, Aug 14 - Sat, Aug 23
American Airlines Logo
7:05 am - 11:46 pmSDQ-TYS
16h 41m1 stop
American Airlines Logo
7:00 am - 3:25 pmTYS-SDQ
8h 25m1 stop
$578American Airlines
Find Deal
Sat, Nov 22 - Fri, Nov 28
Delta Logo
6:40 am - 6:13 pmSDQ-TYS
12h 33m2 stops
Delta Logo
6:25 am - 2:57 pmTYS-SDQ
7h 32m1 stop
$579Delta
Find Deal
Booking Insights

KAYAK's insights & trends for Santo Domingo to Knoxville flights

Get data-powered insights and trends into flights from Santo Domingo to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to Knoxville?

The average price of all round-trip flights from Santo Domingo to Knoxville clicked on KAYAK for each day over the last 12 months.

For Santo Domingo to Knoxville, Friday is the cheapest day to fly on average and Sunday is the most expensive. Flying from Knoxville back to Santo Domingo, the best deals are generally found on Wednesday, with Monday being the most expensive.

What is the cheapest month to fly from Santo Domingo to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Knoxville is April, where tickets cost $464 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $724 and $696 respectively.

Good to know

Low seasonMarch
Cheapest flight$363
Best time to beat the crowds but there is an average 17% increase in price.
Most popular time to fly with an average 13% increase in price.
Flight from Santo Domingo to Knoxville

When to book flights from Santo Domingo to Knoxville

Are your dates flexible? Find out the best times to travel from Santo Domingo to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Knoxville

  • What is the cheapest flight from Santo Domingo to Knoxville?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Knoxville was $363 for a round-trip ticket.

  • Do I need a passport to fly between Santo Domingo and Knoxville?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santo Domingo and on arrival in Knoxville.

  • Which aircraft models fly most regularly from Santo Domingo to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Santo Domingo and Knoxville, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Santo Domingo to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santo Domingo to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
7.2Comfort
7.5Boarding
8.0Crew
6.9Entertainment
6.5Food
Airline reviews

Very poor delay in dfw was really bad n long

2.0 Mediocredavix, Jul 2025DFW - MKE
Read more American Airlines reviews

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Very clean and comfortable cabin. Amazing Mediterranean salad for lunch before landing. Great range of films to watch. Really quiet and easy to sleep on the flight also. The initial food was a bit weird: odd fried chicken pieces in some weird white gloop, but that would be my lack of cultural knowledge on the grub. Salad more than made up for it at the other end. Staff were super attentive and helpful. Great and easy flight

International baggage recheck process in Philadelphia was a disaster. Waited 1 hour and 45 minutes to receive our bags. Waited 15 minutes to recheck bags, flight notification boards were blank so we asked an AA representative for our connecting gate and we were directed to the wrong terminal and gate. Our connection window was over 3 hours and we made our flight by 5 minutes. We pulled away from the gate and sat on the runway for 1 1/2 hours. 1 of our 4 bags didn’t make it to Phoenix. The mobile app for lost baggage didn’t work, the AA rep had to manually fix.

I miss my flight and they could not rebook me that day because the other flight was full, and for the next day I had to pay a whole new fee again which I think is unprofessional

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

Everything you need to know for your flight from Santo Domingo to Knoxville

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