$165 Find Cheap Flights from Santo Domingo to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to South Carolina departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
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Flights Deals

Best South Carolina Flight Deals from Santo Domingo

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Charleston
Charleston1 stop$374
Myrtle Beach
Myrtle Beach2 stops$541
Charleston
Charleston1 stop$374
Myrtle Beach
Myrtle Beach2 stops$541

Cheap Flights from Santo Domingo to South Carolina

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Santo Domingo to South Carolina

Recommended round-trip deals departing in the coming months from the most popular airlines that fly from Santo Domingo to South Carolina.
Discover the best prices for you by selecting your travel dates on KAYAK.
Frontier Logo
1:05 pm - 9:10 amSDQ-CLT
20h 05m1 stop
Frontier Logo
4:07 pm - 5:25 pmCLT-SDQ
25h 18m1 stop
$300Frontier
Find Deal
Tue, Jul 29 - Tue, Aug 12
Frontier Logo
12:22 pm - 9:09 amSDQ-CLT
20h 47m1 stop
Frontier Logo
4:07 pm - 5:25 pmCLT-SDQ
25h 18m1 stop
$301Frontier
Find Deal
Sat, Jun 7 - Tue, Jul 22
 Logo
12:58 pm - 9:04 amSDQ-CLT
20h 06m1 stop
 Logo
11:52 am - 1:41 amCLT-SDQ
13h 49m1 stop
Tue, Jun 17 - Tue, Aug 19
 Logo
10:19 am - 8:09 amSDQ-CLT
21h 50m1 stop
 Logo
9:32 pm - 9:45 pmCLT-SDQ
24h 13m1 stop
Fri, Jun 13 - Fri, Jun 20
Spirit Airlines Logo
4:05 pm - 10:00 pmSDQ-CLT
5h 55m1 stop
Spirit Airlines Logo
8:50 am - 3:45 pmCLT-SDQ
6h 55m1 stop
$353Spirit Airlines
Find Deal
Wed, May 21 - Mon, May 26
Spirit Airlines Logo
7:30 am - 3:02 pmSDQ-CLT
7h 32m1 stop
Spirit Airlines Logo
3:57 pm - 2:10 amCLT-SDQ
10h 13m1 stop
$365Spirit Airlines
Find Deal
Wed, Oct 22 - Tue, Oct 28
American Airlines Logo
7:10 pm - 10:23 amSDQ-CHS
15h 13m2 stops
American Airlines Logo
8:30 pm - 9:13 amCHS-SDQ
12h 43m2 stops
$502American Airlines
Find Deal
Sat, Jun 7 - Sat, Jun 21
Delta Logo
6:10 am - 9:02 pmSDQ-CLT
14h 52m2 stops
Delta Logo
5:30 am - 5:51 pmCLT-SDQ
12h 21m2 stops
$513Delta
Find Deal
Tue, Sep 9 - Wed, Sep 24
American Airlines Logo
7:00 am - 2:00 pmSDQ-CLT
7h 00m1 stop
American Airlines Logo
5:17 am - 8:55 pmCLT-SDQ
15h 38m1 stop
$521American Airlines
Find Deal
Tue, Jun 10 - Fri, Jul 25
Delta Logo
6:00 am - 6:20 pmSDQ-CLT
12h 20m2 stops
Delta Logo
12:36 pm - 12:57 amCLT-SDQ
12h 21m2 stops
$582Delta
Find Deal
Sat, Jul 5 - Sat, Jul 26
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KAYAK's insights & trends for Santo Domingo to South Carolina flights

Get data-powered insights and trends into flights from Santo Domingo to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to South Carolina?

The average price of all round-trip flights from Santo Domingo to South Carolina clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South Carolina on a Thursday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Santo Domingo to South Carolina. For your return ticket, we recommend flying on a Wednesday and avoiding Mondays for the best deals.


Good to know

Low seasonMay
High seasonDecember
Cheapest flight$165
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly and prices are also 22% lower on average.
Flight from Santo Domingo to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Santo Domingo to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santo Domingo to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santo Domingo to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santo Domingo to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $365 on average. Morning departures are around 38% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $542.

Top airlines flying from Santo Domingo to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7934 reviews
7.9Entertainment
8.5Crew
8.2Boarding
7.9Comfort
7.3Food
Airline reviews

Fine except the person next to me took up her seat had raised the arm divide so she spilled into my seat. because of her size. Fortunately no one was in the seat on my right so I could use part of it.

10.0 ExcellentAnonymous, Apr 2025AMS - ATL
Read more Delta reviews

Fine except the person next to me took up her seat had raised the arm divide so she spilled into my seat. because of her size. Fortunately no one was in the seat on my right so I could use part of it.

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

Delta is a cut above the others in customer service.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

Paid $35 and not able to access the internet at all.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Flight was delayed bc of mechanical issue. New plane had different configuration so some seats had to be switched. They called all passengers who needed new boarding cards. They did not call us so we thought our seats were the same and fine. When we boarded they informed us our receipts had changed and we are now all sitting separate and in the back row. Both my daughters had meltdowns and started to cry and once we got on the flight, we figured out how we could sit closer to each other, but this was very upsetting.

Took off on time and successfully avoided weather that looked to be a problem along the way

Everything you need to know for your flight from Santo Domingo to South Carolina

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