$170 Find Cheap Flights from Santo Domingo to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to South Carolina departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
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Cheap Flights from Santo Domingo to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$332
Columbia
Columbia2 stops$580
Charlotte
Charlotte1 stop$306
Charleston
Charleston1 stop$332
Columbia
Columbia2 stops$580
Charlotte
Charlotte1 stop$306

Book Cheap Santo Domingo to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to South Carolina

Fri, Jan 30 - Mon, Feb 9
Spirit Airlines Logo
4:40 pm - 12:40 amSDQ-CLT
9h 00m1 stop
Spirit Airlines Logo
6:00 am - 3:35 pmCLT-SDQ
8h 35m1 stop
$306Spirit Airlines
Find Deal
Fri, Jan 23 - Sun, Feb 1
Spirit Airlines Logo
4:40 pm - 12:40 amSDQ-CLT
9h 00m1 stop
Spirit Airlines Logo
6:00 am - 3:35 pmCLT-SDQ
8h 35m1 stop
$316Spirit Airlines
Find Deal
Sun, Feb 1 - Sat, Feb 7
Multiple Airlines Logo
4:40 pm - 9:17 pmSDQ-CLT
29h 37m1 stop
Multiple Airlines Logo
7:43 pm - 3:35 pmCLT-SDQ
18h 52m1 stop
$328Multiple Airlines
Find Deal
Mon, Dec 15 - Thu, Jan 1
Delta Logo
6:35 am - 5:06 pmSDQ-CHS
11h 31m1 stop
Delta Logo
7:30 am - 2:32 pmCHS-SDQ
6h 02m1 stop
$332Delta
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Wed, Dec 31 - Mon, Jan 5
Frontier Logo
12:25 pm - 8:29 amSDQ-CLT
21h 04m1 stop
Frontier Logo
8:37 pm - 12:55 pmCLT-SDQ
15h 18m1 stop
$342Frontier
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Sat, Dec 20 - Sat, Jan 3
Frontier Logo
11:16 am - 8:09 pmSDQ-CLT
9h 53m1 stop
Frontier Logo
10:38 pm - 11:10 amCLT-SDQ
11h 32m1 stop
$343Frontier
Find Deal
Fri, May 1 - Mon, May 4
American Airlines Logo
7:55 am - 10:42 pmSDQ-CHS
14h 47m1 stop
American Airlines Logo
11:17 am - 9:50 pmCHS-SDQ
10h 33m1 stop
$344American Airlines
Find Deal
Mon, Dec 15 - Thu, Jan 1
American Airlines Logo
3:06 pm - 12:46 amSDQ-CHS
10h 40m1 stop
American Airlines Logo
8:08 pm - 10:07 amCHS-SDQ
12h 59m2 stops
$356American Airlines
Find Deal
Sun, Dec 21 - Sun, Dec 28
Multiple Airlines Logo
3:59 am - 9:23 pmSDQ-CHS
18h 24m1 stop
Multiple Airlines Logo
10:18 pm - 1:38 pmCHS-SDQ
14h 20m2 stops
$424Multiple Airlines
Find Deal
Sat, Jan 31 - Mon, Feb 2
Delta Logo
2:47 pm - 10:22 pmSDQ-CHS
8h 35m1 stop
Delta Logo
10:31 am - 12:30 amCHS-SDQ
12h 59m2 stops
$429Delta
Find Deal
Booking Insights

KAYAK's insights & trends for Santo Domingo to South Carolina flights

Get data-powered insights and trends into flights from Santo Domingo to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to South Carolina?

The average price of all round-trip flights from Santo Domingo to South Carolina clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South Carolina on a Thursday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Santo Domingo to South Carolina. For your return ticket, we recommend flying on a Wednesday and avoiding Mondays for the best deals.

Good to know

Low seasonMarch
Cheapest flight$170
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Santo Domingo to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Santo Domingo to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santo Domingo to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santo Domingo to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santo Domingo to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $365 on average. Morning departures are around 38% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $542.

Reviews of the top airline flying from Santo Domingo to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8010 reviews
8.1Boarding
8.5Crew
7.9Entertainment
7.3Food
7.9Comfort
Airline reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

4.0 OkayCarl, Dec 2025FLL - LGA
Read more Delta reviews

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

One of the best airlines that I flew on, the flight attendants were very attentive and professional.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

Everything you need to know for your flight from Santo Domingo to South Carolina

Information on your arrival and departure airports