$164 Find Cheap Flights from Santo Domingo to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to South Carolina departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$301
Myrtle Beach
Myrtle Beach2 stops$2,874
Columbia
Columbia2 stops$594
Charlotte
Charlotte1 stop$325
Charleston
Charleston1 stop$301
Myrtle Beach
Myrtle Beach2 stops$2,874
Columbia
Columbia2 stops$594
Charlotte
Charlotte1 stop$325

Book Cheap Santo Domingo to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to South Carolina

Wed, Jan 21 - Sat, Jan 31
Spirit Airlines Logo
4:40 pm - 5:36 pmSDQ-CHS
25h 56m1 stop
Spirit Airlines Logo
6:31 pm - 3:35 pmCHS-SDQ
20h 04m1 stop
$301Spirit Airlines
Find Deal
Mon, Dec 22 - Sun, Jan 11
Multiple Airlines Logo
6:04 pm - 3:56 pmSDQ-CLT
22h 52m1 stop
Multiple Airlines Logo
1:30 pm - 1:42 pmCLT-SDQ
23h 12m1 stop
$325Multiple Airlines
Find Deal
Sun, Dec 21 - Sun, Jan 11
Multiple Airlines Logo
3:59 am - 2:12 pmSDQ-CLT
11h 13m1 stop
Multiple Airlines Logo
1:30 pm - 1:42 pmCLT-SDQ
23h 12m1 stop
$326Multiple Airlines
Find Deal
Sat, Dec 20 - Sat, Jan 3
Frontier Logo
11:16 am - 8:09 pmSDQ-CLT
9h 53m1 stop
Frontier Logo
10:38 pm - 11:10 amCLT-SDQ
11h 32m1 stop
$343Frontier
Find Deal
Fri, May 1 - Mon, May 4
American Airlines Logo
3:25 pm - 10:42 pmSDQ-CHS
7h 17m1 stop
American Airlines Logo
11:17 am - 7:45 pmCHS-SDQ
8h 28m1 stop
$344American Airlines
Find Deal
Fri, Dec 26 - Thu, Jan 8
Frontier Logo
12:35 pm - 8:09 pmSDQ-CLT
8h 34m1 stop
Frontier Logo
8:46 pm - 9:41 amCLT-SDQ
11h 55m1 stop
$345Frontier
Find Deal
Wed, Jan 21 - Sat, Jan 31
American Airlines Logo
6:00 am - 11:07 pmSDQ-CHS
18h 07m2 stops
American Airlines Logo
6:10 am - 5:29 pmCHS-SDQ
10h 19m2 stops
$356American Airlines
Find Deal
Thu, Apr 30 - Mon, May 4
JetBlue Logo
1:40 am - 2:40 pmSDQ-CHS
13h 00m1 stop
JetBlue Logo
9:15 pm - 11:07 amCHS-SDQ
13h 52m1 stop
$533JetBlue
Find Deal
Sat, Dec 6 - Mon, Dec 8
Delta Logo
6:35 am - 5:24 pmSDQ-CHS
11h 49m2 stops
Delta Logo
5:25 am - 7:18 pmCHS-SDQ
12h 53m2 stops
$548Delta
Find Deal
Tue, Feb 17 - Sat, Feb 21
Delta Logo
8:45 pm - 2:21 pmSDQ-CAE
18h 36m2 stops
Delta Logo
5:35 am - 3:30 pmCAE-SDQ
8h 55m1 stop
$594Delta
Find Deal
Booking Insights

KAYAK's insights & trends for Santo Domingo to South Carolina flights

Get data-powered insights and trends into flights from Santo Domingo to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to South Carolina?

The average price of all round-trip flights from Santo Domingo to South Carolina clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South Carolina on a Thursday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Santo Domingo to South Carolina. For your return ticket, we recommend flying on a Wednesday and avoiding Mondays for the best deals.

Find deals

Good to know

Cheapest flight$164
Flight from Santo Domingo to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Santo Domingo to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santo Domingo to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santo Domingo to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santo Domingo to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $365 on average. Morning departures are around 38% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $542.

Reviews of the top airline flying from Santo Domingo to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7997 reviews
8.1Boarding
7.3Food
7.9Comfort
7.9Entertainment
8.5Crew
Airline reviews

It would’ve been nice for all that money to have a more substantial snack for free. I remember once upon a time getting a very nice turkey sandwich with Swiss cheese on whole wheat bread for no charge along with a drink. I guess those days are gone. it’s a little insulting being given a cookie or a bag of baked chips Going forward I’ll just bring my own.

10.0 ExcellentAnonymous, Nov 2025BNA - SLC
Read more Delta reviews

It would’ve been nice for all that money to have a more substantial snack for free. I remember once upon a time getting a very nice turkey sandwich with Swiss cheese on whole wheat bread for no charge along with a drink. I guess those days are gone. it’s a little insulting being given a cookie or a bag of baked chips Going forward I’ll just bring my own.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

the over had ligth did not work'd for the all way

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

DELTA does a terrific job making sure you are well taken care of during the flight, gives you assurance before the flight through numerous email notifications about your upcoming flight & lastly good follow up after the flight making sure your needs were mat. It has been, is & will continue to be my carrier of choice in all my future travels. Good Job DELTA

Everything you need to know for your flight from Santo Domingo to South Carolina

Information on your arrival and departure airports

Santo Domingo (SDQ)