$120 Find Cheap Flights from Santo Domingo to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to South Carolina departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to South Carolina, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$339
Myrtle Beach
Myrtle Beach2 stops$666
Columbia
Columbia2 stops$645
Charlotte
Charlotte1 stop$312
Charleston
Charleston1 stop$339
Myrtle Beach
Myrtle Beach2 stops$666
Columbia
Columbia2 stops$645
Charlotte
Charlotte1 stop$312

Book Cheap Santo Domingo to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to South Carolina

Mon, Dec 22 - Mon, Dec 29
Multiple Airlines Logo
2:53 pm - 8:39 pmSDQ-CLT
6h 46m1 stop
Multiple Airlines Logo
9:43 pm - 11:20 amCLT-SDQ
12h 37m1 stop
$312Multiple Airlines
Find Deal
Mon, Dec 22 - Mon, Dec 29
Multiple Airlines Logo
8:42 pm - 8:00 amSDQ-CLT
36h 18m2 stops
Multiple Airlines Logo
9:43 pm - 11:20 amCLT-SDQ
12h 37m1 stop
$320Multiple Airlines
Find Deal
Sun, Dec 21 - Sun, Dec 28
Frontier Logo
12:35 pm - 8:38 pmSDQ-CLT
9h 03m1 stop
Frontier Logo
9:33 pm - 1:38 pmCLT-SDQ
15h 05m1 stop
$323Frontier
Find Deal
Sun, Dec 21 - Sun, Dec 28
Frontier Logo
8:42 pm - 7:42 pmSDQ-CLT
24h 00m2 stops
Frontier Logo
9:33 pm - 11:20 amCLT-SDQ
12h 47m1 stop
$324Frontier
Find Deal
Thu, Feb 5 - Sat, Feb 7
Delta Logo
3:46 pm - 10:07 pmSDQ-CHS
7h 21m1 stop
Delta Logo
12:00 pm - 12:32 amCHS-SDQ
11h 32m1 stop
$339Delta
Find Deal
Wed, Jan 21 - Sun, Jan 25
Spirit Airlines Logo
6:55 pm - 12:59 amSDQ-CLT
7h 04m1 stop
Spirit Airlines Logo
5:45 am - 5:50 pmCLT-SDQ
11h 05m1 stop
$339Spirit Airlines
Find Deal
Fri, Jan 23 - Sun, Feb 1
Spirit Airlines Logo
8:01 am - 2:48 pmSDQ-CLT
7h 47m1 stop
Spirit Airlines Logo
9:49 am - 5:50 pmCLT-SDQ
7h 01m1 stop
$343Spirit Airlines
Find Deal
Thu, Feb 5 - Sat, Feb 7
Delta Logo
2:33 pm - 10:22 pmSDQ-CHS
8h 49m1 stop
Delta Logo
1:12 pm - 12:32 amCHS-SDQ
10h 20m2 stops
$344Delta
Find Deal
Fri, May 1 - Mon, May 4
American Airlines Logo
3:25 pm - 10:42 pmSDQ-CHS
7h 17m1 stop
American Airlines Logo
11:17 am - 7:45 pmCHS-SDQ
8h 28m1 stop
$358American Airlines
Find Deal
Fri, May 1 - Mon, May 4
American Airlines Logo
5:55 am - 7:03 pmSDQ-CHS
13h 08m2 stops
American Airlines Logo
8:08 pm - 10:50 amCHS-SDQ
14h 42m1 stop
$462American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Santo Domingo to South Carolina flights

Get data-powered insights and trends into flights from Santo Domingo to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santo Domingo to South Carolina?

The average price of all round-trip flights from Santo Domingo to South Carolina clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to South Carolina on a Thursday, as we generally find the cheapest rates on that day for this route. On the other hand, Tuesday is the most expensive day to fly from Santo Domingo to South Carolina. For your return ticket, we recommend flying on a Wednesday and avoiding Mondays for the best deals.

Find deals

Good to know

Low seasonFebruary
Cheapest flight$120
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly and prices are also 14% lower on average.
Flight from Santo Domingo to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Santo Domingo to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Santo Domingo to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Santo Domingo to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Santo Domingo to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally at night, when round-trip flights cost $365 on average. Morning departures are around 38% more expensive than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the morning, which is peak travel time and where the average cost of a ticket is $542.

Reviews of the top airline flying from Santo Domingo to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8001 reviews
7.3Food
7.9Comfort
8.2Boarding
8.5Crew
7.9Entertainment
Airline reviews

I truly love flying with Delta. They have always treated me with the upmost respect

10.0 ExcellentMAYRA, Nov 2025JFK - MIA
Read more Delta reviews

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

DELTA does a terrific job making sure you are well taken care of during the flight, gives you assurance before the flight through numerous email notifications about your upcoming flight & lastly good follow up after the flight making sure your needs were mat. It has been, is & will continue to be my carrier of choice in all my future travels. Good Job DELTA

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

Seats comfortable, service and food very mediocre, staff not very attentive, worse than many other our flights with Delta.

Overall good experience; however, there was one flight attendant who was rather rough compared to everyone else. Everything else was good: entertainment, food. Delta keeps on delivering! Thank you!

Everything you need to know for your flight from Santo Domingo to South Carolina

Information on your arrival and departure airports

Santo Domingo (SDQ)