$603 Find Cheap Flights from Sioux Falls to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Tue, Aug 25 - Thu, Aug 27
United Airlines Logo
6:37 pm - 9:40 am
FSD
-
GRU
13h 03m
1 stop
United Airlines Logo
9:30 pm - 9:52 pm
GRU
-
FSD
26h 22m
2 stops
$872United Airlines
Tue, Aug 25 - Thu, Aug 27
United Airlines Logo
6:37 pm - 9:40 am
FSD
-
GRU
13h 03m
1 stop
United Airlines Logo
9:30 pm - 8:07 pm
GRU
-
FSD
24h 37m
2 stops
$922United Airlines
Thu, Aug 6 - Sun, Aug 16
LATAM Airlines Logo
5:15 am - 6:00 am
FSD
-
SCL
23h 45m
2 stops
LATAM Airlines Logo
4:30 pm - 10:09 pm
SCL
-
FSD
30h 39m
2 stops
$995LATAM Airlines
Thu, Aug 6 - Sun, Aug 16
LATAM Airlines Logo
5:15 am - 6:00 am
FSD
-
SCL
23h 45m
2 stops
LATAM Airlines Logo
8:30 am - 10:09 pm
SCL
-
FSD
38h 39m
3 stops
$1,024LATAM Airlines
Sat, Jun 20 - Sat, Jun 27
LATAM Airlines Logo
5:20 am - 5:40 am
FSD
-
GRU
22h 20m
1 stop
LATAM Airlines Logo
11:40 am - 7:59 pm
GRU
-
FSD
58h 19m
2 stops
$1,026LATAM Airlines
Thu, Aug 6 - Sun, Aug 16
Delta Logo
11:05 am - 7:15 am
FSD
-
SCL
19h 10m
2 stops
Delta Logo
11:25 pm - 7:45 pm
SCL
-
FSD
21h 20m
2 stops
$1,040Delta
Thu, Aug 6 - Sun, Aug 16
Delta Logo
11:05 am - 7:15 am
FSD
-
SCL
19h 10m
2 stops
Delta Logo
10:55 pm - 10:51 pm
SCL
-
FSD
24h 56m
2 stops
$1,090Delta
Thu, Aug 6 - Sun, Aug 16
Delta Logo
5:15 am - 6:00 am
FSD
-
SCL
23h 45m
2 stops
Delta Logo
8:40 pm - 10:09 pm
SCL
-
FSD
26h 29m
1 stop
$1,116Delta
Fri, Jun 5 - Fri, Jun 12
United Airlines Logo
7:40 am - 7:10 am
FSD
-
GRU
21h 30m
2 stops
United Airlines Logo
10:20 pm - 9:43 pm
GRU
-
FSD
25h 23m
1 stop
$1,170United Airlines
Thu, Aug 6 - Sun, Aug 16
LATAM Airlines Logo
5:20 am - 6:00 am
FSD
-
SCL
23h 40m
2 stops
LATAM Airlines Logo
8:30 am - 7:59 pm
SCL
-
FSD
36h 29m
3 stops
$1,182LATAM Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on United Airlines ($872) and LATAM Airlines ($1,024).

Good to know

Cheapest flight$603
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11667 reviews
7.2Comfort
7.5Boarding
6.4Food
6.9Entertainment
7.9Crew
Airline reviews

Flight was delayed an no one cares, or try to help passengers to get the conexión.

2.0 MediocreJavier, May 2026
CLT - LHR
Read more American Airlines reviews

Flight was delayed an no one cares, or try to help passengers to get the conexión.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

The small flights with Valet Luggage has a poor service

Terrible, horrible, disappointing- without telling us they changed planes and moved and separated our seats to opposite sides - said they changed seats putting us together - got to airport to find no, they did not - we sat opposing sides of plane - food overly salty to inedible, never saw stewardess but once - it was terrible

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

The crew was very attentive through out the flight. Seats were comfortable, nice flight bag with pillow and blanket. Food was okay, since it was a overnight flight seemed to go by fast.

The flight attendant on my side of business class seemed like a novice and did not provide good service. Otherwise the flight was good and the entertainment system was very good. No free WiFi.

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Everything you need to know for your flight to South America

Information on your arrival and departure airports