$963 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

jeu., avr. 9 - jeu., avr. 16
American Airlines Logo
6:00 am - 7:05 am
FSD
-
SCL
24h 05m
2 stops
American Airlines Logo
8:35 pm - 11:11 pm
SCL
-
FSD
27h 36m
2 stops
$963American Airlines
jeu., avr. 9 - jeu., avr. 16
Delta Logo
5:20 am - 7:15 am
FSD
-
SCL
24h 55m
1 stop
Delta Logo
11:00 pm - 7:22 pm
SCL
-
FSD
21h 22m
2 stops
$968Delta
jeu., avr. 9 - jeu., avr. 16
LATAM Airlines Logo
5:20 am - 1:25 pm
FSD
-
SCL
31h 05m
3 stops
LATAM Airlines Logo
11:00 pm - 11:40 pm
SCL
-
FSD
25h 40m
2 stops
$993LATAM Airlines
mer., avr. 1 - mer., avr. 8
American Airlines Logo
6:50 am - 7:50 am
FSD
-
SCL
23h 00m
2 stops
American Airlines Logo
8:35 pm - 2:47 pm
SCL
-
FSD
19h 12m
2 stops
$1,038American Airlines
sam., juin 13 - mar., juin 23
Delta Logo
5:25 am - 6:00 am
FSD
-
SCL
23h 35m
2 stops
Delta Logo
10:55 pm - 10:46 pm
SCL
-
FSD
24h 51m
2 stops
$1,040Delta
sam., juin 13 - mar., juin 23
Delta Logo
5:25 am - 7:15 am
FSD
-
SCL
24h 50m
1 stop
Delta Logo
10:55 pm - 10:46 pm
SCL
-
FSD
24h 51m
2 stops
$1,045Delta
mer., avr. 1 - mer., avr. 8
LATAM Airlines Logo
5:20 am - 6:35 am
FSD
-
SCL
23h 15m
2 stops
LATAM Airlines Logo
8:30 am - 10:12 pm
SCL
-
FSD
38h 42m
3 stops
$1,075LATAM Airlines
sam., juin 13 - mar., juin 23
LATAM Airlines Logo
5:25 am - 7:15 am
FSD
-
SCL
24h 50m
1 stop
LATAM Airlines Logo
8:40 pm - 10:11 pm
SCL
-
FSD
26h 31m
1 stop
$1,077LATAM Airlines
mer., avr. 1 - mer., avr. 8
LATAM Airlines Logo
5:20 am - 7:00 am
FSD
-
SCL
23h 40m
2 stops
LATAM Airlines Logo
8:40 pm - 10:12 pm
SCL
-
FSD
26h 32m
1 stop
$1,095LATAM Airlines
mar., mars 31 - mar., avr. 14
American Airlines Logo
12:14 pm - 7:50 am
FSD
-
SCL
17h 36m
2 stops
American Airlines Logo
8:35 pm - 2:47 pm
SCL
-
FSD
19h 12m
2 stops
$1,097American Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on American Airlines ($963) and Delta ($968).

Find deals

Good to know

Cheapest flight$963
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11432 reviews
6.4Food
7.2Comfort
6.9Entertainment
7.9Crew
7.5Boarding
Airline reviews

Dloght delayed by 2.5 hrs . Common theme in my last four american floghts

4.0 OkaySantosh, Mar 2026
SFO - DFW
Read more American Airlines reviews

Dloght delayed by 2.5 hrs . Common theme in my last four american floghts

American continues to decline in their customer service and its beyond disappointing.

Mechanical issue delayed us 2hrs and then once we landed sat on tarmac for 30mins because someone left a vehicle in front of the gaye

The crew was excellent and overall the flight was good. No complaints.

I didn't end up taking this flight. I got up at 4am for a flight that was supposed to board at 6am - at 5:55am you delayed the flight to 10am. The airport is under construction so I switched to a later flight as I wasn't going to sit in the airport for 4 hours. They said the delay was due to the crew needing rest from a flight coming in late the night before - if that was the case then I think you should have delayed the flight much sooner so that passengers wouldn't get up so early and get to the airport to sit and wait.

Never had such a lazy first class attendant. Literally spent 60%+ of the flight playing games on her personal phone making up excuses of why she was unavailable.

The flight attendants and the service is getting worse by the day.

Not to have gotten delayed by 2+ hours for the fourth straight American flight. They're the worst.

Like all of the flights I took to get down to Dallas. They were delayed

Other than nearly three hour delay for maintenance issues, everything went smooth

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Sioux Falls (FSD)