$947 Find Cheap Flights from Sioux Falls to South America - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Wed, Nov 25 - Mon, Nov 30
Delta Logo
5:25 am - 6:00 am
FSD
-
SCL
21h 35m
2 stops
Delta Logo
11:25 pm - 10:12 pm
SCL
-
FSD
25h 47m
2 stops
$947Delta
Wed, Nov 25 - Mon, Nov 30
LATAM Airlines Logo
5:25 am - 7:40 am
FSD
-
SCL
23h 15m
1 stop
LATAM Airlines Logo
12:25 am - 10:12 pm
SCL
-
FSD
24h 47m
2 stops
$973LATAM Airlines
Sat, Nov 7 - Wed, Nov 11
LATAM Airlines Logo
5:25 am - 1:25 pm
FSD
-
SCL
29h 00m
2 stops
LATAM Airlines Logo
4:00 pm - 10:12 pm
SCL
-
FSD
33h 12m
2 stops
$977LATAM Airlines
Wed, Nov 25 - Mon, Nov 30
LATAM Airlines Logo
5:25 am - 1:30 pm
FSD
-
SCL
29h 05m
3 stops
LATAM Airlines Logo
8:30 am - 10:12 pm
SCL
-
FSD
40h 42m
3 stops
$981LATAM Airlines
Sun, Nov 1 - Sat, Nov 14
American Airlines Logo
6:30 am - 9:00 am
FSD
-
SCL
23h 30m
2 stops
American Airlines Logo
10:15 pm - 4:41 pm
SCL
-
FSD
21h 26m
2 stops
$982American Airlines
Wed, Nov 25 - Mon, Nov 30
LATAM Airlines Logo
5:25 am - 5:35 am
FSD
-
SCL
21h 10m
2 stops
LATAM Airlines Logo
12:25 am - 10:12 pm
SCL
-
FSD
24h 47m
2 stops
$983LATAM Airlines
Sat, Aug 1 - Sat, Aug 8
LATAM Airlines Logo
5:20 am - 8:20 pm
FSD
-
GRU
37h 00m
2 stops
LATAM Airlines Logo
11:45 pm - 7:59 pm
GRU
-
FSD
22h 14m
2 stops
$1,008LATAM Airlines
Sun, Nov 1 - Sat, Nov 14
LATAM Airlines Logo
5:25 am - 6:50 am
FSD
-
SCL
46h 25m
2 stops
LATAM Airlines Logo
12:25 am - 10:12 pm
SCL
-
FSD
24h 47m
2 stops
$1,024LATAM Airlines
Tue, Jul 7 - Tue, Aug 4
Multiple Airlines Logo
5:20 am - 8:50 am
FSD
-
GRU
25h 30m
2 stops
Multiple Airlines Logo
12:55 pm - 12:38 pm
GRU
-
FSD
25h 43m
2 stops
$1,035Multiple Airlines
Tue, Jul 7 - Tue, Aug 4
Multiple Airlines Logo
5:20 am - 8:50 am
FSD
-
GRU
25h 30m
2 stops
Multiple Airlines Logo
11:00 pm - 7:59 pm
GRU
-
FSD
22h 59m
2 stops
$1,124Multiple Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Sioux Falls to South America were found on Delta ($947) and LATAM Airlines ($977).

Find deals

Good to know

Cheapest flight$947
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11688 reviews
7.2Comfort
7.9Crew
7.5Boarding
6.4Food
6.8Entertainment
Airline reviews

We had a mechanical delay which made us 90 minutes late (9:30 PM) then land and put into the penalty box because a plane was in our gate? What the hell! We should get priority.Damn American.

6.0 GoodHardin, Jun 2026
ICT - ORD
Read more American Airlines reviews

We had a mechanical delay which made us 90 minutes late (9:30 PM) then land and put into the penalty box because a plane was in our gate? What the hell! We should get priority.Damn American.

Check in for 5am flight at RDU was hampered by American check in counters being seriously understaffed , was told even supervisor called out. Took so long in line for special services check in that we missed our 5am departure even after arriving at 3:30am. Had to be rescheduled to later flight from Charlotte to St Thomas.

Delayed flight due to maintenance and I have had multiple delayed flights due to maintenance in the last month plus

Excellent service. Flight attendance like Jessica,, on our flight, is a reason I wouldn’t mind flying through British Airways again. Jessica,, was very courteous and helpful.

The seats were extremely cramped, with very little legroom or personal space. There was no room left in the overhead bins for a backpack, and the space under the seat in front was so limited that I could barely fit my bag underneath. Overall, the seating arrangement felt very uncomfortable and overcrowded.

Significant delays on my trip to Chicago and my trip back to NY

Terrible boarding and first class experience. Nice staff but overall disorganized, dirty plane.

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

weather delay of almost 2 hours then we landed and our gate wasn't available so we waited another 30 min

Flight had mechanical issues and it was delayed 30 mins - some of us boarded and then had to deplane.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Sioux Falls (FSD)