$764 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Thu, Jan 22 - Mon, Jan 26
LATAM Airlines Logo
5:11 am - 7:40 am
FSD
-
SCL
23h 29m1 stop
LATAM Airlines Logo
10:15 pm - 11:10 pm
SCL
-
FSD
27h 55m2 stops
$764LATAM Airlines
Thu, Jan 22 - Mon, Jan 26
United Airlines Logo
11:22 am - 8:50 am
FSD
-
SCL
18h 28m2 stops
United Airlines Logo
10:45 pm - 8:24 pm
SCL
-
FSD
24h 39m2 stops
$769United Airlines
Tue, Jan 13 - Tue, Feb 17
American Airlines Logo
7:00 am - 8:10 am
FSD
-
GRU
22h 10m1 stop
American Airlines Logo
11:00 pm - 12:33 pm
GRU
-
FSD
16h 33m1 stop
$1,165American Airlines
Tue, Jan 13 - Tue, Feb 17
American Airlines Logo
12:26 pm - 8:50 am
FSD
-
GRU
17h 24m2 stops
American Airlines Logo
10:35 pm - 4:47 pm
GRU
-
FSD
21h 12m2 stops
$1,170American Airlines
Tue, Jan 13 - Tue, Feb 17
United Airlines Logo
7:30 am - 7:15 am
FSD
-
GRU
20h 45m1 stop
United Airlines Logo
9:45 pm - 5:21 pm
GRU
-
FSD
22h 36m1 stop
$1,205United Airlines
Tue, Jan 13 - Mon, Feb 16
American Airlines Logo
7:00 am - 6:20 am
FSD
-
GRU
20h 20m2 stops
American Airlines Logo
12:15 am - 4:47 pm
GRU
-
FSD
19h 32m2 stops
$1,210American Airlines
Wed, Jun 10 - Tue, Jun 16
LATAM Airlines Logo
5:25 am - 5:30 am
FSD
-
GRU
22h 05m2 stops
LATAM Airlines Logo
2:45 pm - 10:11 pm
GRU
-
FSD
33h 26m2 stops
$1,261LATAM Airlines
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
7:40 am - 7:15 am
FSD
-
GRU
20h 35m1 stop
United Airlines Logo
10:15 pm - 10:46 am
GRU
-
FSD
14h 31m1 stop
$1,325United Airlines
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
11:21 am - 8:55 am
FSD
-
GRU
18h 34m2 stops
United Airlines Logo
9:30 pm - 8:44 pm
GRU
-
FSD
25h 14m2 stops
$1,330United Airlines
Wed, Jun 10 - Tue, Jun 16
American Airlines Logo
7:05 am - 7:15 am
FSD
-
GRU
22h 10m1 stop
American Airlines Logo
10:00 pm - 4:45 pm
GRU
-
FSD
20h 45m1 stop
$1,850American Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Sioux Falls and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Sioux Falls to South America.

There is just one airline that flies from Sioux Falls to South America direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is to Lima (LIM) and costs $638.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on LATAM Airlines ($764) and United Airlines ($769).

Find deals

Good to know

Low seasonSeptember
Cheapest flight$764
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the afternoon, when round-trip flights cost $930 on average. Morning departures are around 33% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $1,450.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11057 reviews
7.2Comfort
7.5Boarding
6.5Food
8.0Crew
6.9Entertainment
Airline reviews

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

8.0 ExcellentAustin, Dec 2025
ECP - CLT
Read more American Airlines reviews

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

Flight was delayed 17 hours due to aircraft issues. American did provide hotel, transportation and meals, 3 hours past boarding time, but it took us another hour to get the vouchers.

Flight was on time is the only good thing. Person loading the plane called 1-6 to board at the same time, made it chaotic. Plane was too small for even putting backpacks in overhead. Seat for normal sized people were too small. The WIFI didn't work. When we landed had to wait because not enough ground crew.

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

Flight was late and boarding was confusing because gate changed and I didn’t get a notification

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Not comparable to Qatar Airways services on flights to Doha. Flight attendants provided basic services; I was never recognized by name or as an Executive Platinum member. Restrooms were not kept clean during the flight.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Sioux Falls (FSD)