$690 Find Cheap Flights from Sioux Falls to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Thu, Sep 10 - Thu, Sep 17
United Airlines Logo
7:47 am - 9:40 am
FSD
-
GRU
23h 53m
1 stop
United Airlines Logo
10:20 pm - 10:37 am
GRU
-
FSD
14h 17m
1 stop
$968United Airlines
Thu, Sep 10 - Thu, Sep 17
Delta Logo
5:30 am - 5:05 am
FSD
-
GRU
21h 35m
2 stops
Delta Logo
10:45 pm - 7:47 pm
GRU
-
FSD
23h 02m
2 stops
$972Delta
Wed, Jan 20 - Wed, Jan 27
Delta Logo
5:25 am - 5:20 am
FSD
-
SCL
20h 55m
2 stops
Delta Logo
12:48 am - 10:12 pm
SCL
-
FSD
24h 24m
2 stops
$995Delta
Tue, Jan 26 - Mon, Feb 1
LATAM Airlines Logo
5:25 am - 5:20 am
FSD
-
SCL
20h 55m
2 stops
LATAM Airlines Logo
5:00 pm - 10:12 pm
SCL
-
FSD
32h 12m
2 stops
$997LATAM Airlines
Tue, Jan 12 - Wed, Jan 27
United Airlines Logo
7:40 am - 8:50 am
FSD
-
SCL
22h 10m
2 stops
United Airlines Logo
10:45 pm - 4:06 pm
SCL
-
FSD
20h 21m
2 stops
$1,000United Airlines
Sat, Jan 23 - Wed, Jun 2
Delta Logo
8:15 am - 9:55 am
FSD
-
GRU
22h 40m
2 stops
Delta Logo
10:45 pm - 10:12 pm
GRU
-
FSD
25h 27m
2 stops
$1,002Delta
Sat, Jan 23 - Wed, Jun 2
Delta Logo
10:58 am - 9:55 am
FSD
-
GRU
19h 57m
2 stops
Delta Logo
10:50 pm - 10:12 pm
GRU
-
FSD
25h 22m
1 stop
$1,008Delta
Sun, Jan 24 - Mon, Feb 1
Delta Logo
4:09 pm - 6:40 am
FSD
-
SCL
35h 31m
2 stops
Delta Logo
11:10 pm - 10:51 pm
SCL
-
FSD
26h 41m
2 stops
$1,017Delta
Sun, Jan 17 - Wed, Jan 27
United Airlines Logo
9:14 am - 8:50 am
FSD
-
SCL
44h 36m
2 stops
United Airlines Logo
10:45 pm - 4:06 pm
SCL
-
FSD
20h 21m
2 stops
$1,018United Airlines
Sat, Jan 23 - Sun, Jan 31
LATAM Airlines Logo
5:25 am - 6:40 am
FSD
-
SCL
22h 15m
1 stop
LATAM Airlines Logo
5:00 pm - 10:12 pm
SCL
-
FSD
32h 12m
2 stops
$1,021LATAM Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Sioux Falls to South America were found on United Airlines ($968) and Delta ($972).

Good to know

Cheapest flight

$690
Flight from Sioux Falls to Sao Paulo

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11845 reviews
7.2Comfort
6.8Entertainment
7.5Boarding
7.9Crew
6.4Food
Airline reviews

Everything was done like clockwork and I find no fault with the airline.

10.0 ExcellentGlendon, Jul 2026
MIA - PHX
Read more American Airlines reviews

Everything was done like clockwork and I find no fault with the airline.

This flight 1810 on 7/30 from EWR to DFW got 4 hours delay. this round trip experience is bad, my AA flight 618 from DFW to EWR on 7/28 was redirected to PIT and totally delayed about 9 hours due to mixed of weather and AA IT outage and then on the way back delayed for 4 hours. Lucky, i changed my flight to UA on the way back. i don't like AA anymore. i will consider other airline options in the future.

Bad experience going to DFW with an IT outage then bad on the way back with a nearly 5 hour delay that’s started as maintenance then caused us to wait further due to weather - which would not have happened if we had left on time.

IT issues created a mess had you change my flight and your system never changed it

Horrible experience flying with American. Flight was delayed due to inbound flight delay. Fine, it happens. Then, we were delayed an additional almost 30 minutes due to the paperwork for departure having a "clerical error." Then, upon landing at the destination airport we were stuck on the plane for an HOUR after we landed and pulled up to the gate because apparently there was another plane. An hour waiting for the gate 12:30 AM when the flight has already been delayed due to operational error feels like a complete failure of the ability to do the one thing they need to do apart from actually have the plane takeoff and land. Very disappointing.

It was a 3 hour flight from Dallas to Missoula. The aircraft did not have power plugs, internet or in-flight entertainment. When boarding, one flight attendant was "somewhere in the airport" so delayed the boarding process (not coming from another flight) although we did take off on time and landed early. In flight there was little to no service - we got the standard beverage but no real connection with the crew which feels unusual for a 3 hour flight. A passenger needed help stowing her bag and got no assistance, and actually some passive aggressive comments from the flight attendants about "she needs to remove the extender" and "she'll have to find a place for it". I have seen others be helpful and put a bag in the closet, or support assistance as the boarding door was already closed. Just not a great experience considering the cost of my round trip ticket {$1000}.

Disorganized boarding. Mandatory to gate check bags. Curt flight staff. No space for cabin bag, even when I was in first class.

On time departure & early arrival. Made a long day much better.

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Everything you need to know for your flight to South America

Information on your arrival and departure airports