$572 Find Cheap Flights from Sioux Falls to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Wed, Aug 26 - Mon, Aug 31
Delta Logo
5:30 am - 5:55 am
FSD
-
SCL
23h 25m
2 stops
Delta Logo
11:05 pm - 7:59 pm
SCL
-
FSD
21h 54m
2 stops
$997Delta
Thu, Aug 27 - Mon, Aug 31
Multiple Airlines Logo
5:30 am - 1:25 pm
FSD
-
SCL
30h 55m
3 stops
Multiple Airlines Logo
11:00 pm - 11:22 pm
SCL
-
FSD
25h 22m
2 stops
$1,002Multiple Airlines
Wed, Aug 26 - Tue, Sep 1
LATAM Airlines Logo
5:30 am - 5:55 am
FSD
-
SCL
23h 25m
2 stops
LATAM Airlines Logo
8:40 pm - 7:59 pm
SCL
-
FSD
24h 19m
1 stop
$1,008LATAM Airlines
Wed, Aug 26 - Mon, Aug 31
LATAM Airlines Logo
5:30 am - 7:15 am
FSD
-
SCL
24h 45m
1 stop
LATAM Airlines Logo
8:40 pm - 7:59 pm
SCL
-
FSD
24h 19m
1 stop
$1,019LATAM Airlines
Sat, Sep 5 - Sat, Sep 12
LATAM Airlines Logo
5:30 am - 8:00 pm
FSD
-
GRU
60h 30m
2 stops
LATAM Airlines Logo
9:30 pm - 7:47 pm
GRU
-
FSD
48h 17m
2 stops
$1,023LATAM Airlines
Fri, Aug 28 - Tue, Sep 1
Delta Logo
5:30 am - 5:55 am
FSD
-
SCL
23h 25m
2 stops
Delta Logo
7:55 pm - 7:59 pm
SCL
-
FSD
25h 04m
2 stops
$1,027Delta
Sat, Aug 22 - Sat, Aug 29
American Airlines Logo
7:30 am - 9:00 am
FSD
-
GRU
23h 30m
1 stop
American Airlines Logo
11:15 pm - 10:07 pm
GRU
-
FSD
24h 52m
2 stops
$1,059American Airlines
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
7:30 am - 9:00 am
FSD
-
GRU
23h 30m
1 stop
American Airlines Logo
11:15 pm - 9:44 pm
GRU
-
FSD
24h 29m
2 stops
$1,217American Airlines
Tue, Sep 1 - Sat, Sep 5
United Airlines Logo
7:47 am - 9:40 am
FSD
-
GRU
23h 53m
1 stop
United Airlines Logo
10:20 pm - 10:29 am
GRU
-
FSD
14h 09m
1 stop
$1,438United Airlines
Tue, Sep 1 - Sat, Sep 5
United Airlines Logo
6:39 pm - 9:40 am
FSD
-
GRU
13h 01m
1 stop
United Airlines Logo
10:20 pm - 10:29 am
GRU
-
FSD
14h 09m
1 stop
$3,141United Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Sioux Falls to South America were found on Delta ($997) and LATAM Airlines ($1,029).

Good to know

Cheapest flight

$572
Flight from Sioux Falls to Sao Paulo

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11847 reviews
7.9Crew
6.8Entertainment
6.4Food
7.5Boarding
7.2Comfort
Airline reviews

Patrons with larger bags were asked to check the bags when boarding. Seems like the most effective, and least costly way, way to successfully use the cramped space.

10.0 ExcellentSergio, Jul 2026
DCA - CLE
Read more American Airlines reviews

Patrons with larger bags were asked to check the bags when boarding. Seems like the most effective, and least costly way, way to successfully use the cramped space.

Like all planes recently, entertainment is achieved by giving the patron free WiFi and letting them stream shows via the screen on a phone or tablet.

Worst communication. Delayed boarding for two hours without a single announcement until hour 1 had passed - on time status showing until our flight was supposed to takeoff and the crew had already walked away. No one was boarding. Disgusting part of DFW overcrowded with no AC on a 97 degree day. Then the first app update is that we’d take off in 15 mins… but again no one had boarded a full flight. No announcement in the terminal so everyone is just crowded around a disgusting place with no info for over an hour which turned into two. This was an overfill flight and a disgrace to passenger decency all while likely just trying to fix their own issue of overbooking. The worst airline at the worst airport.

My seat had a worn out cushion, which made it a bit uncomfortable. Other than that, the flight was excellent.

The flight was delayed almost three hours. I understand delays happen from time to time, but this flight was delayed no less than 10 times. I wish the amount of time of the delay was more accurate, versus delaying in 10 or 20 minute increments many, many times.

I thought American Airlines did well considering the adverse weather situation over July 21 and 22. I especially appreciated the consideration given to me when I got stuck in Miami on my way to Boston from Charleston, West Virginia. Thank you for providing a voucher for an overnight stay. Though it was only a few hours of sleep, it was very helpful. I was able to reschedule my medical appointment and got back to the Boston area on the 1st flight out of Miami as a standby passenger. It was very helpful that I was given number one priority on the standby list.

I’ve been on 8 flights with American Airlines in the last 2 months and 4 have been delayed.

The flight was ok, i understand Houston-Dallas is a short distance. The plane is really small: no TV, no snacks, but other than that, all was good. We had a bid delay but luckily it did not affect my connection

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Everything you need to know for your flight to South America

Information on your arrival and departure airports