$665 Find Cheap Flights from Sioux Falls to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Mon, Nov 9 - Wed, Nov 11
United Airlines Logo
6:00 am - 7:15 am
FSD
-
GRU
22h 15m
1 stop
United Airlines Logo
9:30 pm - 5:34 pm
GRU
-
FSD
23h 04m
1 stop
$917United Airlines
Mon, Nov 9 - Wed, Nov 11
United Airlines Logo
9:14 am - 7:15 am
FSD
-
GRU
19h 01m
2 stops
United Airlines Logo
9:45 pm - 5:34 pm
GRU
-
FSD
22h 49m
2 stops
$922United Airlines
Mon, Nov 9 - Wed, Nov 11
United Airlines Logo
9:14 am - 7:15 am
FSD
-
GRU
19h 01m
2 stops
United Airlines Logo
10:25 pm - 5:34 pm
GRU
-
FSD
22h 09m
2 stops
$972United Airlines
Mon, Nov 9 - Wed, Nov 11
United Airlines Logo
9:14 am - 7:15 am
FSD
-
GRU
19h 01m
2 stops
United Airlines Logo
9:45 pm - 2:35 pm
GRU
-
FSD
19h 50m
2 stops
$1,012United Airlines
Thu, Aug 6 - Sun, Aug 16
Delta Logo
11:05 am - 7:15 am
FSD
-
SCL
19h 10m
2 stops
Delta Logo
8:40 pm - 7:45 pm
SCL
-
FSD
24h 05m
2 stops
$1,040Delta
Thu, Aug 6 - Sun, Aug 16
Delta Logo
11:05 am - 7:15 am
FSD
-
SCL
19h 10m
2 stops
Delta Logo
10:55 pm - 10:51 pm
SCL
-
FSD
24h 56m
2 stops
$1,090Delta
Thu, Aug 6 - Sun, Aug 16
LATAM Airlines Logo
5:20 am - 9:15 pm
FSD
-
SCL
38h 55m
3 stops
LATAM Airlines Logo
11:05 pm - 7:59 pm
SCL
-
FSD
21h 54m
2 stops
$1,184LATAM Airlines
Thu, Aug 6 - Sun, Aug 16
Delta Logo
11:05 am - 7:15 am
FSD
-
SCL
19h 10m
2 stops
Delta Logo
8:40 pm - 7:59 pm
SCL
-
FSD
24h 19m
1 stop
$1,230Delta
Thu, Aug 6 - Sun, Aug 16
LATAM Airlines Logo
5:20 am - 6:00 am
FSD
-
SCL
23h 40m
2 stops
LATAM Airlines Logo
8:30 am - 7:59 pm
SCL
-
FSD
36h 29m
3 stops
$1,232LATAM Airlines
Thu, Aug 6 - Sun, Aug 16
LATAM Airlines Logo
5:20 am - 9:15 pm
FSD
-
SCL
38h 55m
3 stops
LATAM Airlines Logo
8:30 am - 7:59 pm
SCL
-
FSD
36h 29m
3 stops
$1,289LATAM Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on United Airlines ($917) and Delta ($1,040).

Find deals

Good to know

Cheapest flight$665
Flight from Sioux Falls to Sao Paulo

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11664 reviews
7.9Crew
7.2Comfort
7.5Boarding
6.4Food
6.9Entertainment
Airline reviews

Seat comfort was poor (no lumbar or lower back support).

8.0 ExcellentAnonymous, May 2026
PIT - DFW
Read more American Airlines reviews

Seat comfort was poor (no lumbar or lower back support).

The airplane seats were spacious and comfortable, and the flight attendants were friendly and attentive. The food was delicious like never before. The blankets and toiletries were thoughtfully provided. The captain's navigation was steady and reliable. In short, having flown with Starlux, I won't consider any other airline next time.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Flight was delayed an no one cares, or try to help passengers to get the conexión.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Sioux Falls (FSD)