$1,155 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Sat, May 16 - Sat, May 23
American Airlines Logo
6:00 am - 7:05 am
FSD
-
SCL
24h 05m
2 stops
American Airlines Logo
9:00 pm - 4:16 pm
SCL
-
FSD
20h 16m
2 stops
$1,155American Airlines
Sat, May 16 - Sat, May 23
LATAM Airlines Logo
5:20 am - 6:00 am
FSD
-
SCL
23h 40m
2 stops
LATAM Airlines Logo
8:40 pm - 7:49 pm
SCL
-
FSD
24h 09m
1 stop
$1,207LATAM Airlines
Thu, Apr 30 - Mon, May 4
LATAM Airlines Logo
5:25 am - 1:35 pm
FSD
-
SCL
31h 10m
2 stops
LATAM Airlines Logo
11:05 pm - 11:40 pm
SCL
-
FSD
25h 35m
2 stops
$1,245LATAM Airlines
Thu, Apr 30 - Mon, May 4
LATAM Airlines Logo
5:25 am - 6:55 am
FSD
-
SCL
24h 30m
2 stops
LATAM Airlines Logo
8:30 am - 11:40 pm
SCL
-
FSD
40h 10m
3 stops
$1,250LATAM Airlines
Sat, May 16 - Sat, May 23
LATAM Airlines Logo
5:20 am - 7:15 am
FSD
-
SCL
24h 55m
1 stop
LATAM Airlines Logo
8:40 pm - 7:49 pm
SCL
-
FSD
24h 09m
1 stop
$1,251LATAM Airlines
Mon, Aug 10 - Thu, Aug 13
United Airlines Logo
7:40 am - 9:40 am
FSD
-
GRU
24h 00m
1 stop
United Airlines Logo
9:50 pm - 6:15 pm
GRU
-
FSD
22h 25m
2 stops
$1,267United Airlines
Thu, Apr 30 - Mon, May 4
LATAM Airlines Logo
5:25 am - 1:25 pm
FSD
-
SCL
31h 00m
3 stops
LATAM Airlines Logo
11:00 pm - 11:40 pm
SCL
-
FSD
25h 40m
2 stops
$1,284LATAM Airlines
Mon, Aug 10 - Thu, Aug 13
United Airlines Logo
7:40 am - 9:40 am
FSD
-
GRU
24h 00m
1 stop
United Airlines Logo
10:20 pm - 6:02 pm
GRU
-
FSD
21h 42m
1 stop
$1,336United Airlines
Mon, Aug 10 - Thu, Aug 13
United Airlines Logo
9:30 am - 9:30 am
FSD
-
GRU
22h 00m
2 stops
United Airlines Logo
10:20 pm - 6:02 pm
GRU
-
FSD
21h 42m
1 stop
$1,340United Airlines
Mon, Aug 10 - Thu, Aug 13
LATAM Airlines Logo
5:25 am - 5:30 am
FSD
-
GRU
22h 05m
2 stops
LATAM Airlines Logo
11:45 pm - 10:09 pm
GRU
-
FSD
24h 24m
2 stops
$1,376LATAM Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on LATAM Airlines ($1,245) and United Airlines ($1,267).

Find deals

Good to know

Cheapest flight$1,155
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11556 reviews
6.4Food
6.9Entertainment
7.2Comfort
7.9Crew
7.5Boarding
Airline reviews

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

4.0 OkayJohn, Apr 2026
DCA - LAX
Read more American Airlines reviews

Going non stop to lax like I paid for. Not stopping in MCI for gas. Too long of delays

Human interaction. Thought there would be more service-even a smile would have been nice.

It was canceled at the last minute. While I was literally at the airport. Messed my entire trip up.

Seat was VERY uncomfortable. Flight was delayed and then boarded slowly. The crew was super helpful with boarding and supporting maximizing the luggage in the overhead.

Crew at the gate was very crabby and not at all polite. The plane was very hot the entire flight. And the seat cushion was very worn out.

Incoming flight was delayed, delaying boarding. It then took 30 mins to take off. Took 20 mins to get to a gate because they changed the gate last minute, crew weren’t ready so there was no one staffed to work the jet bridge. Boarding was so disorganized as is usual with American because everyone just stands around the gate regardless of boarding group.

I cancelled my ticket less than 24 hours deadline but I didn’t get refunded.

Early morning flight and no food in First Class except a "salmon" box. No thank you. Was informed before take off by Captain that the plane was not serviced before we boarded in Phoenix. How does that happen? Need more frequent additions/turn over on the Entertainment. Thanks

Moved to earlier flight which unexpectedly had maintenance issues initially indicated as quick fix to ultimately plane changes. Moved back to original flight, also delayed. In all cases customer updates and communication very unclear, no updates on drivers for delays.

Flight was delayed. No urgency by American Airlines team to assist those with connecting flights. It was basically you are on your own to run through the terminals to try and make your connection. Thanks, Mary

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Sioux Falls (FSD)