$303 Find Cheap Flights from Sioux Falls to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Wed, Aug 12 - Tue, Aug 18
American Airlines Logo
6:24 am - 7:05 am
FSD
-
SCL
23h 41m
2 stops
American Airlines Logo
8:50 pm - 12:17 pm
SCL
-
FSD
16h 27m
2 stops
$952American Airlines
Wed, Aug 12 - Tue, Aug 18
Delta Logo
5:30 am - 5:55 am
FSD
-
SCL
23h 25m
2 stops
Delta Logo
8:40 pm - 7:59 pm
SCL
-
FSD
24h 19m
1 stop
$953Delta
Wed, Aug 12 - Tue, Aug 18
Delta Logo
5:30 am - 7:15 am
FSD
-
SCL
24h 45m
1 stop
Delta Logo
8:40 pm - 7:59 pm
SCL
-
FSD
24h 19m
1 stop
$958Delta
Wed, Aug 12 - Tue, Aug 18
LATAM Airlines Logo
5:30 am - 6:55 am
FSD
-
SCL
24h 25m
2 stops
LATAM Airlines Logo
8:30 am - 7:59 pm
SCL
-
FSD
36h 29m
3 stops
$976LATAM Airlines
Wed, Aug 12 - Tue, Aug 18
LATAM Airlines Logo
5:30 am - 6:55 am
FSD
-
SCL
48h 25m
2 stops
LATAM Airlines Logo
8:30 am - 7:59 pm
SCL
-
FSD
36h 29m
3 stops
$994LATAM Airlines
Wed, Aug 12 - Tue, Aug 18
LATAM Airlines Logo
5:30 am - 6:55 am
FSD
-
SCL
48h 25m
2 stops
LATAM Airlines Logo
8:40 pm - 7:59 pm
SCL
-
FSD
24h 19m
1 stop
$999LATAM Airlines
Wed, Aug 12 - Tue, Aug 18
LATAM Airlines Logo
5:30 am - 1:25 pm
FSD
-
SCL
54h 55m
3 stops
LATAM Airlines Logo
8:30 am - 7:59 pm
SCL
-
FSD
36h 29m
3 stops
$1,001LATAM Airlines
Fri, Jul 17 - Tue, Aug 18
Delta Logo
5:20 am - 7:15 am
FSD
-
SCL
24h 55m
1 stop
Delta Logo
10:55 pm - 10:51 pm
SCL
-
FSD
24h 56m
2 stops
$1,120Delta
Fri, Dec 18 - Fri, Mar 12
GOL Logo
1:16 pm - 8:30 am
FSD
-
GRU
16h 14m
1 stop
GOL Logo
10:45 pm - 4:49 pm
GRU
-
FSD
21h 04m
1 stop
$1,738GOL
Fri, Dec 18 - Fri, Mar 12
GOL Logo
1:16 pm - 8:30 am
FSD
-
GRU
16h 14m
1 stop
GOL Logo
11:50 pm - 4:49 pm
GRU
-
FSD
19h 59m
2 stops
$1,742GOL
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Sioux Falls to South America were found on Delta ($953) and LATAM Airlines ($1,349).

Good to know

Cheapest flight$303
Flight from Sioux Falls to Sao Paulo

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11767 reviews
7.9Crew
6.8Entertainment
7.2Comfort
7.5Boarding
6.4Food
Airline reviews

The hosts were very friendly and accommodating. The food was welcomed and very decent. I would recommend!

10.0 ExcellentAnonymous, Jul 2026
DFW - ATH
Read more American Airlines reviews

The hosts were very friendly and accommodating. The food was welcomed and very decent. I would recommend!

I found the seats ergonomically uncomfortable forcing the body to seat slightly hunched. For a short flight I worked on adjustments but for a longer flight, it would be difficult.

The seat was not even cleaned. It has full of cookie crums probably from last flight's passenger. Its basic expectation that, seats are clean.

Crew was great! Food sub-bar, tepid & flavorless. No snack options on trans-atlantic flight. Premium Economy seats ok, leg rest wouldn’t stay in place.

The planes can use an actual cleaning. The armrest and seats do not appear to be cleaned on this one and most other planes.

The flight attendant was very polite and attentive. The food was good.

For some unknown reason, my checked bag didn't arrive at the same time. I got to my destination about 30 minutes late (5pm) and my bag was delivered to my hotel at 2:06am.... in the past 4 flights with AA, they been delayed and I've missed connections and my bags. Poor service.

Flight was delayed…once landed at ORD, no gates were available so made us wait for 56 minutes after we landed to let us out of the aircraft!

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Everything you need to know for your flight to South America

Information on your arrival and departure airports