$545 Find Cheap Flights from Sioux Falls to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Sat, Dec 13 - Mon, Jan 12
United Airlines Logo
8:00 am - 8:50 amFSD-SCL
21h 50m2 stops
United Airlines Logo
10:45 pm - 8:39 pmSCL-FSD
24h 54m2 stops
$864United Airlines
Find Deal
Sat, Dec 13 - Tue, Jan 13
United Airlines Logo
5:21 pm - 8:50 amFSD-SCL
36h 29m2 stops
United Airlines Logo
10:45 pm - 5:18 pmSCL-FSD
21h 33m2 stops
$880United Airlines
Find Deal
Sat, Dec 13 - Tue, Jan 13
Multiple Airlines Logo
5:05 am - 9:35 pmFSD-SCL
61h 30m3 stops
Multiple Airlines Logo
9:10 am - 8:39 pmSCL-FSD
38h 29m2 stops
$961Multiple Airlines
Find Deal
Sat, Dec 13 - Mon, Jan 12
United Airlines Logo
8:00 am - 8:50 amFSD-SCL
21h 50m3 stops
United Airlines Logo
10:45 pm - 8:39 pmSCL-FSD
24h 54m2 stops
$994United Airlines
Find Deal
Sat, Dec 13 - Tue, Jan 13
LATAM Airlines Logo
5:05 am - 7:40 amFSD-SCL
23h 35m1 stop
LATAM Airlines Logo
6:40 am - 11:14 pmSCL-FSD
19h 34m2 stops
$1,035LATAM Airlines
Find Deal
Tue, Jan 13 - Tue, Feb 17
LATAM Airlines Logo
5:08 am - 6:15 amFSD-GRU
22h 07m2 stops
LATAM Airlines Logo
10:55 pm - 11:12 pmGRU-FSD
27h 17m2 stops
$1,087LATAM Airlines
Find Deal
Sat, Apr 25 - Wed, Apr 29
Delta Logo
5:25 am - 8:00 pmFSD-GRU
36h 35m2 stops
Delta Logo
10:45 pm - 3:28 pmGRU-FSD
18h 43m2 stops
$1,145Delta
Find Deal
Tue, Jan 13 - Mon, Feb 16
American Airlines Logo
12:26 pm - 8:50 amFSD-GRU
17h 24m2 stops
American Airlines Logo
12:15 am - 4:43 pmGRU-FSD
19h 28m2 stops
$1,150American Airlines
Find Deal
Mon, Dec 8 - Wed, Dec 10
American Airlines Logo
1:09 pm - 7:45 amFSD-SCL
15h 36m1 stop
American Airlines Logo
11:15 pm - 12:22 pmSCL-FSD
16h 07m1 stop
$1,284American Airlines
Find Deal
Sat, Dec 13 - Mon, Jan 12
Multiple Airlines Logo
8:00 am - 5:35 amFSD-SCL
18h 35m2 stops
Multiple Airlines Logo
11:10 pm - 11:14 pmSCL-FSD
27h 04m1 stop
$1,343Multiple Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Sioux Falls to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Sioux Falls to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Sioux Falls to South America is September, when tickets cost $638 (return) on average. On the other hand, the most expensive months are May and August, when the average cost of round-trip tickets is $1,763 and $1,219 respectively.

Good to know

Low seasonJune
Cheapest flight$545
Best time to beat the crowds but there is an average 13% increase in price.
Most popular time to fly and prices are also 8% lower on average.
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the afternoon, when round-trip flights cost $930 on average. Morning departures are around 33% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $1,450.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11042 reviews
7.2Comfort
6.9Entertainment
7.5Boarding
8.0Crew
6.4Food
Airline reviews

We loved the steward on the plane. He made the night enjoyable

10.0 Excellentchloe, Nov 2025ORD - ATW
Read more American Airlines reviews

We loved the steward on the plane. He made the night enjoyable

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

Flight delay was communicated before leaving for airport which caused it to be a non-event. Great flight and crew!

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Everything you need to know for your flight to South America

Information on your arrival and departure airports