$788 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Sioux Falls to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago1 stop$788
Santiago
Santiago1 stop$788

Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Mon, Dec 8 - Thu, Dec 11
Delta Logo
5:25 am - 7:00 amFSD-SCL
22h 35m1 stop
Delta Logo
11:15 pm - 12:31 pmSCL-FSD
16h 16m2 stops
$788Delta
Find Deal
Mon, Dec 8 - Thu, Dec 11
United Airlines Logo
8:00 am - 8:50 amFSD-SCL
21h 50m3 stops
United Airlines Logo
10:45 pm - 2:40 pmSCL-FSD
18h 55m2 stops
$838United Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 11
American Airlines Logo
1:28 pm - 7:50 amFSD-SCL
15h 22m1 stop
American Airlines Logo
11:15 pm - 12:22 pmSCL-FSD
16h 07m1 stop
$944American Airlines
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Tue, Jan 13 - Tue, Feb 17
United Airlines Logo
11:20 am - 7:15 amFSD-GRU
16h 55m1 stop
United Airlines Logo
9:45 pm - 2:35 pmGRU-FSD
19h 50m1 stop
$1,040United Airlines
Find Deal
Sat, Oct 18 - Mon, Nov 10
United Airlines Logo
9:30 am - 9:30 amFSD-GRU
22h 00m2 stops
United Airlines Logo
10:15 pm - 12:31 pmGRU-FSD
17h 16m2 stops
$1,044United Airlines
Find Deal
Tue, Jan 13 - Mon, Feb 16
American Airlines Logo
12:27 pm - 6:20 amFSD-GRU
14h 53m2 stops
American Airlines Logo
12:15 am - 2:50 pmGRU-FSD
17h 35m2 stops
$1,069American Airlines
Find Deal
Sat, Oct 18 - Mon, Nov 10
American Airlines Logo
1:27 pm - 7:15 amFSD-GRU
15h 48m1 stop
American Airlines Logo
11:00 pm - 4:39 pmGRU-FSD
20h 39m1 stop
$1,180American Airlines
Find Deal
Sat, Oct 18 - Sun, Nov 9
American Airlines Logo
1:27 pm - 7:15 amFSD-GRU
15h 48m1 stop
American Airlines Logo
12:15 am - 6:45 pmGRU-FSD
21h 30m2 stops
$1,184American Airlines
Find Deal
Mon, Oct 6 - Tue, Oct 21
LATAM Airlines Logo
5:30 am - 3:00 pmFSD-SCL
31h 30m2 stops
LATAM Airlines Logo
3:30 pm - 10:56 pmSCL-FSD
33h 26m3 stops
$3,122LATAM Airlines
Find Deal
Mon, Oct 6 - Mon, Oct 20
LATAM Airlines Logo
5:30 am - 6:45 amFSD-SCL
23h 15m2 stops
LATAM Airlines Logo
12:25 am - 10:56 pmSCL-FSD
24h 31m2 stops
$3,517LATAM Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on Delta ($788) and United Airlines ($838).

Good to know

Low seasonSeptember
Cheapest flight$788
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the afternoon, when round-trip flights cost $930 on average. Morning departures are around 33% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $1,450.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 10000 reviews
8.0Crew
7.5Boarding
6.5Food
7.2Comfort
6.9Entertainment
Airline reviews

Pretty good. The food was just mediocre, the boarding and crew were good.

8.0 ExcellentJoan, Aug 2025MIA - ORD
Read more American Airlines reviews

Pretty good. The food was just mediocre, the boarding and crew were good.

The comfort of the seats was great, the crew eased my child’s anxieties and the fact that I had full cans of my beverage choice was great.

My flight got switched and my prepaid bag didnt transfer over properly so I paid to check ANOTHER BAG. I was placed in a middle seat and it was just miserable. At least it was a bulkhead row so I had legroom. The flight just never seem3d to end

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

Sat on the ground in Cincinnati for 50 minutes before deplaning

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Was not able to watch most shows on the entertainment site. They would not load

As smooth as you can expect. Some issues with boarding because the previous plane took forever to deplane but overall, a good experience.

On Wednesday, July 30 we were in mid flight from Manchester to Charlotte and we turned around because the right engine was malfunctioning. That was the last flight out of Manchester that night. I was rebooked for Thursday, which became a weather event Friday. There were no seats left on the flight from Manchester to Charlotte. Consequently I didn’t leave Manchester until Saturday morning and we flew to Chicago so to say the least my scheduled flight and return to Iowa was three days off and it messed with my business schedule. Consequently cash flow. I would like some sort of acknowledgment of this event.

Everything you need to know for your flight to South America

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