$1,102 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Sat, Jul 11 - Mon, Aug 10
LATAM Airlines Logo
5:20 am - 1:35 pm
FSD
-
SCL
31h 15m
2 stops
LATAM Airlines Logo
11:05 pm - 10:09 pm
SCL
-
FSD
24h 04m
2 stops
$1,102LATAM Airlines
Sat, Jul 11 - Mon, Aug 10
LATAM Airlines Logo
5:20 am - 6:00 am
FSD
-
SCL
23h 40m
2 stops
LATAM Airlines Logo
11:00 pm - 10:09 pm
SCL
-
FSD
24h 09m
2 stops
$1,107LATAM Airlines
Sat, Jul 11 - Mon, Aug 10
Delta Logo
5:20 am - 7:15 am
FSD
-
SCL
24h 55m
1 stop
Delta Logo
11:25 pm - 10:09 pm
SCL
-
FSD
23h 44m
2 stops
$1,180Delta
Sat, Jul 11 - Mon, Aug 10
LATAM Airlines Logo
5:20 am - 1:35 pm
FSD
-
SCL
31h 15m
2 stops
LATAM Airlines Logo
8:30 am - 10:09 pm
SCL
-
FSD
38h 39m
3 stops
$1,182LATAM Airlines
Sat, Jul 11 - Mon, Aug 10
Delta Logo
5:20 am - 6:00 am
FSD
-
SCL
23h 40m
2 stops
Delta Logo
8:40 pm - 10:09 pm
SCL
-
FSD
26h 29m
1 stop
$1,191Delta
Sat, Jul 11 - Sun, Aug 9
LATAM Airlines Logo
5:20 am - 10:49 am
FSD
-
SCL
28h 29m
3 stops
LATAM Airlines Logo
12:40 am - 10:09 pm
SCL
-
FSD
22h 29m
2 stops
$1,207LATAM Airlines
Thu, Oct 15 - Mon, Oct 19
American Airlines Logo
7:30 am - 7:50 am
FSD
-
SCL
22h 20m
2 stops
American Airlines Logo
9:30 pm - 10:17 pm
SCL
-
FSD
26h 47m
2 stops
$1,250American Airlines
Thu, Oct 15 - Mon, Oct 19
LATAM Airlines Logo
5:25 am - 6:00 am
FSD
-
SCL
22h 35m
2 stops
LATAM Airlines Logo
12:05 am - 10:12 pm
SCL
-
FSD
24h 07m
2 stops
$1,276LATAM Airlines
Mon, May 4 - Thu, May 7
United Airlines Logo
6:42 pm - 9:40 am
FSD
-
GRU
12h 58m
1 stop
United Airlines Logo
10:20 pm - 9:52 pm
GRU
-
FSD
25h 32m
1 stop
$1,316United Airlines
Mon, May 4 - Thu, May 7
United Airlines Logo
3:15 pm - 9:40 am
FSD
-
GRU
16h 25m
1 stop
United Airlines Logo
10:20 pm - 10:45 am
GRU
-
FSD
14h 25m
1 stop
$1,478United Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on LATAM Airlines ($1,102) and Delta ($1,180).

Good to know

Cheapest flight$1,102
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11659 reviews
7.2Comfort
7.9Crew
6.4Food
7.5Boarding
6.9Entertainment
Airline reviews

On time departure and early arrival. Flight attendant very nice.

10.0 ExcellentKathryn, Apr 2026
LAX - OMA
Read more American Airlines reviews

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

For a 4 1/2 hour international flight all we got was 1 small pack of cookies and a drink. You had to watch movies on your own devise.

Airlines should be prohibited from using the seats they get away with.

My flight got delayed a total of five times. And the boarding gate changed four times. most of the time the platform was not up-to-date with the changes taking place. The most discouraging part of the entire trip by far.

Flight left early and arrived 30 MINUTES early at the destination. Smooth trip.

American delayed the flight for a crew rest period. The delay occurred late in the evening - the earliest i can find is 10:20 pm. With a 6 am flight anyone on the flight would have already have been asleep (unless you are insane, a vampire or on drugs) and at least for me i was already on the way to the airport at 445 am the next morning when i discovered they delayed the flight until 9 am. Given the incoming flight was in the air at 6 pm the evening before this should have been figured out a lot more timely that was there only crew to use. Just frustrating given there is no consideration for customer experience anymore in flying.

Returned home with a blood clot from flight homes and the uncomfortable aircraft I was on.

Everything you need to know for your flight to South America

Information on your arrival and departure airports