$320 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Tue, Mar 24 - Wed, Mar 25
LATAM Airlines Logo
5:10 am - 6:45 am
FSD
-
SCL
23h 35m
2 stops
LATAM Airlines Logo
12:20 am - 10:12 pm
SCL
-
FSD
23h 52m
2 stops
$873LATAM Airlines
Tue, Mar 24 - Thu, Mar 26
United Airlines Logo
11:21 am - 7:50 am
FSD
-
SCL
18h 29m
2 stops
United Airlines Logo
9:45 pm - 4:22 pm
SCL
-
FSD
20h 37m
2 stops
$878United Airlines
Mon, Feb 16 - Thu, Mar 26
United Airlines Logo
6:45 pm - 8:50 am
FSD
-
SCL
35h 05m
2 stops
United Airlines Logo
9:45 pm - 4:22 pm
SCL
-
FSD
20h 37m
2 stops
$956United Airlines
Mon, Feb 16 - Wed, Mar 25
LATAM Airlines Logo
5:08 am - 7:40 am
FSD
-
SCL
23h 32m
1 stop
LATAM Airlines Logo
12:20 am - 10:12 pm
SCL
-
FSD
23h 52m
2 stops
$1,059LATAM Airlines
Mon, Feb 16 - Thu, Mar 26
LATAM Airlines Logo
5:08 am - 5:35 am
FSD
-
SCL
21h 27m
2 stops
LATAM Airlines Logo
7:15 am - 10:12 pm
SCL
-
FSD
40h 57m
3 stops
$1,103LATAM Airlines
Sun, Mar 1 - Mon, Mar 9
Multiple Airlines Logo
2:16 pm - 5:40 am
FSD
-
GRU
36h 24m
2 stops
Multiple Airlines Logo
11:55 am - 11:11 am
GRU
-
FSD
25h 16m
1 stop
$1,116Multiple Airlines
Mon, Feb 16 - Thu, Mar 26
American Airlines Logo
5:44 am - 8:05 am
FSD
-
SCL
23h 21m
1 stop
American Airlines Logo
10:15 pm - 12:41 pm
SCL
-
FSD
16h 26m
1 stop
$1,142American Airlines
Sun, Mar 1 - Mon, Mar 9
LATAM Airlines Logo
5:08 am - 5:40 am
FSD
-
GRU
21h 32m
1 stop
LATAM Airlines Logo
11:45 pm - 10:12 pm
GRU
-
FSD
24h 27m
1 stop
$1,257LATAM Airlines
Mon, Feb 16 - Thu, Mar 26
LATAM Airlines Logo
5:08 am - 2:30 pm
FSD
-
SCL
30h 22m
3 stops
LATAM Airlines Logo
7:15 am - 10:12 pm
SCL
-
FSD
40h 57m
3 stops
$1,273LATAM Airlines
Sun, Mar 1 - Mon, Mar 9
United Airlines Logo
3:15 pm - 10:20 am
FSD
-
GRU
16h 05m
2 stops
United Airlines Logo
10:25 pm - 4:22 pm
GRU
-
FSD
19h 57m
2 stops
$1,307United Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on LATAM Airlines ($873) and United Airlines ($955).

Find deals

Good to know

Low seasonSeptember
Cheapest flight$873
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11197 reviews
7.2Comfort
6.9Entertainment
7.5Boarding
6.4Food
8.0Crew
Airline reviews

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

8.0 ExcellentMichelle, Jan 2026
DCA - SRQ
Read more American Airlines reviews

It was a little concerning to hear the ground crew arguing with the flight crew over baggage space. Instead of taking them and checking them, they started checking for space in the first class cabin moving items around like the flight crew didn't know what they were doing. I was embarrassed for them.

2 hour delay due to equipment failure. No updates via the app and airport screens (which continued to show a departure time in the past). AA eventually switched planes and the new plane was not catered or cleaned correctly.

I booked an aisle seat and was given a middle. At 6'4" 230lbs, it is not ideal to fly in the middle row for myself and passengers.

Trip delayed for 2 hours because of rain. We boarded and have to get down the flight and reboard again.

The aircraft had several problems - from excess fuel to non operational ac. Two hours of delay in Chicago could have been avoided with proper planning and aircraft maintenance.

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

Could we please end the loud announcements about credit card offers on your flights? We are trying to sleep, work, watch videos, etc. and if we need a credit card, we will ask for one. Flying is already not what it used to be.

I would like the crew to talk LESS over the PA and specifically about credit card offers. I am trying to work, sleep, watch a movie and the PA was booming about a credit card offer. Could we go back to the days when the customer was more important than selling a credit card?

Enough space,crew was helpful,food was good.The gates are way far especially for travelers with health issues

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Sioux Falls (FSD)