$863 Find Cheap Flights from Sioux Falls to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

수, 4월 1 - 수, 4월 8
LATAM Airlines Logo
5:20 am - 6:35 am
FSD
-
SCL
23h 15m
2 stops
LATAM Airlines Logo
11:05 pm - 10:12 pm
SCL
-
FSD
24h 07m
2 stops
$863LATAM Airlines
화, 3월 24 - 목, 3월 26
United Airlines Logo
5:45 am - 7:50 am
FSD
-
SCL
24h 05m
2 stops
United Airlines Logo
9:45 pm - 11:44 pm
SCL
-
FSD
27h 59m
2 stops
$878United Airlines
수, 4월 1 - 수, 4월 8
LATAM Airlines Logo
5:20 am - 8:15 am
FSD
-
SCL
24h 55m
1 stop
LATAM Airlines Logo
11:05 pm - 10:12 pm
SCL
-
FSD
24h 07m
2 stops
$893LATAM Airlines
수, 4월 1 - 수, 4월 8
LATAM Airlines Logo
5:20 am - 8:15 am
FSD
-
SCL
24h 55m
1 stop
LATAM Airlines Logo
8:40 pm - 10:12 pm
SCL
-
FSD
26h 32m
1 stop
$898LATAM Airlines
일, 3월 22 - 일, 3월 29
LATAM Airlines Logo
5:20 am - 5:50 am
FSD
-
SCL
22h 30m
2 stops
LATAM Airlines Logo
8:00 pm - 10:12 pm
SCL
-
FSD
52h 12m
2 stops
$937LATAM Airlines
금, 3월 20 - 금, 3월 27
American Airlines Logo
1:26 pm - 7:00 am
FSD
-
SCL
15h 34m
1 stop
American Airlines Logo
10:15 pm - 12:41 pm
SCL
-
FSD
16h 26m
1 stop
$938American Airlines
금, 3월 20 - 금, 3월 27
United Airlines Logo
7:43 am - 7:50 am
FSD
-
SCL
22h 07m
2 stops
United Airlines Logo
9:45 pm - 8:40 pm
SCL
-
FSD
24h 55m
2 stops
$943United Airlines
금, 3월 20 - 금, 3월 27
American Airlines Logo
5:44 am - 7:00 am
FSD
-
SCL
23h 16m
1 stop
American Airlines Logo
10:15 pm - 12:41 pm
SCL
-
FSD
16h 26m
1 stop
$1,013American Airlines
금, 3월 20 - 금, 3월 27
American Airlines Logo
6:50 am - 7:00 am
FSD
-
SCL
22h 10m
2 stops
American Airlines Logo
9:20 pm - 4:51 pm
SCL
-
FSD
21h 31m
2 stops
$1,018American Airlines
목, 8월 13 - 금, 8월 21
American Airlines Logo
5:15 pm - 9:00 am
FSD
-
GRU
13h 45m
1 stop
American Airlines Logo
10:00 pm - 4:35 pm
GRU
-
FSD
20h 35m
1 stop
$1,103American Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South America were found on LATAM Airlines ($863) and United Airlines ($878).

Good to know

Cheapest flight$863
Flight from Sioux Falls to Santiago

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11339 reviews
6.4Food
8.0Crew
7.5Boarding
6.9Entertainment
7.2Comfort
Airline reviews

Never ontime and always delays. Long waits for customer service and often app doesn’t work

6.0 GoodGovinda, Feb 2026
DFW - MSN
Read more American Airlines reviews

Never ontime and always delays. Long waits for customer service and often app doesn’t work

Arriving plane went to wrong gate. Flight Attendant was late. Was in no Hurry when he arrived. Flight was fine. Plane had to wait 20 minutes to get assigned a gate due to designated gate tied up. barely connected.. Boarded extremely late on final leg of trip.

We arrived 25 minutes early only to be told our gate was occupied and so we sat for close to 30 minutes to pull into a gate. That’s not an early arrival!

Experience was great. The best part is the free Wi-Fi connection which helps me to work on the flight

The gate agent had a really bad attitude and refused to help me get on the standby list. She just handed me a card and said I needed to call a number. I asked her to help with the AA app on my phone and she just shrugged and said she didnt know. After a few phone calls, I eventually just went to a different gate agent on the other side of the terminal and got the help I needed.

The TSA check in took 1.5 hours to get through in Austin and I missed my flights back to DC

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Overall, my last three trips on American Airlines have all been either delayed or "rescheduled" due to mechanical issues. At least on delay caused me to miss two possible connecting flights each later than the first. My last option for my last connection required the assistance of the onsite service desk (O'Hare Airport). The wait time for the service desk was such that it jeopardized getting booked on the last connecting flight available for the night. Suffice it to say, my latest experiences with American Airlines have caused me extensive loss of productive business and personal time and can therefore be classified as significantly less than satisfactory.

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Waiting for gate in RDU for more than 20mins is crazy.

Everything you need to know for your flight to South America

Information on your arrival and departure airports