$690 Find Cheap Flights from Sioux Falls to South America - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South America departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Sioux Falls to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South America

Fri, Dec 18 - Sat, Jan 9
LATAM Airlines Logo
5:25 am - 6:55 amFSD  Sioux Falls Joe Foss Field-SCL Santiago Arturo Merino Benitez
22h 30m2 stops Atlanta Hartsfield-Jackson Miami
LATAM Airlines Logo
8:35 am - 10:12 pmSCL  Santiago Arturo Merino Benitez-FSD Sioux Falls Joe Foss Field
40h 37m2 stops Miami Atlanta Hartsfield-Jackson
$2,033LATAM Airlines
Fri, Dec 18 - Sat, Jan 9
LATAM Airlines Logo
5:25 am - 7:40 amFSD  Sioux Falls Joe Foss Field-SCL Santiago Arturo Merino Benitez
23h 15m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
11:55 pm - 10:12 pmSCL  Santiago Arturo Merino Benitez-FSD Sioux Falls Joe Foss Field
25h 17m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$2,394LATAM Airlines
Fri, Dec 18 - Sat, Jan 9
American Airlines Logo
6:45 am - 7:45 amFSD  Sioux Falls Joe Foss Field-SCL Santiago Arturo Merino Benitez
22h 00m1 stop Dallas/Fort Worth
American Airlines Logo
11:45 pm - 10:16 pmSCL  Santiago Arturo Merino Benitez-FSD Sioux Falls Joe Foss Field
25h 31m1 stop Dallas/Fort Worth
$4,510American Airlines
Fri, Dec 18 - Sat, Jan 9
LATAM Airlines Logo
5:25 am - 11:41 amFSD  Sioux Falls Joe Foss Field-SCL Santiago Arturo Merino Benitez
27h 16m3 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl Buenos Aires Jorge Newbery
LATAM Airlines Logo
11:55 pm - 10:12 pmSCL  Santiago Arturo Merino Benitez-FSD Sioux Falls Joe Foss Field
25h 17m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$6,887LATAM Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South America flights

Get data-powered insights and trends into flights from Sioux Falls to South America to help you find the cheapest flights, the best time to fly and much more.

How long does a flight from Sioux Falls to South America take?

The duration of a flight to South America depends on your arrival airport. The shortest routes to South America from Sioux Falls are to Santiago, which takes 22h 30m, and Sao Paulo, which takes 23h 53m.

Good to know

Cheapest flight

$690
Flight from Sioux Falls to Sao Paulo

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Sioux Falls to South America

 
Need help choosing which airline to fly with from Sioux Falls to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11867 reviews
6.4Food
7.9Crew
6.8Entertainment
7.2Comfort
7.5Boarding
Airline reviews

The flight was over an hour delayed. The problem was they had the wrong aircraft at the gate, Joe in the world does that happen?

2.0 MediocreThomas, Aug 2026
Read more American Airlines reviews

The flight was over an hour delayed. The problem was they had the wrong aircraft at the gate, Joe in the world does that happen?

My flight was delayed several hours, which is to be expected (American never fails to disappoint me!), but the parts that really bothered me are as follows: 1) I was unable to add myself to the standby list for another flight in the app, nor could the gate agents figure out how to help me do so (the app is difficult to work with and simply did not allow me to perform the action of adding myself to the list) 2) When I asked the gate agents to add me to the standby list, the agent said that he had added me, but I was not able to confirm that I was on the list in the app; as it turns out, I had NOT been added to the list after all. He had lied to me and/or failed to add me to the list. 3) I figured out I had not been added to the standby list when I spoke to the (rather rude, snippy, and dismissive) other gate agent, who finally did add me to the list after giving me some pretty unnecessary attitude. I understand that gate agents experience the worst of stressed travelers every day, so I appreciate that I was eventually able to make it onto the standby flight with their help. However, the app needs some SERIOUS attention!

The power outlets were not working for my row. Also felt like the seats have gotten smaller. I was in the window seat and felt like suffocated, as the two passengers next to me were tall and wide.

Delays and multiple changes in gates. In accurate info sent to phone. Worst flight in years. With no apologies or recompense.

No AC, no beverage service and no explanation from the captain. 4 flight legs in 2 days with no internet service.

No service on New Orleans to DFW or DFW to San Antonio. Also no explanation from the captain why we had no AC. Unacceptable!

They lost my bag on both the going and return flight of my round-trip.

Flight was on time and the flight crew was exceptional.

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Everything you need to know for your flight to South America

Information on your arrival and departure airports