$321 Find Cheap Flights from Sioux Falls to South Carolina - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Sioux Falls to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Charleston
Charleston1 stop$321
Myrtle Beach
Myrtle Beach2 stops$354
Greenville
Greenville1 stop$321
Charlotte
Charlotte1 stop$349
Charleston
Charleston1 stop$321
Myrtle Beach
Myrtle Beach2 stops$354
Greenville
Greenville1 stop$321
Charlotte
Charlotte1 stop$349
Booking Insights

KAYAK's insights & trends for Sioux Falls to South Carolina flights

Get data-powered insights and trends into flights from Sioux Falls to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Sioux Falls to South Carolina?

Flight prices are below average for this route right now.

Flights to South Carolina from Sioux Falls usually cost between $351 and $676 in October.
The lowest price found in the past 5 days was $321 on American Airlines (Oct 24-Oct 31).

What is the cheapest month to fly from Sioux Falls to South Carolina?

The cheapest month for flights from Sioux Falls to South Carolina is August, when tickets cost $349 (return) on average. On the other hand, the most expensive months are October and May, when the average cost of round-trip tickets is $676 and $600 respectively.

Good to know

Low season

February

Cheapest flight

$321
Best time to beat the crowds with an average 28% drop in price.
Most popular time to fly with an average 7% increase in price.
Flight from Sioux Falls to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Sioux Falls to South Carolina

 
Need help choosing which airline to fly with from Sioux Falls to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8605 reviews
7.2Food
7.8Comfort
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

The WiFi on the plane was out. I also thought movie options were lacking.

8.0 ExcellentMichael, Sep 2026
Read more Delta reviews

The WiFi on the plane was out. I also thought movie options were lacking.

They changed my seat assignment from window to middle. I have a physical need to sit by the window because of spinal issues. I unboarded in pain, I also was placed between 2 very large men. I am very disappointed and now dealing with the physical aftermath.

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

The united employees at the gate treated me very rudely and called me nefarious

The food was horrible. There was no. Wifi, and it was just terrible from bangkok to d. C

My flight got cancelled. Couldn’t get my luggage. It arrived at my destination ahead of me. I didn’t get my preordered meal. Had to spend the night in the airport.

The crew was good, the WiFi was amazing, but the plane was meh. Uncomfortable first class, not enough room for baggage. My stuff ended up being behind my seat, so I had to sit on the plane for 20 minutes before I could get to it after landing.

food /beverage service was limited to one time which was unexpected for a flight that long. food wasn't very good.

United did nit provide any updated on flight crew not bein available until boarding time started. It was bad. Itws alate night flight and there no proactive communication and iha d an important meeting that i missed due to thus

From the boarding crew to the FAs was such a good team. All with smiles and positive energy. The pilots made an announcement of us waiting on some passengers who were late landing and I didn’t hear one person feel like it was an inconvenience which was wonderful. Massive kudos to all that worked that flight. Everyone was united. 😊💙

Awful. No counter attendants. No dinner offered due to delays.

Why wasn't this flight departure scheduled eith another crew so that it could leave on time? When we arrived in Denver we had so little time between flights we had run to the connecting flight. We should received some credit for the inconvenience.

My flight was 3 hours late, which caused me to miss my connection in Denver. Further, this connecting flight was then Later canceled. This required me to stay another night an hour and a half away, and rent the rental car for an additional Night. I am still waiting for United Airlines to reimburse me for the inconvenience and Expense of having to extend my rental Car for An additional Day. See attached receipt. https://share.icloud.com/photos/0f5ns2AaeIr7w6t_uH1qfPBUg

Comfy and timely flight thanks to Cathay to all crew and the captain for our smooth landing.. above all thank You Lord for our Safe flight ❤️🙌🙏🏽

Flight took additional prep time since plane came from Mexico, which resultrd in boarding and plane prep being delayed for additional cleaning procedures. Once boarded, plane tire was identified as being low on air and needed to be replaced, which creared the need to deboard and further delays for what was already a late night flight. Would have expected a better scheduled turn around and prep buffer that would have not created that degree of delay and deboarding

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

More options for your flight from Sioux Falls to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental