$131 Find Cheap Flights from Sioux Falls to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South Carolina departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Sioux Falls to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$291
Myrtle Beach
Myrtle Beach2 stops$324
Greenville
Greenville1 stop$355
Hilton Head Island
Hilton Head Island1 stop$1,515
Charlotte
Charlotte1 stop$319
Charleston
Charleston1 stop$291
Myrtle Beach
Myrtle Beach2 stops$324
Greenville
Greenville1 stop$355
Hilton Head Island
Hilton Head Island1 stop$1,515
Charlotte
Charlotte1 stop$319

Book Cheap Sioux Falls to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South Carolina

Wed, Oct 28 - Tue, Nov 3
American Airlines Logo
7:03 am - 3:02 pm
FSD
-
CHS
6h 59m
1 stop
American Airlines Logo
7:16 am - 2:18 pm
CHS
-
FSD
8h 02m
1 stop
$291American Airlines
Wed, Oct 28 - Tue, Nov 3
American Airlines Logo
2:48 pm - 11:59 pm
FSD
-
CHS
8h 11m
1 stop
American Airlines Logo
5:10 am - 12:36 pm
CHS
-
FSD
8h 26m
2 stops
$296American Airlines
Wed, Sep 2 - Sun, Sep 6
United Airlines Logo
7:47 am - 1:58 pm
FSD
-
CHS
5h 11m
1 stop
United Airlines Logo
4:28 pm - 11:22 pm
CHS
-
FSD
7h 54m
1 stop
$300United Airlines
Tue, Sep 1 - Sun, Sep 6
American Airlines Logo
12:06 pm - 7:20 pm
FSD
-
CHS
6h 14m
1 stop
American Airlines Logo
7:50 pm - 12:25 am
CHS
-
FSD
5h 35m
1 stop
$305American Airlines
Wed, Sep 2 - Sun, Sep 6
American Airlines Logo
12:57 pm - 11:00 pm
FSD
-
CHS
9h 03m
2 stops
American Airlines Logo
7:50 pm - 12:25 am
CHS
-
FSD
5h 35m
1 stop
$310American Airlines
Mon, Aug 31 - Sun, Sep 6
United Airlines Logo
7:47 am - 1:58 pm
FSD
-
CHS
5h 11m
1 stop
United Airlines Logo
4:28 pm - 11:22 pm
CHS
-
FSD
7h 54m
1 stop
$314United Airlines
Tue, Oct 6 - Tue, Oct 20
Delta Logo
5:30 am - 11:38 am
FSD
-
SAV
5h 08m
1 stop
Delta Logo
2:38 pm - 7:56 pm
SAV
-
FSD
6h 18m
1 stop
$319Delta
Wed, Sep 9 - Sun, Sep 13
Delta Logo
10:40 am - 4:13 pm
FSD
-
CLT
4h 33m
1 stop
Delta Logo
6:20 am - 12:19 pm
CLT
-
FSD
6h 59m
1 stop
$319Delta
Fri, Aug 14 - Thu, Aug 20
Delta Logo
5:00 am - 2:53 pm
FSD
-
CAE
8h 53m
2 stops
Delta Logo
1:59 pm - 7:59 pm
CAE
-
FSD
7h 00m
1 stop
$324Delta
Wed, Sep 9 - Sat, Sep 12
United Airlines Logo
7:47 am - 2:05 pm
FSD
-
CLT
5h 18m
1 stop
United Airlines Logo
3:00 pm - 11:12 pm
CLT
-
FSD
9h 12m
2 stops
$324United Airlines
Booking Insights

KAYAK's insights & trends for Sioux Falls to South Carolina flights

Get data-powered insights and trends into flights from Sioux Falls to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Sioux Falls to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Sioux Falls to South Carolina departing in October.

What is the cheapest month to fly from Sioux Falls to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Sioux Falls to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Sioux Falls to South Carolina is September, when tickets cost $160 (return) on average. On the other hand, the most expensive months are February and January, when the average cost of round-trip tickets is $335 and $314 respectively.

Good to know

Low seasonFebruary
Cheapest flight$131
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 10% increase in price.
Flight from Sioux Falls to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Sioux Falls to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Sioux Falls to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Sioux Falls to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8453 reviews
8.1Boarding
7.8Entertainment
7.8Comfort
7.2Food
8.5Crew
Airline reviews

Our flight was delayed by over 4 hours due to a maintenance issue. They announced a new plane was on the way. We were given a $12 food voucher ( airport food is quite expensive You can’t even by a water and a small snack for 12:00. 4 hours later we boarded and landed in Atlanta at 10:20 ish pm. Of course we missed our connection and we were given a hotel voucher and another food voucher ! We didn’t make it home until 11:00 the next day ! Unacceptable

2.0 MediocreAnonymous, Jul 2026
MCI - ATL
Read more Delta reviews

Our flight was delayed by over 4 hours due to a maintenance issue. They announced a new plane was on the way. We were given a $12 food voucher ( airport food is quite expensive You can’t even by a water and a small snack for 12:00. 4 hours later we boarded and landed in Atlanta at 10:20 ish pm. Of course we missed our connection and we were given a hotel voucher and another food voucher ! We didn’t make it home until 11:00 the next day ! Unacceptable

Everything about this flight was good except for the very end when I reached my destination. Everyone from the tune to the wheelchair escorts were great with the case were great but I miss you with people at the check in this at the very end. I need help from the chicken desk because I forgot my pillow on the plane The female worker at the chicken desk said that they found my pillow and she was going to retrieve it for me. She left a 30 minutes without any update and her so she saw me walking back and forth waiting for her and they didn't even bother calling her or radioing her for any updates. They were busy because they were behind schedule and they were overwhelmed but thanks because at least glanced me and try to give me an update just a quick radio check or phone call. I don't care about the pillow but if you tell me to wait, I waited for at least half an hour before I said something and I just left because they wouldn't bother talking to me so I could, so everything's going in the review. I took pictures of the two men that were left working at the check-in counter. The totally ignored me despite the signals I've been giving them. I don't see any offers in the kayak review to add pictures or screenshots so I'm going to post another review I don't know their name but I'm pretty sure Delta will find other names when they see the review. Google with pictures. There was another guy at the chicken counter bring an orange workers vest who finally left after telling me that the girl that was retrieving my pillow is working the gates now. That would have been if they just told me that's what happened. But I had no update. Make me wait for nothing. Thank you Delta airlines!

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

The flight was delayed by a hour and I wish they had communicated it sooner. No issues on the plane, it did take a while for food to come.

Know that the movies that you are going to be offered are the oldest be rated movies they could possibly get. They may have one or two new movies that they keep advertising but when you’re flying 15 hours, there is nothing to see past the first new movie.

Great staff. Clean plane, but we were delayed for more than an hour due to maintenance issues and had to board another plane.

I was exhausted from a long day. The flight was smooth. The first flight during my 3 week travel that took off on time.

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

Awful. Delayed flights, missed connection to Toronto. Hotel vouchers were for already booked hotels x3. Giant waste of my time

Horrible I am at almost 2,000,000 miles on United. This was probably the worst flight ever. An hour and a half before takeoff I get a message that they’re changing the plane and I no longer have a seat in Polaris business Supposedly, there was a problem with the plane, but then there was no other plane Finally, they decided to bring a plane from Newark to Washington Dulles Of course the original flight was at 10:45 PM so by the time the plane got there it was 12:30 AM. It had not been cleaned. It had not been catered. They don’t really have people available to do those things when it’s not pre-programmed at 1 o’clock in the morning. The crew had to be changed And the new plane held 28 fewer people than the scheduled plane There is no way you can hate United Airlines enough The people at the gate were actually just fine, but it was management who was completely useless And did they send extra help to the people at the gate? Did they send supervisors? Of course not. Just don’t take United find somebody else or buy a boat

Awful. No counter attendants. No dinner offered due to delays.

Why wasn't this flight departure scheduled eith another crew so that it could leave on time? When we arrived in Denver we had so little time between flights we had run to the connecting flight. We should received some credit for the inconvenience.

My flight was 3 hours late, which caused me to miss my connection in Denver. Further, this connecting flight was then Later canceled. This required me to stay another night an hour and a half away, and rent the rental car for an additional Night. I am still waiting for United Airlines to reimburse me for the inconvenience and Expense of having to extend my rental Car for An additional Day. See attached receipt. https://share.icloud.com/photos/0f5ns2AaeIr7w6t_uH1qfPBUg

I found the seats ergonomically uncomfortable forcing the body to seat slightly hunched. For a short flight I worked on adjustments but for a longer flight, it would be difficult.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

Pros: "Nothing"
Cons: "Getting all my luggage. Allowing my wife and I to sit together"

Everything you need to know for your flight from Sioux Falls to South Carolina

Information on your arrival and departure airports