$218 Find Cheap Flights from Sioux Falls to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South Carolina departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Sioux Falls to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Sioux Falls to South Carolina, as well as popular online travel agencies
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Cheap Flights from Sioux Falls to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$279
Myrtle Beach
Myrtle Beach1 stop$291
Greenville
Greenville1 stop$251
Charlotte
Charlotte1 stop$265
Charleston
Charleston1 stop$279
Myrtle Beach
Myrtle Beach1 stop$291
Greenville
Greenville1 stop$251
Charlotte
Charlotte1 stop$265

Book Cheap Sioux Falls to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South Carolina

Sun, Mar 8 - Tue, Mar 17
Delta Logo
5:00 am - 11:55 am
FSD
-
CLT
5h 55m
1 stop
Delta Logo
6:47 pm - 11:04 pm
CLT
-
FSD
5h 17m
1 stop
$265Delta
Mon, Mar 9 - Thu, Mar 12
Multiple Airlines Logo
6:11 pm - 2:17 pm
FSD
-
CLT
19h 06m
1 stop
Multiple Airlines Logo
7:43 pm - 7:59 pm
CLT
-
FSD
25h 16m
1 stop
$277Multiple Airlines
Sat, Apr 4 - Sat, Apr 11
American Airlines Logo
2:07 pm - 10:48 pm
FSD
-
SAV
7h 41m
1 stop
American Airlines Logo
5:40 am - 11:59 am
SAV
-
FSD
7h 19m
1 stop
$279American Airlines
Sun, Jun 28 - Sat, Jul 4
United Airlines Logo
7:40 am - 1:50 pm
FSD
-
CLT
5h 10m
1 stop
United Airlines Logo
4:22 pm - 11:49 pm
CLT
-
FSD
8h 27m
1 stop
$279United Airlines
Tue, Jul 21 - Tue, Jul 28
Delta Logo
8:15 am - 2:05 pm
FSD
-
CHS
4h 50m
1 stop
Delta Logo
4:30 pm - 10:11 pm
CHS
-
FSD
6h 41m
1 stop
$279Delta
Sat, May 23 - Sat, May 30
American Airlines Logo
7:02 am - 4:29 pm
FSD
-
CLT
8h 27m
1 stop
American Airlines Logo
7:46 am - 4:14 pm
CLT
-
FSD
9h 28m
1 stop
$281American Airlines
Sun, Jun 28 - Sat, Jul 4
United Airlines Logo
7:40 am - 1:50 pm
FSD
-
CLT
5h 10m
1 stop
United Airlines Logo
10:26 am - 6:00 pm
CLT
-
FSD
8h 34m
2 stops
$284United Airlines
Sat, Apr 4 - Sat, Apr 11
American Airlines Logo
12:14 pm - 9:44 pm
FSD
-
SAV
8h 30m
2 stops
American Airlines Logo
5:40 am - 11:59 am
SAV
-
FSD
7h 19m
1 stop
$284American Airlines
Sat, Apr 11 - Thu, Apr 16
United Airlines Logo
3:10 pm - 11:59 pm
FSD
-
CHS
7h 49m
2 stops
United Airlines Logo
4:55 pm - 9:49 pm
CHS
-
FSD
5h 54m
1 stop
$284United Airlines
Tue, Mar 10 - Wed, Mar 11
Delta Logo
11:01 am - 5:48 pm
FSD
-
CLT
5h 47m
1 stop
Delta Logo
6:18 am - 10:21 am
CLT
-
FSD
5h 03m
1 stop
$285Delta
Booking Insights

KAYAK's insights & trends for Sioux Falls to South Carolina flights

Get data-powered insights and trends into flights from Sioux Falls to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South Carolina were found on Delta ($277) and American Airlines ($279).

Good to know

Low seasonFebruary
Cheapest flight$218
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from Sioux Falls to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Sioux Falls to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Sioux Falls to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Sioux Falls to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8208 reviews
8.5Crew
7.2Food
7.8Entertainment
8.1Boarding
7.9Comfort
Airline reviews

First flight out and was 85 minutes delayed. Notification came out way too late

4.0 OkayJason, Feb 2026
SEA - SLC
Read more Delta reviews

First flight out and was 85 minutes delayed. Notification came out way too late

Delta flights recently are always delayed AND at jfk tney get the gates further away (need To walk 20’ to get to them/all the way at the end of the terminal). Not sure whats happening but price doesnt match experience!

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Good experience and the flight landed early. There was no food I had or entertainment.

Flight was delayed and no reasons provided. After the passengers were boarded, the crew made announcement that the captain has jot arrived and he would take another 15 mins. All passengers patiently sat until the captain came and started. Terrible experience!

Flight was delayed. No information on why it was delayed. After we boarded the flight, , the crew made announcement that the captain hs not arrived and he will take 15 mins more to arrive. Passengers were just sitting patiently for the captain to arrive and start, Terrible experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

Smallest leg room I've ever had on a plane.

As great a red-eye flight as red-eye flights can be.

Very old flight - time to retire it for newer airplanes

2+ hours delayed Outlet in row 12 did not work Tv monitors did not work Lights kept off the entire flight for at 5pm-7pm flight

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

No Snacks or Entertainment. The flight was short, snacks should still be given.

We lost a day of our vacation because AA did not get the plane to the gate on time. Even though the gate attendant was very clear that it was not weather related, AA would do nothing because there was some snow that day. They basically said the gate attendant was wrong even though she was on the front line of the situation and they were not.

See prior comment about how Kayak mishandled my reservation and delayed my arrival by 6 hours.

American Airlines was great and worked very hard to change my ticket so I could get an earlier, direct flight back to Dallas. However, I was informed that Kayak made mistakes with my itinerary and classified my ticket as desiring to be on the earlier flight instead of taking the necessary step of calling AA to get me on the standby list. This ended up keeping me from being added to the standby list and delayed me getting home by 6 hours. I am happy to discuss this further with Kayak so they can correct their procedures so this won't happen again.

The flight was fine. It's the satellite terminal that supports American eagle flights is what sucks. There is only one food option and everything there is way overpriced. I mean I know it's airport pricing, but it's even crazier than that. I bought a sandwich in a plastic container for $18.

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

The smell from the bathroom kept wafting through the cabin. It made people sick.

The flight was really crowded. Flight attendants were just ok.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Didn't get a seat assignment until the last minute even though i picked a seat.

Everything you need to know for your flight from Sioux Falls to South Carolina

Information on your arrival and departure airports