$127 Find Cheap Flights from Sioux Falls to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South Carolina departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Sioux Falls to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Sioux Falls to South Carolina, as well as popular online travel agencies
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Cheap Flights from Sioux Falls to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$323
Myrtle Beach
Myrtle Beach1 stop$279
Greenville
Greenville1 stop$291
Charlotte
Charlotte1 stop$161
Charleston
Charleston1 stop$323
Myrtle Beach
Myrtle Beach1 stop$279
Greenville
Greenville1 stop$291
Charlotte
Charlotte1 stop$161

Book Cheap Sioux Falls to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South Carolina

Fri, Apr 17 - Thu, Apr 23
Frontier Logo
8:06 pm - 4:56 pm
FSD
-
CLT
19h 50m
1 stop
Frontier Logo
6:18 pm - 7:21 pm
CLT
-
FSD
26h 03m
1 stop
$161Frontier
Mon, Apr 6 - Fri, Apr 10
Multiple Airlines Logo
5:46 pm - 8:21 am
FSD
-
CLT
13h 35m
1 stop
Multiple Airlines Logo
9:05 am - 5:21 pm
CLT
-
FSD
9h 16m
1 stop
$234Multiple Airlines
Fri, Apr 17 - Sun, Apr 19
Frontier Logo
8:06 pm - 4:56 pm
FSD
-
CLT
19h 50m
1 stop
Frontier Logo
6:18 pm - 7:21 pm
CLT
-
FSD
26h 03m
1 stop
$236Frontier
Fri, May 1 - Mon, May 4
Multiple Airlines Logo
6:11 pm - 9:10 am
FSD
-
CLT
13h 59m
1 stop
Multiple Airlines Logo
8:56 am - 5:21 pm
CLT
-
FSD
9h 25m
1 stop
$252Multiple Airlines
Sat, Apr 25 - Sat, May 2
United Airlines Logo
6:10 am - 2:17 pm
FSD
-
MYR
7h 07m
1 stop
United Airlines Logo
3:14 pm - 9:52 pm
MYR
-
FSD
7h 38m
1 stop
$291United Airlines
Sat, Apr 25 - Sat, May 2
United Airlines Logo
7:39 am - 5:09 pm
FSD
-
MYR
8h 30m
2 stops
United Airlines Logo
3:14 pm - 9:52 pm
MYR
-
FSD
7h 38m
1 stop
$296United Airlines
Sat, Aug 8 - Wed, Aug 12
American Airlines Logo
7:30 am - 2:53 pm
FSD
-
CHS
6h 23m
1 stop
American Airlines Logo
7:54 pm - 12:27 am
CHS
-
FSD
5h 33m
1 stop
$323American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
12:29 pm - 10:36 pm
FSD
-
CHS
9h 07m
2 stops
American Airlines Logo
7:07 am - 11:59 am
CHS
-
FSD
5h 52m
1 stop
$328American Airlines
Sat, Aug 15 - Tue, Aug 18
Delta Logo
10:58 am - 4:30 pm
FSD
-
SAV
4h 32m
1 stop
Delta Logo
5:35 pm - 10:09 pm
SAV
-
FSD
5h 34m
1 stop
$339Delta
Thu, Aug 20 - Tue, Aug 25
Delta Logo
5:15 am - 4:35 pm
FSD
-
SAV
10h 20m
2 stops
Delta Logo
5:10 pm - 10:46 pm
SAV
-
FSD
6h 36m
1 stop
$374Delta
Booking Insights

KAYAK's insights & trends for Sioux Falls to South Carolina flights

Get data-powered insights and trends into flights from Sioux Falls to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Sioux Falls to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Sioux Falls to South Carolina were found on United Airlines ($291) and American Airlines ($323).

Good to know

Low seasonFebruary
Cheapest flight$127
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Sioux Falls to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Sioux Falls to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Sioux Falls to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Sioux Falls to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8319 reviews
7.8Entertainment
8.1Boarding
7.9Comfort
7.2Food
8.5Crew
Airline reviews

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

2.0 MediocreSreekumar, Mar 2026
FLL - DTW
Read more Delta reviews

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Entertainment is ok! Boarding and seat with zone is terrible. I paid for the seats but you didn’t give me what I paid for which is exit isles.

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

I will never fly ANA again. They lost one of my large pieces of checked luggage, the heaviest one with the most valuable items in it, and they said they will not send me an email unless they can't find it, even though the paper they gave me to track the status of my lost luggage requires a code from an email they are supposed to send me so I can do baggage tracing. They claim to be an international airline, but they also insist on calling a Japanese telephone number to confirm where to send the lost baggage if they find it. It is impossible to find an actual contact email address for customer support on their website, and their AI chatbot is unhelpful, directing you to a webpage that says it is for contact information but does not have any actual email addresses or phone numbers listed on it. My seat in economy did not recline at all, even though I was not sitting in an exit row nor the very back row. I had to sit in the fully upright position for over ten hours of international travel. Awful experience overall.

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Good quick flight on a small but comfortable plane. I'm 6'3 and had plenty of space.

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

A first class seat should fit a fat person, and this doesn't. The trays in the armrest are less functional than an ordinary tray in the back of the seat.

The flight attendant was friendly and efficient. The temperature was kept nice and cool. The plane was nice, but filthy. There were visible spills on my tray table. The gate agent was somewhat rude with her announcements and in speaking with other customers.

I appreciate that I finally got the seat I paid extra for this time. Thank you

I would have liked vegetarian and gluten free options for evening dinner time flight. I would have like a pillow on the international overnight flight . The veg wrap and oaten desert on the international flight was good

The experience at checkin for my American Airlines flight from Sacramento to LAX was very good including the assistance I received in getting my bags checked in and boarding passes printed. Was pleasantly surprised the my bags were checked through all the way to my destination at Clark International Airport in Angeles, Philippines.

Absolutely terrible. Would never fly American again. 2 deplaned incidents and delayed by close to 24 hours. $12 meal voucher for first class passengers was an insult to the injury. Pathetic.

Terrible planning. And even worse gate agents. Absolutely rude behavior.

Half of the TSA checkpoints at PHL are closed. Also, there is no standby for first class passengers. You can only standby for coach. Very dated policy and inconsistent with peers.

Flight was scheduled at 11:26am but they keep Delaying until midnight. They waited at airport restless.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Everything you need to know for your flight from Sioux Falls to South Carolina

Information on your arrival and departure airports