$298 Find Cheap Flights from Sioux Falls to South Carolina - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Sioux Falls to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Charleston
Charleston1 stop$321
Myrtle Beach
Myrtle Beach1 stop$399
Greenville
Greenville1 stop$325
Charlotte
Charlotte1 stop$329
Charleston
Charleston1 stop$321
Myrtle Beach
Myrtle Beach1 stop$399
Greenville
Greenville1 stop$325
Charlotte
Charlotte1 stop$329
Booking Insights

KAYAK's insights & trends for Sioux Falls to South Carolina flights

Get data-powered insights and trends into flights from Sioux Falls to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Sioux Falls to South Carolina?

Flight prices are below average for this route right now.

Flights to South Carolina from Sioux Falls usually cost between $378 and $503 in January.
The lowest price found in the past 5 days was $321 on Delta (Jan 20-Jan 26).

What is the cheapest month to fly from Sioux Falls to South Carolina?

The cheapest month for flights from Sioux Falls to South Carolina is August, when tickets cost $324 (return) on average. On the other hand, the most expensive months are October and April, when the average cost of round-trip tickets is $619 and $520 respectively.

Good to know

Low season

February

Cheapest flight

$298
Best time to beat the crowds with an average 28% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Sioux Falls to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Sioux Falls to South Carolina

 
Need help choosing which airline to fly with from Sioux Falls to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8568 reviews
7.8Entertainment
8.5Crew
7.8Comfort
8.1Boarding
7.2Food
Airline reviews

Flight was delayed at airport with large backlog and WiFi was spotty

6.0 GoodAnn, Sep 2026
Read more Delta reviews

Flight was delayed at airport with large backlog and WiFi was spotty

I don’t like mushrooms and that’s all they had with pasta

Flight was delayed before take off and at landing. Baggage took 20 minutes. Flight crew would not serve full soft drink and had to ask multiple times before receiving water.

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

I am still at the Airport! Delayed Delayed and Delyaed

The landing was the worst I’ve experienced with a flight.

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

All good on Delta's part. Passengers could be a little more courteous to each other.

The pilots were good. Disappointing when planes don't have electrical ports

No complaints - left 20 minutes later than planned but still arrived on time.

Very disappointing that on an international business class flight they would not give me access to the lounge in Boston. They said it was because it was a codeshare flight. International business class should include lounge access regardless of codeshare.

They did not have free WIFI and I was not okay with that!

Flight was on time, clean, etc. Despite connecting to your wi fi I was unable to use your app to watch entertainment.

Awful!!!. I do not recommend United. The flight staff are unhappy and don't attempt to make the passengers feel comfortable or welcome. The food is not edible, and the seats are miserable. My expensive luggage was destroyed, and the ticket prices are too much for the experience.

Even though the incoming flight was delayed by 20 minutes they managed to get us to SFO 15 minutes early.

On time, easy boarding. Anytime you sit in an economy seat, it’s uncomfortable. New plane and the bathrooms were in the galley at the back of the plane which seemed odd.

It was fine for the most part. But the volume on the announcements was way too loud, and the cabin temperature was chilly. We had the hardest landing I've ever experienced- I think it hurt my back, and the tires squealed when we touched down.

Awful. No counter attendants. No dinner offered due to delays.

Why wasn't this flight departure scheduled eith another crew so that it could leave on time? When we arrived in Denver we had so little time between flights we had run to the connecting flight. We should received some credit for the inconvenience.

My flight was 3 hours late, which caused me to miss my connection in Denver. Further, this connecting flight was then Later canceled. This required me to stay another night an hour and a half away, and rent the rental car for an additional Night. I am still waiting for United Airlines to reimburse me for the inconvenience and Expense of having to extend my rental Car for An additional Day. See attached receipt. https://share.icloud.com/photos/0f5ns2AaeIr7w6t_uH1qfPBUg

The forward head smelled putrid and urine soaked, worse than any head in even transoceanic flights. The wifi stopped working after about an hour of flight.

Wifi was good on the flight from DCA to Dallas and terrible on the flight from Dallas to Tucson. The forward head in the flight from Dallas to Tucson was putrid smelling entirely urine soaked. The flight from DCA to Dallas was delayed by almost 30 min with a plane change.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

I had a carry on and a personal bag. I put my personal item under my seat and on way to the seat I put my bag up. I usually close my eyes and rest as I was on call for last 36 hours. I heard very loud announcements that someone needs to identify their bag. Pretty sure it was not mine until the hostess pointed out my jacket details attached to the bag. I asked why she got my bag out. I got berated and did not want to create a scene. But this person needs to be talked to.

Other than being delayed 5.5 hours and having to get a hotel because I missed my connecting flight, it was an okay flight. No in-flight Wi-Fi or entertainment.

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

More options for your flight from Sioux Falls to South Carolina

Complete your trip to South Carolina with a hotel stay or car rental