$165 Find Cheap Flights from Sioux Falls to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Sioux Falls to South Carolina departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Sioux Falls to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Sioux Falls to South Carolina, as well as popular online travel agencies
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Cheap Flights from Sioux Falls to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$273
Myrtle Beach
Myrtle Beach2 stops$261
Greenville
Greenville1 stop$251
Charlotte
Charlotte1 stop$259
Charleston
Charleston1 stop$273
Myrtle Beach
Myrtle Beach2 stops$261
Greenville
Greenville1 stop$251
Charlotte
Charlotte1 stop$259

Book Cheap Sioux Falls to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Sioux Falls to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Sioux Falls to South Carolina

Sat, Apr 4 - Tue, Apr 7
Delta Logo
4:25 pm - 11:19 pm
FSD
-
CLT
5h 54m
1 stop
Delta Logo
6:18 am - 10:21 am
CLT
-
FSD
5h 03m
1 stop
$259Delta
Wed, Mar 25 - Wed, Apr 1
American Airlines Logo
2:06 pm - 11:55 pm
FSD
-
MYR
8h 49m
2 stops
American Airlines Logo
5:10 am - 1:36 pm
MYR
-
FSD
9h 26m
2 stops
$261American Airlines
Fri, May 15 - Tue, May 19
Multiple Airlines Logo
6:11 pm - 10:17 am
FSD
-
CLT
15h 06m
1 stop
Multiple Airlines Logo
7:49 pm - 2:49 pm
CLT
-
FSD
20h 00m
2 stops
$268Multiple Airlines
Fri, May 1 - Thu, May 7
Multiple Airlines Logo
6:11 pm - 9:49 pm
FSD
-
CHS
26h 38m
1 stop
Multiple Airlines Logo
3:26 pm - 5:21 pm
CHS
-
FSD
26h 55m
2 stops
$273Multiple Airlines
Thu, Aug 20 - Tue, Aug 25
United Airlines Logo
7:40 am - 1:50 pm
FSD
-
CLT
5h 10m
1 stop
United Airlines Logo
5:28 pm - 9:38 pm
CLT
-
FSD
5h 10m
1 stop
$279United Airlines
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
3:13 pm - 9:16 pm
FSD
-
CHS
5h 03m
1 stop
United Airlines Logo
4:55 pm - 9:49 pm
CHS
-
FSD
5h 54m
1 stop
$279United Airlines
Sat, Apr 4 - Sat, Apr 11
American Airlines Logo
2:07 pm - 10:48 pm
FSD
-
SAV
7h 41m
1 stop
American Airlines Logo
5:40 am - 11:59 am
SAV
-
FSD
7h 19m
1 stop
$279American Airlines
Sat, Apr 4 - Sat, Apr 11
American Airlines Logo
1:26 pm - 11:59 pm
FSD
-
SAV
9h 33m
2 stops
American Airlines Logo
5:40 am - 11:59 am
SAV
-
FSD
7h 19m
1 stop
$284American Airlines
Fri, Apr 24 - Mon, Apr 27
Multiple Airlines Logo
6:11 pm - 9:41 am
FSD
-
MYR
14h 30m
1 stop
Multiple Airlines Logo
9:58 am - 5:21 pm
MYR
-
FSD
8h 23m
1 stop
$284Multiple Airlines
Thu, Jul 2 - Thu, Jul 9
Delta Logo
8:15 am - 2:06 pm
FSD
-
CLT
4h 51m
1 stop
Delta Logo
6:20 am - 12:28 pm
CLT
-
FSD
7h 08m
1 stop
$291Delta
Booking Insights

KAYAK's insights & trends for Sioux Falls to South Carolina flights

Get data-powered insights and trends into flights from Sioux Falls to South Carolina to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Sioux Falls to South Carolina?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Sioux Falls to South Carolina departing in May.

Good to know

Low seasonFebruary
Cheapest flight$165
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 9% increase in price.
Flight from Sioux Falls to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Sioux Falls to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Sioux Falls to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Sioux Falls to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Sioux Falls to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Sioux Falls to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Sioux Falls to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Sioux Falls to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Sioux Falls to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Sioux Falls to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Sioux Falls to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Sioux Falls to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8237 reviews
8.5Crew
8.1Boarding
7.8Entertainment
7.9Comfort
7.2Food
Airline reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

6.0 GoodAnonymous, Feb 2026
RDU - SEA
Read more Delta reviews

Everything was good except wifi and a leaking drink chiller. The floor was all wet and my bag was soaked. Did not notice until debarking. Have not heard back from Delta. Even though this was leg one of an international flight in first class, they denied access to their Sky Club - very disappointing!

The staff was fine. The plane was extremely tight, and I paid for the wifi and it did not work at all. I was actually going to ask for a refund.

two hour delay and the Delta representative on the PA system was unable to understand

An awesome flight crew. FC seat cushion just doesn’t cut it for a 3+ hour flight.

2+hrs delay without any reason provided and a cramped flight

We waited an hour on the runway to get a gate in Orlando

Flight was delayed by 3-hours and their fix was… complimentary pretzels.

Flight was delayed due to crew being not on time

Flight crew issues delayed my flight by 2 1/2 hours. Causing me to miss my connection.

The staff on board and gate was nice - a welcome change from the usual. We also arrived early, which was a great benefit, given that it takes 30 minutes plus to get bags at SRQ.

We got delayed three hours and nobody thought to have the bathroom fixed while we were sitting waiting to board? took a full hour to have maintenance come and check it off. Had to shut the bathroom down twice so that the pilots could go to the bathroom. Everyone missed their connections.

Flight left on time and we arrived 25 minutes early! There was a gate available when we arrived so early on a busy Sunday afternoon! Flight attendants came around twice with the drinks cart.

Wonderful. Quick boarding. Early departure and we arrived 30 minutes early at our destination. Unfortunately, when you arrive early, there is still a departing aircraft at our gate. We had to park for 30 minutes until the gate was clear. So our early arrival was not really early at the gate. Otherwise it was a quick and smooth flight. Appreciated the efficiency.

Everything was great except for the boarding process. Everyone is lining up all at the same time and it’s hard to tell between the groups as they are way too large.

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

As great a red-eye flight as red-eye flights can be.

Lack of gluten free options in food service. I have Celiac disease and it appears you no longer offer special meals for people with dietary restrictions. I am a frequent flyer traveling into and out of Omaha airport. I have noticed over the course of several months that although our flight typically arrives ahead of schedule (awesome job AA!) - we typically sit on the runway for several minutes waiting for the ground crew to get in place. Not sure if it is a ground crew issue or a gate availability issue (due to construction at this airport). Seems to be more of a ground crew being on time issue.

Arrived early picked up my bag in a few minutes- great trip - thank you

Flight boarded, departed and landed on time. Excellent service from flight attendant in FIRST

Boarding is always an ordeal. Less dogs on flights. I am highly allergic to dogs and cats. Why are there so many animals these days?

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

There was a delay with the plan which cause the flight to leave later and once arrived in Chicago there was another delay and some passengers missed their connecting flights

Massimo, flight attendant was very authentic, attentive - wonderful. Food/wrap was just okay.

Worst experience ever. Flight could not land in Charlotte for what we were told was a ground stop. Had to be diverted to Raleigh to refuel. Strangely during ground stop, our connecting flight had no issue taking off on time causing us to miss our flight. We were told there were no other flights that day to our final destination and that two days out was the next one. The only flights to get us there were from Chicago the next morning. Completely opposite direction but it was a direct flight. So we get flown to Chicago and have to find a hotel in our own dime. The flight in the morning was also delayed. Thankfully only a short time. The non too of all this, our luggage did not arrive by the time we were there. Communication was terrible, through the entire trip. Complete incompetence. Will never fly American again.

I am an AA flyer for a very long time... AA has yet to disappoint.

Flight was delayed. Not much information on when the flight would take off. Eventually we were told it was maintenance. App was not giving updates.

Everything you need to know for your flight from Sioux Falls to South Carolina

Information on your arrival and departure airports