$399 Find Cheap Flights from Spain to Panama

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KAYAK's insights & trends for flights to Panama

Get data-powered insights and trends for flights to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to Panama?

These are the best round-trip prices found by users searching on KAYAK in the last 72 hours.

The cheapest ticket to Panama from Spain found in the last 72 hours was to Panama City, at $944 round-trip. The most popular route is Madrid (MAD) to Panama City (PTY) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $944.

What is the cheapest month to fly from Spain to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Spain to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Spain to Panama is September, when tickets cost $608 (return) on average. On the other hand, the most expensive months are August and December, when the average cost of round-trip tickets is $1,161 and $958 respectively.

How far in advance should I book a flight from Spain to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Spain to Panama, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Which is the cheapest airport to fly into in Panama?

Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Panama is Panama City Tocumen Intl Airport (PTY), with an average flight price of $713.


Good to know

Low seasonMay
High seasonDecember
Cheapest flight$399
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Madrid to Panama City

FAQs for booking flights from Spain to Panama

  • How does KAYAK find such low prices on flights from Spain to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Spain to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Spain to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Spain to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Spain to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Spain to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Spain to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Spain to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Panama?

    Based on KAYAK data, the cheapest day to fly to Panama is Monday where round-trip tickets can be as cheap as $735. On the other hand, the most expensive day to fly is Tuesday, where round-trip prices are $1,024 on average.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $868 on average. Morning departures are around 2% cheaper than evening flights, on average. The most expensive time of day to fly to Panama is generally in the evening, which is peak travel time and where the average cost of a ticket is $887.

Top 3 airlines serving from Spain to Panama

Need help choosing which airline to fly with from Spain to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
IberiaOverall score based on 2700 reviews
7.1Boarding
6.3Food
6.7Comfort
6.6Entertainment
7.6Crew
Airline reviews

Awful. The flight wasn't actually operated by Iberia, but by American Airlines. I was unable to get my boarding pass and as a result missed my connecting flight.

2.0 MediocreAnonymous, Apr 2025MAD - LHR
Read more Iberia reviews

Awful. The flight wasn't actually operated by Iberia, but by American Airlines. I was unable to get my boarding pass and as a result missed my connecting flight.

Very good service from San Jose to Madrid . Ryanair service from Madrid to Brussels 😕

I wish they could put the pre-tsa check on the tickets or global entry.

Couldn’t keep my luggage and had no choice. Ground staff didn’t even bother to explain why.

We upgraded to Business class paying approx. $1,300. Despite the upgrade, we were still required to pay an additional €70 for a checked bag. Furthermore, we were informed that another €70 would have been charged for our carry-on bag, as it was 3kg over the limit. To avoid this, we had to move clothing from the carry-on into the checked bag, which was both inconvenient and frustrating. Given the significant amount paid for the Business Class upgrade, we found this treatment to be quite appalling and disappointing. We expected a higher level of service and consideration for our luggage, and this experience did not meet those expectations.

Great flight, short and good attention. Didn't took any food so can't say thing about it

At Barcelona, you have to get your passports checked before going to the E gates so give yourself time for that. The restaurants around the D and E gates are really limited compared to prior to passport control. On boarding, the gate staff tried to charge me EUR100 for my carryon, saying it was too big. I put it in their ‘measurement box’ and it fit with the top slightly protruding where the handle was. The gate staff then said my bag was ok to carry and put an ‘approved’ tag on my bag. I was bussed to the plane I boarded a ‘Level’ carrier which I had not heard of before. If you booked through a code share like American, you will be served food and alcohol on the plane. They do not provide complimentary ear phones or blankets. The internet was free but only for texting. WhatsApp worked but Spotify did not. Entertainment choice was adequate, movies were old and selection was limited. On arrival at LAX, my checked in bag was damaged as the wheel was broken. I am taking this up with Iberia. Their website and customer service was moderate in terms of user friendliness. You have to have all your documents and prepared to be patient and persistent. Let’s see how this goes. All n all, for the price I paid, I would recommend Level.

Excellent with no delays and according to the time schedule.

Its a bus taking you on and off the plane so if you have big luggage … more muscles needed

Flight LIN MAD. Checkin was fine (but I must admit that being a Platinum member I skip the lines). Security was fine (they have the new machines where you need not take laptops or liquids out). Longe was OK (BA). Boarding was a mess, the boarding gate personnel were rude and some should simply not be in a customer facing position. Flight in itself was fine, usual Iberia European coach. We were on time and actually time to deliver luggage was better than normal for Barajas

They didn't even give us water, everything was sold

They should at least offer water like other airlines, which seems like a humanitarian gesture to me

They gave me an upgrade but charged me for my bag. I felt abused because this had never happened to me before with an upgrade with another airline.

Well. It is a no frills airline. Annoying is that even for the long-haul everything has to be paid for separately. Once you add up the extras the flight is getting to expensive. Then one might as well fly with a legacy carrier which provides far better comfort. Changing flight at MAD airport is a nightmare. The worst airport in the world. Poor signposting, poor passport control, poor security check and long queues. I had 2h transfer time and spend in queues almost 1.5h

All flights with Air Europa you arrive late to the connections of other flights, I missed my train, I had to pay for my train again, the crew are antisocial, you are paying for a service, it is not free, thanks to the travelers they are there, it is the last time I fly with them,

Terrible experience - we won’t be flying with Air Europa again

The crew was not kind , just doing their job but very cold people

The insanely long lines at customs were chaotic and stressful. They also created a lot of stress among passengers. Including fights and threats. The hot food I purchased was cold, barely edible. The check in staff and crew were nice and the pilot good but the overall experience was very disappointing. Passengers were still insulting each other upon arrival.

No frills airlines. Tickets were reasonably priced for a short-term booking. But comfort is a big issue.

It was just okay. They overcharged me for a checked bag because I didn’t know it wasn’t included in the airfare.

A few years ago long flights 6 hours or so used to have video screens and they offered ear phones. The food cart used to come and drinks. Now absolutely nothing. Avianca is as bad as Spirit Airlines. Avianca will now be my last choice when booking my next flight.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

I paid over $200 for seat selection for these flights and I was still stuck on long international flights in seats that do not recline and do not have the head support cushion. At this point basically all airlines have those for all seats, and this really took me by surprise and made me not ever want to travel on Avianca. The Kayak agent who called me for the seat selection (Donovan) was courteous, but it seems the system for this doesn't work. I was offered seat selection, for the $200+, but without being able to see what I was selecting, with no guarantee where I'd be...and then I still ended up in terrible seats. On my way to, and especially after, a very intense business trip, the seat situation really soured my experience.

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

The connection time is too short to pass through customs and once you do clear customs the connecting flight is in another terminal that is not close.

Book cheap flights from Spain to Panama

Recent round-trip flight deals

5/17Sat
1 stopKLM
27h 25mMAD-PTY
6/10Tue
1 stopKLM
14h 35mPTY-MAD
$660
9/11Thu
1 stop
37h 30mMAD-PTY
9/22Mon
1 stop
13h 50mPTY-MAD
$661
10/19Sun
1 stopAvianca
15h 40mMAD-PTY
10/29Wed
1 stopAvianca
13h 16mPTY-MAD
$696
10/19Sun
1 stopAvianca
15h 40mMAD-PTY
10/30Thu
1 stopAvianca
18h 40mPTY-MAD
$698
5/21Wed
2 stopsUnited Airlines
38h 01mMAD-PTY
5/30Fri
2 stopsUnited Airlines
27h 05mPTY-MAD
$699
5/21Wed
1 stopUnited Airlines
15h 41mMAD-PTY
5/30Fri
2 stopsUnited Airlines
23h 30mPTY-MAD
$704
6/19Thu
nonstopAir Europa
10h 35mMAD-PTY
7/12Sat
nonstopAir Europa
9h 50mPTY-MAD
$731
6/14Sat
1 stopAir Europa
13h 50mBCN-PTY
6/21Sat
1 stopAir Europa
13h 10mPTY-BCN
$747
8/25Mon
nonstopIberia
10h 40mMAD-PTY
9/15Mon
nonstopIberia
10h 05mPTY-MAD
$764
6/12Thu
nonstopIberia
11h 05mMAD-PTY
6/23Mon
nonstopIberia
10h 05mPTY-MAD
$850

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Recent one-way flight deals

5/5Mon
nonstopIberia
11h 05mMAD-PTY
$399
5/12Mon
1 stopAir Europa
13h 50mBCN-PTY
$411
5/15Thu
1 stopAir Europa
29h 10mBCN-PTY
$421
5/26Mon
nonstopIberia
11h 05mMAD-PTY
$444
6/11Wed
2 stopsAvianca
18h 05mMAD-PTY
$516
5/30Fri
1 stopAvianca
18h 30mMAD-PTY
$528
6/18Wed
1 stopKLM
14h 30mBCN-PTY
$636
5/26Mon
2 stopsTurkish Airlines
37h 20mMAD-PTY
$776
5/26Mon
2 stopsTurkish Airlines
34h 35mMAD-PTY
$777
7/1Tue
1 stopKLM
28h 10mBCN-PTY
$868

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Last minute flights to Panama

Last minute flight, train and bus deals

5/4Sun
multi-stopUnited Airlines
15h 41mMAD-PTY
5/11Sun
multi-stopUnited Airlines
39h 05mPTY-MAD
$741
5/2Fri
multi-stopUnited Airlines
35h 57mMAD-PTY
5/28Wed
multi-stopUnited Airlines
25h 20mPTY-MAD
$748
5/5Mon
nonstopIberia
11h 05mMAD-PTY
5/19Mon
nonstopIberia
9h 50mPTY-MAD
$770
5/5Mon
multi-stop
18h 45mMAD-PTY
5/19Mon
multi-stop
31h 45mPTY-MAD
$809
5/5Mon
multi-stopUnited Airlines
24h 43mMAD-PTY
5/19Mon
multi-stopUnited Airlines
24h 32mPTY-MAD
$816
5/5Mon
multi-stopUnited Airlines
15h 41mMAD-PTY
5/19Mon
multi-stopUnited Airlines
24h 32mPTY-MAD
$821
5/4Sun
multi-stopUnited Airlines
19h 56mMAD-PTY
5/11Sun
multi-stopUnited Airlines
30h 55mPTY-MAD
$842
5/1Thu
multi-stopAvianca
15h 40mMAD-PTY
5/27Tue
multi-stopAvianca
37h 10mPTY-MAD
$952
5/4Sun
nonstopAir Europa
10h 35mMAD-PTY
5/11Sun
nonstopAir Europa
9h 50mPTY-MAD
$1,061
5/5Mon
multi-stop
21h 47mMAD-PTY
5/17Sat
nonstop
9h 50mPTY-MAD
$1,426

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Everything you need to know for your flight to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

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