$364 Find Cheap Flights from Spain to Panama - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Spain to Panama departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Spain to Panama

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Spain to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Spain to Panama

Sat, Aug 29 - Sun, Sep 13
Delta Logo
3:15 pm - 12:55 pm
BCN
-
PTY
28h 40m
2 stops
Delta Logo
2:23 pm - 12:50 pm
PTY
-
BCN
15h 27m
1 stop
$764Delta
Sat, Sep 12 - Sat, Sep 26
Delta Logo
3:15 pm - 12:58 pm
BCN
-
PTY
28h 43m
2 stops
Delta Logo
2:23 pm - 12:50 pm
PTY
-
BCN
15h 27m
1 stop
$765Delta
Wed, Sep 23 - Wed, Nov 4
Iberia Logo
9:40 am - 7:35 pm
VLC
-
PTY
16h 55m
1 stop
Iberia Logo
6:35 pm - 5:05 pm
PTY
-
VLC
16h 30m
1 stop
$801Iberia
Mon, Sep 7 - Mon, Sep 21
Avianca Logo
11:05 am - 2:15 pm
MAD
-
PTY
34h 10m
1 stop
Avianca Logo
4:25 am - 6:10 am
PTY
-
MAD
18h 45m
1 stop
$809Avianca
Sat, Aug 29 - Mon, Sep 14
Iberia Logo
5:40 pm - 7:35 pm
VLC
-
PTY
32h 55m
1 stop
Iberia Logo
9:05 pm - 12:15 am
PTY
-
VLC
20h 10m
1 stop
$811Iberia
Wed, Sep 2 - Sat, Sep 26
Avianca Logo
8:10 am - 2:15 pm
MAD
-
PTY
13h 05m
1 stop
Avianca Logo
5:55 pm - 12:20 am
PTY
-
MAD
23h 25m
1 stop
$818Avianca
Tue, Sep 22 - Mon, Oct 5
Air Europa Logo
3:05 pm - 6:40 pm
MAD
-
PTY
10h 35mnonstop
Air Europa Logo
8:25 pm - 1:15 pm
PTY
-
MAD
9h 50mnonstop
$822Air Europa
Sun, Sep 6 - Sun, Sep 13
Multiple Airlines Logo
5:15 pm - 7:45 pm
BIO
-
PTY
33h 30m
2 stops
Multiple Airlines Logo
9:55 pm - 10:00 pm
PTY
-
BIO
17h 05m
1 stop
$895Multiple Airlines
Tue, Oct 20 - Mon, Oct 26
Air Europa Logo
8:20 am - 6:40 pm
BIO
-
PTY
17h 20m
1 stop
Air Europa Logo
9:30 pm - 8:05 pm
PTY
-
BIO
16h 35m
1 stop
$908Air Europa
Tue, Aug 4 - Sat, Aug 8
Multiple Airlines Logo
9:05 pm - 2:34 pm
LCG
-
PTY
24h 29m
2 stops
Multiple Airlines Logo
8:25 pm - 8:20 pm
PTY
-
LCG
16h 55m
1 stop
$1,424Multiple Airlines
Booking Insights

KAYAK's insights & trends for flights to Panama

Get data-powered insights and trends for flights to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to Panama?

These are the best round-trip prices found by users searching on KAYAK in the last 5 days.

The cheapest ticket to Panama from Spain found in the last 5 days was to Panama City, at $811 round-trip. The most popular route is Madrid (MAD) to Panama City (PTY) and the cheapest round-trip airline ticket found on this route in the last 5 days was $811.

What is the cheapest month to fly from Spain to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Spain to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Spain to Panama is September, when tickets cost $378 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $773 and $763 respectively.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Spain to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $956 on average. Morning departures are around 4% cheaper than evening flights, on average. The most expensive time of day to fly to Panama is generally in the evening, which is peak travel time and where the average cost of a ticket is $996.

How far in advance should I book a flight from Spain to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Spain to Panama, you should book around 3 weeks before departure, which saves you about 12% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Which is the cheapest airport to fly into in Panama?

Prices will differ depending on the departure airport, but generally, the cheapest airport to fly to in Panama is Panama City Tocumen Intl Airport (PTY), with an average flight price of $938.

Good to know

Low season

May

Cheapest flight

$364
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 23% increase in price.
Flight from Madrid to Panama City

FAQs for booking flights from Spain to Panama

  • How does KAYAK find such low prices on flights from Spain to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Spain to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Spain to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Spain to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Spain to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Spain to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Spain to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Spain to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Panama?

    Based on KAYAK data, the cheapest day to fly to Panama is Wednesday where round-trip tickets can be as cheap as $758. On the other hand, the most expensive day to fly is Tuesday, where round-trip prices are $1,201 on average.

Reviews of the top 4 airlines serving from Spain to Panama

 
Need help choosing which airline to fly with from Spain to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Air FranceOverall score based on 1626 reviews
7.0Food
8.2Crew
7.5Boarding
7.4Comfort
7.0Entertainment
Airline reviews

I love Air France. This was another great experience despite a slight delay in the departure. The time was made up on flight. I would take AirFrance again when traveling to the far East. Merci beaucoup.

10.0 ExcellentAlvaro, Jun 2026
MAD - CDG
Read more Air France reviews

I love Air France. This was another great experience despite a slight delay in the departure. The time was made up on flight. I would take AirFrance again when traveling to the far East. Merci beaucoup.

I don't understand the concept of paying to get your personal luggage onboard and then asked to check it in.... either sell the space or don't, its a hassle to carry those all through the airport just to make a check in at the last minute.

Much better than the major US Carriers especially in Biz Class.

I wish that the meal included a vegetable or even a salad instead of couscous! Why serve chicken with rice AND couscous? Service was good overall though a bit lacking in friendliness. Usually on air france I've been offered a glass of champagne before dinner, wine with dinner, and a digestif after dinner. We were only offered wine this time!

It was not Air France but Air Europa. But confusion over our checked luggage. Whether it was checked all the way to Tenerife or not. It was not. Had to line up again in Departures. At least our Sky Priority was honoured. Flight was fine.

They again did not offer any functioning WiFi in the transatlantic crossing.

The check in was horrible. I stood in line for 1 hour to check in with an Air France ticket. Then I was told I had to go to Delta counter onstead to check in instead. It made no sense.

Old cabine without flat bed in business for a 12 hour flight is not acceptable

Excellent apart from transport to actual plane 10 minutes from the actual gate , walking out in the tarmac in the rain and having to climb stairs to enter while holding luggage.

Everything went smoothly with Air France. There was a delay in departure which seemed to relate to the immigration services being short staffed.

There are often trade-offs involved with flying cheaper airlines. With Air Europa, their crowd control is terrible--the line at check-in in Madrid was absolutely hideous 3 hours before departure. These 787 "Dreamliners" are cheaply-made and uncomfortable. And disembarking at JFK was horrid...it was 11 p.m., yet we were force to deal with those off-site shuttle buses, presumably because Air Europa doesn't want to pay what it costs for an actual gate. But as usual, the worst aspect of Air Europa flights are tones fellow passengers: unruly and oblivious to such concepts as personal space. The crew was, on the other hand, lovely.

The flight was long but everything went well. Crew was helpful and very attentive. Food was good and the entertainment options were many.

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

We experienced a delay of almost two hours before takeoff. For a flight of more than 10 hours, sitting on the runway for two hours is quite exhausting. The airline did nothing to attend to the passengers during that time. We were not given any courtesy drinks or snacks—only the bare minimum during the flight. The crew seemed very apologetic, but apparently they have restrictions imposed by the airline, because despite their friendliness, they provided strictly what was necessary and, of course, everything else was for sale. However, after a two-hour delay, one would expect at least complimentary beverages. In addition to this, the space between the rows of seats is inhumanely narrow. Air Europa should review this for such long flights and be a bit more considerate and humane with its customers.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

Boarded in group three at Barcelona, which meant going from a gate outside onto a bus to ride across the airport to a plane waiting on the tarmac. When we arrived at the plane, crew behavior told us something was wrong. Bus driver would not let us off for almost twenty minutes, despite being crammed shoulder to shoulder. Eventually, we got onto the plane, but were then told that someone “forgot” to refuel the plane and the truck to do so had not arrived. We departed late enough that we missed our connecting train in NYC, which was the last train of the evening, so we had to stay awake all night in the passenger waiting area of Amtrak’s Penn Station, which was almost impossible to get to because the station was now closing, as it was after midnight. We had to haul four suitcases a few blocks on city streets in the rain to get to the one remaining open entrance to Penn Station. We ended up being up for 36 hours straight because someone couldn’t do their job. Never, ever again would I fly this airline.

All four segments of my trip on Iberia were late for various reasons. No apparent effort to stay on schedule. Never flying Iberia again.

The flight from Madrid to Boston was awful. Without prior warning, I was seated in the row in front of an exit row where my seat did not recline. The person in front of me reclined, reducing my already tiny space further. This was the WORST flight I've ever had.

Without any prior warning, I was seated in a row just in front of an exit row (27F), and I had no idea that my seat would not recline. However, the person in front of me did recline her seat, reducing my space. And because I could't recline to regain some space, it was my WORST flight ever.

Overall it was okay. Just the lost baggage and how they are handling it

Puddle-hopper. Quick-ish flight. Don’t expect to have much/any in-flight entertainment (movies/TV, etc).

Worst flight I ever experienced, what was supposed to a 7 hour flight ended being 13 hours on a plane with no ac and the worst cabin I have ever seen. Never again.

Horrible seat at the back. Crew was very kind. Packed plane. Wordy pilot bragging about Iberia being punctual when many of us came from Alicante flight that was delayed an hour and many lost connection and we lost our luggage. Still waiting for it

I’m an Iberia fan but this time They dropped the ball. I went from ALC to MAD to LHR. Boarding in ALC was by group… to get you in a bus. Then we sat for almost an hour when most people had connections. When we landed in Madrid we did so and they put us in another bus almost like if they wanted to make people lose their connection. We made ours by the skin of our teeth but our luggage did not. And on top of this we had to listen to the pilot bragging about Iberia being punctual. To be true we made it on time to LHR but we are Still waiting for our luggage

Worst flight in years.. is not easy to flight 11 hours without entertainment onboard and the crew was not empathetic about it or even gave an apology for the inconvenience. Poor treatment to the passengers, and some responses where roughly given.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

The connection time is too short to pass through customs and once you do clear customs the connecting flight is in another terminal that is not close.

Same experience, very poor food, drinks or entertainment while flying. There are some products offered to buy but only using debit or credit cards . No friendly for seniors or people without cards.

It’s very nice, the only thing is that we have to purchase food.

Awful. I checked in online and there was no option to pay for baggage, at the airport when I checked in my baggage was received and Iwas not charged. When I got to LA during the boarding process I was told I didn't pay for baggage, the crew resolved I was let in the plane. When I got to my final destination my baggage was not there. It took me two days to receive my baggage. Bad service ever!

Discomfort has become a feature in Avianca flights. That isn’t terrible on short, local flights (most of them 1-2 Hrs)… but a 7-Hr flight with no water, no coffeee, no nothing (unless you buy it) is just not right. Uncomfortable seats, almost inhuman space between chairs, in long-haul flights needs to be reviewed by airline. And unavailable entertainment system doesn’t help either. Flight was safe and on-time, which isn’t easy to achieve. But all other features aren’t features: they’re a modern way of torture. Avianca really needs to up their game, or bluntly declare: we’re an ultra low-cost airline, and fees will drop accordingly.

At least free water in all flights Beverages are desired in international flights Luggage damages need be refund!

Horrible service. Flight was delayed and the don't even offer eatwr

Everything you need to know for your flight to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.