Orlando Hotels in South Orange

Find a home away from home at our Hampton Inn & Suites Orlando/Downtown South-Medical Center. This welcoming hotel is within walking distance to Orlando Regional Medical Center, UF Health Cancer Center and Arnold Palmer Hospital for Children. Just a few blocks from the Amtrak line, it’s easy to get around town from our hotel. Make your stay easy with free hot breakfast every morning or if you’re pressed for time, grab one of our Hampton’s On the Run™ Breakfast Bags, available Monday through Friday. All our rooms feature two queen or one king-sized Hampton clean and fresh bed® along with a lap desk and free WiFi. Unwind with your favorite shows on the 39-inch HDTV. Book one of our 35 suites for more space, a separate living area and a sleeper sofa. Take a break under the Florida sun in our heated, outdoor pool. Continue your workout plan in our fitness center with a treadmill, elliptical, free weights and weight machines. Host an event in our expanded 1,800 sq. ft. space for up to 85 people. Utilize the LCD projector with screen, conference phone and free WiFi for a successful meeting or training seminar. Plan a fun Orlando break with the friendly service and local advice from our hotel staff.