ANF - SCL

Find cheap flights from Antofagasta to Santiago

1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Antofagasta to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Antofagasta to Santiago, as well as popular online travel agencies
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Expert advice
Booking Insights
Flight Deals

Cheap Flights from Antofagasta to Santiago (ANF-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Antofagasta to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Antofagasta to Santiago

Multiple Airlines Logo
ANF-SCL
687 mimulti-stop
Multiple Airlines Logo
SCL-ANF
687 mimulti-stop
Multiple Airlines
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Expert advice

Expert advice for your flight from Antofagasta to Santiago

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Sky Airline

Sky Airline's Zero fare includes a personal item and random seat assignment, ideal for light travelers.


Sky Airline's Plus fare allows a personal item, carry-on, and checked bag up to 50 pounds.

Read more about Sky Airlineby Daniel Scheffler
LATAM Airlines

LATAM's Premium Economy offers priority check-in, lounge access, and a blocked middle seat for comfort.


LATAM's Wi-Fi is available on narrowbody flights in Chile, offering free messaging for loyalty members.

Read more about LATAM Airlinesby Marisa Garcia
Our travel experts
Daniel Scheffler

Daniel Scheffler

Expert on Sky Airline

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more
Marisa Garcia

Marisa Garcia

Expert on LATAM Airlines

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Booking Insights

KAYAK's insights & trends for Antofagasta to Santiago flights

Get data-powered insights and trends into flights from Antofagasta to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Antofagasta to Santiago?

The average price of all round-trip flights from Antofagasta to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Antofagasta to Santiago, you should consider leaving on a Saturday and avoid Mondays if you are looking for the best rates. For your return to Antofagasta, you’ll find the best rates on Fridays and the most expensive ones on Mondays.

What is the cheapest month to fly from Antofagasta to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Antofagasta to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Antofagasta to Santiago is January, where tickets cost $62 (return) on average. On the other hand, the most expensive months are November and June, where the average cost of round-trip tickets is $77 and $73 respectively.

Can I save money by flying with a layover from Antofagasta to Santiago?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $59, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Antofagasta to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Antofagasta to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Antofagasta to Santiago, you should book around 6 weeks before departure, which saves you about 32% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Find deals

Good to know

Low seasonJune
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 11% increase in price.

When to book flights from Antofagasta to Santiago

Are your dates flexible? Find out the best times to travel from Antofagasta to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Antofagasta to Santiago

  • Do I need a passport to fly between Antofagasta and Santiago?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from Antofagasta to Santiago?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Antofagasta to Santiago flight route.

  • Which airline alliances offer flights from Antofagasta to Santiago?

    oneworld, and SkyTeam are the airline alliances operating flights between Antofagasta and Santiago, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Antofagasta to Santiago?

    There are nonstop flights from Antofagasta to Santiago on a daily basis.

  • How does KAYAK find such low prices on flights from Antofagasta to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Antofagasta to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Antofagasta to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Antofagasta is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Antofagasta to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Antofagasta with another airline. Booking your flights between Antofagasta and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Antofagasta to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Antofagasta up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Antofagasta to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $90 or less one-way and $57 or less round-trip.

Prefer to fly direct from Antofagasta to Santiago?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Antofagasta Cerro Moreno to Santiago Arturo Merino Benitez.
Find which airlines fly direct from Antofagasta Cerro Moreno Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Antofagasta Cerro Moreno to Santiago Arturo Merino Benitez

Monday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Tuesday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Wednesday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Thursday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Friday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Saturday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Sunday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno

Monday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Tuesday

American Airlines, Iberia, JetSMART, +3 more

American Airlines, Iberia, +4 more

Wednesday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Thursday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Friday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Saturday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

Sunday

American Airlines, Delta, Iberia, +4 more

American Airlines, Delta, +5 more

See more direct flights

Reviews of the top airline flying from Antofagasta to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Antofagasta to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Antofagasta to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1840 reviews
8.0Crew
7.6Boarding
6.7Food
7.4Comfort
7.0Entertainment
Airline reviews

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

2.0 MediocreAnonymous, Aug 2025GIG - GRU
Read more LATAM Airlines reviews

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Lost ,y connection due to a mechanical delay, huge line to get new connection and vouchers

It’s a delta flight operated by LATAM. The whole ticket sale is a mess, delta changed my flight but didn’t update it in LATAM system, I couldn’t get my boarding pass, it took me hours to resolve this issue with delta. I had to change my travel plan. No apology from Delta even though it’s their fault.

The boarding and new bag drop-off process was confusing and causing massive delays.

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

Everything you need to know for your flight from Antofagasta to Santiago

Information on your arrival and departure airports

Antofagasta (ANF)
Santiago (SCL)

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