ANF - SCL

$23 Find Cheap Flights from Antofagasta to Santiago - Compare and Save

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Everything you should know

Cheapest round-trip
$44
Typical prices: $84-$150
JetSMART
Wed 11/7Sun 11/11
ANF - SCL • Non-stop
Cheapest non-stop
$44
Typical prices: $84-$149
JetSMART
Wed 11/7Sun 11/11
ANF - SCL • Non-stop
Nonstop flights
You can fly direct with LATAM Airlines, JetSMART and Sky Airline. Average duration is 1h 53m
Direct flights
+1
Direct flights
+1
Avoid delays
Most punctual • 91% on-time
Best time • Fewest delays
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 19 weeks in advance save around 56% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 14% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $207 (round-trip)
Shortest trip • 4h 50m (one-way)
Insights
Insights
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Flight Deals
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Expert advice
Flight Deals

Cheap Flights from Antofagasta to Santiago (ANF-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Antofagasta to Santiago

Sat, Nov 7 - Wed, Nov 11
JetSMART Logo
8:55 pm - 10:50 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 55mnonstop
JetSMART Logo
5:16 am - 7:20 amSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$44JetSMART
Wed, Mar 10 - Wed, Mar 17
Multiple Airlines Logo
9:44 pm - 11:36 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 52mnonstop
Multiple Airlines Logo
6:05 am - 8:09 amSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$46Multiple Airlines
Sun, Nov 1 - Wed, Nov 18
JetSMART Logo
10:59 pm - 12:51 amANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 52mnonstop
JetSMART Logo
10:34 am - 12:38 pmSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$47JetSMART
Fri, Apr 9 - Sun, Apr 11
Sky Airline Logo
1:44 pm - 4:59 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
3h 15m1 stop La Serena La Florida
Sky Airline Logo
4:10 pm - 7:22 pmSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
3h 12m1 stop La Serena La Florida
$48Sky Airline
Sun, Nov 1 - Mon, Nov 16
JetSMART Logo
10:59 pm - 12:51 amANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 52mnonstop
JetSMART Logo
4:36 am - 6:40 amSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$51JetSMART
Wed, Mar 10 - Wed, Mar 17
Sky Airline Logo
3:58 pm - 5:39 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
25h 41m1 stop La Serena La Florida
Sky Airline Logo
6:55 pm - 8:53 pmSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
1h 58mnonstop
$55Sky Airline
Wed, Mar 10 - Wed, Mar 17
Multiple Airlines Logo
9:44 pm - 11:36 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 52mnonstop
Multiple Airlines Logo
6:05 am - 8:09 amSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$61Multiple Airlines
Wed, Nov 4 - Wed, Nov 11
Multiple Airlines Logo
8:21 pm - 10:15 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 54mnonstop
Multiple Airlines Logo
5:16 am - 7:20 amSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$62Multiple Airlines
Tue, Oct 27 - Sat, Nov 7
JetSMART Logo
8:08 am - 10:05 amANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
1h 57mnonstop
JetSMART Logo
6:05 am - 8:09 amSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
2h 04mnonstop
$63JetSMART
Mon, Nov 2 - Fri, Nov 6
Sky Airline Logo
2:30 pm - 5:33 pmANF  Antofagasta Cerro Moreno-SCL Santiago Arturo Merino Benitez
3h 03m1 stop La Serena La Florida
Sky Airline Logo
9:36 am - 1:00 pmSCL  Santiago Arturo Merino Benitez-ANF Antofagasta Cerro Moreno
3h 24m1 stop La Serena La Florida
$64Sky Airline
Booking Insights

Price, demand and travel trends for Antofagasta to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Antofagasta to Santiago?

Round-trip flights from Antofagasta to Santiago typically range from $84 to $150. The lowest price found in the past 5 days was $44, on JetSMART.

What's the cheapest day of the week to fly from Antofagasta to Santiago?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Antofagasta to Santiago. It’s 16% cheaper than the average day, while Thursday is the most expensive, with prices 16% higher.

What’s the cheapest month to fly from Antofagasta to Santiago?

•September is the cheapest month to fly from Antofagasta to Santiago at $92 round-trip.
•February ($142) and December ($122) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 54% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Antofagasta to Santiago the cheapest?

Flights from Antofagasta to Santiago are cheapest 19 weeks before departure. Booking in this window typically costs about 56% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Expert advice

Expert advice for your flight from Antofagasta to Santiago

 
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on LATAM Airlines

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Daniel Scheffler

Daniel Scheffler

Expert on Sky Airline

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Key details for Antofagasta to Santiago flights

Low season

July

Cheapest flight

$23
Beat the crowds with an average 24% drop in travelers.
The most popular month to fly with an average 22% increase in travelers.
One-way flight from Antofagasta to Santiago

When to book flights from Antofagasta to Santiago

Are your dates flexible? Find out the best times to travel from Antofagasta to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Antofagasta to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from Antofagasta to Santiago?

    These are the earliest and latest flight times available from Antofagasta to Santiago:

    • Earliest: departs at 12:09 am and lands at 2:02 am
    • Latest: departs at 11:59 pm and lands at 1:52 am.

    The flight takes about 1h 53m.

  • What cabin classes can I book on flights from Antofagasta to Santiago?

    Only Economy Class is available on flights from Antofagasta to Santiago.

  • How long is a flight from Antofagasta to Santiago?

    A nonstop flight from Antofagasta to Santiago takes 1h 53m, covering 687 miles.

  • Do I need a passport to fly from Antofagasta to Santiago?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Antofagasta to Santiago flight?

    Round-trip flights from Antofagasta to Santiago range from $84 to $150, with an average of $107 over the past 12 months. Anything below $84 counts as a good deal.

  • How expensive are last-minute Antofagasta to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 40% above the $107 route average. Book 19 weeks before departure for the lowest fares.

  • How much can I save by taking a layover when flying from Antofagasta to Santiago?

    On this route, nonstop flights are cheaper than layover options on average. Nonstop fares average $107 round-trip, compared to $207 via a layover through Concepción Carriel Sur (CCP).

  • How does on-time performance compare across airlines flying from Antofagasta to Santiago?

    Sky Airline is slightly above the route average for timely arrivals, while LATAM Airlines has a lower on-time arrival rate. On-time arrival rates on Antofagasta to Santiago flights are:

    • Sky Airline: 91% on time
    • LATAM Airlines: 89% on time
    • JetSMART: 86% on time

    Overall, flights on this route are punctual 89% of the time on average.

  • What is the standard checked-bag allowance on flights from Antofagasta to Santiago?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $16–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Antofagasta to Santiago?

    The Airbus A320-100/200 family is used most often on this route, operated mainly by LATAM Airlines and JetSMART. Other aircraft seen on the route include Airbus A321-100/200 variants.

  • How are flight departures from Antofagasta to Santiago spread across the day?

    Morning is the busiest departure period on Antofagasta to Santiago flights, with 30% of flights leaving in that window. Evening departures account for 29%, night flights for 23%, and afternoon flights for 18%.

  • How are flight prices from Antofagasta to Santiago looking right now?

    One-way fares from Antofagasta to Santiago are currently lower than usual. Average one-way flight prices are about $38, which is 38% below the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Antofagasta to Santiago?

    Flights from Antofagasta to Santiago usually depart from Antofagasta Cerro Moreno (ANF) and arrive at Santiago Arturo Merino Benitez (SCL).

  • What time of day has the fewest delays on flights from Antofagasta to Santiago?

    Morning flights have the fewest delays on this route, while evening departures tend to have the most.

  • At what point is a flight considered delayed from Antofagasta to Santiago?

    A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Antofagasta to Santiago route, 11% of flights were delayed in the past 3 months, with delays averaging 1h 41m.

  • Which airports do connecting flights from Antofagasta to Santiago pass through?

    Connecting flights from Antofagasta to Santiago most commonly pass through:

    • La Serena La Florida (LSC) - 95% of one-stop connections
    • Concepción Carriel Sur (CCP) - 5% of one-stop connections

  • Can I save money by using flexible dates for flights from Antofagasta to Santiago?

    Yes. Flexible dates can save you up to 28% on flights from Antofagasta to Santiago. Monday is the cheapest departure day at $90 round-trip on average, while Thursday is the most expensive at $125, a difference of $35.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from Antofagasta to Santiago?

    3 airlines operate flights between Antofagasta and Santiago. The airlines offering nonstop flights on this route include:

    • LATAM Airlines
    • JetSMART
    • Sky Airline

  • How much time can I save by choosing a different layover airport from Antofagasta to Santiago?

    Flying via Concepción Carriel Sur (CCP) gives the shortest average 1-stop total travel time at 4h 45m, compared with 4h 50m via La Serena La Florida (LSC).

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

  • Which airlines offer extra legroom and free seat selection on Antofagasta to Santiago flights?

    Among airlines operating Antofagasta to Santiago flights:

    • JetSMART: offers free seat selection
    • Sky Airline: offers free seat selection
    • LATAM Airlines: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on Antofagasta to Santiago flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • JetSMART: a cabin bag and a checked bag in Economy Class
    • Sky Airline: a cabin bag and a checked bag in Economy Class
    • LATAM Airlines: a cabin bag and a checked bag in Economy Class

    Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.

Your guide to booking Antofagasta to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure and avoid flying on Thursday. On this route, Monday flights average $90, about $35 less than Thursday fares (28% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 19 weeks before you fly. On this route, that window historically saves about 56% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Antofagasta to Santiago trip for September. Fares historically average $92 round-trip in that month - typically $50 less than the most expensive month, which is February (based on the last 12 months).
  • For the best chance of arriving on time, fly with Sky Airline. Over the past three months, 91% of Sky Airline flights from Antofagasta to Santiago arrived on time, slightly above the route average of 89%. When flights on this route arrive late, they're delayed by an average of 1h 41m, so choosing an airline with strong on-time performance can make a difference if you're on a tight schedule.
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

Prefer to fly direct from Antofagasta to Santiago?

 
Find which airlines fly direct from Antofagasta Cerro Moreno Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Antofagasta Cerro Moreno to Santiago Arturo Merino Benitez

Monday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Tuesday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Wednesday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Thursday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Friday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Saturday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Sunday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno

Monday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Tuesday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Wednesday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Thursday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Friday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Saturday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

Sunday

JetSMART,LATAM Airlines,Sky Airline

JetSMART,LATAM Airlines, +1 more

See more direct flights

More options for your flight from Antofagasta to Santiago

Complete your trip to Santiago with a hotel stay or car rental