$125 Find Cheap Flights from Boston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Boston to South America departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Boston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$422
Bogotá
Bogotá1 stop$384
Medellín
Medellín1 stop$294
Buenos Aires
Buenos Aires1 stop$761
Sao Paulo
Sao Paulo1 stop$486
Rio de Janeiro
Rio de Janeiro1 stop$543
Santiago
Santiago2 stops$516
Cartagena
Cartagena1 stop$232
Quito
Quito1 stop$305
Guayaquil
Guayaquil1 stop$260
Cali
Cali1 stop$289
Cusco
Cusco2 stops$533
Georgetown
Georgetown1 stop$422
Pereira
Pereira2 stops$418
Montevideo
Montevideo1 stop$809
Barranquilla
Barranquilla1 stop$302
Santa Marta
Santa Marta2 stops$491
Asuncion
Asuncion2 stops$684
Lima
Lima1 stop$422
Bogotá
Bogotá1 stop$384
Medellín
Medellín1 stop$294
Buenos Aires
Buenos Aires1 stop$761
Sao Paulo
Sao Paulo1 stop$486
Rio de Janeiro
Rio de Janeiro1 stop$543
Santiago
Santiago2 stops$516
Cartagena
Cartagena1 stop$232
Quito
Quito1 stop$305
Guayaquil
Guayaquil1 stop$260
Cali
Cali1 stop$289
Cusco
Cusco2 stops$533
Georgetown
Georgetown1 stop$422
Pereira
Pereira2 stops$418
Montevideo
Montevideo1 stop$809
Barranquilla
Barranquilla1 stop$302
Santa Marta
Santa Marta2 stops$491
Asuncion
Asuncion2 stops$684

Book Cheap Boston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Boston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Boston to South America

Wed, Jan 28 - Sat, Feb 7
Spirit Airlines Logo
5:34 am - 2:15 pm
BOS
-
MDE
8h 41m1 stop
Spirit Airlines Logo
3:15 pm - 11:57 pm
MDE
-
BOS
8h 42m1 stop
$294Spirit Airlines
Wed, Jan 28 - Thu, Feb 5
Spirit Airlines Logo
5:34 am - 2:15 pm
BOS
-
MDE
8h 41m1 stop
Spirit Airlines Logo
3:15 pm - 11:57 pm
MDE
-
BOS
8h 42m1 stop
$295Spirit Airlines
Sat, Feb 28 - Sun, Mar 8
Copa Airlines Logo
7:31 am - 4:59 pm
BOS
-
MDE
9h 28m1 stop
Copa Airlines Logo
10:46 am - 11:10 pm
MDE
-
BOS
11h 24m1 stop
$307Copa Airlines
Sat, Jan 31 - Sun, Feb 8
Copa Airlines Logo
7:31 am - 10:48 pm
BOS
-
MDE
15h 17m1 stop
Copa Airlines Logo
12:42 pm - 10:03 pm
MDE
-
BOS
9h 21m1 stop
$310Copa Airlines
Fri, Mar 6 - Fri, Mar 13
LATAM Airlines Logo
7:59 pm - 4:45 pm
BOS
-
BOG
20h 46m1 stop
LATAM Airlines Logo
10:55 am - 1:13 am
BOG
-
BOS
13h 18m2 stops
$386LATAM Airlines
Thu, Jan 22 - Thu, Jan 29
LATAM Airlines Logo
11:12 am - 7:30 pm
BOS
-
BOG
8h 18m1 stop
LATAM Airlines Logo
9:00 am - 6:54 pm
BOG
-
BOS
9h 54m1 stop
$389LATAM Airlines
Sun, Apr 26 - Mon, May 11
Avianca Logo
4:50 pm - 2:10 am
BOS
-
GRU
32h 20m2 stops
Avianca Logo
4:10 am - 7:15 am
GRU
-
BOS
28h 05m1 stop
$489Avianca
Sun, Apr 26 - Fri, May 8
Avianca Logo
4:50 pm - 12:40 am
BOS
-
GRU
30h 50m2 stops
Avianca Logo
7:20 am - 7:15 am
GRU
-
BOS
24h 55m1 stop
$490Avianca
Mon, Mar 2 - Sun, Mar 15
American Airlines Logo
3:49 pm - 6:05 am
BOS
-
GRU
12h 16m1 stop
American Airlines Logo
10:35 pm - 11:25 am
GRU
-
BOS
13h 50m1 stop
$494American Airlines
Sun, Mar 1 - Mon, Mar 9
American Airlines Logo
3:49 pm - 7:00 pm
BOS
-
VCP
25h 11m2 stops
American Airlines Logo
7:40 pm - 5:29 pm
VCP
-
BOS
22h 49m2 stops
$513American Airlines
Booking Insights

KAYAK's insights & trends for Boston to South America flights

Get data-powered insights and trends into flights from Boston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Boston to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Boston found in the last 72 hours was to Bogotá, at $262 round-trip. The most popular route is from Boston (BOS) to Sao Paulo Guarulhos Intl Airport (GRU), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $435.

Can I save money by flying with a layover from Boston to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $684, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Boston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Boston to South America is September, when tickets cost $528 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $849 and $708 respectively.

How far in advance should I book a flight from Boston to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Boston to South America, you should book around 2 weeks before departure, which saves you about 7% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$125
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 32% increase in price.
Flight from Boston to Medellín Jose Maria Cordova Intl

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Boston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Boston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Boston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Boston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Boston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Boston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Boston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Boston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Boston to South America

 
Need help choosing which airline to fly with from Boston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8034 reviews
7.2Food
7.9Comfort
7.8Entertainment
8.5Crew
8.1Boarding
Airline reviews

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

8.0 ExcellentG, Jan 2026
FLL - ATL
Read more Delta reviews

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

Air travel sucks. It continues to be awful for all airlines. No shame on delta alone.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Flight was late from Newark to Atlanta, I asked flight attendant to please let my family of 3 out first when we landed to Atlanta because we were late for our connecting flight to Quito. She didn't and we were late for 5 minutes we couldn't board the plane and spend hours trying to get another flight with customer service for the next day.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Late delayed flight delays boarding and delays leaving and delays on arrival too. Cramped plane no room no food.

DTW line is too long. The flights from DTW to BWI are always delayed for unknown reasons.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

This flight was no comparison to our prior flight. I'm thinking it all has to do with the age of the aircraft.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Bags took over and hour to come out. Delays due to wind caused rebooking.

The flight was good. We had to spend almost an hour on the tarmac when we arrived in Dallas. Waiting for a gate. What’s the point of arriving early if you have no gate to park at?

Lower WiFi prices; allow us to see our flight on a map; more variety of drink choices.

So excited very proud first of all I wanna thank kayak all updates very professional and fast alart And amazing cabin crew so nice to me they deserve big salute

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

We experienced gate changes and a long delay. My seat was dirty when I boarded and I had to use wipes to clean it myself. There was an unpleasant and overpowering cleaning product scent on the plane as well that lingered through the flight.

Seats were much more cramped then on the 737. Narrower and rows closer together. Flight was absolutely packed and the plugs under the seats didn't work. Was forced to check my bag even though previous flight had no issue with it.

Good food & refreshment. The seats and entrainment screens are modern compared to others. The staff though pleasant serve and attend to passengers based on nationality. Some get served first others last regardless of their seating positions.

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Everything you need to know for your flight to South America

Information on your arrival and departure airports