$104 Find Cheap Flights from Boston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Boston to South America departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from Boston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$418
Bogotá
Bogotá1 stop$295
Medellín
Medellín1 stop$313
Buenos Aires
Buenos Aires2 stops$733
Sao Paulo
Sao Paulo1 stop$533
Rio de Janeiro
Rio de Janeiro1 stop$660
Santiago
Santiago1 stop$614
Cartagena
Cartagena1 stop$318
Quito
Quito1 stop$358
Guayaquil
Guayaquil1 stop$301
Cali
Cali1 stop$396
Cusco
Cusco2 stops$519
Georgetown
Georgetown1 stop$466
Pereira
Pereira1 stop$445
Barranquilla
Barranquilla1 stop$302
Montevideo
Montevideo1 stop$780
Santa Marta
Santa Marta1 stop$405
Asuncion
Asuncion1 stop$641
Lima
Lima1 stop$418
Bogotá
Bogotá1 stop$295
Medellín
Medellín1 stop$313
Buenos Aires
Buenos Aires2 stops$733
Sao Paulo
Sao Paulo1 stop$533
Rio de Janeiro
Rio de Janeiro1 stop$660
Santiago
Santiago1 stop$614
Cartagena
Cartagena1 stop$318
Quito
Quito1 stop$358
Guayaquil
Guayaquil1 stop$301
Cali
Cali1 stop$396
Cusco
Cusco2 stops$519
Georgetown
Georgetown1 stop$466
Pereira
Pereira1 stop$445
Barranquilla
Barranquilla1 stop$302
Montevideo
Montevideo1 stop$780
Santa Marta
Santa Marta1 stop$405
Asuncion
Asuncion1 stop$641

Book Cheap Boston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Boston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Boston to South America

Tue, Apr 14 - Mon, Apr 20
Spirit Airlines Logo
5:45 am - 1:11 pm
BOS
-
BOG
8h 26m
1 stop
Spirit Airlines Logo
2:07 pm - 10:15 am
BOG
-
BOS
19h 08m
1 stop
$295Spirit Airlines
Tue, Apr 14 - Mon, Apr 20
Spirit Airlines Logo
5:45 am - 1:11 pm
BOS
-
BOG
8h 26m
1 stop
Spirit Airlines Logo
2:07 pm - 10:15 am
BOG
-
BOS
19h 08m
1 stop
$304Spirit Airlines
Sat, Apr 25 - Sat, May 2
Spirit Airlines Logo
5:55 am - 1:12 pm
BOS
-
BOG
8h 17m
1 stop
Spirit Airlines Logo
2:07 pm - 7:47 am
BOG
-
BOS
16h 40m
2 stops
$310Spirit Airlines
Wed, May 6 - Wed, May 13
Copa Airlines Logo
4:00 pm - 8:05 am
BOS
-
CTG
17h 05m
1 stop
Copa Airlines Logo
12:00 pm - 11:08 pm
CTG
-
BOS
10h 08m
1 stop
$329Copa Airlines
Thu, Apr 9 - Tue, Apr 14
Copa Airlines Logo
3:46 pm - 11:00 pm
BOS
-
CTG
8h 14m
1 stop
Copa Airlines Logo
6:20 am - 11:09 pm
CTG
-
BOS
15h 49m
1 stop
$344Copa Airlines
Wed, May 6 - Wed, May 13
American Airlines Logo
6:53 pm - 12:09 pm
BOS
-
CTG
18h 16m
2 stops
American Airlines Logo
1:25 pm - 10:01 am
CTG
-
BOS
19h 36m
2 stops
$346American Airlines
Thu, May 28 - Sat, Jun 6
American Airlines Logo
1:45 pm - 2:13 pm
BOS
-
CTG
25h 28m
1 stop
American Airlines Logo
1:35 pm - 11:37 pm
CTG
-
BOS
9h 02m
1 stop
$350American Airlines
Mon, May 4 - Thu, May 14
LATAM Airlines Logo
3:24 pm - 5:00 am
BOS
-
LIM
14h 36m
1 stop
LATAM Airlines Logo
8:15 am - 11:31 pm
LIM
-
BOS
14h 16m
1 stop
$439LATAM Airlines
Tue, Jun 16 - Sun, Jun 21
LATAM Airlines Logo
7:05 am - 2:30 pm
BOS
-
CNF
30h 25m
2 stops
LATAM Airlines Logo
6:00 pm - 7:35 am
CNF
-
BOS
14h 35m
1 stop
$666LATAM Airlines
Wed, May 6 - Sun, May 17
Delta Logo
9:05 am - 2:30 pm
BOS
-
CNF
28h 25m
2 stops
Delta Logo
7:10 am - 11:31 pm
CNF
-
BOS
17h 21m
2 stops
$705Delta
Booking Insights

KAYAK's insights & trends for Boston to South America flights

Get data-powered insights and trends into flights from Boston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Boston to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Boston found in the last 72 hours was to Bogotá, at $257 round-trip. The most popular route is from Boston (BOS) to Sao Paulo Guarulhos Intl Airport (GRU), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $581.

Can I save money by flying with a layover from Boston to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $585, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Boston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Boston to South America is September, when tickets cost $533 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $851 and $698 respectively.

How far in advance should I book a flight from Boston to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Boston to South America, you should book around 4 weeks before departure, which saves you about 10% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$104
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 35% increase in price.
Flight from Boston to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Boston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Boston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Boston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Boston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Boston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Boston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Boston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Boston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Boston to South America

 
Need help choosing which airline to fly with from Boston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8357 reviews
8.5Crew
7.8Entertainment
8.1Boarding
7.9Comfort
7.2Food
Airline reviews

Delta is always a wonderful experience. A clean plane and the crew is really friendly.

10.0 ExcellentCharlean, Mar 2026
LAS - ATL
Read more Delta reviews

Delta is always a wonderful experience. A clean plane and the crew is really friendly.

Too many people are taking up space in the overhead bins with their extra piece of luggage. Since they cannot fit their backpacks or extra luggage piece under the seat in front of them, they store it in the overheads and thus taking up room for other passengers. It wasn’t only one or two persons; more like 12 or 13 passengers.

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

This was the worse experience. They delayed our flight twice and we still had to find another flight to get home sooner which was alos delayed. Also, the flight attendant named Ginny on DL9890 leaving at 4:13pm on 3/23/26 was extremely rude.

I love Delta the flight attendants were personable and the flight arrived 1/2 earlier thanks expected. All a plus. The gate agent was a bit flustered but even with that I still had a good experience. Her supervisor assisted me.

Got to fly my favorite plane, the Boeing 767-400ER, to Milan. The soft blush pink mood lighting during meal service was very beautiful and gorgeous. The service was top-notch, and our flights were on time. I highly recommend Delta.

I am still at the Airport! Delayed Delayed and Delyaed

I took seat 15A in anticipation of window seat, there is no window.

The first class flight attendant was awful to everyone. Very rude; no customer service. She should not be working in first class.

Snacks and included beverages were appreciated. Boarding went smoothly. Plenty of overhead bin space. Seats get very uncomfortable after a couple of hours. After waiting 10 painful minutes for my walker, a very nice Delta guest agent pushed me in a wheelchair to the gate. It was finally delivered to me after another 15 minutes . Our checked bag was on the carousel long b4 I was able to retrieve it. Fortunately it was still there but somewhere along the way the straps we used to secure it were removed and and were not reattached. Wish I had made note of the agents name.

Do not book it’s a scam! They stole $1200 from me

Copa staff at PTY and one particular crew member were unhelpful & rude.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight changed gates multiple times and flight had to be delayed multiple times

We called Kayak for a change due to the TSA situation in Atlanta. What we got was a canceled return flight (in error) and we had to find the mistake. Not happy with Kayak who blamed it on AA.

Tv screens and movie selection v good. Friendly staff. They were really worried about max capacity and room for carryons. That is never fun but i had no problem finding space when I boarded.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

Delayed for mechanical and no updates on what was happening and how long the delay might be.

My flight from LGA was cancelled and my rebooked flight from JFK was delayed numerous times. I will now be getting home after 2am.

Flight was delayed half hour before boarding, but when I checked flight aware the plane that would Pick us up had a delay of more than an hour. AA should let us know in advance to avoid waiting several hours in the airport

On the return flight, arriving in Denver we sat on the tarmac in Denver for over 20 minutes.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The flight attendant in business class was excellent! Professional, friendly and attentive.

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Everything you need to know for your flight to South America

Information on your arrival and departure airports