$154 Find Cheap Flights from Boston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Boston to South America departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Flight Deals

Cheap Flights from Boston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$529
Bogotá
Bogotá2 stops$338
Medellín
Medellín2 stops$379
Buenos Aires
Buenos Aires3 stops$780
Sao Paulo
Sao Paulo1 stop$520
Rio de Janeiro
Rio de Janeiro2 stops$597
Santiago
Santiago1 stop$544
Cartagena
Cartagena1 stop$258
Quito
Quito2 stops$298
Guayaquil
Guayaquil3 stops$486
Cali
Cali1 stop$299
Cusco
Cusco2 stops$605
Pereira
Pereira2 stops$426
Georgetown
Georgetown1 stop$399
Montevideo
Montevideo2 stops$698
Barranquilla
Barranquilla1 stop$374
Santa Marta
Santa Marta2 stops$465
Florianopolis
Florianopolis3 stops$606
Lima
Lima2 stops$529
Bogotá
Bogotá2 stops$338
Medellín
Medellín2 stops$379
Buenos Aires
Buenos Aires3 stops$780
Sao Paulo
Sao Paulo1 stop$520
Rio de Janeiro
Rio de Janeiro2 stops$597
Santiago
Santiago1 stop$544
Cartagena
Cartagena1 stop$258
Quito
Quito2 stops$298
Guayaquil
Guayaquil3 stops$486
Cali
Cali1 stop$299
Cusco
Cusco2 stops$605
Pereira
Pereira2 stops$426
Georgetown
Georgetown1 stop$399
Montevideo
Montevideo2 stops$698
Barranquilla
Barranquilla1 stop$374
Santa Marta
Santa Marta2 stops$465
Florianopolis
Florianopolis3 stops$606

Book Cheap Boston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Boston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Boston to South America

Sat, Dec 6 - Thu, Dec 11
Spirit Airlines Logo
10:56 am - 1:12 amBOS-BOG
14h 16m2 stops
Spirit Airlines Logo
2:17 am - 7:06 pmBOG-BOS
16h 49m2 stops
$338Spirit Airlines
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Sun, Dec 7 - Thu, Dec 11
Spirit Airlines Logo
5:45 am - 1:12 amBOS-BOG
19h 27m1 stop
Spirit Airlines Logo
1:47 pm - 10:03 amBOG-BOS
20h 16m1 stop
$342Spirit Airlines
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Thu, Jan 8 - Fri, Jan 23
Copa Airlines Logo
3:07 pm - 5:45 amBOS-BOG
14h 38m1 stop
Copa Airlines Logo
12:08 pm - 10:03 pmBOG-BOS
9h 55m1 stop
$346Copa Airlines
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Wed, Dec 3 - Tue, Dec 9
American Airlines Logo
8:00 am - 9:10 pmBOS-MDE
13h 10m2 stops
American Airlines Logo
1:30 am - 2:12 pmMDE-BOS
12h 42m2 stops
$380American Airlines
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Mon, Mar 30 - Thu, Apr 9
LATAM Airlines Logo
3:05 pm - 5:40 amBOS-GRU
13h 35m1 stop
LATAM Airlines Logo
10:45 pm - 7:35 amGRU-BOS
9h 50mnonstop
$520LATAM Airlines
Find Deal
Tue, Apr 7 - Tue, Apr 28
LATAM Airlines Logo
1:55 pm - 5:40 amBOS-GRU
14h 45m1 stop
LATAM Airlines Logo
10:35 am - 11:25 pmGRU-BOS
13h 50m1 stop
$525LATAM Airlines
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Mon, Dec 8 - Mon, May 4
Delta Logo
8:55 am - 8:55 pmBOS-GRU
10h 00mnonstop
Delta Logo
8:30 pm - 11:23 amGRU-BOS
15h 53m1 stop
$526Delta
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Sun, Dec 7 - Mon, May 4
Delta Logo
6:45 am - 5:40 amBOS-GRU
20h 55m1 stop
Delta Logo
8:30 pm - 11:23 amGRU-BOS
15h 53m1 stop
$530Delta
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Sun, Jan 25 - Mon, Feb 2
Copa Airlines Logo
3:07 pm - 1:20 amBOS-LIM
10h 13m1 stop
Copa Airlines Logo
3:30 am - 10:03 pmLIM-BOS
18h 33m1 stop
$531Copa Airlines
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Wed, Mar 11 - Mon, Mar 23
American Airlines Logo
2:12 pm - 10:05 amBOS-GIG
18h 53m2 stops
American Airlines Logo
11:00 pm - 1:40 pmGIG-BOS
15h 40m1 stop
$599American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Boston to South America flights

Get data-powered insights and trends into flights from Boston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Boston to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Boston found in the last 72 hours was to Bogotá, at $345 round-trip. The most popular route is from Boston (BOS) to Sao Paulo Guarulhos Intl Airport (GRU), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $361.

Can I save money by flying with a layover from Boston to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $472, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Boston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Boston to South America is September, when tickets cost $522 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $876 and $712 respectively.

What’s the cheapest day of the week to fly from Boston to South America?

The average price of all round-trip flights from Boston to South America clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Boston to South America, look for departures on Mondays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from South America, Tuesday is the cheapest day to fly and Saturday is the most expensive.

How far in advance should I book a flight from Boston to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Boston to South America, you should book around 2 weeks before departure, which saves you about 9% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$154
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 33% increase in price.
Flight from Boston to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Boston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Boston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Boston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Boston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Boston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Boston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Boston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Boston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $508 on average. Morning departures are around 4% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $594.

Reviews of the top 5 airlines serving from Boston to South America

 
Need help choosing which airline to fly with from Boston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8003 reviews
8.1Boarding
7.9Entertainment
7.3Food
8.5Crew
7.9Comfort
Airline reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

8.0 ExcellentAnonymous, Nov 2025SFO - MSP
Read more Delta reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

Great experience with a crew always thinking in the passenger

Very happy with my flight. I would definitely recommend it.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Horrible the worst airlines I have ever flown. Cancelled flight with no choices and when contacted them they were not helpful

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

We were very rushed by a staff member at the gate when transferring from American Airlines to Fijian. Then the plane stayed put for ages anyhow! The plane was delayed and my bag sent to San Francisco instead of Fiji

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Boarding, crew were excellent, food was ok and entertainment need to improve

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Everything you need to know for your flight to South America

Information on your arrival and departure airports