$133 Find Cheap Flights from Boston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Boston to South America departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Boston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$490
Bogotá
Bogotá1 stop$362
Medellín
Medellín2 stops$414
Buenos Aires
Buenos Aires1 stop$761
Sao Paulo
Sao Paulo1 stop$596
Rio de Janeiro
Rio de Janeiro1 stop$662
Santiago
Santiago1 stop$652
Cartagena
Cartagena2 stops$314
Quito
Quito1 stop$422
Guayaquil
Guayaquil1 stop$392
Cali
Cali1 stop$426
Cusco
Cusco2 stops$694
Georgetown
Georgetown1 stop$542
Pereira
Pereira1 stop$523
Barranquilla
Barranquilla1 stop$404
Montevideo
Montevideo2 stops$830
Santa Marta
Santa Marta1 stop$379
Asuncion
Asuncion1 stop$846
Lima
Lima1 stop$490
Bogotá
Bogotá1 stop$362
Medellín
Medellín2 stops$414
Buenos Aires
Buenos Aires1 stop$761
Sao Paulo
Sao Paulo1 stop$596
Rio de Janeiro
Rio de Janeiro1 stop$662
Santiago
Santiago1 stop$652
Cartagena
Cartagena2 stops$314
Quito
Quito1 stop$422
Guayaquil
Guayaquil1 stop$392
Cali
Cali1 stop$426
Cusco
Cusco2 stops$694
Georgetown
Georgetown1 stop$542
Pereira
Pereira1 stop$523
Barranquilla
Barranquilla1 stop$404
Montevideo
Montevideo2 stops$830
Santa Marta
Santa Marta1 stop$379
Asuncion
Asuncion1 stop$846

Book Cheap Boston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Boston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Boston to South America

Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
8:00 pm - 12:35 pm
BOS
-
CTG
17h 35m
2 stops
American Airlines Logo
1:35 pm - 8:41 am
CTG
-
BOS
18h 06m
2 stops
$314American Airlines
Fri, Jun 12 - Tue, Jun 16
American Airlines Logo
6:00 pm - 2:13 pm
BOS
-
CTG
21h 13m
1 stop
American Airlines Logo
1:35 pm - 8:41 am
CTG
-
BOS
18h 06m
2 stops
$322American Airlines
Thu, Sep 17 - Mon, Sep 21
Copa Airlines Logo
3:55 pm - 8:40 am
BOS
-
CTG
17h 45m
1 stop
Copa Airlines Logo
9:45 am - 11:02 pm
CTG
-
BOS
12h 17m
1 stop
$355Copa Airlines
Wed, Oct 7 - Tue, Oct 13
LATAM Airlines Logo
7:00 am - 5:50 pm
BOS
-
BOG
11h 50m
1 stop
LATAM Airlines Logo
11:00 am - 11:23 pm
BOG
-
BOS
11h 23m
1 stop
$362LATAM Airlines
Wed, Oct 14 - Sun, Oct 25
Avianca Logo
4:50 pm - 2:00 am
BOS
-
BOG
10h 10m
1 stop
Avianca Logo
4:00 am - 2:50 pm
BOG
-
BOS
9h 50m
1 stop
$364Avianca
Thu, Aug 13 - Wed, Aug 19
LATAM Airlines Logo
3:20 pm - 5:50 pm
BOS
-
BOG
27h 30m
1 stop
LATAM Airlines Logo
10:35 am - 11:20 pm
BOG
-
BOS
11h 45m
1 stop
$365LATAM Airlines
Wed, Sep 23 - Thu, Oct 29
Copa Airlines Logo
3:55 pm - 10:10 am
BOS
-
BOG
19h 15m
1 stop
Copa Airlines Logo
7:00 am - 11:03 pm
BOG
-
BOS
15h 03m
1 stop
$373Copa Airlines
Sat, Jun 20 - Tue, Jul 21
Delta Logo
7:05 am - 8:35 pm
BOS
-
BOG
14h 30m
1 stop
Delta Logo
2:55 pm - 1:20 am
BOG
-
BOS
9h 25m
1 stop
$376Delta
Sat, Jun 13 - Sat, Jun 13
Avianca Logo
8:45 am - 6:05 pm
BOS
-
MDE
10h 20m
1 stop
Avianca Logo
10:45 pm - 2:50 pm
MDE
-
BOS
15h 05m
2 stops
$425Avianca
Sun, Sep 6 - Thu, Sep 24
Delta Logo
6:45 am - 6:59 pm
BOS
-
UIO
13h 14m
1 stop
Delta Logo
7:55 am - 1:17 am
UIO
-
BOS
16h 22m
2 stops
$434Delta
Booking Insights

KAYAK's insights & trends for Boston to South America flights

Get data-powered insights and trends into flights from Boston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Boston to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Boston found in the last 7 days was to Bogotá, at $400 round-trip. The most popular route is from Boston (BOS) to Sao Paulo Guarulhos Intl Airport (GRU), and the cheapest round-trip airline ticket found on this route in the last 7 days was $544.

Can I save money by flying with a layover from Boston to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $585, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Boston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Boston to South America is January, when tickets cost $588 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $982 and $826 respectively.

How far in advance should I book a flight from Boston to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Boston to South America, you should book around 2 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$133
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 34% increase in price.
Flight from Boston to Medellín Jose Maria Cordova Intl

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Boston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Boston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Boston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Boston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Boston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Boston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Boston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Boston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Boston to South America

 
Need help choosing which airline to fly with from Boston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8423 reviews
8.1Boarding
7.2Food
7.8Comfort
8.5Crew
7.8Entertainment
Airline reviews

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

6.0 GoodAnonymous, May 2026
ATL - ECP
Read more Delta reviews

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

The crew were efficient. The pilots seemed professional. It was a bit chilly in our seats. The sheet provided weren’t very helpful.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

The Boarding process was great. Particularly since my wife and I require assistance. The flight attendants were amazing. We travel frequently; they honestly were a cut above. 😀

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Do not book it’s a scam! They stole $1200 from me

Copa staff at PTY and one particular crew member were unhelpful & rude.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Awful, tons of delays, I got into Chicago multiple hours late meaning I hit the very traffic I tried so desperately to avoid. Just empty apologies from American Airlines text alerts. Trash behavior from a trash airline.

The flight attendants were very friendly, efficient, and helpful. The plane was ahead of schedule, and it all went very smoothly. Thank you.

They lost my baggage and I am still struggling to the information and update

We got delayed getting out of DFW for broken overhead bins. Once the flight got underway the captain kept the seatbelt sign lit the entire flight despite little perceptible turbulence, preventing use of the rest rooms and any sort of refreshment service in the main cabin.

Flight delays for communication overall not a good experience uncomfortable on the plane. Person in front of me reclined his seat, putting them inches from my lap.

There were flight delays making our flight arrive at our destination after midnight didn’t seem to have enough crew or airplanes for the flights laid over in Dallas should’ve had plenty of time to make it to our next flight only made it because that flight was also delayed because our plane wasn’t even at the airport yet overall have not had a good experience on American

Flight left on time. Captain provided relevant announcements. We had to wait 45 minutes to desembark due to the ramp closed because of lightening.

It's a long flight and that is always difficult. I was comfortable and well. The movies available were great and the crew was good.

A flawless trip, great experience. Keep up the good work!

Overall, the flight went well and the service was good. However, there was a very frightening moment during landing in Bogotá. Just as the plane was about to touch down, it suddenly went back up into the air. The aircraft was not descending straight and seemed to move left and right, which made the situation feel unstable. This was quite scary. After going back up, the plane circled for about 15 minutes before attempting to land again. Although I understand that safety always comes first and situations like this can happen, it was still a shocking experience for passengers.

They should provide water to passengers who ask for it

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Everything you need to know for your flight to South America

Information on your arrival and departure airports