$124 Find Cheap Flights from Boston to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Boston to South America departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Boston to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$379
Bogotá
Bogotá1 stop$347
Medellín
Medellín1 stop$287
Buenos Aires
Buenos Aires2 stops$722
Sao Paulo
Sao Paulononstop$458
Rio de Janeiro
Rio de Janeiro2 stops$544
Santiago
Santiago3 stops$561
Cartagena
Cartagena1 stop$233
Quito
Quito1 stop$365
Guayaquil
Guayaquil1 stop$261
Cali
Cali1 stop$226
Cusco
Cusco2 stops$655
Georgetown
Georgetown1 stop$475
Pereira
Pereira1 stop$417
Montevideo
Montevideo2 stops$776
Barranquilla
Barranquilla1 stop$333
Santa Marta
Santa Marta2 stops$468
Asuncion
Asuncion2 stops$704
Lima
Lima1 stop$379
Bogotá
Bogotá1 stop$347
Medellín
Medellín1 stop$287
Buenos Aires
Buenos Aires2 stops$722
Sao Paulo
Sao Paulononstop$458
Rio de Janeiro
Rio de Janeiro2 stops$544
Santiago
Santiago3 stops$561
Cartagena
Cartagena1 stop$233
Quito
Quito1 stop$365
Guayaquil
Guayaquil1 stop$261
Cali
Cali1 stop$226
Cusco
Cusco2 stops$655
Georgetown
Georgetown1 stop$475
Pereira
Pereira1 stop$417
Montevideo
Montevideo2 stops$776
Barranquilla
Barranquilla1 stop$333
Santa Marta
Santa Marta2 stops$468
Asuncion
Asuncion2 stops$704

Book Cheap Boston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Boston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Boston to South America

Tue, Feb 3 - Wed, Feb 18
Spirit Airlines Logo
5:34 am - 2:15 pm
BOS
-
MDE
8h 41m
1 stop
Spirit Airlines Logo
3:15 pm - 11:44 pm
MDE
-
BOS
8h 29m
1 stop
$287Spirit Airlines
Wed, Jan 28 - Thu, Feb 5
Spirit Airlines Logo
5:34 am - 2:15 pm
BOS
-
MDE
8h 41m
1 stop
Spirit Airlines Logo
3:15 pm - 11:57 pm
MDE
-
BOS
8h 42m
1 stop
$289Spirit Airlines
Thu, Feb 5 - Mon, Feb 9
Avianca Logo
7:55 am - 5:05 pm
BOS
-
MDE
9h 10m
1 stop
Avianca Logo
4:15 pm - 6:35 am
MDE
-
BOS
14h 20m
1 stop
$301Avianca
Mon, Mar 2 - Fri, Mar 6
Avianca Logo
3:25 pm - 12:55 pm
BOS
-
MDE
21h 30m
1 stop
Avianca Logo
6:45 pm - 6:35 am
MDE
-
BOS
11h 50m
1 stop
$310Avianca
Fri, Jan 30 - Sun, Feb 1
Copa Airlines Logo
7:31 am - 12:05 am
BOS
-
BOG
16h 34m
1 stop
Copa Airlines Logo
4:45 am - 1:39 pm
BOG
-
BOS
8h 54m
1 stop
$348Copa Airlines
Sun, Mar 1 - Sun, Mar 15
LATAM Airlines Logo
7:59 pm - 8:40 am
BOS
-
BOG
12h 41m
2 stops
LATAM Airlines Logo
3:55 pm - 3:09 pm
BOG
-
BOS
22h 14m
2 stops
$358LATAM Airlines
Wed, Apr 8 - Thu, Apr 23
LATAM Airlines Logo
9:55 am - 8:40 pm
BOS
-
GRU
9h 45mnonstop
LATAM Airlines Logo
10:45 pm - 7:35 am
GRU
-
BOS
9h 50mnonstop
$458LATAM Airlines
Mon, Feb 2 - Thu, Feb 5
Copa Airlines Logo
3:07 pm - 12:15 am
BOS
-
GRU
31h 08m
1 stop
Copa Airlines Logo
5:25 am - 10:03 pm
GRU
-
BOS
18h 38m
1 stop
$459Copa Airlines
Wed, Feb 25 - Thu, Mar 26
American Airlines Logo
3:49 pm - 4:50 pm
BOS
-
CNF
23h 01m
2 stops
American Airlines Logo
6:10 pm - 11:44 am
CNF
-
BOS
18h 34m
2 stops
$644American Airlines
Mon, Apr 13 - Mon, May 4
American Airlines Logo
4:35 pm - 11:55 am
BOS
-
CNF
18h 20m
2 stops
American Airlines Logo
3:25 pm - 10:02 am
CNF
-
BOS
19h 37m
2 stops
$645American Airlines
Booking Insights

KAYAK's insights & trends for Boston to South America flights

Get data-powered insights and trends into flights from Boston to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Boston to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Boston found in the last 72 hours was to Bogotá, at $262 round-trip. The most popular route is from Boston (BOS) to Sao Paulo Guarulhos Intl Airport (GRU), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $437.

Can I save money by flying with a layover from Boston to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $684, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Boston to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Boston to South America is September, when tickets cost $528 (return) on average. On the other hand, the most expensive months are December and July, when the average cost of round-trip tickets is $849 and $708 respectively.

How far in advance should I book a flight from Boston to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Boston to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Boston to South America, you should book around 2 weeks before departure, which saves you about 7% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 17 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$124
Best time to beat the crowds with an average 17% drop in price.
Most popular time to fly with an average 32% increase in price.
Flight from Boston to Medellín Jose Maria Cordova Intl

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Boston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Boston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Boston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Boston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Boston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Boston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Boston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Boston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Boston to South America

 
Need help choosing which airline to fly with from Boston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8079 reviews
7.2Food
7.9Comfort
8.5Crew
8.1Boarding
7.8Entertainment
Airline reviews

I upgraded to first. Quick and easy boarding. Comfortable seat with power and a nice IPA.

10.0 ExcellentJay, Jan 2026
ATL - BDL
Read more Delta reviews

I upgraded to first. Quick and easy boarding. Comfortable seat with power and a nice IPA.

Probably not the fault of Delta but there was delay after delay after delay and I ended up getting home 4 hours later then I should have at 1:30 in the morning

Easiest airport experience ever in my life at MSP with Delta check-in and flight attendant gave us a bottle of champagne in celebration of our 10-year wedding anniversary, so overall amazing!

No in flight service, no explanation - FC got service, C+ did not, unsure about Economy. No turbulence to speak of, so I guess another way to cut cost, or promote health and well being of Delta employees? Also, boarding in MEM combined zones, and with overhead space already full on both flights after Zone 2/ Diamond, presents a huge challenge to find a space for a bag. Delta, other than point A to B, is no longer reasonable to fly - very poor experiences, not even taking into account the chastising at the gate and rude crews, across the board.

It would have been better if the flight wasn't delayed by 2.5 hours

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

Delta flight Delay for ,more that two hours i.e original flight was 6.30 PM and it starts at 8.45 PM, When we connect Delta team for meal vouchers as it is late arrival in designation,But we did not get it as per delta policy , which is not good for mid night arrival,

Inexperienced boarding crew allowed too many bags on to a full flight and delayed takeoff causing a missed connection and unplanned overnight stay. There was a hotel at the airport but Delta would not pay for it offering only to shuttle me to an area hotel. Never even offerred so much as an apology by anyone working for Delta.

Staff was great! Kind and cordial! Middle seat row 28 seat B has a hump in it. Trays were getting stuck when putting down and up. Good flight

Departure was delayed resulting in me missing my connection. Delta did not autimatically find me another flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

They made me pay $40 to check a bag that was listed as free when I bought my ticket. Then before boarding they offered to check any bags free.

It was a good trip. Flight Attendants were friendly and responsive.

Qatar airways ,boarding arrangements at Hamid international airport could been better

Crew in Columbia was not prepared for landing. It was a bit of a disaster and getting bags took forever.

My seat tv didn’t work the whole trip. And the seat space is too small despite being seated at the front.

The seat cushions were very worn so they were extremely uncomfortable.

Delayed, no updates, had a rewards number but was not working

The seats from lax to DFW was so tight that I could not move my legs . No WiFi and had to pay . Not a good selection of entertainment

AA should improve their in air internet & entertainment options. Seems unreasonable to charge $20/hr and should have some form of free connections. The entertainment options are also pretty limited, movies are outdated and the series only show 3-5 episodes.

The professionals have excellent customer service, the seats don´t have enough space.

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Everything you need to know for your flight to South America

Information on your arrival and departure airports