SFO

$180 Find Cheap Flights from Cape Cod and the Islands to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Francisco departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Cape Cod and the Islands to San Francisco

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Cape Cod and the Islands to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Cape Cod and the Islands to San Francisco

Fri, Sep 4 - Fri, Sep 4
American Airlines Logo
10:41 am - 6:56 pmMVY  West Tisbury Martha's Vineyard-SFO San Francisco
11h 15m1 stop Philadelphia
American Airlines Logo
11:40 pm - 12:40 pmSFO  San Francisco-MVY West Tisbury Martha's Vineyard
10h 00m1 stop Charlotte Douglas
$445American Airlines
Wed, Aug 26 - Sun, Aug 30
American Airlines Logo
12:42 pm - 6:56 pmHYA  Hyannis Barnstable-SFO San Francisco
9h 14m1 stop Philadelphia
American Airlines Logo
10:12 pm - 12:12 pmSFO  San Francisco-HYA Hyannis Barnstable
11h 00m1 stop Philadelphia
$579American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
12:42 pm - 9:09 pmHYA  Hyannis Barnstable-SFO San Francisco
11h 27m1 stop Philadelphia
American Airlines Logo
10:12 pm - 12:12 pmSFO  San Francisco-HYA Hyannis Barnstable
11h 00m1 stop Philadelphia
$579American Airlines
Tue, Aug 25 - Sat, Aug 29
American Airlines Logo
12:42 pm - 9:09 pmHYA  Hyannis Barnstable-SFO San Francisco
11h 27m1 stop Philadelphia
American Airlines Logo
10:12 pm - 12:12 pmSFO  San Francisco-HYA Hyannis Barnstable
11h 00m1 stop Philadelphia
$614American Airlines
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
12:42 pm - 6:56 pmHYA  Hyannis Barnstable-SFO San Francisco
9h 14m1 stop Philadelphia
American Airlines Logo
3:46 pm - 12:12 pmSFO  San Francisco-HYA Hyannis Barnstable
17h 26m2 stops Phoenix Sky Harbor Intl Philadelphia
$616American Airlines
Thu, Aug 27 - Mon, Aug 31
American Airlines Logo
3:00 pm - 10:59 pmMVY  West Tisbury Martha's Vineyard-SFO San Francisco
10h 59m1 stop Philadelphia
American Airlines Logo
10:12 pm - 12:00 pmSFO  San Francisco-MVY West Tisbury Martha's Vineyard
10h 48m1 stop Philadelphia
$626American Airlines
Thu, Aug 27 - Mon, Aug 31
American Airlines Logo
12:42 pm - 8:07 pmHYA  Hyannis Barnstable-SFO San Francisco
10h 25m1 stop Philadelphia
American Airlines Logo
10:12 pm - 12:12 pmSFO  San Francisco-HYA Hyannis Barnstable
11h 00m1 stop Philadelphia
$633American Airlines
Tue, Aug 25 - Sat, Aug 29
American Airlines Logo
1:47 pm - 11:45 pmHYA  Hyannis Barnstable-SFO San Francisco
12h 58m2 stops New York LaGuardia Chicago O'Hare Intl
American Airlines Logo
10:12 pm - 12:12 pmSFO  San Francisco-HYA Hyannis Barnstable
11h 00m1 stop Philadelphia
$644American Airlines
Fri, Sep 11 - Sat, Sep 19
Multiple Airlines Logo
11:13 am - 11:31 pmEWB  New Bedford Regional-SFO San Francisco
15h 18m2 stops West Tisbury Martha's Vineyard New York John F Kennedy Intl
Multiple Airlines Logo
10:10 pm - 3:45 pmSFO  San Francisco-EWB New Bedford Regional
14h 35m2 stops Boston Logan Intl Nantucket Memorial
$650Multiple Airlines
Thu, Aug 27 - Mon, Aug 31
American Airlines Logo
10:41 am - 7:13 pmMVY  West Tisbury Martha's Vineyard-SFO San Francisco
11h 32m2 stops Philadelphia Dallas/Fort Worth
American Airlines Logo
10:12 pm - 12:00 pmSFO  San Francisco-MVY West Tisbury Martha's Vineyard
10h 48m1 stop Philadelphia
$658American Airlines
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Good to know

Low season

January
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 15% lower on average.

FAQs for booking flights from Cape Cod and the Islands to San Francisco

  • How does KAYAK find such low prices on flights from Cape Cod and the Islands to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Cape Cod and the Islands to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Cape Cod and the Islands to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Cape Cod and the Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Cape Cod and the Islands to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Cape Cod and the Islands with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Cape Cod and the Islands to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Cape Cod and the Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Cape Cod and the Islands to San Francisco

 
Need help choosing which airline to fly with from Cape Cod and the Islands to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
JetBlueOverall score based on 3037 reviews
7.3Boarding
7.2Entertainment
7.9Crew
6.6Food
7.5Comfort
Airline reviews

Everything was good except checking bags . I had paid for two bags but it didn’t show so we had to do it again while people waited and we were struggling to get to our flight

8.0 ExcellentEric, Jul 2026
Read more JetBlue reviews

Everything was good except checking bags . I had paid for two bags but it didn’t show so we had to do it again while people waited and we were struggling to get to our flight

Flight delayed 4 times on a non-stop from BOS to SFO. Then when landed in SFO had to wait for 30 mins for a gate AT 3:30AM.

The security line at JFK was one of the longest I’ve ever experienced - probably 45 minutes. I don’t know if JetBlue has control over it, but it detracted from the overall experience. Entertainment had good options, but the volume control was a bit small to tap on and the screen had a fair amount of interference blips. Clearer picture would have been better.

Whole experience was poor. Delayed 2 hours. Lied about the delays. Was all jet blues fault and tried to blame on air traffic control. Sent out other let trips and wouldn't allow people to switch aircraft.

Kayak sucked. You gave me a confirmation number that was not useable by the jet blue system. Nor did you send any check in emails. I’ll not be using your site again. Nice work.

Flight emergency landed in Chicago due to “Odor” in back of plane . Had to buy ANOTHER TICKET to get to Boston cash out of my own pocket . Then they would notchange my return flight time without a 400. Charge!!!! Insulting.

we were an hour delayed after boarding and given no reason. Headsets cost money. Also there were openrows with no one setting in them but we were told we were not allowed to swtich.

Very pleasant flight attendants. Gate crew rather loud chatting with each other.

Communication with the customer and stay is important. Staff off with a minor inconvenience but it worked out of course. Also this was a very old Mint Class plane. They snuck this one in on us. The updated aircraft are much better.

Service for food to our seat was a bit slow. Snack choices were just pretzels or baked chips. My seat cushion was not attached. Other than Barbie, video choice were not very good or current.

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Everything you need to know for your flight to San Francisco

Information on the airport you'll fly into in San Francisco

San Francisco (SFO)