$435 Find Cheap Flights from Central America to Santa Fe

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Santa Fe departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$659
American Airlines
Sat 2/21Fri 2/27
GUA - SAF • 1 stop
Cheapest one-way
$435
American Airlines
Fri 1/23
GUA - SAF • 1 stop
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Flight Deals
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Flight Deals

Cheap Flights from Central America to Santa Fe

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Central America to Santa Fe that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Central America to Santa Fe

Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
6:37 am - 9:09 pm
GUA
-
SAF
15h 32m1 stop
American Airlines Logo
6:15 am - 12:12 am
SAF
-
GUA
16h 57m1 stop
$659American Airlines
Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
3:06 pm - 3:05 pm
GUA
-
SAF
24h 59m2 stops
American Airlines Logo
4:15 pm - 12:12 am
SAF
-
GUA
6h 57m1 stop
$664American Airlines
Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
4:13 pm - 12:24 pm
GUA
-
SAF
21h 11m2 stops
American Airlines Logo
4:15 pm - 12:51 pm
SAF
-
GUA
19h 36m2 stops
$688American Airlines
Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
6:37 am - 9:09 pm
GUA
-
SAF
15h 32m1 stop
American Airlines Logo
6:15 am - 12:12 am
SAF
-
GUA
16h 57m1 stop
$693American Airlines
Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
4:13 pm - 12:24 pm
GUA
-
SAF
21h 11m2 stops
American Airlines Logo
4:15 pm - 12:12 am
SAF
-
GUA
6h 57m1 stop
$698American Airlines
Sat, Feb 21 - Fri, Feb 27
American Airlines Logo
3:06 pm - 3:05 pm
GUA
-
SAF
24h 59m2 stops
American Airlines Logo
4:15 pm - 12:51 pm
SAF
-
GUA
19h 36m2 stops
$722American Airlines
Fri, May 1 - Tue, May 5
United Airlines Logo
12:35 pm - 9:34 am
SAP
-
SAF
20h 59m2 stops
United Airlines Logo
5:49 pm - 11:32 am
SAF
-
SAP
17h 43m2 stops
$5,674United Airlines
Fri, May 1 - Tue, May 5
United Airlines Logo
6:15 am - 9:13 pm
SAP
-
SAF
14h 58m2 stops
United Airlines Logo
1:19 pm - 11:32 am
SAF
-
SAP
22h 13m3 stops
$6,185United Airlines
Useful Info

FAQs for booking flights from Central America to Santa Fe

  • How does KAYAK find such low prices on flights from Central America to Santa Fe?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Central America to Santa Fe.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Central America to Santa Fe?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Fe from Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Central America to Santa Fe?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Fe with an airline and back to Central America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Central America to Santa Fe?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Fe from Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Central America to Santa Fe

 
Need help choosing which airline to fly with from Central America to Santa Fe? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11103 reviews
6.9Entertainment
7.5Boarding
7.2Comfort
8.0Crew
6.4Food
Airline reviews

Lower WiFi prices; allow us to see our flight on a map; more variety of drink choices.

6.0 GoodJonathan, Jan 2026
CLT - DFW
Read more American Airlines reviews

Lower WiFi prices; allow us to see our flight on a map; more variety of drink choices.

I was originally scheduled on AA 1763. When I landed in Miami, I went to the counter for flight AA 2115 to try to move my flight to this one. I was in a first class seat on AA 1763. While they moved to me this flight, I was told that there were no other 1st class seats available and they assigned me into coach. However, when I was getting off the plane I noticed that one of the pilots who was also in line to go jump seat - somehow miraculously got a 1st class seat on this flight. It is actually infuriating that I had a paid 1st class seat yet somehow they would move an AA employee ahead of that. At a bare minimum, they should have compensated me for the fare difference and I really think paying customers should ALWAYs get the premiere seats.

So excited very proud first of all I wanna thank kayak all updates very professional and fast alart And amazing cabin crew so nice to me they deserve big salute

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

We experienced gate changes and a long delay. My seat was dirty when I boarded and I had to use wipes to clean it myself. There was an unpleasant and overpowering cleaning product scent on the plane as well that lingered through the flight.

Seats were much more cramped then on the 737. Narrower and rows closer together. Flight was absolutely packed and the plugs under the seats didn't work. Was forced to check my bag even though previous flight had no issue with it.

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

The flight was on time and arrived early. The crew were friendly and helpful.

We had a 2 hour delay that impacted our comanions further travel. I have a feeling AA knows there is a problem at the Cabo airport and does not account for that.

Everything you need to know for your flight to Santa Fe

Information on the airport you'll fly into in Santa Fe