$374 Find Cheap Flights from Charleston to Panama

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Panama departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flights Deals
Booking Insights
Flights Deals

Cheap Flights from Charleston to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City2 stops$374
Panama City
Panama City2 stops$374

Book Cheap Charleston to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Panama

Mon, Jan 12 - Fri, Jan 23
American Airlines Logo
7:46 pm - 1:10 pmCHS-PTY
17h 24m2 stops
American Airlines Logo
2:45 pm - 10:21 amPTY-CHS
19h 36m2 stops
$374American Airlines
Find Deal
Mon, Nov 17 - Thu, Nov 27
Delta Logo
6:30 am - 1:52 pmCHS-PTY
7h 22m1 stop
Delta Logo
3:17 pm - 11:24 amPTY-CHS
20h 07m1 stop
$376Delta
Find Deal
Thu, Sep 4 - Tue, Sep 16
American Airlines Logo
5:36 pm - 2:31 pmCHS-PTY
21h 55m2 stops
American Airlines Logo
1:45 pm - 10:08 amPTY-CHS
19h 23m2 stops
$381American Airlines
Find Deal
Fri, Sep 19 - Mon, Sep 29
Delta Logo
5:10 am - 12:55 pmCHS-PTY
8h 45m1 stop
Delta Logo
2:10 pm - 10:33 pmPTY-CHS
7h 23m1 stop
$389Delta
Find Deal
Sun, Aug 31 - Thu, Sep 4
American Airlines Logo
4:22 pm - 2:30 pmCHS-PTY
23h 08m2 stops
American Airlines Logo
3:31 pm - 11:37 pmPTY-CHS
7h 06m1 stop
$394American Airlines
Find Deal
Sun, Aug 31 - Thu, Sep 4
American Airlines Logo
7:50 pm - 2:30 pmCHS-PTY
19h 40m1 stop
American Airlines Logo
3:31 pm - 11:37 pmPTY-CHS
7h 06m1 stop
$398American Airlines
Find Deal
Thu, Sep 4 - Mon, Sep 8
United Airlines Logo
5:16 pm - 2:14 pmCHS-PTY
21h 58m1 stop
United Airlines Logo
3:30 pm - 4:35 pmPTY-CHS
24h 05m1 stop
$406United Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
7:08 am - 2:31 pmCHS-PTY
8h 23m1 stop
American Airlines Logo
3:31 pm - 11:37 pmPTY-CHS
7h 06m1 stop
$409American Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
7:28 pm - 2:31 pmCHS-PTY
20h 03m2 stops
American Airlines Logo
3:31 pm - 11:37 pmPTY-CHS
7h 06m1 stop
$414American Airlines
Find Deal
Thu, Sep 4 - Tue, Sep 16
United Airlines Logo
5:16 pm - 2:14 pmCHS-PTY
21h 58m1 stop
United Airlines Logo
3:30 pm - 10:07 pmPTY-CHS
29h 37m1 stop
$495United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Charleston to Panama flights

Get data-powered insights and trends into flights from Charleston to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charleston to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charleston to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charleston to Panama is November, when tickets cost $402 (return) on average. On the other hand, the most expensive months are March and April, when the average cost of round-trip tickets is $682 and $659 respectively.

What’s the cheapest day of the week to fly from Charleston to Panama?

The average price of all round-trip flights from Charleston to Panama clicked on KAYAK for each day over the last 12 months.

For Charleston to Panama, Wednesday is the cheapest day to fly on average and Sunday is the most expensive. Flying from Panama back to Charleston, the best deals are generally found on Wednesday, with Sunday being the most expensive.


Good to know

Low seasonMay
Cheapest flight$374
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 12% increase in price.
Flight from Charleston to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Charleston to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $466 on average. On average, there is no price difference when choosing to fly in the morning or the evening on this flight route. The most expensive time of day to fly to Panama is generally in the evening, which is peak travel time and where the average cost of a ticket is $495.

Reviews of the top 3 airlines serving from Charleston to Panama

 
Need help choosing which airline to fly with from Charleston to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7980 reviews
8.5Crew
7.9Comfort
7.9Entertainment
7.3Food
8.2Boarding
Airline reviews

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

2.0 MediocreGim, Jul 2025BGM - DTW
Read more Delta reviews

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

Delayed and took off even later than the scheduled delay time

For a 69 year old with health problems I had the worse experience, no wheelchair when I entered a lady told me to sit and wait while a gentleman told me I had to walk to the Delta station, which I did. I had a carry on and a bag, and I was traveling with my service dog, which was on his carrier and the lady charged me for my carry on luggage, beside all the waiting cause of the delay, I had to walk to get my luggage cause no wheelchair showed up, I am so disappointed. I will get in touch with the company. I got home at 3:00 am, not good for my health situation.

Only issue was with seating. The economy fare we purchased did say there was no guarantee the three people in our party would be seated together, and we were not. At the gate, the agent told us more specifically, the fare we purchased meant we would be seated in middle seats only. This should just be made more obvious.

Great experience on Delta. Staff from baggage check to flight attendants were very courteous and professional. My only issue was a personal preference for pretzels instead of the chips and cookies that were offered.

There was no problems, just a little uncomfortable with seats that do not lay back a little

Always good but we must do something about people in rows ahead of you that don't put their seats back up when they are suppose to. And It's rough to not be able to even lean over to get something out of my purse.

Flight was delayed, 30+ bags had to be gate checked. Crew were very friendly!

Everything was good until we were boarding our connection flight in Atlanta, we were told to gate check our carry-on, but when we got inside the plane, there was plenty of room in the overhead.

Did not know my son and I had different seating arrangements. He was fine, but it was disappointing.

Terrible. Delayed 7 hours, and cancelled the flight, leaving me stranded and out of pocket $500 for an alternative last minute flight

Was on time until within 1 hour of flight-how does that happen? Staff very friendly.

the delay for 3 hours was understandable due to weather conditions but the flight should’ve provided some on flight compensations or at least provide more food.

Weather delay in Chicago?. No sense of urgency to make connection in Chicago for our connecting flight that wasn't delayed. Connection was missed.

Our flight was understandably diverted to a small regional airport in Laramie, Wyoming due to weather conditions, which I fully recognize and appreciate. However, the low rating stems from the experience that followed: passengers remained on board for over an hour without the option to deplane and stretch, despite the aircraft being stationary. Although the pilot opened the cabin door, only he was permitted to exit. Meanwhile, passengers grew increasingly uncomfortable as warm summer air entered the cabin through the open door, and being in the second row meant we were impacted immediately. While the flight attendants made efforts to keep everyone at ease, I believe allowing passengers to deplane briefly, given the extended delay, would have significantly improved the overall experience.

I never flew. Flight was canceled. DIA worst airport in the country. Avoid at all costs.

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

The best airline I have ever travel , really good customer service, attention and service !!

United could have one single once of customer service. No human United employee would help me with the invalid mileage plus number, they said I had to speak with the computer.

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

The plane was broken so we had to change planes.

Everything you need to know for your flight from Charleston to Panama

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.