CHS - STI

$369 Find Cheap Flights from Charleston to Santiago de los Caballeros

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to Santiago de los Caballeros departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago de los Caballeros

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santiago de los Caballeros, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Charleston to Santiago de los Caballeros, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$379
JetBlue
Thu 5/7Mon 5/11
CHS - STI • 1 stop
Top airlines
Spirit Airlines
Cheapest • from $369 (round-trip)
American Airlines
Best reviews • 7.1 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Charleston and Santiago de los Caballeros. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
New York (JFK)
Cheapest • Avg $526 (round-trip)
Miami (MIA)
Shortest trip • 6h 00m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago de los Caballeros!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charleston to Santiago de los Caballeros (CHS-STI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to Santiago de los Caballeros that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to Santiago de los Caballeros

Thu, May 7 - Mon, May 11
JetBlue Logo
11:00 am - 11:56 pm
CHS
-
STI
12h 56m
1 stop
JetBlue Logo
8:31 am - 7:13 pm
STI
-
CHS
10h 42m
1 stop
$379JetBlue
Sat, May 16 - Mon, May 18
American Airlines Logo
6:20 pm - 12:23 pm
CHS
-
STI
18h 03m
2 stops
American Airlines Logo
1:32 pm - 11:12 am
STI
-
CHS
21h 40m
2 stops
$387American Airlines
Fri, May 15 - Sun, May 17
American Airlines Logo
4:46 pm - 12:23 pm
CHS
-
STI
19h 37m
2 stops
American Airlines Logo
1:32 pm - 8:31 am
STI
-
CHS
18h 59m
2 stops
$392American Airlines
Fri, May 15 - Sun, May 17
JetBlue Logo
5:59 pm - 1:35 am
CHS
-
STI
7h 36m
1 stop
JetBlue Logo
6:00 am - 4:57 pm
STI
-
CHS
10h 57m
1 stop
$395JetBlue
Sat, May 16 - Mon, May 18
American Airlines Logo
1:18 pm - 12:23 pm
CHS
-
STI
23h 05m
1 stop
American Airlines Logo
1:32 pm - 10:34 am
STI
-
CHS
21h 02m
1 stop
$399American Airlines
Fri, May 15 - Sun, May 17
American Airlines Logo
4:46 pm - 12:23 pm
CHS
-
STI
19h 37m
2 stops
American Airlines Logo
1:32 pm - 10:34 am
STI
-
CHS
21h 02m
1 stop
$400American Airlines
Sat, May 16 - Mon, May 18
Delta Logo
5:55 pm - 12:59 am
CHS
-
STI
7h 04m
1 stop
Delta Logo
8:59 pm - 12:12 pm
STI
-
CHS
15h 13m
1 stop
$403Delta
Sat, May 16 - Mon, May 18
JetBlue Logo
5:59 pm - 1:35 am
CHS
-
STI
7h 36m
1 stop
JetBlue Logo
6:00 am - 4:57 pm
STI
-
CHS
10h 57m
1 stop
$412JetBlue
Fri, Jun 5 - Tue, Jun 9
Delta Logo
6:00 am - 7:28 pm
CHS
-
STI
13h 28m
1 stop
Delta Logo
8:50 pm - 11:24 am
STI
-
CHS
14h 34m
2 stops
$413Delta
Sat, May 9 - Wed, May 13
JetBlue Logo
11:00 am - 10:26 pm
CHS
-
STI
11h 26m
1 stop
JetBlue Logo
8:31 am - 7:13 pm
STI
-
CHS
10h 42m
1 stop
$416JetBlue
Booking Insights

KAYAK's insights & trends for Charleston to Santiago de los Caballeros flights

Get data-powered insights and trends into flights from Charleston to Santiago de los Caballeros to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Charleston to Santiago de los Caballeros?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Charleston to Santiago de los Caballeros were found on Spirit Airlines ($369) and JetBlue ($379).

Find deals

Good to know

Cheapest flight$379
Flight from Charleston to Santiago de los Caballeros

When to book flights from Charleston to Santiago de los Caballeros

Are your dates flexible? Find out the best times to travel from Charleston to Santiago de los Caballeros based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Charleston to Santiago de los Caballeros

  • What is the cheapest flight from Charleston to Santiago de los Caballeros?

    In the last 3 days, the lowest price for a flight from Charleston to Santiago de los Caballeros was $369 for a round-trip ticket.

  • Do I need a passport to fly between Charleston and Santiago de los Caballeros?

    Yes, you’ll need a passport to travel to Santiago de los Caballeros from Charleston.

  • Which airports will I be using when flying from Charleston to Santiago de los Caballeros?

    When flying out of Charleston you will be using Charleston. You will be landing at Santiago de los Caballeros, also known as Santiago de los Caballeros.

  • Which aircraft models fly most regularly from Charleston to Santiago de los Caballeros?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Charleston to Santiago de los Caballeros?

    oneworld is the only airline alliance operating flights between Charleston and Santiago de los Caballeros.

  • How does KAYAK find such low prices on flights from Charleston to Santiago de los Caballeros?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to Santiago de los Caballeros.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to Santiago de los Caballeros?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago de los Caballeros from Charleston is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to Santiago de los Caballeros?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago de los Caballeros with an airline and back to Charleston with another airline. Booking your flights between Charleston and STI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to Santiago de los Caballeros?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago de los Caballeros from Charleston up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to Santiago de los Caballeros

 
See real verified KAYAK customer reviews for airlines flying from Charleston to Santiago de los Caballeros. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Charleston to Santiago de los Caballeros? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11468 reviews
6.9Entertainment
6.4Food
7.5Boarding
7.9Crew
7.2Comfort
Airline reviews

Not really sure I enjoyed the flight at all. The flight attendants seemed a little tired and rude at times. The snacks were lacking in taste and sustenance. The flight was incredibly turbulent for three plus hours and the pilot had to do a second pass to land at our final destination because he was coming in so fast. He must have taken a short cut and because of it we had to suffer the violent turbulence and the dropping down. It had to be one of if not the worse flights I have ever been on and have traveled vastly all over the world.

2.0 MediocreStarlite, Mar 2026
JFK - ANU
Read more American Airlines reviews

Not really sure I enjoyed the flight at all. The flight attendants seemed a little tired and rude at times. The snacks were lacking in taste and sustenance. The flight was incredibly turbulent for three plus hours and the pilot had to do a second pass to land at our final destination because he was coming in so fast. He must have taken a short cut and because of it we had to suffer the violent turbulence and the dropping down. It had to be one of if not the worse flights I have ever been on and have traveled vastly all over the world.

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

It would have been nice if American tried to care.

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

I booked 1st class, my flights were changed and I was sitting in the middle at the back of the plane. A far cry from the 1st class I purchased for my flights. I am grateful I arrived on time.

Aging planer and NO wifi on a 14 hour day flight. Unless you are retired or don't need to work or be in touch with the world... The lack of Wifif really ruined the flight. And the old plane - really showing it's age, wasn't great

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

Everything you need to know for your flight from Charleston to Santiago de los Caballeros

Information on your arrival and departure airports

Charleston (CHS)
Santiago de los Caballeros (STI)