$424 Find Cheap Flights from Charleston to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Sat, Sep 26 - Wed, Sep 30
United Airlines Logo
5:59 pm - 9:10 pm
CRW
-
MDE
28h 11m
2 stops
United Airlines Logo
9:45 am - 2:19 pm
MDE
-
CRW
27h 34m
2 stops
$424United Airlines
Sun, Sep 27 - Wed, Sep 30
United Airlines Logo
5:59 pm - 9:10 pm
CRW
-
MDE
28h 11m
2 stops
United Airlines Logo
9:45 am - 2:19 pm
MDE
-
CRW
27h 34m
2 stops
$491United Airlines
Fri, Sep 4 - Mon, Sep 14
United Airlines Logo
5:59 pm - 9:10 pm
CRW
-
MDE
28h 11m
2 stops
United Airlines Logo
9:45 am - 9:26 am
MDE
-
CRW
22h 41m
2 stops
$530United Airlines
Fri, Sep 4 - Mon, Sep 14
United Airlines Logo
5:59 pm - 9:10 pm
CRW
-
MDE
28h 11m
2 stops
United Airlines Logo
9:45 am - 9:26 am
MDE
-
CRW
22h 41m
2 stops
$609United Airlines
Mon, Jun 15 - Mon, Jun 22
Delta Logo
6:55 pm - 8:20 pm
CRW
-
LIM
26h 25m
2 stops
Delta Logo
8:55 am - 10:24 am
LIM
-
CRW
24h 29m
2 stops
$715Delta
Mon, Jun 15 - Mon, Jun 22
Multiple Airlines Logo
2:42 pm - 5:00 am
CRW
-
LIM
15h 18m
2 stops
Multiple Airlines Logo
12:05 pm - 10:24 am
LIM
-
CRW
21h 19m
1 stop
$1,157Multiple Airlines
Mon, Jun 15 - Mon, Jun 22
Multiple Airlines Logo
6:55 pm - 5:00 am
CRW
-
LIM
11h 05m
1 stop
Multiple Airlines Logo
12:05 pm - 10:24 am
LIM
-
CRW
21h 19m
1 stop
$1,986Multiple Airlines
Mon, Jun 15 - Sun, Jun 21
United Airlines Logo
11:00 am - 11:00 pm
CRW
-
LIM
13h 00m
2 stops
United Airlines Logo
12:55 am - 8:42 pm
LIM
-
CRW
18h 47m
3 stops
$6,426United Airlines
Sun, Jun 14 - Sat, Jun 20
United Airlines Logo
5:47 pm - 11:26 pm
CRW
-
SCL
53h 39m
2 stops
United Airlines Logo
12:38 am - 10:53 pm
SCL
-
CRW
22h 15m
2 stops
$25,037United Airlines
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Charleston to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Charleston to South America were found on United Airlines ($424) and Delta ($715).

Find deals

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8463 reviews
7.8Entertainment
7.9Comfort
8.1Boarding
7.2Food
8.5Crew
Airline reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

8.0 ExcellentMatthew, May 2026
OKC - ATL
Read more Delta reviews

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Charleston (CRW)