$431 Find Cheap Flights from Charleston to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Thu, May 7 - Thu, May 14
United Airlines Logo
5:50 pm - 9:10 pm
CRW
-
MDE
28h 20m
2 stops
United Airlines Logo
9:45 am - 10:49 pm
MDE
-
CRW
36h 04m
2 stops
$431United Airlines
Tue, May 12 - Sat, May 16
United Airlines Logo
6:45 am - 9:10 pm
CRW
-
MDE
15h 25m
2 stops
United Airlines Logo
9:45 am - 9:31 am
MDE
-
CRW
22h 46m
2 stops
$450United Airlines
Tue, May 12 - Sat, May 16
United Airlines Logo
5:50 pm - 9:10 pm
CRW
-
MDE
28h 20m
2 stops
United Airlines Logo
9:45 am - 9:31 am
MDE
-
CRW
22h 46m
2 stops
$487United Airlines
Tue, May 12 - Sat, May 16
United Airlines Logo
6:45 am - 9:10 pm
CRW
-
MDE
15h 25m
2 stops
United Airlines Logo
9:45 am - 9:31 am
MDE
-
CRW
22h 46m
2 stops
$524United Airlines
Fri, Sep 4 - Mon, Sep 14
American Airlines Logo
6:00 am - 11:35 pm
CRW
-
MDE
18h 35m
2 stops
American Airlines Logo
5:50 am - 10:08 pm
MDE
-
CRW
15h 18m
2 stops
$530American Airlines
Fri, Sep 4 - Mon, Sep 14
American Airlines Logo
6:00 am - 11:35 pm
CRW
-
MDE
18h 35m
2 stops
American Airlines Logo
5:50 am - 10:08 pm
MDE
-
CRW
15h 18m
2 stops
$547American Airlines
Fri, Sep 4 - Mon, Sep 14
United Airlines Logo
5:59 pm - 9:10 pm
CRW
-
MDE
28h 11m
2 stops
United Airlines Logo
9:45 am - 9:26 am
MDE
-
CRW
22h 41m
2 stops
$679United Airlines
Mon, May 4 - Sun, May 10
United Airlines Logo
5:50 pm - 11:00 pm
CRW
-
LIM
30h 10m
2 stops
United Airlines Logo
12:55 am - 10:49 pm
LIM
-
CRW
44h 54m
2 stops
$732United Airlines
Mon, May 4 - Sun, May 10
Delta Logo
11:10 am - 8:05 am
CRW
-
LIM
21h 55m
2 stops
Delta Logo
12:05 am - 11:07 pm
LIM
-
CRW
22h 02m
1 stop
$775Delta
Sat, Aug 29 - Sat, Sep 5
Delta Logo
6:00 am - 8:20 pm
CRW
-
LIM
15h 20m
2 stops
Delta Logo
8:55 am - 2:43 pm
LIM
-
CRW
28h 48m
2 stops
$805Delta
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Charleston to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Charleston to South America were found on United Airlines ($431) and American Airlines ($530).

Find deals

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8320 reviews
8.5Crew
8.1Boarding
7.2Food
7.8Entertainment
7.9Comfort
Airline reviews

The cabin temperature was nice and cool. The wifi was not working.

8.0 ExcellentMatt, Mar 2026
SEA - SJC
Read more Delta reviews

The cabin temperature was nice and cool. The wifi was not working.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

As previously noted, this flight was great: departure was timely, the crew was friendly and attentive, and wifi connectivity was seamless. In particular, I appreciated that the flight attendant just told me to stow the laptop right before takeoff/landing, and trusted me to do so (which I did!).

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

Entertainment is ok! Boarding and seat with zone is terrible. I paid for the seats but you didn’t give me what I paid for which is exit isles.

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Charleston (CRW)