$315 Find Cheap Flights from Charleston to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Mo, Feb 2 - Do, Feb 5
United Airlines Logo
5:37 pm - 10:05 pm
CRW
-
MDE
28h 28m2 stops
United Airlines Logo
10:45 am - 8:56 pm
MDE
-
CRW
34h 11m2 stops
$315United Airlines
Mo, Feb 2 - Do, Feb 5
United Airlines Logo
5:37 pm - 10:05 pm
CRW
-
MDE
28h 28m2 stops
United Airlines Logo
10:45 am - 8:56 pm
MDE
-
CRW
34h 11m2 stops
$333United Airlines
So, Jan 25 - Do, Jan 29
United Airlines Logo
5:37 pm - 10:05 pm
CRW
-
MDE
28h 28m2 stops
United Airlines Logo
10:45 am - 5:02 pm
MDE
-
CRW
30h 17m2 stops
$498United Airlines
So, Feb 8 - Mi, Feb 11
United Airlines Logo
6:50 am - 11:55 pm
CRW
-
LIM
41h 05m2 stops
United Airlines Logo
1:50 am - 8:58 pm
LIM
-
CRW
19h 08m2 stops
$680United Airlines
Sa, Jan 31 - Mi, Feb 4
United Airlines Logo
6:50 am - 11:55 pm
CRW
-
LIM
17h 05m2 stops
United Airlines Logo
11:55 pm - 8:56 pm
LIM
-
CRW
21h 01m2 stops
$775United Airlines
Mi, Mai 13 - Mi, Mai 20
Delta Logo
11:00 am - 2:05 pm
CRW
-
SCL
27h 05m2 stops
Delta Logo
8:40 pm - 10:28 am
SCL
-
CRW
13h 48m1 stop
$784Delta
Mi, Mai 13 - Mi, Mai 20
Delta Logo
11:00 am - 6:55 am
CRW
-
SCL
19h 55m2 stops
Delta Logo
11:25 pm - 10:41 pm
SCL
-
CRW
23h 16m2 stops
$789Delta
Do, Jan 22 - Mo, Jan 26
United Airlines Logo
6:50 am - 8:50 am
CRW
-
SCL
24h 00m2 stops
United Airlines Logo
10:45 pm - 5:02 pm
SCL
-
CRW
20h 17m2 stops
$7,139United Airlines
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Charleston and South America?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Charleston to South America.

There is just one airline that flies from Charleston to South America direct and that is Delta. The best round-trip deal found from Delta for the route is to Lima (LIM) and costs $594.

Which airlines provide the cheapest flights from Charleston to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Charleston to South America were found on United Airlines ($315) and Delta ($784).

Find deals

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8018 reviews
7.9Entertainment
7.3Food
8.5Crew
8.1Boarding
7.9Comfort
Airline reviews

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

4.0 OkayEmily, Dec 2025
LAX - ATL
Read more Delta reviews

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

Wasn't a Delta issue I don't think, but seems there was a Delta flight at each of the 2 Dallas airports at the same exact time, both to Atlanta. I was evidently booked on the one at Love Airport, but the Carey transport shuttle took me to DFW instead and I ended up missing the flight by just a few minutes. Was able to book a Southwest flight from Love Airport, but was a big loss of time and an inconvenience.

Great. I had to modify a flight. That was easy and free. Thank You

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

None of the airplane features were available during the flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

Lady Pilot was perfect in every way wheels up to wheels down communication, professionalism, excellent on time departure and on time arrival, excellent communication! Fantastic job with Superb attitude!!

The food is terrible. The staff is wonderful. Comfort is good.

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Everything you need to know for your flight to South America

Information on your arrival and departure airports

Charleston (CRW)