$548 Find Cheap Flights from Charleston to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Tue, May 19 - Tue, May 26
American Airlines Logo
6:12 pm - 12:48 pm
CRW
-
MDE
19h 36m
2 stops
American Airlines Logo
11:59 pm - 9:56 pm
MDE
-
CRW
20h 57m
2 stops
$548American Airlines
Fri, Sep 4 - Mon, Sep 14
American Airlines Logo
7:51 pm - 12:50 pm
CRW
-
MDE
17h 59m
2 stops
American Airlines Logo
5:50 am - 10:08 pm
MDE
-
CRW
15h 18m
2 stops
$683American Airlines
Fri, Sep 4 - Mon, Sep 14
United Airlines Logo
5:59 pm - 9:10 pm
CRW
-
MDE
28h 11m
2 stops
United Airlines Logo
9:45 am - 9:26 am
MDE
-
CRW
22h 41m
2 stops
$707United Airlines
Sun, May 3 - Fri, May 8
Delta Logo
7:20 pm - 8:20 pm
CRW
-
LIM
26h 00m
2 stops
Delta Logo
8:55 am - 10:32 am
LIM
-
CRW
24h 37m
2 stops
$891Delta
Sun, Apr 19 - Wed, Apr 22
Multiple Airlines Logo
9:59 am - 1:05 pm
CRW
-
SCL
27h 06m
2 stops
Multiple Airlines Logo
2:30 am - 8:12 pm
SCL
-
CRW
17h 42m
2 stops
$1,118Multiple Airlines
Tue, May 19 - Tue, May 26
United Airlines Logo
6:45 am - 11:00 pm
CRW
-
LIM
41h 15m
2 stops
United Airlines Logo
11:05 pm - 10:53 pm
LIM
-
CRW
22h 48m
2 stops
$1,174United Airlines
Sun, May 3 - Sun, May 10
LATAM Airlines Logo
7:20 pm - 6:00 am
CRW
-
SCL
34h 40m
2 stops
LATAM Airlines Logo
7:55 pm - 2:50 pm
SCL
-
CRW
18h 55m
2 stops
$1,329LATAM Airlines
Sun, May 3 - Sun, May 10
LATAM Airlines Logo
7:20 pm - 7:15 am
CRW
-
SCL
11h 55m
1 stop
LATAM Airlines Logo
7:55 pm - 2:50 pm
SCL
-
CRW
18h 55m
2 stops
$1,374LATAM Airlines
Sun, May 3 - Sun, May 10
Delta Logo
11:10 am - 7:15 am
CRW
-
SCL
20h 05m
1 stop
Delta Logo
7:55 pm - 11:07 pm
SCL
-
CRW
27h 12m
2 stops
$1,395Delta
Wed, Sep 23 - Thu, Sep 24
Multiple Airlines Logo
3:25 pm - 6:55 am
CRW
-
SCL
14h 30m
2 stops
Multiple Airlines Logo
9:25 pm - 10:26 am
SCL
-
CRW
38h 01m
2 stops
$1,513Multiple Airlines
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Charleston to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Charleston to South America were found on American Airlines ($548) and United Airlines ($707).

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8388 reviews
8.5Crew
7.9Comfort
7.8Entertainment
8.1Boarding
7.2Food
Airline reviews

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

10.0 ExcellentSarah, Apr 2026
LAX - SFO
Read more Delta reviews

Generally on time departures and arrivals, clean planes, sky miles membership provides great benefits (complimentary upgrades, etc).

Flight from Fort Wayne to Atlanta was the smallest in terms of cabin space that I've ever seen. A carry on I've used for 20 years BARELY fit in overhead compartment. I'm 5'10" and felt very cramped. Not the best experience.

I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.

We departed and landed early which was a nice surprise. The boarding process was slow.

N Everything was perfect from boarding to assistance to baggage in Tampa

Subpar. The seating on the plane is almost unbearable. We are literally touching and/or sitting on each other which is totally unacceptable and shameful. Pilots and crew was very accommodating and friendly.

The boarding was organized and informative but the plane was tight meaning that you were sitting on one another and extremely uncomfortable. It’s disappointing that can’t have common seating comfort on the plane.

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

I was told that they needed to check my bag at the gate and to pick it up at the gate in Richmond. No big deal. I know they can't control the weather, but we flew around RIC for 45 minutes to avoid the storm and were 25 minutes late leaving as well. Once we landed, we were told to go to baggage claim to pick up our luggage. I went to bathroom, paid for parking, and went to the assigned baggage claim location. United flight people came down with us as well. They got their luggage immediately. Next, South West people came down about 10 minutes later. They got their luggage next. We finally got our luggage around 30 minutes in waiting. Was not a wonderful experience. No reflection on Delta, but the ground crew was lousy at best.

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

Everything you need to know for your flight to South America

Information on your arrival and departure airports