$342 Find Cheap Flights from Charleston to South America

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charleston to South America departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Charleston to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charleston to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charleston to South America

Wed, Sep 9 - Wed, Sep 16
United Airlines Logo
6:05 pm - 9:10 pm
CRW
-
MDE
28h 05m
2 stops
United Airlines Logo
9:45 am - 9:24 am
MDE
-
CRW
22h 39m
2 stops
$342United Airlines
Wed, Sep 9 - Wed, Sep 16
United Airlines Logo
6:05 pm - 9:10 pm
CRW
-
MDE
28h 05m
2 stops
United Airlines Logo
9:45 am - 9:24 am
MDE
-
CRW
22h 39m
2 stops
$352United Airlines
Sun, Jul 26 - Sat, Aug 1
American Airlines Logo
6:35 am - 11:48 pm
CRW
-
MDE
18h 13m
2 stops
American Airlines Logo
12:30 am - 7:36 pm
MDE
-
CRW
18h 06m
2 stops
$570American Airlines
Fri, Sep 4 - Mon, Sep 14
United Airlines Logo
6:05 pm - 9:10 pm
CRW
-
MDE
28h 05m
2 stops
United Airlines Logo
9:45 am - 9:45 am
MDE
-
CRW
23h 00m
2 stops
$600United Airlines
Fri, Sep 4 - Mon, Sep 14
United Airlines Logo
6:05 pm - 9:10 pm
CRW
-
MDE
28h 05m
2 stops
United Airlines Logo
9:45 am - 9:45 am
MDE
-
CRW
23h 00m
2 stops
$610United Airlines
Mon, Dec 7 - Fri, Dec 11
LATAM Airlines Logo
6:40 pm - 5:00 am
CRW
-
LIM
10h 20m
1 stop
LATAM Airlines Logo
11:40 pm - 10:24 am
LIM
-
CRW
10h 44m
1 stop
$823LATAM Airlines
Mon, Dec 7 - Thu, Dec 10
LATAM Airlines Logo
6:00 am - 10:00 pm
CRW
-
LIM
16h 00m
2 stops
LATAM Airlines Logo
12:15 am - 10:39 pm
LIM
-
CRW
22h 24m
2 stops
$828LATAM Airlines
Mon, Dec 7 - Fri, Dec 11
LATAM Airlines Logo
6:00 am - 9:20 pm
CRW
-
LIM
15h 20m
1 stop
LATAM Airlines Logo
11:40 pm - 2:41 pm
LIM
-
CRW
15h 01m
1 stop
$879LATAM Airlines
Sun, Jul 26 - Sun, Aug 2
Multiple Airlines Logo
2:45 pm - 3:45 pm
CRW
-
MDE
26h 00m
1 stop
Multiple Airlines Logo
1:00 pm - 10:19 am
MDE
-
CRW
20h 19m
2 stops
$1,081Multiple Airlines
Sun, Jul 26 - Sun, Aug 2
United Airlines Logo
7:00 am - 9:10 pm
CRW
-
MDE
15h 10m
3 stops
United Airlines Logo
9:45 am - 10:25 am
MDE
-
CRW
23h 40m
2 stops
$5,680United Airlines
Booking Insights

KAYAK's insights & trends for Charleston to South America flights

Get data-powered insights and trends into flights from Charleston to South America to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Charleston to South America?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Charleston to South America were found on United Airlines ($342) and American Airlines ($570).

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charleston to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charleston to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charleston to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charleston to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charleston to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charleston to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charleston to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charleston to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Charleston to South America

 
Need help choosing which airline to fly with from Charleston to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8455 reviews
8.1Boarding
7.8Entertainment
7.2Food
8.5Crew
7.8Comfort
Airline reviews

It was as good as it could be. Flying is not a pleasant experience these days.

8.0 ExcellentMark, Jun 2026
LAX - ORD
Read more Delta reviews

It was as good as it could be. Flying is not a pleasant experience these days.

The plane was old and thus the seats were not good. No cushion left whatsoever, and it all was a bit worn out.

I was in Comfort and we didn’t get any drinks, chips or anything! First Class got full service on the flight and Comfort got nothing. Seat was horrible and uncomfortable

My flight was delayed by 4 hours in 30 minute increments. The gate agents were amazing but the communication was not. We were told that there was a maintenance issue but they didn't know what it was. That didn't inspire confidence. Then they said they found it and it was fixed and the pilot just needed to sign off. Then the pilot needed to talk to the other pilot from the arriving flight and we'd be fine. Then we were waiting for the pilot to call back. Then the maintenance issue wasn't fixed. Then they decided we were getting a new plane (why didn't they decide this earlier??). Fine. But then they announced we were changing gates AND terminals. And we were boarding in 20 minutes. So we all had to run to the new terminal gate. We could have taken off at that time, but we then had to wait for all the people who rebooked on a different flight to book this flight again. That took 30+ minutes because there was only one gate agent. When everyone ditched this flight, I saw it as an opportunity to upgrade to comfort. Delta, the greedy jerks they are, charged me $121. After their delay, their fault, their issues, couldn't even discount an upgrade. They only handed out $12 meal vouchers for the delay. I can't even get a snack from starbucks for that.

The crew was very inconsiderate and rude. My flight was scheduled to depart at 6:00am. I received a call from the crew at 5:40am, asking if I was going to make the flight because I was the only one that hasn't boarded yet and boarding ends at 5:50am. I let them know that I will be at the gate in a few minutes, before the 5:50am cutoff. When I arrived at the gate at 5:45am the gate was closed. Departing early on last minute notice without having all passengers on board is inconsiderate and unprofessional.

FA was a bit strange and dodgy not very characteristic of Delta

Not really a “Delta” problem but worth mentioning: Boarding was a difficult process. TSA seemed understaffed and Pre-Check took longer than regular TSA. The supervisor was frazzled and yelled at travelers. Once through TSA, we had to put our carry-ons through another x-ray machine. Then queue up to board with both boarding pass and ID. Then, when we got to the stairs on the tarmac, we had to show our boarding pass again. Maybe this is just normal for Kona since the terminal is outdoors (but still a “secured” area).

flight was delayed 4+ hours. there was really no understanding of why? weather? the last hour of delay was post boarding. pilot seat was broken. was that the real reason? nonetheless, long day of inconveniences.

Love me some Delta. One of the few airlines to recognize and support veterans. Easy boarding, flight was on time and arrived early and the flight attendants were excellent on this flight.

Typically I give delta excellent reviews. Our flight was delayed 2hrs, I was one of the fortunate ones who were able to get to my connecting flight. Also, annoying that on the connecting flight boarding personnel make me put away a small bag into my carryon. It small enough to put in back pocket seat, why hold me and the line up to just push it into my carryon.

Everything you need to know for your flight to South America

Information on your arrival and departure airports