$221 Find Cheap Flights from Charlotte to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charlotte to Panama departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charlotte to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City2 stops$388
Panama City
Panama City2 stops$388

Book Cheap Charlotte to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charlotte to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charlotte to Panama

Wed, Oct 22 - Sun, Oct 26
Multiple Airlines Logo
5:45 am - 12:45 amCLT-PTY
20h 00m2 stops
Multiple Airlines Logo
2:55 am - 8:59 pmPTY-CLT
17h 04m2 stops
$388Multiple Airlines
Find Deal
Thu, Oct 30 - Thu, Nov 6
Multiple Airlines Logo
1:49 pm - 8:37 pmCLT-PTY
7h 48m1 stop
Multiple Airlines Logo
8:25 am - 4:01 pmPTY-CLT
7h 36m1 stop
$392Multiple Airlines
Find Deal
Mon, Oct 20 - Wed, Oct 22
Delta Logo
5:30 am - 12:56 pmCLT-PTY
8h 26m1 stop
Delta Logo
2:21 pm - 11:50 pmPTY-CLT
8h 29m1 stop
$395Delta
Find Deal
Thu, Oct 30 - Thu, Nov 6
United Airlines Logo
6:45 am - 1:45 pmCLT-PTY
8h 00m1 stop
United Airlines Logo
8:55 am - 9:36 pmPTY-CLT
12h 41m1 stop
$399United Airlines
Find Deal
Mon, Oct 20 - Thu, Oct 23
American Airlines Logo
10:25 pm - 2:03 pmCLT-PTY
16h 38m1 stop
American Airlines Logo
3:15 pm - 7:50 amPTY-CLT
15h 35m2 stops
$400American Airlines
Find Deal
Fri, Dec 5 - Fri, Dec 12
American Airlines Logo
5:15 am - 1:47 pmCLT-PTY
8h 32m1 stop
American Airlines Logo
4:37 pm - 9:15 amPTY-CLT
16h 38m1 stop
$403American Airlines
Find Deal
Thu, Oct 9 - Wed, Oct 15
American Airlines Logo
10:25 pm - 2:03 pmCLT-PTY
16h 38m1 stop
American Airlines Logo
3:15 pm - 8:25 amPTY-CLT
16h 10m1 stop
$404American Airlines
Find Deal
Fri, Dec 5 - Fri, Dec 12
American Airlines Logo
6:55 am - 1:47 pmCLT-PTY
6h 52m1 stop
American Airlines Logo
4:37 pm - 6:29 amPTY-CLT
13h 52m2 stops
$408American Airlines
Find Deal
Sat, Oct 25 - Tue, Oct 28
Delta Logo
6:15 am - 12:56 pmCLT-PTY
7h 41m1 stop
Delta Logo
2:21 pm - 11:50 pmPTY-CLT
8h 29m1 stop
$415Delta
Find Deal
Sat, Oct 25 - Mon, Nov 3
United Airlines Logo
7:00 am - 2:14 pmCLT-PTY
8h 14m1 stop
United Airlines Logo
8:55 am - 9:36 pmPTY-CLT
12h 41m1 stop
$419United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Charlotte to Panama flights

Get data-powered insights and trends into flights from Charlotte to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charlotte to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charlotte to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charlotte to Panama is October, when tickets cost $510 (return) on average. On the other hand, the most expensive months are December and June, when the average cost of round-trip tickets is $946 and $597 respectively.

What’s the cheapest day of the week to fly from Charlotte to Panama?

The average price of all round-trip flights from Charlotte to Panama clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Panama on a Wednesday, as we generally find the cheapest rates on that day for this route. On the other hand, Saturday is the most expensive day to fly from Charlotte to Panama. For your return ticket, we recommend flying on a Wednesday and avoiding Fridays for the best deals.

How far in advance should I book a flight from Charlotte to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Charlotte to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Charlotte to Panama, you should book around 4 weeks before departure, which saves you about 24% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 8 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$221
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Charlotte to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Charlotte to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charlotte to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charlotte to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charlotte to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charlotte to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charlotte to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charlotte to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charlotte to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $478 on average. Morning departures are around 30% cheaper than evening flights, on average. The most expensive time of day to fly to Panama is generally in the evening, which is peak travel time and where the average cost of a ticket is $844.

Reviews of the top 3 airlines serving from Charlotte to Panama

 
Need help choosing which airline to fly with from Charlotte to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7957 reviews
7.9Entertainment
7.3Food
7.9Comfort
8.2Boarding
8.5Crew
Airline reviews

The staff and the boarding procedure were all amazing . The one flight was not equipped with WIFI which now adays seems odd. All in all the experience was good

8.0 ExcellentAnonymous, Sep 2025GFK - MSP
Read more Delta reviews

The staff and the boarding procedure were all amazing . The one flight was not equipped with WIFI which now adays seems odd. All in all the experience was good

Passengers need to check in big baggage instead of bringing on the plane. That cause inconvenience for everyone. Otherwise flight was good.

Perfect flight both ways. On time, courteous staff, plane comfortable and cool. Best domestic flights I’ve had in awhile.

The food was terrible especially for a 15 hour international flight. The crew was unpleasant as well.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Quick check in. Everything went smooth. I don't know what can be done about airline food.

Crew was good. The reservation got mixed up and they didn't have my TSA number. I am also a Silver Medallion and wasn't able to use Sky Priority.

Delta made it easy, comfortable and timely. The crew was fantastic.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

Terrible. They wouldn't allow me on my flight on the 14th..

We had to deboard 2 times due to maintenance issues. They changed the plane, and then we got deviated to LAX due to maibtenance issues on the other plane, had to sleep at LAX and los a full day.

Everything was good, except the seats in economy were so close together, you could barely get out when the seat in front of your was reclined. If the airlines keep jamming in more and more seats, it will become intolerable. I will look for another airline that considers customer comfort and does not keep adding more rows of seats for more profit.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Flight was good and crew was super polite. However, there were around 5 kids screaming the WHOLE 2 hours. I understand kids have to come but parents need to do something to control their children. They make the experience terrible, especially after finishing 16 hour shifts at the hospital I needed some sleep, which I did not get.

IAD with the archaic people movers is just a place to be avoided.

Great service on board. Boarding a bit slow due to process. Food was pretty average.

Tastless food and too obvious lack of enthusiasm for service in the economy vesus business class

All of the United employees I interacted with were professional and courteous. The aircraft was clean, the food on the flight was good. No complaints here.

I had no checked baggage but was required to hand over carry on baggage at the door of the plane. There was a lot of overboard space in the plane and I was one of the last ones. I ran to get my carry on but it was gone. I was given back at the plane door in Toronto, so the wait was not as long as it would have been at the carousel.

Boarding: Boarding was a bit of a mess. Our tickets indicated "BC" for Business Class, but we and many others were confused as that was not indicated anywhere in the airport, so we didn't know when we're supposed to board. The airplane: The airplane was nice. However, we sat near the back of the business class cabin and the flight attendants and passengers from other cabins would constantly move the curtain (which was very loud), preventing me from fallling asleep on my 8 hour flight. The flight crew: Amazing, generally. However, they nearly forgot to serve breakfast to me. The flight food: I was able to select my meal for dinner, which was really good. Breakfast was a bit of a mess, however. The crew forgot to serve me breakfast until the last minute. Very little was available by the time they remembered. The entertainment: Paltry, underwhelming, and dated. Not one new movie was available. Bottom line: For the money, you might want to consider other options for your international business class flights.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

Long 5 hour and 45 min flight and only one drink service and cookie snack

Newark airport grounded inbound flight and only announced when the flight was about to start taxing.

Was a normal flight but it was delayed, and there wasn't an explanation.

Terrible. The flight was delayed two hours due to weather. Then when we got on the plane, the first pilot ended up timing out and we had to wait for a second pilot. Second pile came on board and we tax it out. Had to return back to the gate because of an unruly passenger. Then the copilot timed out. Had to wait for new copilot. Also had to wait for maintenance to check for fuel. Then found out the second pilot timed out and we had to wait for a third pilot. Was ready to go and then needed maintenance again for another issue. In the end, it was 2 o’clock in the morning when they announced that the flight couldn’t go because the third pilot and the second copilot had timed out.

American Airlines initially postponed the flight. Then they cancelled it an rescheduled us on a flight that would take over 24 hours with multiple stops. They then changed this flight to a reasonable alternative the next day which they later cancelled and replaced with a flight that would take off with an additional 16 hour delay. They blamed weather but I noticed (at 4am) that Delta had direct flights from Charlotte to Detroit. I went on line. Booked it and was in Detroit buy 9am. The interesting thing is they did a similar thing to a family member just 2 days earlier. I don't think I will fly American unless I have to.

Everything you need to know for your flight from Charlotte to Panama

Information on your arrival and departure airports

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.