$157 Find Cheap Flights from Chicago to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Panama departing on 4/13. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Chicago to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Panama

Sun, Apr 12 - Thu, Apr 16
Multiple Airlines Logo
10:55 am - 2:15 pm
ORD
-
PTY
27h 20m
2 stops
Multiple Airlines Logo
4:25 am - 1:05 pm
PTY
-
ORD
32h 40m
2 stops
$400Multiple Airlines
Mon, Apr 27 - Fri, May 1
Multiple Airlines Logo
7:50 am - 9:15 am
ORD
-
PTY
25h 25m
2 stops
Multiple Airlines Logo
5:55 pm - 2:05 pm
PTY
-
ORD
20h 10m
2 stops
$407Multiple Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
4:51 pm - 2:15 pm
ORD
-
PTY
21h 24m
2 stops
Multiple Airlines Logo
4:25 am - 2:05 pm
PTY
-
ORD
33h 40m
2 stops
$409Multiple Airlines
Sat, Jun 13 - Sat, Aug 15
Copa Airlines Logo
3:21 pm - 9:03 am
ORD
-
DAV
17h 42m
1 stop
Copa Airlines Logo
9:50 am - 1:02 am
DAV
-
ORD
15h 12m
1 stop
$623Copa Airlines
Fri, Jun 5 - Sun, Jun 14
Copa Airlines Logo
3:21 pm - 9:03 am
ORD
-
DAV
17h 42m
1 stop
Copa Airlines Logo
9:50 am - 4:00 am
DAV
-
ORD
18h 10m
1 stop
$728Copa Airlines
Sat, Apr 25 - Sat, May 2
Copa Airlines Logo
3:05 pm - 9:08 am
ORD
-
DAV
18h 03m
1 stop
Copa Airlines Logo
9:38 am - 1:15 am
DAV
-
ORD
15h 37m
1 stop
$802Copa Airlines
Tue, Jun 2 - Mon, Jun 8
Copa Airlines Logo
8:51 am - 9:03 am
ORD
-
DAV
24h 12m
2 stops
Copa Airlines Logo
9:50 am - 12:45 am
DAV
-
ORD
14h 55m
2 stops
$1,087Copa Airlines
Tue, Jun 2 - Wed, Jun 10
United Airlines Logo
10:30 am - 9:03 am
ORD
-
DAV
22h 33m
2 stops
United Airlines Logo
9:50 am - 8:00 am
DAV
-
ORD
22h 10m
2 stops
$1,125United Airlines
Sat, Jun 13 - Sat, Aug 15
United Airlines Logo
8:51 am - 9:03 am
ORD
-
DAV
24h 12m
2 stops
United Airlines Logo
9:50 am - 12:48 am
DAV
-
ORD
14h 58m
2 stops
$1,140United Airlines
Fri, May 15 - Fri, May 22
United Airlines Logo
7:45 pm - 8:58 am
ORD
-
DAV
13h 13m
2 stops
United Airlines Logo
9:38 am - 8:42 am
DAV
-
ORD
23h 04m
2 stops
$1,149United Airlines
Booking Insights

KAYAK's insights & trends for Chicago to Panama flights

Get data-powered insights and trends into flights from Chicago to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Chicago found in the last 72 hours was to Panama City, at $322 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $322.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Chicago to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $486 on average. Morning departures are around 7% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $575.

Can I save money by flying with a layover from Chicago to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $507 on average.

What is the cheapest month to fly from Chicago to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Panama is July, when tickets cost $523 (return) on average. On the other hand, the most expensive months are May and January, when the average cost of round-trip tickets is $687 and $588 respectively.

What’s the cheapest day of the week to fly from Chicago to Panama?

The average price of all round-trip flights from Chicago to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Chicago to Panama, look for departures on Tuesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Panama, Wednesday is the cheapest day to fly and Sunday is the most expensive.

How far in advance should I book a flight from Chicago to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Panama, you should book around 2 weeks before departure, which saves you about 33% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$157
Best time to beat the crowds but there is an average 18% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Chicago O'Hare Airport to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Chicago to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from Chicago to Panama

 
Need help choosing which airline to fly with from Chicago to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8366 reviews
8.1Boarding
8.5Crew
7.9Comfort
7.8Entertainment
7.2Food
Airline reviews

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

8.0 ExcellentEarl, Apr 2026
ORD - DTW
Read more Delta reviews

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

Flight delayed. Air broken. Cabin was hot enough to pass out. Delta shuttle’s becoming worse and worse.

my mom urmila patel needed a wheelchair which was not available on the curbside. she needed to walk almost 50 meters inside (at the risk of falling) and then had to wait in line to get a wheelchair (this is not ok). Once obtained she had to seat in it for 30-45 minutes for someone to take her in thru the checkin process (which was fairly smooth and easy). the lady who helped her with her checkin process was very courteous and helpful

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Fast, lovely scenery, great info on the Delta flight screen about landmarks we were flying over. Great landing!

Staff at the check-in counter were friendly, happy and helpful. They tagged our bags and sent us to “bag drop off” but were not very clear about where that was. The airport was busy we headed off in what we thought was the right direction until a gentleman waved us down and actually came after us. He was the baggage handler for Delta and recognized our “deer in the headlights “ look-he brought us to the right area (which was marked as the Southwest Airlines Drop Off) and sent us on our way. Wonderful guy, low key and working with a big smile on his face. Loved it. Loved him.

During the flight, the only refreshments provided were crackers and soft drinks; no substantial food was offered despite the international route. Furthermore, our initial flight was delayed, causing us to miss the connecting flight in Atlanta. The airline did not hold the connection, and we were informed that the next available flight is not for another 24 hours. While I am aware of alternative options via JetBlue, they operate out of JFK, which is not a viable solution for us as a resident of New Jersey.

Arlene was a great flight attendant. I also liked how one of the other flight attendants gave us a heads up about snacks and asked everyone to remove their headphones when it was their turn to order. Good idea.

Long flight but comfortable and not freezing as I have experienced on Hawaiian flights to the islands. They gave us blankets just in case. Nice touch.

I haven’t flown economy in over 20 years but it was not bad. Room by my feet for my bag and seat was roomy enough. Surprised in a good way.

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

No meal service to the back of the plane as it started late or was too slow to get it out before it was time to land.

Terrible, if possible won't be flying again anytime soon!

Efficient boarding and early departure. Very smooth flight. Early arrival in ATL. Great flight.

Smooth and easy boarding, comfortable for the entire 5 hour flight, and the seat back entertainment was great! I appreciated all the features, from location info and maps, movies, the ability to connect with Bluetooth headphones, and good selection of movies. Food was good, normal airline snacks (I didn’t purchase anything)

Awful. No counter attendants. No dinner offered due to delays.

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The gate got changed several times and the flight was delayed over an hour. Awful experience

American continues to decline in their customer service and its beyond disappointing.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Maintenance took a very long time and then we were in a holding pattern. While a one-off maintenance issue is standard, there were delays on both of my flights for this trip based on maintenance issues with the planes, which delayed both flights over 45 minutes. Thankfully, I didn't have any connections but it wasn't an experience that would make me pick AA if I have other options.

No Snacks or Entertainment. The flight was short, snacks should still be given.

See prior comment about how Kayak mishandled my reservation and delayed my arrival by 6 hours.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I upgraded to businesses class. Because of that the flight was comfortable.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Everything you need to know for your flight from Chicago to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.