$296 Find Cheap Flights from Chicago to Panama - Compare and Save

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Cheap Flights from Chicago to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Sort by: Cheapest
Panama City
5h 21mNonstop
from $627per person
David
9h 08m3 stops
from $630per person
Booking Insights

Price, demand and travel trends for Chicago O'Hare Intl Airport to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Are flights from Chicago O'Hare Intl Airport to Panama cheaper or more expensive than last year?

Fares from Chicago O'Hare Intl Airport to Panama are running about 6% higher than they were around this time last year, averaging $635 round-trip.

What are the cheapest fares from Chicago O'Hare Intl Airport to Panama right now?

The cheapest fares from Chicago O'Hare Intl Airport to Panama on KAYAK in the last week were to Panama City Tocumen Intl (PTY) from $627 round-trip, and to David Enrique Malek (DAV) from $630 round-trip.

What’s the cheapest month to fly from Chicago O'Hare Intl Airport to Panama?

April is the cheapest time of year to fly, with average fares of $594. Prices are highest in December, when average flight costs increase to around $872.

When is the best time to book flights from Chicago O'Hare Intl Airport to Panama?

Book your flights 12 weeks before your trip. KAYAK data collected over the past 12 months shows that booking in this window can save you around 36% compared to booking last-minute (within 2 weeks of departure).

Which airport in Panama is the cheapest to fly to from Chicago O'Hare Intl Airport?

Based on KAYAK data from the past 12 months, the cheapest airports to fly into Panama are:

• Panama City Tocumen Intl (PTY) from $687
• David Enrique Malek (DAV) from $752

What’s the cheapest day to fly from Chicago O'Hare Intl Airport to Panama?

Thursday tends to be the cheapest day to fly from Chicago O'Hare Intl Airport to Panama, while Monday is the most expensive. Fares run about 13% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from Chicago O'Hare Intl Airport to Panama?

Data from the past 12 months shows it's cheapest to fly to Panama during the night with average prices of $376. The morning is the most expensive time to fly, with average prices of $719.

Key details for Chicago O'Hare Intl Airport to Panama flights

Low season

September

Cheapest flight

$296
Beat the crowds with an average 58% drop in travelers.
The most popular month to fly with an average 89% increase in travelers.
One-way flight from Chicago O'Hare Intl Airport to Panama City

Your Chicago O'Hare Intl Airport to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Chicago O'Hare Intl Airport to Panama?

    Fares from Chicago O'Hare Intl Airport to Panama are around their usual level right now. A round-trip under $580 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.

  • How much should I budget for a flight from Chicago O'Hare Intl Airport to Panama?

    Over the past 12 months, round-trip fares from Chicago O'Hare Intl Airport to Panama have ranged from $580 to $846.

  • What are the main airports serving Panama?

    Flights to Panama use two main airports, Panama City Tocumen Intl (PTY) and David Enrique Malek (DAV).

  • What airlines fly nonstop from Chicago O'Hare Intl Airport to Panama?

    Based on the flight schedule for the next 3 months, just one airline regularly flies nonstop from Chicago O'Hare Intl Airport to Panama: Copa Airlines.

  • Where in Panama can I fly nonstop from Chicago O'Hare Intl Airport?

    Based on the flight schedule for the next 3 months, you can only fly nonstop from Chicago O'Hare Intl Airport to Panama City.

  • Is it cheaper to fly with a layover from Chicago O'Hare Intl Airport to Panama?

    Yes. Nonstop flights from Chicago O'Hare Intl Airport to Panama average $692 over the past 12 months. Flights with a layover can cost less, cheapest when connecting through Bogotá El Dorado (BOG) from $397 or Fort Lauderdale (FLL) from $481.

  • How long is a flight from Chicago O'Hare Intl Airport to Panama?

    Flights from Chicago O'Hare Intl Airport to Panama take 5h 24m on average.

  • How often are flights from Chicago O'Hare Intl Airport to Panama delayed and what's the average delay?

    12% of flights on this route are delayed by at least 15 minutes. The average delay is 2h.

  • Which cabin classes are available on flights from Chicago O'Hare Intl Airport to Panama?

    On flights from Chicago O'Hare Intl Airport to Panama you can book Economy Class, Business Class or First Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

  • What are the earliest and latest flights from Chicago O'Hare Intl Airport to Panama?

    The earliest nonstop flight from Chicago O'Hare Intl Airport to Panama departs at 12:27 am and the latest departs at 3:20 pm. Nonstop flights take about 5h 24m.

Your guide to booking Chicago O'Hare Intl Airport to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If you can plan ahead, the sweet spot for booking your flight is 12 weeks before your trip. KAYAK data shows fares in this window are around 36% lower than last-minute bookings (made within 2 weeks of departure). Not ready to commit? Set a Price Alert and we'll let you know when prices change.
  • If your travel dates are flexible, book your trip for April when flights are typically cheapest and avoid December when prices are at their highest.
  • Flying on Thursday is usually the cheapest. Flights on Monday cost about 13% more on average, so being flexible with your travel dates could help you save.
  • If you're looking to save, Panama City Tocumen Intl (PTY) is the cheapest airport to fly into from Chicago O'Hare Intl Airport. If you have onward travel, don't forget to factor in the cost of your journey by train, bus or domestic flight.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.
  • If you want the shortest trip, choose the Chicago O'Hare Intl Airport to Panama nonstop route. If you'd rather save money, the route via Bogotá El Dorado (BOG) is usually the cheapest.

Reviews of the top 4 airlines serving from Chicago to Panama

 
Need help choosing which airline to fly with from Chicago to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1546 reviews
7.4Comfort
6.9Food
8.1Crew
6.9Entertainment
7.8Boarding
Airline reviews

It is not a good experience with Copa Airlines: flight delay, luggage delay, etc.

6.0 GoodAnonymous, Aug 2026
Read more Copa Airlines reviews

It is not a good experience with Copa Airlines: flight delay, luggage delay, etc.

We where skipped for this flight will not head to Panama until tonight..

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

On time. Carry on and personal bag was accommodated on the plane. Entertainment was accessible without bringing own device. Whole can of juice was provided rather than a pour.

Price was crazy watch it if you Chan he your flight

On time, easy boarding. Anytime you sit in an economy seat, it’s uncomfortable. New plane and the bathrooms were in the galley at the back of the plane which seemed odd.

Terrible service - they don’t want to be there and bad food. Entertainment system in economy from the 2000s

No drink service but there was no N/A as an option to choose. Seats were extremely tight. I am under 5.5 and I bumped my knees have no idea how taller people could manage.

Flight delayed, last seat on the plane, no arrival Gate available due to the plane departing late

Kayak booked this flight with only 1h 20min layover in Chicago. This made it impossible for me and several other passengers to reach this flight. Moreover, the gate closed boarding in spite of several passengers still on their way without waiting even one more minute. However, the plane departed with 20min (!) delay, i.e., there would have been at least 15 min time to let the delayed passengers board without causing any delays. I complained and as a "thank you" the attendent booked us on the last (!) flight to Indianapolis ~7h later! Thankfully, I caught the spitefulness and the United customer line rebooked the flight to an earlier flight. Although I can't grade this particular flight since I never had a chance to take it, Kayak made the mistake of a too short layover and the crew at the gate was awful.

Flight did not have wifi service. It was experiencing technical difficulties. Definitely and old plane that needs updating.

This flight has a history of leaving late, however, I was pleasantly surprised that it was not delayed this day. The flight went smooth, except I was in a window seat and the wall and my feet were freezing. I found it difficult to sleep due to being so cold, I also was using 2 provided UAL blankets and could not get my feet warm. This was annoying, but I still made it there on time and safe.

Old 757 with poor entertainment system. United no longer partners with United for free text and email. O'Hara an absolute disaster! Limited gates clauses two hour delay. Unfortunately this appears to be the norm.

First class snacks - stewardess gave out multiples to everyone until there was almost no selection left when she got back to me last in first class cabin. Nothing left that I would eat.

My feedback from the trip to Columbia to Chicago was meant for Chicago to Denver.

The WiFi was out gr entire flight. Had to Diane for almost 1 hour to wait for a gate to open up for plane to dock. Very bad experience.

After boarding, the AC was shut off on the flight. At business class, I really could not breathe. I was absolutely dripping sweat. I was told by the FA that there was nothing they could do but I could stand by the door until departure. So, that's what I did. I was clearly in the way while the FAs were trying to do their work, but I had to be able to breathe. After that, of course, I had sweated up a lot so was very uncomfortable for the six hour flight.

DELAYED AGAIN and AGAIN and AGAIN - not only that, you delay in 20 minute increments for hours and hours instead of having an accurate delay understanding.

AA was fine....the overall experience was subpar, but not due to the airline due to broader issues

No ground air conditioner for the plane. Very hot and humid prior to take off which was an uncomfortable period of time.

Check-in process was poor, very poor, only one person to check-in all passengers, so if one passenger had a check-in issue, all other passengers were delayed. All check-ins should have two airline staff to check-in passengers.

The flight up was great no issues. The flight back home was a cluster. I was told the plane I was waiting on was giving to another flight which caused me to miss my connection flight. Granted the airline did great with getting hotel and vouchr for food.

Flight was delayed and so much of inconvenience related to the gate change.

I like the attention you gave us in Guatemala due to the loss of the flight coming to El Salvador. It was a nice experience. Thanks a lot

We booked seats next to each other. When we got the boarding passes, they were for different rows. The crew were reluctant to help us, so we ended up sitting separately. 1. What’s the point of reserving by seat number if you’re not going to honor that reservation? 2. Even if it gets messed up between reservation and boarding, how is the crew going to deny us the opportunity to arrange to sit together. There were plenty of people flying alone. It could’ve been easily accommodated. Not very customer-friendly at all.

The seats were the worst I have ever flown Too narrow, did not recline and the actual seat was hard as a rock. I will tell all travelers to stay away from Avianca flights.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

More options for your flight from Chicago to Panama

Complete your trip to Panama with a hotel stay or car rental