Find Cheap Flights from Chicago to Panama

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Chicago to Panama

(Round-trip)
Depart: Wed Sep 20 2017 Return: Wed Sep 27 2017 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
PTY
7h 51m
1 stop
PTY
ORD
7h 50m
1 stop
Depart: Thu Oct 26 2017 Return: Mon Nov 6 2017 Trip spans 12 days
Aeromexico
Aeromexico
ORD
PTY
22h 35m
1 stop
PTY
ORD
31h 40m
1 stop
Depart: Tue Aug 22 2017 Return: Thu Aug 31 2017 Trip spans 10 days
Major Airline
Major Airline
ORD
PTY
5h 26m
nonstop
PTY
ORD
5h 39m
nonstop
Depart: Wed Jun 28 2017 Return: Thu Jun 29 2017 Trip spans 2 days
American Airlines
American Airlines
ORD
PTY
14h 40m
1 stop
PTY
ORD
12h 10m
1 stop
Depart: Mon Jul 17 2017 Return: Fri Jul 21 2017 Trip spans 5 days
Delta
Delta
MDW
PTY
9h 30m
1 stop
PTY
MDW
14h 37m
1 stop
Depart: Tue Dec 26 2017 Return: Sun Dec 31 2017 Trip spans 6 days
Copa Airlines
Copa Airlines
ORD
PTY
5h 22m
nonstop
PTY
ORD
5h 39m
nonstop
Depart: Mon Aug 14 2017 Return: Wed Aug 23 2017 Trip spans 10 days
Spirit Airlines
Spirit Airlines
ORD
PTY
8h 24m
1 stop
PTY
ORD
8h 54m
1 stop
Depart: Thu Aug 17 2017 Return: Sun Aug 20 2017 Trip spans 4 days
Aeromexico
Aeromexico
ORD
PTY
30h 45m
1 stop
PTY
ORD
31h 47m
1 stop
Depart: Mon Jul 31 2017 Return: Wed Aug 9 2017 Trip spans 10 days
Spirit Airlines
Spirit Airlines
ORD
PTY
8h 24m
1 stop
PTY
ORD
8h 54m
1 stop
Depart: Thu Nov 23 2017 Return: Mon Nov 27 2017 Trip spans 5 days
Major Airline
Major Airline
ORD
PTY
8h 38m
1 stop
PTY
ORD
5h 39m
nonstop
Depart: Wed Oct 4 2017 Return: Sat Oct 7 2017 Trip spans 4 days
Spirit Airlines
Spirit Airlines
ORD
PTY
7h 51m
1 stop
PTY
ORD
7h 50m
1 stop
Depart: Sat Aug 12 2017 Return: Fri Aug 18 2017 Trip spans 7 days
Major Airline
Major Airline
ORD
PTY
5h 26m
nonstop
PTY
ORD
5h 39m
nonstop
Depart: Thu Jun 29 2017 Return: Mon Jul 3 2017 Trip spans 5 days
American Airlines
American Airlines
ORD
PTY
8h 28m
1 stop
PTY
ORD
16h 49m
1 stop
Depart: Mon Jul 24 2017 Return: Thu Aug 3 2017 Trip spans 11 days
Delta
Delta
MDW
PTY
11h 20m
1 stop
PTY
MDW
9h 06m
1 stop
Depart: Mon Jul 24 2017 Return: Wed Aug 2 2017 Trip spans 10 days
Spirit Airlines
Spirit Airlines
ORD
PTY
17h 34m
1 stop
PTY
ORD
8h 54m
1 stop
Depart: Mon Jul 24 2017 Return: Mon Aug 14 2017 Trip spans 22 days
American Airlines
American Airlines
ORD
PTY
18h 12m
1 stop
PTY
ORD
8h 31m
1 stop
Depart: Tue Aug 1 2017 Return: Thu Aug 10 2017 Trip spans 10 days
Delta
Delta
MDW
PTY
7h 40m
1 stop
PTY
MDW
14h 37m
1 stop
Depart: Wed Nov 1 2017 Return: Wed Nov 8 2017 Trip spans 8 days
Major Airline
Major Airline
ORD
PTY
5h 26m
nonstop
PTY
ORD
5h 39m
nonstop
Depart: Thu Sep 7 2017 Return: Sun Sep 10 2017 Trip spans 4 days
Delta
Delta
MDW
PTY
9h 30m
1 stop
PTY
MDW
12h 47m
1 stop
Depart: Thu Dec 7 2017 Return: Sat Dec 16 2017 Trip spans 10 days
Major Airline
Major Airline
ORD
PTY
5h 26m
nonstop
PTY
ORD
5h 39m
nonstop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
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Airports
Origin

Chicago
only $372
only $630
Destination

Panama City
$372