$319 Find Cheap Flights from Chicago to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Panama departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Chicago to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Panama

Wed, Aug 19 - Sun, Aug 23
Multiple Airlines Logo
6:00 am - 9:15 am
MDW
-
PTY
27h 15m
3 stops
Multiple Airlines Logo
3:10 pm - 2:07 pm
PTY
-
MDW
22h 57m
3 stops
$603Multiple Airlines
Thu, Sep 10 - Mon, Sep 14
Multiple Airlines Logo
1:40 am - 9:15 am
ORD
-
PTY
31h 35m
3 stops
Multiple Airlines Logo
5:30 am - 5:52 am
PTY
-
ORD
24h 22m
3 stops
$704Multiple Airlines
Sat, Sep 19 - Fri, Oct 2
Copa Airlines Logo
8:01 am - 1:22 pm
ORD
-
PTY
5h 21mnonstop
Copa Airlines Logo
7:20 pm - 12:57 am
PTY
-
ORD
5h 37mnonstop
$733Copa Airlines
Sun, Nov 1 - Sun, Jan 24
Copa Airlines Logo
2:13 pm - 8:37 pm
ORD
-
PTY
5h 24mnonstop
Copa Airlines Logo
8:08 am - 12:46 pm
PTY
-
ORD
5h 38mnonstop
$737Copa Airlines
Wed, Jul 1 - Tue, Jul 7
Avianca Logo
11:20 pm - 5:00 pm
ORD
-
PTY
17h 40m
1 stop
Avianca Logo
4:25 am - 9:20 pm
PTY
-
ORD
16h 55m
1 stop
$738Avianca
Mon, Jul 27 - Mon, Aug 3
Avianca Logo
11:20 pm - 5:00 pm
ORD
-
PTY
17h 40m
1 stop
Avianca Logo
10:10 am - 9:20 pm
PTY
-
ORD
11h 10m
1 stop
$739Avianca
Sun, Oct 11 - Sat, Oct 31
Delta Logo
6:00 am - 12:56 pm
MDW
-
PTY
6h 56m
1 stop
Delta Logo
2:21 pm - 10:10 pm
PTY
-
MDW
7h 49m
1 stop
$752Delta
Thu, Sep 3 - Sun, Sep 6
Delta Logo
6:05 am - 12:55 pm
MDW
-
PTY
6h 50m
1 stop
Delta Logo
2:20 pm - 10:36 pm
PTY
-
MDW
8h 16m
1 stop
$760Delta
Fri, Aug 28 - Sun, Aug 30
United Airlines Logo
5:00 am - 9:08 am
ORD
-
DAV
28h 08m
2 stops
United Airlines Logo
9:50 am - 10:15 am
DAV
-
ORD
24h 25m
2 stops
$1,195United Airlines
Sat, Aug 15 - Tue, Aug 18
United Airlines Logo
3:55 pm - 9:08 am
ORD
-
DAV
17h 13m
2 stops
United Airlines Logo
9:50 am - 1:02 am
DAV
-
ORD
15h 12m
1 stop
$1,696United Airlines
Booking Insights

KAYAK's insights & trends for Chicago to Panama flights

Get data-powered insights and trends into flights from Chicago to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Chicago found in the last 5 days was to Panama City, at $406 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 5 days was $406.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Chicago to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $475 on average. Morning departures are around 2% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $584.

Can I save money by flying with a layover from Chicago to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $731 on average.

What is the cheapest month to fly from Chicago to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Panama is February, when tickets cost $102 (return) on average. On the other hand, the most expensive months are June and September, when the average cost of round-trip tickets is $536 and $450 respectively.

What’s the cheapest day of the week to fly from Chicago to Panama?

The average price of all round-trip flights from Chicago to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Chicago to Panama, look for departures on Wednesdays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from Panama, Saturday is the cheapest day to fly and Sunday is the most expensive.

How far in advance should I book a flight from Chicago to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Panama, you should book around 5 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$319
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Chicago O'Hare Airport to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Chicago to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Chicago to Panama

 
Need help choosing which airline to fly with from Chicago to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8403 reviews
8.5Crew
7.2Food
8.1Boarding
7.8Comfort
7.8Entertainment
Airline reviews

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

4.0 OkayMarilyn, Jun 2026
DEN - ATL
Read more Delta reviews

I have Precheck. Flew HPN to DEN and return this past weekend. Delta didn't attach my Precheck number to this trip. So it was waiting in general line especially in Denver. Unavailable.

Original flight was delayed, then cancelled and the gate staff did not expedite rebooking. Also, no instructions were given that a ticket number was needed before being called to facilitate rebooking. This could have been much more organized.

Be on time? When not on time a circling for over an hour offer more than 1 bag of chips to the passengers? It was a 7 hour flight by the time we got done.

Five hour delays every hour, I wish it were all at once

Flight delayed four separate times. I’m now one hour hours late to landing.

worst flight ever from Delta, it got delayed and kept on delaying..

Should never have had to go to Detroit from Orlando back to Tennessee!

Got rerouted from a straight flight from Orlando to Atlanta to Knoxville to a flight from Orlando to Detroit to Knoxville! Seriously!! Flight delay out of Detroit! Long day for what should have been a pretty easy travel day!

Two delays on two separate planes with parts they could not easily find and replace.

Checkin was good, fllight ws good. Onlly complaint is lack of foot on 6 hour flight from Seattle to Boston. Snacks were flimsy - chips and cookies. could have offered something more substantial for such a long flight. I know you can buy food in airport but for the price you pay for a ticket, they should step up for the passengers.

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

Smooth travel. Immediate update prior flight delay so I can arrange myself properly without too rush.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I upgraded to businesses class. Because of that the flight was comfortable.

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Everything you need to know for your flight from Chicago to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.