$174 Find Cheap Flights from Chicago to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Chicago to Panama departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy

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Cheap Flights from Chicago to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City1 stop$428
Panama City
Panama City1 stop$428

Book Cheap Chicago to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Chicago to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Chicago to Panama

Thu, Oct 16 - Tue, Oct 21
Avianca Logo
2:35 pm - 10:10 amORD-PTY
19h 35m1 stop
Avianca Logo
3:20 am - 1:15 pmPTY-ORD
9h 55m1 stop
$428Avianca
Find Deal
Wed, Sep 17 - Mon, Sep 22
 Logo
10:27 am - 7:29 pmORD-PTY
9h 02m1 stop
 Logo
9:33 pm - 9:18 amPTY-ORD
11h 45m1 stop
Wed, Nov 5 - Mon, Nov 10
Copa Airlines Logo
2:07 pm - 7:50 amORD-DAV
16h 43m1 stop
Copa Airlines Logo
8:32 am - 12:05 amDAV-ORD
16h 33m1 stop
$461Copa Airlines
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Fri, Sep 12 - Fri, Sep 19
Copa Airlines Logo
3:07 pm - 8:35 pmORD-PTY
5h 28mnonstop
Copa Airlines Logo
6:45 pm - 12:21 amPTY-ORD
5h 36mnonstop
$483Copa Airlines
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Wed, Oct 29 - Wed, Nov 5
Delta Logo
5:20 am - 12:56 pmORD-PTY
7h 36m1 stop
Delta Logo
3:21 pm - 11:57 pmPTY-ORD
9h 36m1 stop
$497Delta
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Wed, Oct 29 - Thu, Nov 6
Delta Logo
6:00 am - 12:56 pmMDW-PTY
6h 56m1 stop
Delta Logo
3:21 pm - 10:14 pmPTY-MDW
7h 53m1 stop
$497Delta
Find Deal
Thu, Oct 23 - Mon, Oct 27
American Airlines Logo
9:12 pm - 2:03 pmORD-PTY
16h 51m2 stops
American Airlines Logo
3:15 pm - 9:30 amPTY-ORD
18h 15m2 stops
$502American Airlines
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Thu, Oct 2 - Sun, Oct 5
American Airlines Logo
6:09 am - 2:31 pmORD-PTY
8h 22m1 stop
American Airlines Logo
3:31 pm - 8:18 amPTY-ORD
16h 47m2 stops
$507American Airlines
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Fri, Oct 3 - Fri, Oct 10
United Airlines Logo
6:00 am - 5:29 pmORD-DAV
11h 29m2 stops
United Airlines Logo
9:44 am - 12:14 amDAV-ORD
14h 30m2 stops
$922United Airlines
Find Deal
Thu, Feb 5 - Thu, Mar 5
United Airlines Logo
7:45 am - 9:04 amORD-DAV
24h 19m2 stops
United Airlines Logo
9:48 am - 8:32 pmDAV-ORD
35h 44m2 stops
$1,028United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Chicago to Panama flights

Get data-powered insights and trends into flights from Chicago to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Chicago found in the last 72 hours was to Panama City, at $311 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $311.

Can I save money by flying with a layover from Chicago to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 2 stops layover the cheapest option at $507 on average.

What is the cheapest month to fly from Chicago to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago to Panama is November, when tickets cost $464 (return) on average. On the other hand, the most expensive months are December and May, when the average cost of round-trip tickets is $750 and $656 respectively.

What’s the cheapest day of the week to fly from Chicago to Panama?

The average price of all round-trip flights from Chicago to Panama clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Chicago to Panama, look for departures on Tuesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama, Wednesday is the cheapest day to fly and Tuesday is the most expensive.

How far in advance should I book a flight from Chicago to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago to Panama, you should book around 2 weeks before departure, which saves you about 44% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$174
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Chicago O'Hare Airport to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Chicago to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $517 on average. Morning departures are around 6% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $608.

Reviews of the top 5 airlines serving from Chicago to Panama

 
Need help choosing which airline to fly with from Chicago to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 7982 reviews
7.9Entertainment
7.9Comfort
8.2Boarding
7.3Food
8.5Crew
Airline reviews

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

6.0 GoodKristopher, Aug 2025HPN - ATL
Read more Delta reviews

Three seats in first class were broken and while they were able to still acommodate us it was looking very touch and go and they had others they could not acommodate

Mechanic delay in addition to a 2 hour change in takeoff time was frustrating.

Delayed due to thunderstorms and no in-flight service due to rough weather — both of which are out of Delta’s control. Flight was good overall.

The flight attendants in SLC were rude. I arrived 40 minutes early to gate. Ticket said I needed check in for seat assignments and tried check in and attendants said they weren’t doing it. And proceeded to never call me to give me a ticket so when time to board I received the very last seat. Please relay to employees to do their job better..,

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

There was supposed to be a meal served, but there wasn’t and the major toilet was out of order

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

I selected first class expecting excetional service. It was mediocre at best. The food service was cold, meal choices was poor and on one leg they did provide dessert. I did enjoy the lay day seat but the movies were old and nothing current. Boarding the plane is always hot. So boarding is quite warm until your in the air. I took a small personal air fan. Update the meals and movies.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Seats not reclining, no vegetarian food option, no snacks. 7.5 hr flight should have been more comfortable. Luggage limits are unusually small. Will never fly Copa again and will tell friends and family to avoid this airline.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

Enforce the boarding process by group numbers. Tell people to stay seated during the meal/drink distribution. It took forever to get food and drinks because people would not stay out the isle and let the crew do their jobs. Everyone wanted to go to the bathroom forcing the crew to enter and leave the isle constantly so people can pass. Tell people to keep their electronics off speaker mode. No one wants to hear phone conversations and music playing.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

Excellent flight. Boarding was efficient and departure was on time. Smooth flight with on time arrival. Deplaning was also efficient.

It was delayed instead of departing at 9:20pm, we departed at 11pm… putting us in Columbus after 2am! It was awful. Had I known about the delay, I could have spent some time in the United Lounge… I was starving because I started my journey in Budapest… so I was exhausted and hungry. Plus I had to make new arrangements to be picked up at the airport in Columbus, instead of midnight it was 2:30 am after getting luggage and out of airport. Not feasible. I would have just stayed in Chicago for the night and gotten a morning flight.

It was great, I’m very grateful for the pilots and crew flight attendants for everything.

Evidently, my seat had the only broken TV. I couldn’t plug it in, get it to come on, or watch anything, and of course, no one could fix it while we were on the plane. The service was good and the boarding was quick

The boarding of took of late.The presentation of the food was horrable as was the tast of the food was cold and tastless.

Delay and keep changing gates. I have to run around from B to C then to E.

I was charged for my daughters bag when I am supposed to receive two free checked bags with my United Explorer card.

The schedule to Moline changed 5 times. The gate changed 6 times. That is a pathetic way to run an airline. No wonder that no one in our company flies on United Express to or from Moline. Changes happen most of the time. I learned my lesson on this trip…never again!

Flight was great. Efficient boarding. Short flight. Early arrival. Friendly flight crew. The entertainment system did not work well. Could not access it until the aircraft reached 10K feet or more. Lots of glitches.

A bit rush for transit. Food and entertainment are not available

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

After a two hour delay, my flight was CANCELLED! No pilot available. Such BS.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

I wish American Airlines would change the airline industry by loading the plane back to front instead of front to back. Planes would board so much more smoothly and quickly.

I have long legs, my foot was out in the aisle and when a flight attendant came walking by and I didn't notice, instead of saying "excuse me" or anything like that, she kicked my foot. Extremely rude

Excellent! The gate agents were kind enough to rebook me on an earlier flight saving me from a 6 hour layover. Even my luggage made it despite the fact that the connection was technically too narrow. The flight itself was very comfortable, roomy, and clean. Plenty of space for my carryon items with plugs to charge my phone. After a long international flight of 14 hours, this was an excellent way to end my travels!

Great experience. Flight boarded easily. Departed early. Smooth flight. Great arrival in DC--almost no taxing! Almost direct to gate from runway. Crew was terrific. Same cookies and beverages in main cabin. I did not use the entertainment system on this flight.

This particular flight wasn't very full at the back, so there were three seats available for spreading out and getting relatively comfortable

Most of the delay was due to weather which is not what was at issue here. One delay was due to a missing flashlight and in the end the flashlight was actually found on the plane. The entertainment system is very limited. Live TV options offer only a few channels that are not very appealing. Boarding and deplaning are always difficult. It just takes too much time to get on and off the plane. On the plus side, I missed my connecting flight, but was easily able to book a later flight from the app while enroute.

Very uncomfortable planes , poor service on the plane , take your own water so you don’t dehydrate , in a 6 hs flight they sold one time food and beverage . 1 plane was delayed 6 hs , I lost a connecting flight . Then in the way back they announce a delay of 2 hs so I had to take a different flight to arrive on time for my connecting flight . Avoid this airline .

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Seats are very tight even in Plus, no complimentary snacks or beverage

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

I receive a service for what I pay, so it is fair.

Excellent flight and one of the smoothest landing I’ve ever experienced

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

There isn't much space in-between seats and even water needs to be paid for during the flight.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Everything you need to know for your flight from Chicago to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

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