Find Cheap Flights from Chicago to Panama

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
Compare vs. KAYAK all | none
Browse Origins:
Browse Destinations:

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Chicago to Panama

(Round-trip)
Depart: Mon Aug 14 2017 Return: Thu Aug 24 2017 Trip spans 11 days
Major Airline
Major Airline
ORD
PTY
10h 27m
1 stop
PTY
ORD
11h 18m
1 stop
Depart: Mon Aug 21 2017 Return: Wed Oct 4 2017 Trip spans 45 days
Spirit Airlines
Spirit Airlines
ORD
PTY
8h 29m
1 stop
PTY
ORD
7h 50m
1 stop
Depart: Wed Jun 21 2017 Return: Tue Jun 27 2017 Trip spans 7 days
Avianca
Avianca
ORD
PTY
7h 30m
1 stop
PTY
ORD
50h 55m
2 stops
Depart: Wed May 24 2017 Return: Sat May 27 2017 Trip spans 4 days
Delta
Delta
MDW
PTY
11h 09m
1 stop
PTY
MDW
14h 04m
1 stop
Depart: Fri Sep 8 2017 Return: Wed Sep 20 2017 Trip spans 13 days
Aeromexico
Aeromexico
ORD
DAV
35h 46m
2 stops
DAV
ORD
37h 21m
2 stops
Depart: Wed Sep 6 2017 Return: Sat Sep 9 2017 Trip spans 4 days
Spirit Airlines
Spirit Airlines
ORD
PTY
8h 29m
1 stop
PTY
ORD
7h 50m
1 stop
Depart: Thu Oct 5 2017 Return: Sun Oct 8 2017 Trip spans 4 days
Major Airline
Major Airline
ORD
PTY
10h 27m
1 stop
PTY
ORD
10h 22m
1 stop
Depart: Tue Nov 7 2017 Return: Thu Nov 16 2017 Trip spans 10 days
Major Airline
Major Airline
ORD
PTY
21h 35m
2 stops
PTY
ORD
13h 55m
2 stops
Depart: Wed Jul 12 2017 Return: Wed Jul 19 2017 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
PTY
17h 39m
1 stop
PTY
ORD
8h 49m
1 stop
Depart: Mon Jul 31 2017 Return: Mon Aug 7 2017 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
PTY
17h 39m
1 stop
PTY
ORD
8h 49m
1 stop
Depart: Mon Jun 19 2017 Return: Thu Jun 22 2017 Trip spans 4 days
Major Airline
Major Airline
ORD
PTY
8h 19m
1 stop
PTY
ORD
12h 50m
1 stop
Depart: Sun Jul 16 2017 Return: Wed Jul 26 2017 Trip spans 11 days
Avianca
Avianca
ORD
PTY
7h 30m
1 stop
PTY
ORD
7h 40m
1 stop
Depart: Thu Jun 8 2017 Return: Thu Jun 22 2017 Trip spans 15 days
Delta
Delta
MDW
PTY
9h 25m
1 stop
PTY
MDW
9h 04m
1 stop
Depart: Wed Jun 21 2017 Return: Sun Jun 25 2017 Trip spans 5 days
Delta
Delta
MDW
PTY
7h 48m
1 stop
PTY
MDW
9h 04m
1 stop
Depart: Wed Jun 21 2017 Return: Sat Jun 24 2017 Trip spans 4 days
Major Airline
Major Airline
ORD
PTY
8h 54m
1 stop
PTY
ORD
10h 36m
1 stop
Depart: Sat Jul 29 2017 Return: Sat Aug 12 2017 Trip spans 15 days
Delta
Delta
MDW
PTY
14h 10m
1 stop
PTY
MDW
9h 04m
1 stop
Depart: Wed May 24 2017 Return: Fri May 26 2017 Trip spans 3 days
Major Airline
Major Airline
ORD
PTY
8h 13m
1 stop
PTY
ORD
7h 40m
1 stop
Depart: Mon Jul 31 2017 Return: Tue Aug 8 2017 Trip spans 9 days
Delta
Delta
MDW
PTY
9h 30m
1 stop
PTY
MDW
14h 37m
1 stop
Depart: Tue Jun 20 2017 Return: Mon Jun 26 2017 Trip spans 7 days
Aeromexico
Aeromexico
ORD
DAV
35h 48m
2 stops
DAV
ORD
42h 17m
2 stops
Depart: Wed May 24 2017 Return: Mon May 29 2017 Trip spans 6 days
Major Airline
Major Airline
ORD
PTY
22h 35m
1 stop
PTY
ORD
30h 40m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

Here's why:

We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

We compile tonnes of data for you
Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
please send us an email and someone from our team will get back to you promptly.

Airports
Origin

Chicago
only $452
only $624
Destination

Panama City
$452
David
$806