Find Cheap Flights from Chicago to Panama

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
Compare vs. KAYAK all | none
Browse Origins:
Browse Destinations:

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Chicago to Panama

(Round-trip)
Depart: Wed May 10 2017 Return: Mon May 15 2017 Trip spans 6 days
Spirit Airlines
Spirit Airlines
ORD
PTY
17h 42m
1 stop
PTY
ORD
8h 47m
1 stop
Depart: Sat Jul 1 2017 Return: Tue Jul 4 2017 Trip spans 4 days
Major Airline
Major Airline
ORD
PTY
9h 07m
1 stop
PTY
ORD
13h 46m
1 stop
Depart: Tue May 23 2017 Return: Tue May 30 2017 Trip spans 8 days
Aeromexico
Aeromexico
ORD
PTY
22h 35m
1 stop
PTY
ORD
21h 35m
1 stop
Depart: Thu Sep 7 2017 Return: Thu Sep 14 2017 Trip spans 8 days
Avianca
Avianca
ORD
PTY
7h 30m
1 stop
PTY
ORD
7h 40m
1 stop
Depart: Wed Apr 26 2017 Return: Mon May 8 2017 Trip spans 13 days
Delta
Delta
MDW
PTY
7h 22m
1 stop
PTY
MDW
10h 30m
1 stop
Depart: Mon Jun 5 2017 Return: Wed Jun 7 2017 Trip spans 3 days
Spirit Airlines
Spirit Airlines
ORD
PTY
8h 13m
1 stop
PTY
ORD
8h 45m
1 stop
Depart: Tue Aug 22 2017 Return: Thu Aug 31 2017 Trip spans 10 days
Major Airline
Major Airline
ORD
PTY
5h 18m
nonstop
PTY
ORD
5h 32m
nonstop
Depart: Sat May 13 2017 Return: Fri May 19 2017 Trip spans 7 days
Aeromexico
Aeromexico
ORD
PTY
30h 45m
1 stop
PTY
ORD
21h 38m
1 stop
Depart: Wed Oct 11 2017 Return: Wed Oct 18 2017 Trip spans 8 days
Major Airline
Major Airline
ORD
PTY
13h 04m
1 stop
PTY
ORD
7h 40m
1 stop
Depart: Wed Jun 21 2017 Return: Mon Jun 26 2017 Trip spans 6 days
Spirit Airlines
Spirit Airlines
ORD
PTY
17h 48m
1 stop
PTY
ORD
8h 46m
1 stop
Depart: Thu May 11 2017 Return: Sun May 21 2017 Trip spans 11 days
Delta
Delta
MDW
PTY
11h 09m
1 stop
PTY
MDW
10h 30m
1 stop
Depart: Tue May 23 2017 Return: Tue May 30 2017 Trip spans 8 days
Delta
Delta
MDW
PTY
11h 09m
1 stop
PTY
MDW
14h 05m
1 stop
Depart: Sat Jul 8 2017 Return: Fri Jul 14 2017 Trip spans 7 days
Major Airline
Major Airline
ORD
PTY
21h 25m
2 stops
PTY
ORD
32h 30m
2 stops
Depart: Sat May 27 2017 Return: Sat Jun 3 2017 Trip spans 8 days
Delta
Delta
MDW
PTY
14h 10m
1 stop
PTY
MDW
11h 43m
1 stop
Depart: Sun Jun 11 2017 Return: Sun Jun 18 2017 Trip spans 8 days
Delta
Delta
MDW
PTY
14h 10m
1 stop
PTY
MDW
12h 43m
1 stop
Depart: Tue Jun 13 2017 Return: Tue Jul 25 2017 Trip spans 43 days
Major Airline
Major Airline
ORD
PTY
5h 18m
nonstop
PTY
ORD
5h 32m
nonstop
Depart: Fri Jun 30 2017 Return: Tue Jul 4 2017 Trip spans 5 days
Delta
Delta
MDW
PTY
11h 20m
1 stop
PTY
MDW
9h 02m
1 stop
Depart: Thu Sep 28 2017 Return: Sun Oct 1 2017 Trip spans 4 days
Major Airline
Major Airline
ORD
PTY
5h 18m
nonstop
PTY
ORD
5h 32m
nonstop
Depart: Sat Jul 8 2017 Return: Sat Jul 15 2017 Trip spans 8 days
Delta
Delta
MDW
PTY
9h 30m
1 stop
PTY
MDW
14h 31m
1 stop
Depart: Fri Oct 20 2017 Return: Sat Oct 28 2017 Trip spans 9 days
Major Airline
Major Airline
ORD
PTY
5h 18m
nonstop
PTY
ORD
5h 32m
nonstop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

We attempt to get accurate prices, however, prices are not guaranteed.

Here's why:

We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

We compile tonnes of data for you
Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

If you have more questions or if you have a bad price to report to us,
please send us an email and someone from our team will get back to you promptly.

Airports
Origin

Chicago
only $452
only $624
Destination

Panama City
$452