$316 Find Cheap Flights from Chicago to Panama City - Compare and Save

If you are looking for a flight deal from Chicago to Panama City, look for departures on Wednesdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Panama City, Saturday is the cheapest day to fly and Monday is the most expensive.

The cheapest month for flights from Chicago O'Hare Intl Airport to Panama City is March, where tickets cost $594 (return) on average. On the other hand, the most expensive months are August and July, where the average cost of round-trip tickets is $823 and $750 respectively.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $857 on average.

To get a below average price on the flight from Chicago O'Hare Intl Airport to Panama City, you should book around 5 weeks before departure, which saves you about 29% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Weekly flights between Chicago and Panama City historically see delays in approximately 12% of cases, with the average delay over the past year being 120 minutes.

Typically, flights leaving in the morning tend to face fewer delays, whereas flights in the evening have historically encountered delays more often.

Statistically, Thursday is the day of the week with the fewest delays on this flight route, while Sunday has typically experienced more delays than other days.

Based on our data, Copa Airlines have experienced the fewest delays on this route in the past 12 months, with only about 12% of their flights encountering any delays.

Houston (IAH) is the top choice – 42% of KAYAK users who clicked on 1-stop flights from Chicago to Panama City picked an itinerary connecting there.

Flights via Bogotá (BOG) offer the most affordable fares, with an average round-trip price of $430.

Consider flying via Atlanta (ATL) for the shortest journey. The average one-way travel time for flights connecting there is 7h 25m.

If you prefer a quick connection, Houston (IAH) often has the shortest layovers from Chicago to Panama City, with an average of 1h 31m.

There are 3 cabin class options for the route. These are Business, Economy and Prem Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

Each day, there are between 1 and 2 nonstop flights that take off from Chicago O'Hare Intl Airport and land in Panama City, with an average flight time of 5h 21m. The most common departure time is 8:00 am and most flights take off in the morning. Each week, there are 12 flights. The most frequent day of departure is Monday, when 17% of all weekly flights depart. The fewest flights depart on a Tuesday.