$307 Find Cheap Flights from Chicago O'Hare Airport to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to Panama departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from O'Hare Intl to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City3 stops$663
David
David1 stop$812
Panama City
Panama City3 stops$663
David
David1 stop$812

Book Cheap O'Hare Intl to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to Panama

Mon, Aug 31 - Wed, Sep 30
Multiple Airlines Logo
1:40 am - 9:15 am
ORD
-
PTY
31h 35m
3 stops
Multiple Airlines Logo
5:30 am - 5:52 am
PTY
-
ORD
24h 22m
3 stops
$663Multiple Airlines
Thu, Sep 10 - Mon, Sep 14
Multiple Airlines Logo
1:40 am - 9:15 am
ORD
-
PTY
31h 35m
3 stops
Multiple Airlines Logo
5:30 am - 5:52 am
PTY
-
ORD
24h 22m
3 stops
$679Multiple Airlines
Mon, Sep 28 - Sun, Oct 4
Multiple Airlines Logo
1:40 am - 9:15 am
ORD
-
PTY
31h 35m
3 stops
Multiple Airlines Logo
7:24 am - 5:52 am
PTY
-
ORD
22h 28m
2 stops
$684Multiple Airlines
Thu, Sep 10 - Mon, Sep 14
Multiple Airlines Logo
1:40 am - 9:15 am
ORD
-
PTY
31h 35m
3 stops
Multiple Airlines Logo
5:30 am - 5:52 am
PTY
-
ORD
24h 22m
3 stops
$686Multiple Airlines
Wed, Jul 15 - Tue, Jul 21
Copa Airlines Logo
3:21 pm - 9:03 am
ORD
-
DAV
17h 42m
1 stop
Copa Airlines Logo
9:45 am - 4:00 am
DAV
-
ORD
18h 15m
1 stop
$812Copa Airlines
Sat, Jul 4 - Sat, Jul 11
Copa Airlines Logo
8:02 am - 9:03 am
ORD
-
DAV
25h 01m
1 stop
Copa Airlines Logo
7:54 pm - 1:57 pm
DAV
-
ORD
18h 03m
1 stop
$1,134Copa Airlines
Fri, Aug 28 - Sun, Aug 30
United Airlines Logo
5:00 am - 9:08 am
ORD
-
DAV
28h 08m
2 stops
United Airlines Logo
9:50 am - 10:15 am
DAV
-
ORD
24h 25m
2 stops
$1,195United Airlines
Sun, Aug 30 - Tue, Sep 1
United Airlines Logo
6:00 am - 9:08 am
ORD
-
DAV
27h 08m
2 stops
United Airlines Logo
9:50 am - 10:15 am
DAV
-
ORD
24h 25m
2 stops
$1,205United Airlines
Fri, Nov 6 - Fri, Nov 13
Copa Airlines Logo
9:00 am - 8:50 am
ORD
-
DAV
22h 50m
2 stops
Copa Airlines Logo
9:48 am - 12:15 am
DAV
-
ORD
15h 27m
2 stops
$1,241Copa Airlines
Sun, Jul 5 - Fri, Jul 17
Copa Airlines Logo
6:29 am - 9:03 am
ORD
-
DAV
26h 34m
2 stops
Copa Airlines Logo
9:45 am - 12:45 am
DAV
-
ORD
15h 00m
2 stops
$1,251Copa Airlines
Booking Insights

KAYAK's insights & trends for O'Hare Intl to Panama flights

Get data-powered insights and trends into flights from O'Hare Intl to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago O'Hare Intl Airport to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Chicago O'Hare Intl Airport found in the last 5 days was to Panama City, at $406 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 5 days was $406.

What is the cheapest time of day to fly to Panama?

The average price for all round-trip flights from Chicago O'Hare Intl Airport to Panama depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Panama is generally at night, when round-trip flights cost $475 on average. Morning departures are around 2% more expensive than evening flights, on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $584.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to Panama?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $736 on average.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to Panama is February, when tickets cost $102 (return) on average. On the other hand, the most expensive months are June and July, when the average cost of round-trip tickets is $536 and $464 respectively.

What’s the cheapest day of the week to fly from Chicago O'Hare Airport to Panama?

The average price of all round-trip flights from Chicago O'Hare Intl Airport to Panama clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Panama on a Tuesday and more expensive on a Saturday. On your return trip to Chicago O'Hare Airport, you should consider flying back on a Saturday, and avoid Sundays for better deals.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to Panama, you should book around 5 weeks before departure, which saves you about 29% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low seasonJune
Cheapest flight$307
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Chicago O'Hare Airport to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago O'Hare Airport to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago O'Hare Airport to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago O'Hare Airport to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from O'Hare Intl to Panama

 
Need help choosing which airline to fly with from O'Hare Intl to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1569 reviews
6.9Food
8.1Crew
7.4Comfort
6.8Entertainment
7.8Boarding
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

Horrible! Several delays and then was cancelled! I spent over 24 hours in the airport and was unable to get a hotel or food voucher.

Smooth travel. Immediate update prior flight delay so I can arrange myself properly without too rush.

Boarded early; and arrived home 40 mins early. After a long flight, it’s nice to be back home early. These flights have no amenities; no snacks. So need to bring your own

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Crew was friendly. Seats are too narrow, particularly when a big person is in the adjacent seat, but I understand this is due to smaller planes usually flight into Lincoln. I have experienced several flight delays going out and coming into Lincoln airport, I say maybe 50% or higher of the flights I've taken out of this airport have been delayed.

Great flight. Boarded efficiently. Arrived early at CLT. There was no in flight entertainment on this aircraft. Great crew.

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

Significant delays on my trip to Chicago and my trip back to NY

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

I’ve got 31F seat and window seat . My 2 co passengers was AA crew members and they were very rude attitude and when I was going to use bathroom their gestures was very different and awkward and the guy beside me completely occupied the hand rest and I was really uncomfortable

It was so much better than expected, Ohare is not such a pleasant experience but American Airlines with the new, clean aeroplane and free Wi-Fi was outstanding and the crew so pleasant and helpful.

It wa sort of on time; the cab was left with some trash

My pillow had a shoe print on it, when I asked if I can have another pillow, I was told “I’m sorry but it is one pillow per guest, do YOU want to turn it inside out” to which I responded , no thanks I will go without. This is generally not ok, but For the price tag I paid flying business this is absolutely unacceptable. Hopefully American Airlines can update their accommodations to bedding that is not tossed on the ground and stepped on, or at least have a couple of extra pillows in hand, incase someone had decided to step on the pillows for what ever reason

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Our flight was cancelled while we are on our way to the airport. So, no notice. We were rescheduled to another airline with a 2 hour later takeoff and so arrived at our destination on time. We pre-paid American Airlines $190 to upgrade our seats. No refund. So no use for AA or Kayak.

Terrible, horrible, disappointing- without telling us they changed planes and moved and separated our seats to opposite sides - said they changed seats putting us together - got to airport to find no, they did not - we sat opposing sides of plane - food overly salty to inedible, never saw stewardess but once - it was terrible

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

A flawless trip, great experience. Keep up the good work!

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

Overall, the flight went well and the service was good. However, there was a very frightening moment during landing in Bogotá. Just as the plane was about to touch down, it suddenly went back up into the air. The aircraft was not descending straight and seemed to move left and right, which made the situation feel unstable. This was quite scary. After going back up, the plane circled for about 15 minutes before attempting to land again. Although I understand that safety always comes first and situations like this can happen, it was still a shocking experience for passengers.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Everything you need to know for your flight from O'Hare Intl to Panama

Information on your arrival and departure airports