DSM - BRU

$579 Find Cheap Flights from Des Moines to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Brussels departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to Brussels (DSM-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Brussels

Tue, Sep 23 - Tue, Sep 30
United Airlines Logo
11:35 am - 8:05 amDSM-BRU
13h 30m2 stops
United Airlines Logo
10:00 am - 2:23 pmBRU-DSM
35h 23m2 stops
$723United Airlines
Find Deal
Tue, Sep 23 - Tue, Sep 30
 Logo
8:00 am - 8:05 amDSM-BRU
17h 05m2 stops
 Logo
10:00 am - 9:50 pmBRU-DSM
18h 50m3 stops
Tue, Sep 23 - Tue, Sep 30
 Logo
8:00 am - 8:05 amDSM-BRU
17h 05m2 stops
 Logo
10:00 am - 9:50 pmBRU-DSM
18h 50m3 stops
Tue, Sep 23 - Tue, Sep 30
 Logo
8:00 am - 8:05 amDSM-BRU
17h 05m3 stops
 Logo
10:00 am - 9:50 pmBRU-DSM
18h 50m3 stops
Tue, Sep 23 - Tue, Sep 30
United Airlines Logo
1:10 pm - 9:00 amDSM-BRU
12h 50m1 stop
United Airlines Logo
10:15 am - 5:24 pmBRU-DSM
14h 09m1 stop
$746United Airlines
Find Deal
Mon, Sep 29 - Mon, Oct 6
Scandinavian Airlines Logo
2:05 pm - 3:20 pmDSM-BRU
18h 15m2 stops
Scandinavian Airlines Logo
4:00 pm - 10:30 pmBRU-DSM
37h 30m2 stops
$755Scandinavian Airlines
Find Deal
Sun, Sep 28 - Sun, Oct 5
Air Canada Logo
6:36 pm - 8:05 amDSM-BRU
30h 29m2 stops
Air Canada Logo
10:00 am - 10:42 amBRU-DSM
31h 42m2 stops
$777Air Canada
Find Deal
Mon, Sep 29 - Mon, Oct 6
Air Canada Logo
8:00 am - 9:00 amDSM-BRU
18h 00m1 stop
Air Canada Logo
10:15 am - 5:24 pmBRU-DSM
14h 09m1 stop
$780Air Canada
Find Deal
Tue, Sep 23 - Tue, Sep 30
Lufthansa Logo
1:10 pm - 9:00 amDSM-BRU
12h 50m1 stop
Lufthansa Logo
10:15 am - 9:50 pmBRU-DSM
18h 35m1 stop
$946Lufthansa
Find Deal
Sun, Sep 28 - Sun, Oct 5
Lufthansa Logo
1:00 pm - 9:00 amDSM-BRU
13h 00m1 stop
Lufthansa Logo
10:15 am - 5:24 pmBRU-DSM
14h 09m1 stop
$980Lufthansa
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to Brussels flights

Get data-powered insights and trends into flights from Des Moines to Brussels to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to Brussels?

The average price of all round-trip flights from Des Moines to Brussels Bruxelles-National Airport clicked on KAYAK for each day over the last 12 months.

For Des Moines to Brussels, Wednesday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Brussels back to Des Moines, the best deals are generally found on Wednesday, with Friday being the most expensive.

Good to know

Cheapest flight$579
Flight from Des Moines to Brussels

When to book flights from Des Moines to Brussels

Are your dates flexible? Find out the best times to travel from Des Moines to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Des Moines to Brussels flights

  • What is the cheapest flight from Des Moines to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Des Moines to Brussels Bruxelles-National Airport was $579 for a one-way ticket and $723 for a round-trip.

  • Do I need a passport to fly between Des Moines and Brussels?

    Yes

  • Which aircraft models fly most regularly from Des Moines to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Brussels?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Des Moines and Brussels, with Star Alliance being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Des Moines to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8915 reviews
7.7Boarding
7.3Comfort
7.1Entertainment
6.6Food
8.1Crew
Airline reviews

Had to cancel first flight because Airporter Bus took over 3 hrs to get to airport which resulted in an extra $378 dollar fare . Is there anyway I can be reimbursed for initial fare since it was not my fault? Sent from my iPhone EJ Ledet

2.0 MediocreAnonymous, Aug 2025SEA - DEN
Read more United Airlines reviews

Had to cancel first flight because Airporter Bus took over 3 hrs to get to airport which resulted in an extra $378 dollar fare . Is there anyway I can be reimbursed for initial fare since it was not my fault? Sent from my iPhone EJ Ledet

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

The pilots were late and it made us 1 hour late. The meat was tough and bok choy was also tough.

Flight was delayed 3 hours. No food and drink vouchers was provided. They offered a mini pretzel bag and water .

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

The service was good, the food could have been better.

Staff was rude. Didn’t give water for 2 hours. Worst service

Excellent flight. Boarding was efficient and departure was on time. Smooth flight with on time arrival. Deplaning was also efficient.

This flight was perfect. No complaints and only the highest regard for the crew and ground staff and how they executed perfectly. I fly a lot with United and would request predictability and transparency in their operations instead of last minute changes.

Everything you need to know for your flight from Des Moines to Brussels

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