DSM - BRU

$357 Find Cheap Flights from Des Moines to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Brussels departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$518
Air Canada
Tue 3/24Tue 3/31
DSM - BRU • 2 stops
Cheapest one-way
$357
Aer Lingus
Sat 5/2
DSM - BRU • 2 stops
Top airlines
Air Canada
Cheapest • from $518 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Brussels (DSM-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Brussels

Tue, Mar 24 - Tue, Mar 31
Air Canada Logo
8:00 am - 7:50 am
DSM
-
BRU
17h 50m
2 stops
Air Canada Logo
9:25 am - 10:59 pm
BRU
-
DSM
20h 34m
2 stops
$518Air Canada
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
8:00 am - 1:15 pm
DSM
-
BRU
23h 15m
2 stops
United Airlines Logo
9:25 am - 2:25 pm
BRU
-
DSM
36h 00m
2 stops
$535United Airlines
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
8:00 am - 7:50 am
DSM
-
BRU
17h 50m
3 stops
Multiple Airlines Logo
9:40 am - 9:27 pm
BRU
-
DSM
18h 47m
2 stops
$543Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
Air Canada Logo
8:00 am - 7:50 am
DSM
-
BRU
17h 50m
2 stops
Air Canada Logo
9:25 am - 10:59 pm
BRU
-
DSM
20h 34m
2 stops
$548Air Canada
Tue, Mar 24 - Tue, Mar 31
Air Canada Logo
8:00 am - 7:50 am
DSM
-
BRU
17h 50m
2 stops
Air Canada Logo
9:25 am - 10:59 pm
BRU
-
DSM
20h 34m
2 stops
$556Air Canada
Tue, Mar 24 - Tue, Mar 31
Air Canada Logo
9:00 am - 7:50 am
DSM
-
BRU
16h 50m
2 stops
Air Canada Logo
9:25 am - 10:59 pm
BRU
-
DSM
20h 34m
2 stops
$557Air Canada
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
5:30 am - 7:50 am
DSM
-
BRU
20h 20m
2 stops
Multiple Airlines Logo
10:15 am - 10:59 pm
BRU
-
DSM
19h 44m
1 stop
$559Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
United Airlines Logo
11:26 am - 7:50 am
DSM
-
BRU
14h 24m
2 stops
United Airlines Logo
10:15 am - 10:59 pm
BRU
-
DSM
19h 44m
1 stop
$562United Airlines
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
8:00 am - 7:50 am
DSM
-
BRU
17h 50m
3 stops
Multiple Airlines Logo
9:40 am - 9:27 pm
BRU
-
DSM
18h 47m
2 stops
$570Multiple Airlines
Tue, Mar 24 - Tue, Mar 31
Multiple Airlines Logo
8:00 am - 7:50 am
DSM
-
BRU
17h 50m
3 stops
Multiple Airlines Logo
9:40 am - 9:27 pm
BRU
-
DSM
18h 47m
2 stops
$571Multiple Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Brussels flights

Get data-powered insights and trends into flights from Des Moines to Brussels to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Brussels were found on Air Canada ($518) and United Airlines ($535).

Find deals

Good to know

Cheapest flight$357
Flight from Des Moines to Brussels

When to book flights from Des Moines to Brussels

Are your dates flexible? Find out the best times to travel from Des Moines to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Des Moines to Brussels flights

  • What is the cheapest flight from Des Moines to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Des Moines to Brussels Bruxelles-National Airport was $357 for a one-way ticket and $518 for a round-trip.

  • Do I need a passport to fly between Des Moines and Brussels?

    Yes

  • Which aircraft models fly most regularly from Des Moines to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Brussels?

    Star Alliance is the only airline alliance operating flights between Des Moines and Brussels.

  • How does KAYAK find such low prices on flights from Des Moines to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9289 reviews
7.3Comfort
7.1Entertainment
6.6Food
7.7Boarding
8.1Crew
Airline reviews

Both the WIFI and entertainment did not work for 2.5h

6.0 GoodAnonymous, Feb 2026
HNL - NRT
Read more United Airlines reviews

Both the WIFI and entertainment did not work for 2.5h

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

Very old flight - time to retire it for newer airplanes

2+ hours delayed Outlet in row 12 did not work Tv monitors did not work Lights kept off the entire flight for at 5pm-7pm flight

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Everything you need to know for your flight from Des Moines to Brussels

Information on your arrival and departure airports

Des Moines (DSM)
Bruxelles-National (BRU)