DSM - BRU

$262 Find Cheap Flights from Des Moines to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Brussels departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$458
British Airways
Mon 4/20Mon 4/27
DSM - BRU • 2 stops
Cheapest one-way
$262
KLM
Sat 5/2
DSM - BRU • 1 stop
Top airlines
British Airways
Cheapest • from $458 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Brussels (DSM-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Brussels

Mon, Apr 20 - Mon, Apr 27
British Airways Logo
2:18 pm - 2:25 pm
DSM
-
BRU
17h 07m
2 stops
British Airways Logo
8:50 pm - 7:31 pm
BRU
-
DSM
29h 41m
2 stops
$458British Airways
Fri, Feb 27 - Fri, Mar 6
British Airways Logo
1:38 pm - 5:20 pm
DSM
-
BRU
20h 42m
2 stops
British Airways Logo
9:50 am - 10:20 pm
BRU
-
DSM
19h 30m
2 stops
$472British Airways
Fri, Feb 27 - Fri, Mar 6
United Airlines Logo
8:00 am - 1:15 pm
DSM
-
BRU
22h 15m
2 stops
United Airlines Logo
10:00 am - 2:32 pm
BRU
-
DSM
35h 32m
2 stops
$485United Airlines
Sun, Mar 1 - Sun, Mar 8
Finnair Logo
11:17 am - 10:30 pm
DSM
-
BRU
28h 13m
2 stops
Finnair Logo
7:10 pm - 11:42 pm
BRU
-
DSM
34h 32m
2 stops
$492Finnair
Fri, Feb 27 - Fri, Mar 6
British Airways Logo
1:38 pm - 3:25 pm
DSM
-
BRU
18h 47m
2 stops
British Airways Logo
11:45 am - 11:40 pm
BRU
-
DSM
18h 55m
2 stops
$494British Airways
Sat, Feb 21 - Sat, Feb 28
United Airlines Logo
3:24 pm - 8:55 am
DSM
-
BRU
10h 31m
1 stop
United Airlines Logo
10:10 am - 8:07 pm
BRU
-
DSM
16h 57m
2 stops
$500United Airlines
Fri, Feb 27 - Fri, Mar 6
British Airways Logo
1:38 pm - 3:25 pm
DSM
-
BRU
18h 47m
2 stops
British Airways Logo
9:50 am - 10:20 pm
BRU
-
DSM
19h 30m
2 stops
$503British Airways
Fri, Feb 27 - Fri, Mar 6
United Airlines Logo
8:00 am - 1:15 pm
DSM
-
BRU
22h 15m
2 stops
United Airlines Logo
10:10 am - 9:40 pm
BRU
-
DSM
18h 30m
1 stop
$505United Airlines
Sat, Feb 28 - Sat, Mar 7
United Airlines Logo
9:04 am - 1:15 pm
DSM
-
BRU
21h 11m
2 stops
United Airlines Logo
10:00 am - 9:30 am
BRU
-
DSM
30h 30m
2 stops
$508United Airlines
Sat, Feb 21 - Sat, Feb 28
British Airways Logo
7:44 pm - 4:40 pm
DSM
-
BRU
37h 56m
2 stops
British Airways Logo
7:25 pm - 11:40 pm
BRU
-
DSM
35h 15m
2 stops
$509British Airways
Booking Insights

KAYAK's insights & trends for Des Moines to Brussels flights

Get data-powered insights and trends into flights from Des Moines to Brussels to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Brussels were found on British Airways ($458) and United Airlines ($485).

Which airlines fly non-stop between Des Moines and Brussels Bruxelles-National Airport?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to Brussels Bruxelles-National Airport.

There is just one airline that flies from Des Moines to Brussels Bruxelles-National Airport direct and that is United Airlines. The best round-trip deal found from United Airlines for the route is $707.

Find deals

Good to know

Cheapest flight$262
Flight from Des Moines to Brussels

When to book flights from Des Moines to Brussels

Are your dates flexible? Find out the best times to travel from Des Moines to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Des Moines to Brussels flights

  • What is the cheapest flight from Des Moines to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Des Moines to Brussels Bruxelles-National Airport was $262 for a one-way ticket and $458 for a round-trip.

  • Do I need a passport to fly between Des Moines and Brussels?

    Yes

  • Which aircraft models fly most regularly from Des Moines to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Brussels?

    Star Alliance is the only airline alliance operating flights between Des Moines and Brussels.

  • How does KAYAK find such low prices on flights from Des Moines to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9163 reviews
7.1Entertainment
7.7Boarding
7.3Comfort
8.1Crew
6.6Food
Airline reviews

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

10.0 ExcellentDavid, Jan 2026
IAD - BNA
Read more United Airlines reviews

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Ineffective communication with United resulted in lost baggage. Their Baggage Tracing counter at MUC was shut down from 11:00-14:15 on my arrival. Undertrained, underinformed staff had me Running all over MUC to find someone to help me to no avail. Staff was rude, unhelpful, and unable to effectively use the systems they did have operational. They refused to contact United in any way or provide any accommodation or other resources while I waited for my luggage. This has destroyed my downstream itinerary. If they had even the slightest visibility I may have been able to reschedule/plan, but again, their staff provided nothing, and did nothing more than their website, which doesn’t even work on a standard phone browser. Miserable failure at all levels that weren’t associated with the operation of the aircraft.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

Everything you need to know for your flight from Des Moines to Brussels

Information on your arrival and departure airports

Des Moines (DSM)
Bruxelles-National (BRU)