DSM - BRU

$372 Find Cheap Flights from Des Moines to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Brussels departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$688
Air France, KLM
Wed 4/22Wed 4/29
DSM - BRU • 1 stop
Cheapest one-way
$360
Multiple Airlines
Sun 4/26
DSM - BRU • 3 stops
Top airlines
Air Canada
Cheapest • from $691 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Brussels. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $935 (round-trip)
Chicago (ORD)
Shortest trip • 13h 00m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Brussels (DSM-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Brussels

Wed, Apr 22 - Wed, Apr 29
Multiple Airlines Logo
11:51 am - 7:40 am
DSM
-
BRU
12h 49m
1 stop
Multiple Airlines Logo
8:05 am - 5:02 pm
BRU
-
DSM
15h 57m
2 stops
$688Multiple Airlines
Tue, Apr 28 - Tue, May 5
Air Canada Logo
7:16 pm - 7:50 am
DSM
-
BRU
29h 34m
2 stops
Air Canada Logo
9:55 am - 9:23 pm
BRU
-
DSM
18h 28m
2 stops
$691Air Canada
Wed, Apr 29 - Wed, May 6
Air Canada Logo
6:20 am - 7:50 am
DSM
-
BRU
18h 30m
2 stops
Air Canada Logo
9:55 am - 11:24 pm
BRU
-
DSM
20h 29m
2 stops
$693Air Canada
Tue, Apr 28 - Tue, May 5
Air Canada Logo
7:16 pm - 7:50 am
DSM
-
BRU
29h 34m
2 stops
Air Canada Logo
9:55 am - 9:23 pm
BRU
-
DSM
18h 28m
2 stops
$696Air Canada
Tue, Apr 28 - Tue, May 5
Multiple Airlines Logo
1:10 pm - 9:00 am
DSM
-
BRU
12h 50m
1 stop
Multiple Airlines Logo
9:55 am - 9:23 pm
BRU
-
DSM
18h 28m
2 stops
$698Multiple Airlines
Wed, Apr 29 - Wed, May 6
United Airlines Logo
11:28 am - 8:00 pm
DSM
-
BRU
25h 32m
2 stops
United Airlines Logo
9:55 am - 10:37 am
BRU
-
DSM
31h 42m
2 stops
$701United Airlines
Tue, Apr 28 - Tue, May 5
KLM Logo
2:44 pm - 7:40 am
DSM
-
BRU
33h 56m
1 stop
KLM Logo
9:45 am - 10:34 pm
BRU
-
DSM
19h 49m
1 stop
$703KLM
Tue, Apr 28 - Tue, May 5
United Airlines Logo
11:25 am - 9:00 am
DSM
-
BRU
14h 35m
1 stop
United Airlines Logo
9:55 am - 10:37 am
BRU
-
DSM
31h 42m
2 stops
$704United Airlines
Tue, Apr 28 - Tue, May 5
Lufthansa Logo
3:21 pm - 1:15 pm
DSM
-
BRU
14h 54m
2 stops
Lufthansa Logo
10:15 am - 9:23 pm
BRU
-
DSM
18h 08m
1 stop
$707Lufthansa
Wed, Apr 29 - Wed, May 6
Lufthansa Logo
8:04 am - 9:00 am
DSM
-
BRU
17h 56m
1 stop
Lufthansa Logo
10:15 am - 6:05 pm
BRU
-
DSM
14h 50m
1 stop
$711Lufthansa
Booking Insights

KAYAK's insights & trends for Des Moines to Brussels flights

Get data-powered insights and trends into flights from Des Moines to Brussels to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Brussels were found on Air Canada ($691) and United Airlines ($701).

Find deals

Good to know

Cheapest flight$360
Flight from Des Moines to Brussels

When to book flights from Des Moines to Brussels

Are your dates flexible? Find out the best times to travel from Des Moines to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Des Moines to Brussels flights

  • What is the cheapest flight from Des Moines to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Des Moines to Brussels Bruxelles-National Airport was $360 for a one-way ticket and $688 for a round-trip.

  • Do I need a passport to fly between Des Moines and Brussels?

    Yes

  • Which aircraft models fly most regularly from Des Moines to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Brussels?

    Star Alliance is the only airline alliance operating flights between Des Moines and Brussels.

  • How does KAYAK find such low prices on flights from Des Moines to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9431 reviews
7.7Boarding
7.1Entertainment
6.6Food
8.1Crew
7.3Comfort
Airline reviews

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

10.0 ExcellentAnonymous, Mar 2026
TPA - IAD
Read more United Airlines reviews

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

It’s always a great time flying with united airlines.

Everything you need to know for your flight from Des Moines to Brussels

Information on your arrival and departure airports

Des Moines (DSM)
Bruxelles-National (BRU)