DSM - BRU

$364 Find Cheap Flights from Des Moines to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Brussels departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Brussels, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$431
Air Canada
Thu 1/15Thu 1/22
DSM - BRU • 2 stops
Cheapest one-way
$364
Lufthansa
Sat 5/2
DSM - BRU • 1 stop
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We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Brussels (DSM-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Brussels

Thu, Jan 15 - Thu, Jan 22
Air Canada Logo
6:48 pm - 7:50 amDSM-BRU
30h 02m2 stops
Air Canada Logo
10:00 am - 9:50 pmBRU-DSM
18h 50m2 stops
$431Air Canada
Find Deal
Mon, Jan 12 - Mon, Jan 19
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
10:30 am - 9:50 pmBRU-DSM
18h 20m2 stops
$445Lufthansa
Find Deal
Tue, Jan 13 - Tue, Jan 20
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
10:30 am - 9:50 pmBRU-DSM
18h 20m2 stops
$446Lufthansa
Find Deal
Tue, Jan 13 - Tue, Jan 20
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
10:30 am - 9:50 pmBRU-DSM
18h 20m2 stops
$447Lufthansa
Find Deal
Wed, Jan 14 - Wed, Jan 21
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
9:00 am - 9:50 pmBRU-DSM
19h 50m2 stops
$448Lufthansa
Find Deal
Wed, Jan 14 - Wed, Jan 21
Lufthansa Logo
6:48 pm - 5:15 pmDSM-BRU
15h 27m2 stops
Lufthansa Logo
10:10 am - 5:47 pmBRU-DSM
14h 37m1 stop
$450Lufthansa
Find Deal
Wed, Jan 14 - Wed, Jan 21
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
9:00 am - 9:50 pmBRU-DSM
19h 50m2 stops
$451Lufthansa
Find Deal
Tue, Jan 13 - Tue, Jan 20
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
10:30 am - 9:50 pmBRU-DSM
18h 20m2 stops
$454Lufthansa
Find Deal
Wed, Jan 14 - Wed, Jan 21
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
10:10 am - 9:50 pmBRU-DSM
18h 40m1 stop
$455Lufthansa
Find Deal
Wed, Jan 14 - Wed, Jan 21
Lufthansa Logo
11:30 am - 8:55 amDSM-BRU
14h 25m1 stop
Lufthansa Logo
10:10 am - 5:47 pmBRU-DSM
14h 37m1 stop
$456Lufthansa
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to Brussels flights

Get data-powered insights and trends into flights from Des Moines to Brussels to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Des Moines to Brussels?

The average price of all round-trip flights from Des Moines to Brussels Bruxelles-National Airport clicked on KAYAK for each day over the last 12 months.

For Des Moines to Brussels, Wednesday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Brussels back to Des Moines, the best deals are generally found on Wednesday, with Friday being the most expensive.

Good to know

Cheapest flight$364
Flight from Des Moines to Brussels

When to book flights from Des Moines to Brussels

Are your dates flexible? Find out the best times to travel from Des Moines to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Des Moines to Brussels flights

  • What is the cheapest flight from Des Moines to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Des Moines to Brussels Bruxelles-National Airport was $364 for a one-way ticket and $431 for a round-trip.

  • Do I need a passport to fly between Des Moines and Brussels?

    Yes

  • Which aircraft models fly most regularly from Des Moines to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Brussels?

    Star Alliance is the only airline alliance operating flights between Des Moines and Brussels.

  • How does KAYAK find such low prices on flights from Des Moines to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9065 reviews
7.1Entertainment
8.1Crew
7.7Boarding
7.3Comfort
6.6Food
Airline reviews

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

8.0 Excellentt, Dec 2025ORD - RSW
Read more United Airlines reviews

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very bad! They kept delaying my flight and wouldn’t do anything about it

They brought an empty plane to the gate. Then a flight delay was announced for maintenance and waiting on a part. I was then put on a flight to San Francisco instead with a connecting flight to my final destination. Arrived at my final destination 2 hours late.

The only downside was my cell phone charger wouldn’t work in the charging port but everyone else’s would work in them all. My cell phone cable works fine in my hotel room in Frankfurt.

Flight and crew were great. United didn't inform crew of immigration process which was disappointing!

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Ot was overall fine. Left on time and had basic snacks. Weather was finicky but that’s not the airlines fault.

from SFO-> FRA flight, AVML meal was significantly less compared to regular meal, especially no Desert, no Bread, no sides.

Very nice flight love the small aircraft. We had a wonderful flight attendant. Nice to see someone that really enjoys her job. Don't have her name but had a southern accent.

Everything you need to know for your flight from Des Moines to Brussels

Information on your arrival and departure airports