Find Deals on Flights from Des Moines to Cayman Islands

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Cayman Islands

(Round-trip)
Depart: Sat Jun 10 2017 Return: Sun Jun 11 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
11:20a
GCM
7:15a
19h 55m
2 stops
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Tue May 2 2017 Return: Tue May 9 2017 Trip spans 8 days
Major Airline
Major Airline
DSM
1:00a
GCM
4:23a
3h 23m
1 stop
GCM
1:00a
DSM
4:23a
3h 23m
1 stop
Depart: Sat Jun 3 2017 Return: Sat Jun 10 2017 Trip spans 8 days
Delta
Delta
DSM
1:58a
GCM
10:14a
8h 16m
1 stop
GCM
9:35a
DSM
6:12p
8h 37m
1 stop
Depart: Sat Apr 8 2017 Return: Sat Apr 22 2017 Trip spans 15 days
United
United
DSM
2:40p
GCM
11:45a
21h 05m
2 stops
GCM
12:50p
DSM
3:14p
26h 24m
2 stops
Depart: Sun Jun 4 2017 Return: Sun Jun 11 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Fri Jul 7 2017 Return: Tue Jul 11 2017 Trip spans 5 days
Delta
Delta
DSM
2:00a
GCM
8:31a
6h 31m
1 stop
GCM
9:35a
DSM
6:07p
8h 32m
1 stop
Depart: Sat Aug 12 2017 Return: Sat Aug 26 2017 Trip spans 15 days
Major Airline
Major Airline
DSM
6:55a
GCM
9:00a
26h 05m
1 stop
GCM
8:45a
DSM
1:35p
28h 50m
1 stop
Depart: Tue Jun 6 2017 Return: Sun Jun 11 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Thu May 18 2017 Return: Fri May 26 2017 Trip spans 9 days
Delta
Delta
DSM
12:50p
GCM
8:31a
19h 41m
1 stop
GCM
9:35a
DSM
6:13p
8h 38m
1 stop
Depart: Sun Jul 9 2017 Return: Thu Jul 13 2017 Trip spans 5 days
Major Airline
Major Airline
DSM
12:09a
GCM
9:00a
8h 51m
1 stop
GCM
8:40a
DSM
10:00a
25h 20m
1 stop
Depart: Wed Jun 7 2017 Return: Sun Jun 11 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Thu Jul 6 2017 Return: Tue Jul 11 2017 Trip spans 6 days
Delta
Delta
DSM
12:50p
GCM
8:31a
19h 41m
1 stop
GCM
9:35a
DSM
6:07p
8h 32m
1 stop
Depart: Sat Mar 11 2017 Return: Mon Mar 13 2017 Trip spans 2 days
United
United
DSM
1:30p
GCM
7:56a
17h 26m
2 stops
GCM
12:55p
DSM
6:33a
17h 38m
2 stops
Depart: Thu Jun 8 2017 Return: Sun Jun 11 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Fri Jun 9 2017 Return: Sun Jun 11 2017 Trip spans 3 days
American Airlines
American Airlines
DSM
1:50a
GCM
10:10a
8h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Mon Jun 5 2017 Return: Sun Jun 11 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
11:20a
GCM
9:20a
22h 00m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Sat Jul 8 2017 Return: Wed Jul 12 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:31p
GCM
9:20a
17h 49m
2 stops
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Tue Jul 11 2017 Return: Sun Jul 16 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:00a
GCM
7:15a
28h 15m
2 stops
GCM
10:16a
DSM
9:01a
22h 45m
2 stops
Depart: Wed Jul 12 2017 Return: Sun Jul 16 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
7:15a
28h 15m
2 stops
GCM
10:16a
DSM
9:01a
22h 45m
2 stops
Depart: Mon Jul 10 2017 Return: Sun Jul 16 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
11:20a
GCM
9:20a
22h 00m
1 stop
GCM
10:16a
DSM
9:01a
22h 45m
2 stops
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$636
Destination

George Town
$636