Find Cheap Flights from Des Moines to Cayman Islands

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Cayman Islands

(Round-trip)
Depart: Tue Oct 10 2017 Return: Sun Oct 15 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
1:50a
GCM
4:01p
14h 11m
2 stops
GCM
11:19a
DSM
6:22p
7h 03m
1 stop
Depart: Sat Jul 8 2017 Return: Fri Jul 14 2017 Trip spans 7 days
Delta
Delta
DSM
2:00a
GCM
2:04p
12h 04m
1 stop
GCM
9:35a
DSM
6:07p
8h 32m
1 stop
Depart: Thu May 18 2017 Return: Tue May 23 2017 Trip spans 6 days
United
United
DSM
1:30a
GCM
11:50a
10h 20m
1 stop
GCM
12:37p
DSM
7:39p
7h 02m
1 stop
Depart: Mon May 22 2017 Return: Tue May 23 2017 Trip spans 2 days
American Airlines
American Airlines
DSM
1:59a
GCM
4:01p
14h 02m
2 stops
GCM
3:00a
DSM
5:16p
14h 16m
2 stops
Depart: Sun May 21 2017 Return: Thu May 25 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:44a
6h 44m
1 stop
GCM
8:05a
DSM
8:57a
24h 52m
2 stops
Depart: Wed May 24 2017 Return: Tue May 30 2017 Trip spans 7 days
$1291
Select
Major Airline
Major Airline
DSM
11:40p
GCM
9:50a
10h 10m
1 stop
GCM
8:37a
DSM
3:39p
7h 02m
1 stop
Depart: Mon May 29 2017 Return: Sun Jun 4 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:44a
6h 44m
1 stop
GCM
3:00a
DSM
6:16p
15h 16m
2 stops
Depart: Tue May 16 2017 Return: Tue May 23 2017 Trip spans 8 days
Delta
Delta
DSM
1:45a
GCM
8:35a
6h 50m
1 stop
GCM
9:35a
DSM
7:00p
9h 25m
1 stop
Depart: Mon Jun 12 2017 Return: Tue Jun 20 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
12:05p
GCM
7:12a
19h 07m
2 stops
GCM
10:53a
DSM
7:31a
20h 38m
2 stops
Depart: Wed May 17 2017 Return: Tue May 23 2017 Trip spans 7 days
Delta
Delta
DSM
1:45a
GCM
8:35a
6h 50m
1 stop
GCM
9:35a
DSM
7:00p
9h 25m
1 stop
Depart: Fri May 19 2017 Return: Tue May 23 2017 Trip spans 5 days
Delta
Delta
DSM
1:45a
GCM
8:35a
6h 50m
1 stop
GCM
9:35a
DSM
7:00p
9h 25m
1 stop
Depart: Fri Jul 7 2017 Return: Mon Jul 17 2017 Trip spans 11 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Sat May 20 2017 Return: Tue May 23 2017 Trip spans 4 days
Delta
Delta
DSM
1:45a
GCM
8:35a
6h 50m
1 stop
GCM
9:35a
DSM
7:00p
9h 25m
1 stop
Depart: Sun Jul 9 2017 Return: Mon Jul 17 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Mon Jul 10 2017 Return: Mon Jul 17 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Tue Jul 11 2017 Return: Mon Jul 17 2017 Trip spans 7 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Wed Jul 12 2017 Return: Mon Jul 17 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Thu Jul 13 2017 Return: Mon Jul 17 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Sat Aug 12 2017 Return: Sat Aug 26 2017 Trip spans 15 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:19a
DSM
6:22p
7h 03m
1 stop
Depart: Sat Sep 23 2017 Return: Sat Sep 30 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
11:19a
DSM
6:22p
7h 03m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$527
Destination

George Town
$527