Find Deals on Flights from Des Moines to Cayman Islands

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Book cheap flights from Des Moines to Cayman Islands

(Round-trip)
Depart: Tue Apr 25 2017 Return: Sun Apr 30 2017 Trip spans 6 days
Major Airline
Major Airline
DSM
10:40a
GCM
9:00a
22h 20m
2 stops
GCM
8:45a
DSM
9:25a
24h 40m
2 stops
Depart: Thu Aug 3 2017 Return: Thu Aug 10 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Sat Aug 12 2017 Return: Sat Aug 26 2017 Trip spans 15 days
Delta
Delta
DSM
2:00a
GCM
8:31a
6h 31m
1 stop
GCM
9:35a
DSM
6:05p
8h 30m
1 stop
Depart: Sat Jun 3 2017 Return: Tue Jun 6 2017 Trip spans 4 days
United
United
DSM
1:18a
GCM
10:35a
9h 17m
1 stop
GCM
12:37p
DSM
7:39p
7h 02m
1 stop
Depart: Sun Aug 6 2017 Return: Thu Aug 10 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Mon Aug 7 2017 Return: Thu Aug 10 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:20a
6h 20m
1 stop
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Sat Jul 29 2017 Return: Sat Aug 5 2017 Trip spans 8 days
Major Airline
Major Airline
DSM
6:55a
GCM
9:00a
26h 05m
1 stop
GCM
11:45p
DSM
12:47p
13h 02m
1 stop
Depart: Sat Jun 17 2017 Return: Thu Jun 22 2017 Trip spans 6 days
Delta
Delta
DSM
7:45a
GCM
2:04p
6h 19m
1 stop
GCM
9:35a
DSM
6:07p
8h 32m
1 stop
Depart: Sat Aug 5 2017 Return: Thu Aug 10 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:31p
GCM
9:20a
17h 49m
2 stops
GCM
10:30a
DSM
5:14p
6h 44m
1 stop
Depart: Sat Jul 22 2017 Return: Sun Jul 30 2017 Trip spans 9 days
Major Airline
Major Airline
DSM
6:55a
GCM
9:00a
26h 05m
1 stop
GCM
8:40a
DSM
3:40p
7h 00m
1 stop
Depart: Fri Aug 4 2017 Return: Fri Aug 11 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
9:37a
GCM
7:15a
21h 38m
2 stops
GCM
10:30a
DSM
4:33a
18h 03m
2 stops
Depart: Mon May 8 2017 Return: Sat May 13 2017 Trip spans 6 days
United
United
DSM
1:30a
GCM
11:50a
10h 20m
1 stop
GCM
8:45a
DSM
7:39p
10h 54m
1 stop
Depart: Thu Apr 27 2017 Return: Sun Apr 30 2017 Trip spans 4 days
American Airlines
American Airlines
DSM
1:50a
GCM
4:01p
14h 11m
2 stops
GCM
10:36a
DSM
5:16p
6h 40m
1 stop
Depart: Wed May 31 2017 Return: Sat Jun 10 2017 Trip spans 11 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:44a
6h 44m
1 stop
GCM
8:42a
DSM
5:09p
8h 27m
1 stop
Depart: Fri Jun 2 2017 Return: Sat Jun 10 2017 Trip spans 9 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
8:42a
DSM
5:09p
8h 27m
1 stop
Depart: Sun Jun 4 2017 Return: Sun Jun 11 2017 Trip spans 8 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Tue Jun 6 2017 Return: Sun Jun 11 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Wed Jun 7 2017 Return: Sun Jun 11 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Wed Jun 14 2017 Return: Mon Jun 19 2017 Trip spans 6 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
Depart: Thu Jun 15 2017 Return: Mon Jun 19 2017 Trip spans 5 days
American Airlines
American Airlines
DSM
3:00a
GCM
9:41a
6h 41m
1 stop
GCM
11:20a
DSM
6:16p
6h 56m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Des Moines
$544
Destination

George Town
$544