$576 Find Cheap Flights from Des Moines to the Cayman Islands

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Cayman Islands departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Des Moines to the Cayman Islands

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
George Town
George Town1 stop$576
George Town
George Town1 stop$576

Book Cheap Des Moines to the Cayman Islands Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Cayman Islands that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Cayman Islands

Wed, Jan 28 - Fri, Feb 6
American Airlines Logo
6:58 am - 2:00 pmDSM-GCM
6h 02m1 stop
American Airlines Logo
2:00 pm - 9:57 pmGCM-DSM
8h 57m1 stop
$576American Airlines
Find Deal
Wed, Jan 28 - Fri, Feb 6
American Airlines Logo
6:58 am - 7:51 pmDSM-GCM
11h 53m1 stop
American Airlines Logo
8:30 am - 11:01 pmGCM-DSM
15h 31m2 stops
$580American Airlines
Find Deal
Fri, Jan 2 - Thu, Jan 8
Delta Logo
5:50 am - 12:30 pmDSM-GCM
5h 40m1 stop
Delta Logo
2:00 pm - 10:28 pmGCM-DSM
9h 28m1 stop
$601Delta
Find Deal
Fri, Jan 2 - Thu, Jan 8
American Airlines Logo
5:49 am - 4:00 pmDSM-GCM
9h 11m2 stops
American Airlines Logo
2:15 pm - 8:58 amGCM-DSM
19h 43m2 stops
$605American Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
United Airlines Logo
9:44 pm - 4:30 pmDSM-GCM
17h 46m2 stops
United Airlines Logo
2:50 pm - 9:37 pmGCM-DSM
7h 47m1 stop
$626United Airlines
Find Deal
Fri, Jan 9 - Sat, Jan 17
American Airlines Logo
5:55 am - 7:51 pmDSM-GCM
12h 56m2 stops
American Airlines Logo
2:15 pm - 8:58 amGCM-DSM
19h 43m2 stops
$630American Airlines
Find Deal
Mon, Sep 15 - Mon, Sep 22
Delta Logo
5:44 am - 11:36 amDSM-GCM
5h 52m1 stop
Delta Logo
12:52 pm - 10:37 pmGCM-DSM
9h 45m1 stop
$635Delta
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
3:46 pm - 11:22 amDSM-GCM
19h 36m2 stops
American Airlines Logo
12:25 pm - 9:58 pmGCM-DSM
9h 33m2 stops
$639American Airlines
Find Deal
Sat, Sep 13 - Sat, Sep 20
American Airlines Logo
8:00 am - 11:22 amDSM-GCM
27h 22m1 stop
American Airlines Logo
12:25 pm - 11:06 pmGCM-DSM
10h 41m1 stop
$647American Airlines
Find Deal
Sat, Dec 27 - Sat, Jan 17
United Airlines Logo
6:00 am - 4:20 pmDSM-GCM
9h 20m1 stop
United Airlines Logo
2:50 pm - 9:36 pmGCM-DSM
7h 46m1 stop
$1,561United Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to the Cayman Islands flights

Get data-powered insights and trends into flights from Des Moines to the Cayman Islands to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to the Cayman Islands?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Cayman Islands were found on American Airlines ($576) and Delta ($601).


Good to know

Low seasonAugust
Cheapest flight$576
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly and prices are also 18% lower on average.
Flight from Des Moines to George Town

FAQs - booking Cayman Islands flights

  • How does KAYAK find such low prices on flights from Des Moines to the Cayman Islands?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Cayman Islands.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Cayman Islands?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Cayman Islands is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Cayman Islands?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Cayman Islands with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Cayman Islands?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Cayman Islands up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Cayman Islands?

    The cheapest time of day to fly to the Cayman Islands is generally in the morning, when round-trip flights cost $608 on average. Morning departures are around 5% cheaper than evening flights, on average. The most expensive time of day to fly to the Cayman Islands is generally in the evening, which is peak travel time and where the average cost of a ticket is $638.

Reviews of the top airlines flying from Des Moines to the Cayman Islands

 
Need help choosing which airline to fly with from Des Moines to the Cayman Islands? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8900 reviews
6.6Food
8.1Crew
7.7Boarding
7.1Entertainment
7.3Comfort
Airline reviews

Terrible. Delayed 7 hours, and cancelled the flight, leaving me stranded and out of pocket $500 for an alternative last minute flight

2.0 MediocreV, Jul 2025MIA - EWR
Read more United Airlines reviews

Terrible. Delayed 7 hours, and cancelled the flight, leaving me stranded and out of pocket $500 for an alternative last minute flight

Was on time until within 1 hour of flight-how does that happen? Staff very friendly.

the delay for 3 hours was understandable due to weather conditions but the flight should’ve provided some on flight compensations or at least provide more food.

Weather delay in Chicago?. No sense of urgency to make connection in Chicago for our connecting flight that wasn't delayed. Connection was missed.

Our flight was understandably diverted to a small regional airport in Laramie, Wyoming due to weather conditions, which I fully recognize and appreciate. However, the low rating stems from the experience that followed: passengers remained on board for over an hour without the option to deplane and stretch, despite the aircraft being stationary. Although the pilot opened the cabin door, only he was permitted to exit. Meanwhile, passengers grew increasingly uncomfortable as warm summer air entered the cabin through the open door, and being in the second row meant we were impacted immediately. While the flight attendants made efforts to keep everyone at ease, I believe allowing passengers to deplane briefly, given the extended delay, would have significantly improved the overall experience.

I never flew. Flight was canceled. DIA worst airport in the country. Avoid at all costs.

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

The best airline I have ever travel , really good customer service, attention and service !!

United could have one single once of customer service. No human United employee would help me with the invalid mileage plus number, they said I had to speak with the computer.

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

We had to turn around and head back to Manchester. Problem with a plane engine.

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

Very poor delay in dfw was really bad n long

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Because of rescheduling, they had to put me on a flight that didn't go through Dallas

It was very difficult to stretch my knee out and I am very short. I also had a torn tendon in my knee which made it extra uncomfortable anyways. My husband is 6'2" and I can't imagine him flying in that plane.

3 hour weather delay followed by 1 hour (and counting) maintenance delay. UGH!

Couldn’t get the door on the plane to close leading to a nearly 2 hour delay. But, hey at least they didn’t cancel the flight.

Flight was cancelled 3 hrs AFTER etd. Thetefore Missed connection from JFK to New Zealand . No accommodation provided… This cost ne aporox 1000 USD in extra expenses and turned whst should have been a 24 hr trip ftom Boston - New Zealand into a VERY expensive , late 70+ hr nightmare … Complete nonsense!!!

After we'd boarded , they canceled the flight. The crew didn't even know , we just all received text messages. Then after they deplaned us , AA was just like "too bad, go F your self, we sure ain't gonna help you"

Everything you need to know for your flight from Des Moines to the Cayman Islands

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