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$1,153 Find Cheap Flights from Des Moines to Chile - Compare and Save

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Cheap Flights from Des Moines to Chile

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Santiago
Santiago1 stop$1,153
Punta Arenas
Punta Arenas2 stops$1,923
Santiago
Santiago1 stop$1,153
Punta Arenas
Punta Arenas2 stops$1,923

Book Cheap Des Moines to Chile Plane Tickets

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Chile

Tue, Jan 5 - Tue, Mar 2
LATAM Airlines Logo
5:45 am - 7:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
22h 55m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
11:10 pm - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
14h 08m1 stop Atlanta Hartsfield-Jackson
$1,153LATAM Airlines
Tue, Jan 5 - Tue, Mar 2
LATAM Airlines Logo
11:04 am - 7:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
17h 36m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
7:40 am - 10:29 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
17h 49m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,158LATAM Airlines
Tue, Jan 5 - Tue, Mar 2
LATAM Airlines Logo
11:04 am - 7:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
17h 36m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
8:35 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 43m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson
$1,162LATAM Airlines
Tue, Jan 5 - Tue, Mar 2
LATAM Airlines Logo
5:15 pm - 7:55 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
35h 40m3 stops Atlanta Hartsfield-Jackson Miami Punta Cana
LATAM Airlines Logo
8:35 am - 4:27 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
34h 52m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson
$1,167LATAM Airlines
Tue, Jan 5 - Tue, Mar 2
LATAM Airlines Logo
5:15 pm - 7:55 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
35h 40m3 stops Atlanta Hartsfield-Jackson Miami Punta Cana
LATAM Airlines Logo
11:10 pm - 10:29 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
26h 19m2 stops Miami Atlanta Hartsfield-Jackson
$1,167LATAM Airlines
Mon, Jan 4 - Tue, Mar 2
Delta Logo
11:04 am - 6:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
16h 36m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:25 pm - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
16h 53m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,168Delta
Mon, Jan 4 - Tue, Mar 2
Delta Logo
5:45 am - 6:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
21h 55m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:10 pm - 4:27 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
20h 17m1 stop Atlanta Hartsfield-Jackson
$1,168Delta
Sun, Jan 3 - Tue, Mar 2
American Airlines Logo
4:01 pm - 8:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
12h 59m1 stop Dallas/Fort Worth
American Airlines Logo
11:45 pm - 6:54 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
22h 09m1 stop Dallas/Fort Worth
$1,168American Airlines
Sun, Jan 3 - Tue, Mar 2
American Airlines Logo
9:53 am - 8:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
19h 07m2 stops Chicago O'Hare Intl Dallas/Fort Worth
American Airlines Logo
10:15 pm - 3:22 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
20h 07m2 stops Miami Dallas/Fort Worth
$1,172American Airlines
Mon, Jan 4 - Tue, Mar 2
Delta Logo
6:20 am - 6:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
21h 20m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson
Delta Logo
11:10 pm - 4:27 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
20h 17m2 stops Miami Atlanta Hartsfield-Jackson
$1,172Delta
Booking Insights

Price, demand and travel trends for Des Moines to Chile flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Des Moines to Chile right now?

The cheapest fare from Des Moines to Chile in the last week was $1,153 round-trip, to Santiago Arturo Merino Benitez (SCL).

Which airport in Chile is the cheapest to fly to from Des Moines?

Based on KAYAK data from the past 12 months, the cheapest airports to fly into Chile are:

• Santiago Arturo Merino Benitez (SCL) from $1,169
• Puerto Natales Teniente J. Gallardo (PNT) from $2,446

What’s the cheapest day to fly from Des Moines to Chile?

Thursday tends to be the cheapest day to fly from Des Moines to Chile, while Friday is the most expensive. Fares run about 67% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from Des Moines to Chile?

Data from the past 12 months shows it's cheapest to fly to Chile during the evening with average prices of $1,112. The morning is the most expensive time to fly, with average prices of $1,475.

Find deals

Key details for Des Moines to Chile flights

Low season

August

Cheapest flight

$1,153
Round-trip flight from Des Moines to Santiago

Your Des Moines to Chile flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Des Moines to Chile?

    Fares from Des Moines to Chile are around their usual level right now. A round-trip under $941 is considered a good deal, so it's worth keeping an eye out, or setting a Price Alert to catch price changes.

  • How much should I budget for a flight from Des Moines to Chile?

    Over the past 12 months, round-trip fares from Des Moines to Chile have ranged from $941 to $1,586.

  • What are the main airports serving Chile?

    Flights to Chile use two main airports, Santiago Arturo Merino Benitez (SCL) and Puerto Natales Teniente J. Gallardo (PNT).

  • What airlines fly nonstop from Des Moines to Chile?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Des Moines to Chile. One-stop options include Delta and American Airlines.

  • Which cabin classes are available on flights from Des Moines to Chile?

    On flights from Des Moines to Chile you can only book Economy Class.

  • What are some popular landmarks in Chile?

    KAYAK travelers' favorite landmarks in Chile include:

    • Estadio Nacional Julio Martinez Pradanos
    • Espacio Riesco Convention and Exhibition Center
    • Costanera Center
    • Plaza de Armas

Your guide to booking Des Moines to Chile flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your travel dates are flexible, book your trip for October when flights are typically cheapest and avoid January when prices are at their highest.
  • Flying on Thursday is usually the cheapest. Flights on Friday cost about 67% more on average, so being flexible with your travel dates could help you save.
  • If you're looking to save, Santiago Arturo Merino Benitez (SCL) is the cheapest airport to fly into from Des Moines. If you have onward travel, don't forget to factor in the cost of your journey by train, bus or domestic flight.
  • Start your trip in Santiago, which is the most popular destination in Chile. From there, it's easy to continue on to other popular destinations such as Viña del Mar, Puerto Natales and San Pedro de Atacama.

Reviews of the top airline flying from Des Moines to Chile

 
Need help choosing which airline to fly with from Des Moines to Chile? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1975 reviews
7.0Entertainment
7.3Comfort
8.0Crew
7.5Boarding
6.8Food
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

More options for your flight from Des Moines to Chile

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