$625 Find Cheap Flights from Des Moines to Chile - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Chile departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Des Moines to Chile

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago2 stops$969
Punta Arenas
Punta Arenas3 stops$1,563
Santiago
Santiago2 stops$969
Punta Arenas
Punta Arenas3 stops$1,563

Book Cheap Des Moines to Chile Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Chile that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Chile

Tue, Dec 29 - Thu, Feb 25
LATAM Airlines Logo
6:30 pm - 5:35 am
DSM
-
SCL
32h 05m
2 stops
LATAM Airlines Logo
7:40 am - 10:29 pm
SCL
-
DSM
17h 49m
2 stops
$969LATAM Airlines
Tue, Dec 29 - Thu, Feb 25
American Airlines Logo
11:32 am - 7:45 am
DSM
-
SCL
17h 13m
1 stop
American Airlines Logo
11:45 pm - 10:46 am
SCL
-
DSM
14h 01m
1 stop
$975American Airlines
Tue, Dec 29 - Thu, Feb 25
American Airlines Logo
9:26 am - 7:45 am
DSM
-
SCL
19h 19m
2 stops
American Airlines Logo
11:45 pm - 10:46 am
SCL
-
DSM
14h 01m
1 stop
$980American Airlines
Tue, Dec 29 - Thu, Feb 25
LATAM Airlines Logo
2:15 pm - 7:40 am
DSM
-
SCL
14h 25m
1 stop
LATAM Airlines Logo
12:10 am - 10:18 am
SCL
-
DSM
13h 08m
1 stop
$1,006LATAM Airlines
Tue, Dec 29 - Thu, Feb 25
LATAM Airlines Logo
6:30 pm - 6:35 am
DSM
-
SCL
33h 05m
2 stops
LATAM Airlines Logo
12:10 am - 10:18 am
SCL
-
DSM
13h 08m
1 stop
$1,016LATAM Airlines
Thu, Aug 20 - Thu, Aug 27
LATAM Airlines Logo
6:35 pm - 4:40 am
DSM
-
SCL
33h 05m
2 stops
LATAM Airlines Logo
7:35 am - 10:43 am
SCL
-
DSM
28h 08m
2 stops
$1,118LATAM Airlines
Tue, Aug 18 - Tue, Aug 25
LATAM Airlines Logo
6:35 pm - 5:55 am
DSM
-
SCL
34h 20m
2 stops
LATAM Airlines Logo
5:10 am - 10:43 am
SCL
-
DSM
30h 33m
2 stops
$1,131LATAM Airlines
Tue, Aug 18 - Tue, Aug 25
LATAM Airlines Logo
6:35 pm - 5:55 am
DSM
-
SCL
34h 20m
2 stops
LATAM Airlines Logo
5:10 am - 10:43 am
SCL
-
DSM
30h 33m
2 stops
$1,135LATAM Airlines
Mon, Aug 17 - Mon, Aug 24
LATAM Airlines Logo
6:35 pm - 10:49 am
DSM
-
SCL
39h 14m
3 stops
LATAM Airlines Logo
7:35 am - 10:37 pm
SCL
-
DSM
40h 02m
2 stops
$1,142LATAM Airlines
Thu, Aug 20 - Thu, Aug 27
Multiple Airlines Logo
8:00 am - 1:13 pm
DSM
-
PUQ
27h 13m
3 stops
Multiple Airlines Logo
1:59 pm - 2:05 pm
PUQ
-
DSM
26h 06m
2 stops
$1,563Multiple Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Chile flights

Get data-powered insights and trends into flights from Des Moines to Chile to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Chile?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Chile, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Chile is February, when tickets cost $0 (return) on average. On the other hand, the most expensive months are May and June, when the average cost of round-trip tickets is $1,705 and $1,350 respectively.

Find deals

Good to know

Cheapest flight$625
Most popular time to fly with an average 27% increase in price.
Flight from Des Moines to Santiago

FAQs - booking Chile flights

  • How does KAYAK find such low prices on flights from Des Moines to Chile?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Chile.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Chile?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Chile is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Chile?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Chile with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Chile?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Chile up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Chile

 
Need help choosing which airline to fly with from Des Moines to Chile? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1949 reviews
7.5Boarding
8.0Crew
7.0Entertainment
6.7Food
7.3Comfort
Airline reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

10.0 ExcellentSarah, Jan 2026
ANF - SCL
Read more LATAM Airlines reviews

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

The crew was amazing. The best in the last times. Great group of people.

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

Everything you need to know for your flight from Des Moines to Chile

Information on your arrival and departure airports

Des Moines (DSM)