$397 Find Cheap Flights from Des Moines to Chile

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Chile departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Des Moines to Chile

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago1 stop$741
Punta Arenas
Punta Arenas2 stops$1,008
Santiago
Santiago1 stop$741
Punta Arenas
Punta Arenas2 stops$1,008

Book Cheap Des Moines to Chile Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Chile that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Chile

Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
3:31 pm - 8:00 amDSM-SCL
13h 29m1 stop
American Airlines Logo
10:30 pm - 11:29 pmSCL-DSM
27h 59m1 stop
$741American Airlines
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Wed, Nov 26 - Wed, Dec 3
American Airlines Logo
12:54 pm - 9:00 amDSM-SCL
17h 06m2 stops
American Airlines Logo
11:15 pm - 2:55 pmSCL-DSM
18h 40m1 stop
$746American Airlines
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Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
6:05 am - 8:50 amDSM-SCL
23h 45m1 stop
United Airlines Logo
10:45 pm - 2:20 pmSCL-DSM
18h 35m2 stops
$756United Airlines
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Tue, Nov 25 - Tue, Dec 2
LATAM Airlines Logo
5:35 am - 5:50 amDSM-SCL
21h 15m2 stops
LATAM Airlines Logo
5:15 am - 10:34 pmSCL-DSM
20h 19m2 stops
$760LATAM Airlines
Find Deal
Tue, Nov 25 - Tue, Dec 2
LATAM Airlines Logo
2:17 pm - 7:40 amDSM-SCL
14h 23m1 stop
LATAM Airlines Logo
5:15 am - 10:34 pmSCL-DSM
20h 19m2 stops
$763LATAM Airlines
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Wed, Nov 26 - Wed, Dec 3
United Airlines Logo
2:52 pm - 8:50 amDSM-SCL
14h 58m1 stop
United Airlines Logo
10:45 pm - 2:12 pmSCL-DSM
18h 27m1 stop
$764United Airlines
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Wed, Nov 26 - Wed, Dec 3
Multiple Airlines Logo
9:44 am - 4:17 amDSM-SCL
39h 33m3 stops
Multiple Airlines Logo
9:29 pm - 10:21 pmSCL-DSM
27h 52m3 stops
$862Multiple Airlines
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Wed, Nov 26 - Wed, Dec 3
Multiple Airlines Logo
9:44 am - 4:17 amDSM-SCL
39h 33m3 stops
Multiple Airlines Logo
6:00 am - 10:21 pmSCL-DSM
43h 21m3 stops
$877Multiple Airlines
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Mon, Dec 8 - Fri, Dec 12
Delta Logo
2:16 pm - 12:50 pmDSM-SCL
19h 34m2 stops
Delta Logo
5:25 pm - 10:38 amSCL-DSM
20h 13m2 stops
$910Delta
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Mon, Dec 8 - Fri, Dec 12
Delta Logo
10:20 am - 7:40 amDSM-SCL
18h 20m2 stops
Delta Logo
11:30 pm - 4:58 pmSCL-DSM
20h 28m2 stops
$915Delta
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Booking Insights

KAYAK's insights & trends for Des Moines to Chile flights

Get data-powered insights and trends into flights from Des Moines to Chile to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Des Moines and Chile?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to Chile.

There is just one airline that flies from Des Moines to Chile direct and that is LATAM Airlines. The best round-trip deal found from LATAM Airlines for the route is to Santiago (SCL) and costs $843.

Which airlines provide the cheapest flights from Des Moines to Chile?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Chile were found on American Airlines ($741) and United Airlines ($756).

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Good to know

Low seasonOctober
Cheapest flight$397
Best time to beat the crowds with an average 28% drop in price.
Most popular time to fly with an average 46% increase in price.
Flight from Des Moines to Santiago

FAQs - booking Chile flights

  • How does KAYAK find such low prices on flights from Des Moines to Chile?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Chile.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Chile?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Chile is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Chile?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Chile with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Chile?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Chile up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Chile?

    The cheapest time of day to fly to Chile is generally in the evening, when round-trip flights cost $768 on average. Morning departures are around 41% more expensive than evening flights, on average. The most expensive time of day to fly to Chile is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,081.

Reviews of the top airline flying from Des Moines to Chile

 
Need help choosing which airline to fly with from Des Moines to Chile? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1864 reviews
7.6Boarding
8.0Crew
7.0Entertainment
7.3Comfort
6.7Food
Airline reviews

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

8.0 ExcellentLUIS JOSE, Sep 2025AEP - SCL
Read more LATAM Airlines reviews

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

It was a very good flight, no entertainment is the reason for not checking that box.

Everything you need to know for your flight from Des Moines to Chile

Information on your arrival and departure airports

Des Moines (DSM)

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