$438 Find Cheap Flights from Des Moines to Chile

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Chile departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Des Moines to Chile

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Santiago
Santiago2 stops$893
Punta Arenas
Punta Arenas3 stops$1,213
Santiago
Santiago2 stops$893
Punta Arenas
Punta Arenas3 stops$1,213

Book Cheap Des Moines to Chile Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Chile that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Chile

Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
5:45 am - 5:35 am
DSM
-
SCL
22h 50m
2 stops
LATAM Airlines Logo
11:05 pm - 5:45 pm
SCL
-
DSM
19h 40m
2 stops
$893LATAM Airlines
Wed, Apr 22 - Wed, Apr 29
LATAM Airlines Logo
6:31 pm - 2:05 pm
DSM
-
SCL
18h 34m
2 stops
LATAM Airlines Logo
8:40 pm - 11:05 am
SCL
-
DSM
15h 25m
1 stop
$898LATAM Airlines
Wed, Apr 22 - Wed, Apr 29
LATAM Airlines Logo
2:44 pm - 1:25 pm
DSM
-
SCL
21h 41m
3 stops
LATAM Airlines Logo
11:05 pm - 5:45 pm
SCL
-
DSM
19h 40m
2 stops
$902LATAM Airlines
Wed, Apr 22 - Wed, Apr 29
LATAM Airlines Logo
2:44 pm - 2:05 pm
DSM
-
SCL
22h 21m
2 stops
LATAM Airlines Logo
4:50 pm - 11:05 am
SCL
-
DSM
19h 15m
2 stops
$903LATAM Airlines
Thu, Apr 23 - Thu, Apr 30
LATAM Airlines Logo
11:51 am - 1:25 pm
DSM
-
SCL
24h 34m
3 stops
LATAM Airlines Logo
8:40 pm - 11:05 am
SCL
-
DSM
15h 25m
1 stop
$906LATAM Airlines
Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
2:44 pm - 7:15 am
DSM
-
SCL
15h 31m
1 stop
LATAM Airlines Logo
11:05 pm - 5:45 pm
SCL
-
DSM
19h 40m
2 stops
$907LATAM Airlines
Tue, Apr 21 - Tue, Apr 28
Delta Logo
2:44 pm - 7:15 am
DSM
-
SCL
15h 31m
1 stop
Delta Logo
8:40 pm - 5:45 pm
SCL
-
DSM
22h 05m
1 stop
$908Delta
Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
2:44 pm - 1:25 pm
DSM
-
SCL
21h 41m
3 stops
LATAM Airlines Logo
6:45 pm - 11:05 am
SCL
-
DSM
17h 20m
2 stops
$911LATAM Airlines
Tue, Apr 21 - Tue, Apr 28
LATAM Airlines Logo
2:44 pm - 1:25 pm
DSM
-
SCL
21h 41m
3 stops
LATAM Airlines Logo
11:05 pm - 5:45 pm
SCL
-
DSM
19h 40m
2 stops
$912LATAM Airlines
Mon, Apr 20 - Mon, Apr 27
LATAM Airlines Logo
11:51 am - 1:25 pm
DSM
-
SCL
24h 34m
3 stops
LATAM Airlines Logo
11:05 pm - 5:45 pm
SCL
-
DSM
19h 40m
2 stops
$913LATAM Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Chile flights

Get data-powered insights and trends into flights from Des Moines to Chile to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Chile?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Chile were found on LATAM Airlines ($903) and Delta ($908).

Find deals

Good to know

Cheapest flight$438
Flight from Des Moines to Santiago

FAQs - booking Chile flights

  • How does KAYAK find such low prices on flights from Des Moines to Chile?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Chile.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Chile?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Chile is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Chile?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Chile with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Chile?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Chile up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Chile

 
Need help choosing which airline to fly with from Des Moines to Chile? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1917 reviews
8.0Crew
6.7Food
7.3Comfort
7.5Boarding
7.0Entertainment
Airline reviews

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

2.0 MediocreTony, Feb 2026
LGA - ATL
Read more LATAM Airlines reviews

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Everything you need to know for your flight from Des Moines to Chile

Information on your arrival and departure airports

Des Moines (DSM)