DSM - SCL

$351 Find Cheap Flights from Des Moines to Santiago - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$1,075
Typical prices: $931-$1,823
Delta
Sat 12/29Sat 2/10
DSM - SCL • 1 stop
Cheapest one-way
$351
Typical prices: $622-$790
Multiple Airlines
Mon 10/1
DSM - SCL • 3 stops
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 33% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Houston George Bush Intcntl (IAH)
Cheapest • Avg $764 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 14h 35m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santiago (DSM-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santiago

Tue, Dec 29 - Wed, Feb 10
Delta Logo
11:34 am - 7:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
17h 06m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:25 pm - 4:27 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
23h 02m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson
$1,075Delta
Tue, Dec 29 - Wed, Feb 10
American Airlines Logo
7:02 am - 9:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
22h 58m2 stops Charlotte Douglas Miami
American Airlines Logo
10:15 pm - 1:16 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
18h 01m2 stops Miami Charlotte Douglas
$1,080American Airlines
Tue, Dec 29 - Wed, Feb 10
LATAM Airlines Logo
11:34 am - 7:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
16h 26m2 stops Atlanta Hartsfield-Jackson Miami
LATAM Airlines Logo
8:35 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 43m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson
$1,210LATAM Airlines
Thu, Oct 15 - Thu, Oct 22
LATAM Airlines Logo
3:03 pm - 7:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
37h 57m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
LATAM Airlines Logo
6:10 am - 10:42 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
30h 32m2 stops Rio de Janeiro–Galeão Intl Atlanta Hartsfield-Jackson
$1,250LATAM Airlines
Thu, Oct 15 - Thu, Oct 22
LATAM Airlines Logo
5:35 am - 8:15 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
24h 40m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
6:10 am - 10:42 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
30h 32m2 stops Rio de Janeiro–Galeão Intl Atlanta Hartsfield-Jackson
$1,265LATAM Airlines
Wed, Oct 14 - Wed, Oct 21
LATAM Airlines Logo
6:54 pm - 2:35 pmDSM  Des Moines-SCL Santiago Arturo Merino Benitez
41h 41m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
LATAM Airlines Logo
5:15 pm - 10:42 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
43h 27m2 stops Rio de Janeiro–Galeão Intl Atlanta Hartsfield-Jackson
$1,269LATAM Airlines
Thu, Oct 15 - Thu, Oct 22
LATAM Airlines Logo
3:03 pm - 8:15 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
15h 12m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
8:40 pm - 10:42 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
16h 02m1 stop Atlanta Hartsfield-Jackson
$1,293LATAM Airlines
Tue, Oct 13 - Tue, Oct 20
LATAM Airlines Logo
5:35 am - 8:15 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
24h 40m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
8:35 am - 10:42 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 07m2 stops Rio de Janeiro–Galeão Intl Atlanta Hartsfield-Jackson
$1,305LATAM Airlines
Wed, Oct 14 - Wed, Oct 21
American Airlines Logo
9:48 am - 8:10 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
20h 22m2 stops Dallas/Fort Worth Miami
American Airlines Logo
9:30 pm - 3:11 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
19h 41m2 stops Miami Dallas/Fort Worth
$1,309American Airlines
Tue, Oct 13 - Tue, Oct 20
LATAM Airlines Logo
5:35 am - 8:15 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
24h 40m1 stop Atlanta Hartsfield-Jackson
LATAM Airlines Logo
1:20 pm - 10:42 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
23h 22m2 stops Rio de Janeiro–Galeão Intl Atlanta Hartsfield-Jackson
$1,310LATAM Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Santiago with more confidence.

How much is a round-trip flight from Des Moines to Santiago?

Round-trip flights from Des Moines to Santiago start at $1,075. Prices are typical for this route right now, with typical round-trip fares ranging from $931 to $1,823. The lowest price found in the past 5 days was $1,075 on Delta.

What's the cheapest day of the week to fly from Des Moines to Santiago?

Thursday is the cheapest day of the week to fly from Des Moines to Santiago, it is 40% cheaper than the average day. Monday is the most expensive day with flight prices 38% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Key details for Des Moines to Santiago flights

Low season

August

Cheapest flight

$351
Most popular time to fly with an average 5% increase in price.
Flight from Des Moines to Santiago

When to book flights from Des Moines to Santiago

Are your dates flexible? Find out the best times to travel from Des Moines to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Santiago flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Des Moines to Santiago?

    Flights from Des Moines to Santiago usually depart from Des Moines (DSM) and arrive at Santiago Arturo Merino Benitez (SCL).

  • What cabin classes can I book on flights from Des Moines to Santiago?

    Only Economy Class is available on flights from Des Moines to Santiago.

  • Which airports do connecting flights from Des Moines to Santiago pass through?

    One-stop flights from Des Moines to Santiago most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 73% of one-stop connections
    • Houston George Bush Intcntl (IAH) - 18% of one-stop connections
    • Dallas/Fort Worth (DFW) - 9% of one-stop connections

    Atlanta Hartsfield-Jackson (ATL) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Des Moines to Santiago?

    Yes. Being flexible with your travel dates can save you up to 57% on the Des Moines to Santiago route. Thursday is the cheapest departure day at $814 round-trip on average, while Monday is the most expensive at $1,875, a difference of $1,061. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Parque Arauco, University of Chile and Estadio Nacional Julio Martinez Pradanos. These are among the most viewed places in Santiago on KAYAK.

  • How long is a flight from Des Moines to Santiago?

    A nonstop flight from Des Moines to Santiago takes 0h 00m, covering 5,374 miles.

  • Do I need a passport to fly from Des Moines to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Des Moines to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $1,075 to $2,646. That means the highest observed fare was about 2x higher than the lowest one.

  • How are flight prices from Des Moines to Santiago looking right now?

    One-way fares from Des Moines to Santiago are currently lower than usual. Average one-way flight prices are about $555, which is 30% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Des Moines to Santiago?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 14h 35m, compared with 15h 14m via Dallas/Fort Worth (DFW) and 16h 41m via Houston George Bush Intcntl (IAH).

  • What is the time difference between Des Moines and Santiago?

    Santiago is 1 hour ahead of Des Moines (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:
    · Lucano
    · United Rent-A-Car
    · Rosselot
    · FlexWays
    · Alamo

  • How much should I expect to pay for a Des Moines to Santiago flight?

    Round-trip flights from Des Moines to Santiago range from $931 to $1,823, with an average of $1,350 over the past 12 months. Anything below $931 counts as a good deal.

Your guide to booking Des Moines to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Thursday departure instead of Monday. On this route, Thursday flights average $814 - about $1,061 less than Monday (57% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Santiago trip for January. Fares historically average $906 round-trip in that month - typically $969 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.
    - Holiday Inn Santiago - Airport Terminal By IHG

Everything you need to know for your flight from Des Moines to Santiago

Information on your arrival and departure airports

Des Moines (DSM)
Santiago (SCL)