DSM - SCL

$804 Find Cheap Flights from Des Moines to Santiago

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santiago departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santiago, as well as popular online travel agencies
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Flights Deals

Cheap Flight Deals from Des Moines to Santiago (DSM-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Des Moines to Santiago

KAYAK's recommended round-trip deals from the most popular airlines that fly from Des Moines to Santiago.
Discover the best prices for you by selecting your travel dates on KAYAK.
Delta Logo
11:04 am - 6:40 amDSM-SCL
17h 36m2 stops
Delta Logo
5:00 pm - 10:18 amSCL-DSM
19h 18m2 stops
$804Delta
Find Deal
Tue, Oct 7 - Tue, Oct 21
LATAM Airlines Logo
2:14 pm - 8:00 amDSM-SCL
15h 46m1 stop
LATAM Airlines Logo
9:40 pm - 10:18 amSCL-DSM
14h 38m1 stop
$854LATAM Airlines
Find Deal
Tue, Oct 7 - Tue, Oct 21
LATAM Airlines Logo
6:30 pm - 3:00 pmDSM-SCL
18h 30m2 stops
LATAM Airlines Logo
12:25 am - 10:23 pmSCL-DSM
23h 58m2 stops
$870LATAM Airlines
Find Deal
Tue, Oct 7 - Mon, Oct 20
LATAM Airlines Logo
6:30 pm - 1:25 pmDSM-SCL
16h 55m2 stops
LATAM Airlines Logo
5:55 pm - 10:23 pmSCL-DSM
30h 28m3 stops
$980LATAM Airlines
Find Deal
Tue, Oct 7 - Tue, Oct 21
LATAM Airlines Logo
6:30 pm - 4:30 amDSM-SCL
32h 00m3 stops
LATAM Airlines Logo
12:25 am - 10:23 pmSCL-DSM
23h 58m2 stops
$988LATAM Airlines
Find Deal
Tue, Oct 7 - Mon, Oct 20
LATAM Airlines Logo
6:30 pm - 4:30 amDSM-SCL
32h 00m3 stops
LATAM Airlines Logo
5:55 pm - 10:23 pmSCL-DSM
30h 28m3 stops
$1,001LATAM Airlines
Find Deal
Tue, Oct 7 - Tue, Oct 21
Delta Logo
11:24 am - 7:00 amDSM-SCL
18h 36m1 stop
Delta Logo
11:00 am - 12:29 pmSCL-DSM
26h 29m2 stops
$1,188Delta
Find Deal
Fri, Jun 13 - Fri, Jun 20
Copa Airlines Logo
8:00 am - 5:04 amDSM-SCL
20h 04m2 stops
Copa Airlines Logo
12:24 am - 5:46 pmSCL-DSM
18h 22m2 stops
$1,997Copa Airlines
Find Deal
Fri, Jun 13 - Thu, Jun 19
Copa Airlines Logo
8:00 am - 5:04 amDSM-SCL
20h 04m2 stops
Copa Airlines Logo
12:13 am - 5:59 pmSCL-DSM
18h 46m2 stops
$2,351Copa Airlines
Find Deal
Sat, Jun 14 - Fri, Jun 20
Avianca Logo
8:00 am - 4:15 amDSM-SCL
19h 15m2 stops
Avianca Logo
2:30 pm - 9:25 pmSCL-DSM
31h 55m2 stops
$4,129Avianca
Find Deal
Fri, Jun 13 - Fri, Jun 20
Useful Info

KAYAK's insights & trends for Des Moines to Santiago flights

Get data-powered insights and trends into flights from Des Moines to Santiago to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santiago?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Santiago were found on Delta ($804) and LATAM Airlines ($854).

Good to know

Cheapest flight$804
Flight from Des Moines to Santiago

When to book flights from Des Moines to Santiago

Are your dates flexible? Find out the best times to travel from Des Moines to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santiago

  • What is the cheapest flight from Des Moines to Santiago?

    In the last 3 days, the lowest price for a flight from Des Moines to Santiago was $804 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Santiago?

    Yes, you’ll need a passport to travel to Santiago from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santiago?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santiago, also known as Santiago Arturo Merino Benitez.

  • Which aircraft models fly most regularly from Des Moines to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santiago?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Des Moines and Santiago, with Star Alliance being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Des Moines to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airlines flying from Des Moines to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7934 reviews
7.3Food
7.9Entertainment
8.5Crew
7.9Comfort
8.2Boarding
Airline reviews

Our bag was lost so that made unnecessary chaos On our trip

6.0 GoodBarbara, Apr 2025JFK - FCO
Read more Delta reviews

Our bag was lost so that made unnecessary chaos On our trip

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

It was an overnight flight and I desperately needed coffee before we landed, but Delta does only one beverage service, and that is shortly after takeoff, not before landing at 5 am.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Took off on time and successfully avoided weather that looked to be a problem along the way

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Everything you need to know for your flight from Des Moines to Santiago

Information on your arrival and departure airports

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