$387 Find Cheap Flights from Des Moines to Italy

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Italy departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Des Moines to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Milan
Milan3 stops$736
Florence
Florence2 stops$873
Turin
Turin2 stops$949
Milan
Milan3 stops$736
Florence
Florence2 stops$873
Turin
Turin2 stops$949

Book Cheap Des Moines to Italy Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Italy that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Italy

Fri, Dec 11 - Wed, Dec 16
Air Canada Logo
5:03 pm - 10:05 am
DSM
-
MXP
58h 02m
3 stops
Air Canada Logo
1:05 pm - 9:17 pm
MXP
-
DSM
39h 12m
2 stops
$736Air Canada
Fri, Dec 11 - Wed, Dec 16
Air Canada Logo
8:15 pm - 10:05 am
DSM
-
MXP
54h 50m
3 stops
Air Canada Logo
1:05 pm - 11:01 pm
MXP
-
DSM
40h 56m
3 stops
$741Air Canada
Sun, Dec 6 - Thu, Dec 10
United Airlines Logo
6:15 am - 7:30 am
DSM
-
MXP
18h 15m
2 stops
United Airlines Logo
11:20 am - 10:30 pm
MXP
-
DSM
18h 10m
2 stops
$745United Airlines
Tue, Oct 13 - Wed, Oct 21
KLM Logo
5:45 am - 9:25 am
DSM
-
MXP
20h 40m
1 stop
KLM Logo
11:40 am - 10:29 pm
MXP
-
DSM
17h 49m
1 stop
$767KLM
Tue, Oct 6 - Wed, Oct 14
United Airlines Logo
11:27 am - 1:20 pm
DSM
-
MXP
18h 53m
1 stop
United Airlines Logo
12:20 pm - 12:34 pm
MXP
-
DSM
31h 14m
2 stops
$771United Airlines
Mon, Aug 3 - Wed, Aug 19
Delta Logo
5:30 pm - 3:55 pm
DSM
-
LIN
15h 25m
2 stops
Delta Logo
6:25 am - 4:50 pm
LIN
-
DSM
17h 25m
2 stops
$823Delta
Tue, Aug 11 - Thu, Aug 20
Air France Logo
10:59 am - 12:40 pm
DSM
-
FCO
18h 41m
1 stop
Air France Logo
9:00 am - 5:11 pm
FCO
-
DSM
15h 11m
1 stop
$824Air France
Tue, Oct 13 - Tue, Oct 27
Delta Logo
10:55 am - 1:55 pm
DSM
-
LIN
20h 00m
2 stops
Delta Logo
6:30 am - 7:12 pm
LIN
-
DSM
18h 42m
2 stops
$850Delta
Wed, Jul 29 - Wed, Aug 5
KLM Logo
5:52 pm - 4:50 pm
DSM
-
FLR
15h 58m
2 stops
KLM Logo
6:10 pm - 5:50 pm
FLR
-
DSM
30h 40m
2 stops
$919KLM
Mon, Jul 27 - Mon, Aug 3
Air France Logo
5:52 pm - 2:35 pm
DSM
-
VCE
13h 43m
2 stops
Air France Logo
9:10 pm - 4:50 pm
VCE
-
DSM
50h 40m
2 stops
$955Air France
Booking Insights

KAYAK's insights & trends for Des Moines to Italy flights

Get data-powered insights and trends into flights from Des Moines to Italy to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Italy?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Italy, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Italy is January, when tickets cost $457 (return) on average. On the other hand, the most expensive months are June and September, when the average cost of round-trip tickets is $675 and $662 respectively.

Good to know

Low seasonMay
Cheapest flight$387
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 23% increase in price.
Flight from Des Moines to Milan Malpensa Airport

FAQs - booking Italy flights

  • How does KAYAK find such low prices on flights from Des Moines to Italy?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Italy.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Italy?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Italy is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Italy?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Italy with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Italy?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Italy up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Des Moines to Italy

 
Need help choosing which airline to fly with from Des Moines to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8397 reviews
7.2Food
8.1Boarding
8.5Crew
7.8Comfort
7.8Entertainment
Airline reviews

Flight delayed four separate times. I’m now one hour hours late to landing.

2.0 MediocreTravis, Jun 2026
SFO - LAX
Read more Delta reviews

Flight delayed four separate times. I’m now one hour hours late to landing.

worst flight ever from Delta, it got delayed and kept on delaying..

Should never have had to go to Detroit from Orlando back to Tennessee!

Got rerouted from a straight flight from Orlando to Atlanta to Knoxville to a flight from Orlando to Detroit to Knoxville! Seriously!! Flight delay out of Detroit! Long day for what should have been a pretty easy travel day!

Two delays on two separate planes with parts they could not easily find and replace.

Checkin was good, fllight ws good. Onlly complaint is lack of foot on 6 hour flight from Seattle to Boston. Snacks were flimsy - chips and cookies. could have offered something more substantial for such a long flight. I know you can buy food in airport but for the price you pay for a ticket, they should step up for the passengers.

Only beverages were offered to first class and I thought the flight attendant could have also served the Delta Comfort as well instead of sitting down and staring at her phone and walking past all of us to the back of the plane to charge her phone more. There was a complete lack of turbulence and was safe enough for flights attendant to walk around in the front of the plane, collect trash and serve a few people water and turn off the seat belt light. Also didn’t enforce people putting their seats into the upright position and allowed two passengers to remain reclined during landing. They seemed out to lunch completely. Usually my experience on Delta is much better.

Long story short, it was one of the better flight experiences I've had in some time when compared with other airlines.

Flight was great! This flight from Atlanta was even better than when I paid for Comfort from SNA to Atlanta.

Connection flights should be spaced out farther because too close I missed my connection.

As always, it’s a pleasure to travel with KLM. It is one of my favorite airlines.

Outstanding even though the 330 was one of the oldest in the fleet. The difference was the attentiveness and responsiveness of a really experienced flight attendant. For airline food great variety of interesting choices and good tastes supported by a good wine selection.

Brand new plane lots of room the snack was very flavourful and enjoyable

There were no charge points for phones on the economy seats. The seats were comfortable overall. Food was okay.. flight was on time

The flight was delayed. The aircraft was unclean. Promised seat was not given due to change in Aircraft. Not one crew on ground was in a position to give any response. Amsterdam Airport is AVIODABLE Over crowded. Over Expensive. Poor Services.

It was really nice experience by flying this klm flight.I personally recommend everyone to please try this klm flight

The crew were unprofessional with a racist element. I was physically abused as well from one of the crew members

Crew is not the cheerful type. very slow meal service (this is their style as have flown this many times)

I’m grateful for the KLM Air France shuttle bus service to Ottawa. However due to construction and other issues related to the chaotic Uber pickup system at YUL, it’s a challenge to find the Kelios bus service to Ottawa. The signs are not clear or even available. No staff to guide passengers. It’s a stressful experience.

Terrible last row seats many seats available but no offer to move to better seat

Everything is good except the seats are tightened no rooms for the legs,

The flight crew was exceptionally friendly and helpful. Also the seats were comfortable and roomier than many other airlines.

The plane's pilots, including the captain himself, thanked me for the flight. I know it's just marketing, but it was really nice to see these people. It's a great idea. Airplane food is never "good," but the entire crew and flight organization were top-notch. I really liked Delta, and I think I've traveled all over the world, and that was something new for me. Maybe even the old planes, the B767, but next time I have a choice, Delta will be my first choice. Thank you, a satisfied passenger :)

They lost my bag and I still haven’t received it yet

They lost my bag and I still have not received it

Not consistent with the food quality (I mean taste not freshness)

Safe and stable made me sleepy and I slept and dreamt 😂😂😂😂

Food was really mediocre for premium economy in comparison to other airlines… the crew was nowhere to be found… 14 hour flight…

I don’t like that an equipment change caused my seat to change from 23A to 44A. The boarding was also delayed. The crew were excellent, however and very attentive. The food was not bad.

Our flight crew were terrific. And they handle a difficult passenger with finesse.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

I was promised by United Airline (operated by ANA) that I will be seated together with my kids as I am the only adult flying with two minors. We did not get seats together in our 11 hours flight from LA to Tokyo. When asked at the gate, ANA representative said United Airline should have informed them that there is a parent flying with two minors. He said they can’t do anything in the system as the flight is full. He ask me to ask passengers next to me and the kids if they are willing to change seats. This is ridiculous! However, I went in the flight and asked other passages but no one willing to change seats. 11 hours and we were seating separately. I was very disappointed with this. It made things super inconvenient for me.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

Flight cancelled instead of leaving Friday am now, maybe, leaving Sunday

The pilot had to extend the flight time from san antonio to Houston to burn off fuel. This caused a lot of unnecessary stress since we had a tight connection to Aruba. And with no other flights going to Aruba we were worried about spending a night in Houston. We had to to run to our connection because of the flight crews mistake. Not happy.

Service was professional and quick. Premium economy seat was comfortable given the class

one of the flight attendants on the Dallas to frankfurt leg was somewhat rude..

I'm a United 1K member and have ben for 10 years. The gate agent had no control over the boarding process and had us passengers queued for hours as delays were announced. On the plane, the overhead air nozzle was broken so col over was powering through on me and the passenger next to me. Not a great experience for a million miler on United. Feel free to contact me. Josh Smigel - DM426089

Like: departed and arrived on time. Unlike: Food options for purchase allways bad, 1 of 2 of the crew members not very friendly at all. Seats and leg room aweful. At this point I am thinking on switching to AA.

Over 5 hour delay with minimal updates or ability to standby for alternative flights. During boarding and 1 hr+ wait for takeoff, seats were drenched w water from air conditioning condensation and always leftover crumbs on carpet and seats

Everything you need to know for your flight from Des Moines to Italy

Information on your arrival and departure airports