$349 Find Cheap Flights from Des Moines to Italy - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 25% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Italy

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
Milan
Milan1 stop$708
Florence
Florence2 stops$745
Turin
Turin2 stops$1,082
Milan
Milan1 stop$708
Florence
Florence2 stops$745
Turin
Turin2 stops$1,082
Booking Insights

Price, demand and travel trends for Des Moines to Italy flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What are the cheapest fares from Des Moines to Italy right now?

Here are the cheapest round-trip fares from Des Moines to Italy on KAYAK in the last week:

• Rome Fiumicino (FCO) from $686
• Milan Malpensa (MXP) from $708
• Bari Palese (BRI) from $721
• Florence Peretola (FLR) from $745
• Venice Marco Polo (VCE) from $762

What’s the cheapest month to fly from Des Moines to Italy?

February is the cheapest time of year to fly, with average fares of $718. Prices are highest in October, when average flight costs increase to around $1,150.

Which airport in Italy is the cheapest to fly to from Des Moines?

Based on KAYAK data from the past 12 months, the cheapest airports to fly into Italy are:

• Milan Linate (LIN) (avg. price $728)
• Milan Malpensa (MXP) (avg. price $742)
• Rome Fiumicino (FCO) (avg. price $1,013)

What’s the cheapest day to fly from Des Moines to Italy?

Tuesday tends to be the cheapest day to fly from Des Moines to Italy, while Thursday is the most expensive. Fares run about 16% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from Des Moines to Italy?

Data from the past 12 months shows it's cheapest to fly to Italy during the morning with average prices of $938. The afternoon is the most expensive time to fly, with average prices of $1,056.

Key details for Des Moines to Italy flights

Low season

December

Cheapest flight

$349
Beat the crowds with an average 45% drop in travelers.
The most popular month to fly with an average 50% increase in travelers.
One-way flight from Des Moines to Rome Fiumicino Airport

Your Des Moines to Italy flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Des Moines to Italy?

    Yes. Fares from Des Moines to Italy are low right now. As a rule of thumb, a round-trip under $759 (cheaper than most fares this year) is a good deal, so if you spot one at or below that, it's a good time to book.

  • How much should I budget for a flight from Des Moines to Italy?

    Over the past 12 months, round-trip fares from Des Moines to Italy have ranged from $759 to $1,250.

  • What are the main airports serving Italy?

    Italy has 43 airports. The three busiest are Rome Fiumicino (FCO) (53% of arrivals), Florence Peretola (FLR) (18%) and Milan Malpensa (MXP) (5%).

  • What airlines fly nonstop from Des Moines to Italy?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Des Moines to Italy. One-stop options include:

    • Delta
    • United Airlines
    • American Airlines

  • Which cabin classes are available on flights from Des Moines to Italy?

    On flights from Des Moines to Italy you can book Economy Class, Premium Economy Class, Business Class or First Class.

  • What are some popular landmarks in Italy?

    KAYAK travelers' favorite landmarks in Italy include:

    • Piazza Navona
    • Colosseum
    • Pantheon
    • Fontana di Trevi

Your guide to booking Des Moines to Italy flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your travel dates are flexible, book your trip for February when flights are typically cheapest and avoid October when prices are at their highest.
  • Flying on Tuesday is usually the cheapest. Flights on Thursday cost about 16% more on average, so being flexible with your travel dates could help you save.
  • If you're looking to save, Milan Linate (LIN) is the cheapest airport to fly into from Des Moines. If you have onward travel, don't forget to factor in the cost of your journey by train, bus or domestic flight.
  • Start your trip in Rome, which is the most popular destination in Italy. From there, it's easy to continue on to other popular destinations such as Milan, Venice and Florence.

Reviews of the top 5 airlines serving from Des Moines to Italy

 
Need help choosing which airline to fly with from Des Moines to Italy? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
KLMOverall score based on 1595 reviews
7.4Food
7.2Entertainment
8.4Crew
7.7Comfort
7.8Boarding
Airline reviews

The flight itself was fine, food was expired and gross, staff were mostly amazing! KLM messed up rebooking for our first two flights that got cancelled and we almost didn’t make it to Amsterdam for an additional two days

4.0 OkayJessica, Sep 2026
Read more KLM reviews

The flight itself was fine, food was expired and gross, staff were mostly amazing! KLM messed up rebooking for our first two flights that got cancelled and we almost didn’t make it to Amsterdam for an additional two days

I think I previously submitted my feedback about flight lead Katherine in a different field by mistake. Please see those comments. Comments for Hyd to AMS are it was good. The flight lead and service met expectations for satisfactory high quality service but the flight lead did not stand out as exceptional as did the leads on the other two flights so I don’t remember anything specific one way or the other besides the fact I was satisfied.

Had to cancel and rebook, KLM connection was cancelled prior to departure, ended up flying to Munich on non-Delta carrier.

The crew were unprofessional with a racist element. I was physically abused as well from one of the crew members

They forgot to serve food and the crew was very unfriendly. Never experienced such a bad KLM flight. Usually fly from Toronto. New York was different.

Over 1 Hr delay. No APU so no AC on ground. Plane was hot during boarding and then they closed the doors over 20 minutes before engine start so interior of plane was steamy hot and stuffy. Could have been helped by opening doors until ready to depart.

My flight was delayed by 6 hours then I missed BOTH of my connecting flights, I then had to stay in the AIRPORT at JFK because soooooo many people also suffered from missing flights and there was no hotels available. I would like to be compensated for this experience! I had to stay in the airport for over 16 hours!

Cabin crew were excellent, very proffesional, polite and friendly, in flight snack was underwhelming, a packet of cheese biscuits, im sure KLM could run to a sandwich!

The baggage service at Malpensa was the worst ever. We wanted for over an hour without any information, they broke my suitcase, and the services of the local luggage services company was below any usual services level of a KLM partner.

All and all pretty good. It’s crowded but that is what flying is all about. But no complaints otherwise.

I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.

Excellent service, I love the soft blush pink mood lighting on the 767-400ER during meal service. The overhead gasper vents on the 767-400ER were also very strong with a lot of airflow to keep me comfortable on my flight.

Our bag was lost so that made unnecessary chaos On our trip

More up to date movies and a live TV option like ESPN, Fox News or CNN. All they had were movies and Spotify Music and some games. Also, wifi on international flights isn't free for Skymiles members like on domestic flights via T-Mobile.

7 hour delay for mechanical reasons Handled badly by crew and delta personnel

Flight was canceled so it was not a great experience. Boarded, then deboarded. Delayed, boarded a new plane then deboarded the 2nd plane and flight was canceled. Then booked a fight to Rome and took a train to Venice the next day. Lost an entire day +

They split our family into two trips due to flight overbooking. Horrible experience.

The plane was FREEZING SEATS UNCOMFORTABLE Otherwise smooth Thank you

Upon landing our breakfast were left, which means all the tray tables were were down for on landing . Isn’t there an FAA have rule about that

Crew was great. Food and entertainment was great. There was plenty of leg room sitting in a economy seat. That being said put thicker padding at the lower part of the seat. The person seated behind me was very tall and their knees were pushed into my back the entire flight. I understand having to move your legs but it was moving into my back for a 9 hour flight!

Our flight delayed, due to the incoming flight arriving late from Paris. AF caused us to miss our connecting flight, also booked through Air France directly. They couldn't accommodate us until later that night, and we had to be in AMS earlier than that. They won't do anything else to help us and wanted to charge us more money to rebook us too. Not great service, since it was all their fault.

Seats! The eternal problem in economy. They are like stones!!

Everything is good except the seats are tightened no rooms for the legs,

The plane's pilots, including the captain himself, thanked me for the flight. I know it's just marketing, but it was really nice to see these people. It's a great idea. Airplane food is never "good," but the entire crew and flight organization were top-notch. I really liked Delta, and I think I've traveled all over the world, and that was something new for me. Maybe even the old planes, the B767, but next time I have a choice, Delta will be my first choice. Thank you, a satisfied passenger :)

It was a great experience. The only thing I would have changed was that the bathrooms were never cleaned and they got very dirty.

Old airplanes small seats expensive tickets, not as expected overall and not comfortable according to the price

It was an OK flight with below mediocre service by their flight attendants

Wasted a lot of time trying to find the CDG lounge - it was not next to the connecting flight gate like the Air France staff said.

The only reason the overall rating wasn't "excellent" was due to problems in claiming luggage. The bags are delivered to the main area (Cinta 35) for domestic passengers, but to a DIFFERENT ROOM for international arrivees. After waiting 30 minutes, someone (who didn't appear to be from Air France or the airport) told us to go to another area. There we found our bags, which appeared to have been awaiting us for a while. We had to go through a bag check before leaving the airport. If we had been alerted to this possibility, or better yet, been to go directly to Cinta 34, we could have eliminated quite a bit of waiting.

I paid 3 this and dollars for two tickets. No food, minimum drink, confused service and very uncomfortable sear. There was zero difference between busy ness and tourist class. I received a pathetic apology

Everything was OK except the meals, that was overpriced chicken meat.

1 flight cancelled Had to fly out of different city Flight at new departure city was delayed 3 hours causing us to miss connecting flights. By the time we did make it to Prague our luggage did not. Had to wait day and a half for luggage to be delivered. Customer service was not good. Agents did not arrive at gate until 5-10 minutes before boarding

Flight itself excellent, but delayed so missed connection & got to destination 2 hrs later

It was better than excellent. The staff in Mason City were great. The young woman that pushed my wheelchair did more than could be expected of her. She came from India 17 years ago. I don't remember her name.

Boarding was organized. Old plane. Seat fairly comfortable. Business Class much too large so you don’t receive as much attention as you should considering what you pay for the seat.

Very rough getting into denver. my kid threw up it was so rough.

Liked that we left on time for each flight. Snacks not the best, but we're okay.

More water distribution throughout flight. Food quality poor and hot items delivered not hot on both attempts. Not United Standards

Air conditioning in the plane wasn’t working at boarding, this resulted in a delayed departure whilst they addressed the situation. The cabin was uncomfortably hot.

I had requested wheelchair assistance prior to flight. The airport staff had no record of it. It was not provided at Cedar Rapids which was a small airport, so I managed on my own. At O'Hare airport the same thing happened. The staff told me they had no record of my request for a wheel chair. But they finally provided it after a delay when I insisted that I needed it.

The flight attendant on my side of business class seemed like a novice and did not provide good service. Otherwise the flight was good and the entertainment system was very good. No free WiFi.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

Airport in MXP is crazy. Get there at least 2 hours before flight.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

I had a first class lie flat seat which broke within 20 minutes of takeoff. I had to sit at an uncomfortable position for 9 hours, and the crew was terribly inconsiderate. I ate in the aisle, didn't have any entertainment due to none of the electricity working on my chair.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.

More options for your flight from Des Moines to Italy

Complete your trip to Italy with a hotel stay or car rental