DSM - FLR

$424 Find Cheap Flights from Des Moines to Florence

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Florence departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Florence

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Florence, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Florence, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$1,035
Multiple Airlines
Thu 10/8Wed 10/14
DSM - FLR • 2 stops
Cheapest one-way
$424
American Airlines
Mon 10/5
DSM - FLR • 2 stops
Top airlines
Cheapest • from $1,051 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Florence. You'll need at least 2 connections.
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We hope you love your trip to Florence!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Florence (DSM-FLR)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Florence that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Florence

Thu, Oct 8 - Wed, Oct 14
Multiple Airlines Logo
9:37 am - 11:30 am
DSM
-
FLR
18h 53m
2 stops
Multiple Airlines Logo
7:05 am - 8:11 pm
FLR
-
DSM
20h 06m
2 stops
$1,035Multiple Airlines
Thu, Oct 22 - Fri, Oct 30
Lufthansa Logo
1:05 pm - 12:40 pm
DSM
-
FLR
16h 35m
2 stops
Lufthansa Logo
1:15 pm - 11:01 pm
FLR
-
DSM
15h 46m
2 stops
$1,051Lufthansa
Thu, Oct 22 - Fri, Oct 30
United Airlines Logo
8:00 am - 4:35 pm
DSM
-
FLR
25h 35m
3 stops
United Airlines Logo
1:15 pm - 11:01 pm
FLR
-
DSM
15h 46m
2 stops
$1,075United Airlines
Sun, Jul 5 - Fri, Jul 17
United Airlines Logo
1:40 pm - 12:40 pm
DSM
-
FLR
16h 00m
2 stops
United Airlines Logo
8:15 am - 12:45 am
FLR
-
DSM
23h 30m
2 stops
$1,103United Airlines
Sun, Jul 5 - Fri, Jul 17
United Airlines Logo
6:00 am - 2:10 pm
DSM
-
FLR
25h 10m
3 stops
United Airlines Logo
8:15 am - 11:16 pm
FLR
-
DSM
22h 01m
2 stops
$1,104United Airlines
Sun, Oct 4 - Sat, Oct 10
United Airlines Logo
6:15 am - 12:40 pm
DSM
-
FLR
23h 25m
2 stops
United Airlines Logo
1:40 pm - 9:17 pm
FLR
-
DSM
38h 37m
2 stops
$1,105United Airlines
Sun, Aug 16 - Thu, Aug 20
Scandinavian Airlines Logo
2:15 pm - 7:05 pm
DSM
-
FLR
21h 50m
2 stops
Scandinavian Airlines Logo
12:20 pm - 10:26 pm
FLR
-
DSM
41h 06m
2 stops
$1,205Scandinavian Airlines
Mon, Jul 6 - Sat, Jul 18
Lufthansa Logo
6:55 pm - 10:20 pm
DSM
-
FLR
20h 25m
2 stops
Lufthansa Logo
1:20 pm - 9:40 pm
FLR
-
DSM
15h 20m
2 stops
$1,214Lufthansa
Sun, Jul 5 - Sat, Jul 18
Multiple Airlines Logo
7:13 pm - 10:20 pm
DSM
-
FLR
20h 07m
2 stops
Multiple Airlines Logo
6:45 am - 5:43 pm
FLR
-
DSM
17h 58m
2 stops
$1,228Multiple Airlines
Mon, Jul 6 - Sat, Jul 18
United Airlines Logo
6:00 am - 12:40 pm
DSM
-
FLR
23h 40m
3 stops
United Airlines Logo
1:20 pm - 9:40 pm
FLR
-
DSM
15h 20m
2 stops
$1,231United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Florence flights

Get data-powered insights and trends into flights from Des Moines to Florence to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Florence?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Florence were found on Lufthansa ($1,051) and United Airlines ($1,075).

Good to know

Cheapest flight$424
Flight from Des Moines to Florence

When to book flights from Des Moines to Florence

Are your dates flexible? Find out the best times to travel from Des Moines to Florence based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Florence

  • What is the cheapest flight from Des Moines to Florence?

    In the last 3 days, the lowest price for a flight from Des Moines to Florence was $424 for a one-way ticket and $1,035 for a round-trip.

  • Do I need a passport to fly between Des Moines and Florence?

    A passport is required to fly from Des Moines to Florence.

  • Which airports will I be using when flying from Des Moines to Florence?

    Des Moines and Florence are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Florence Peretola.

  • Which aircraft models fly most regularly from Des Moines to Florence?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Florence?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Des Moines and Florence, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Florence, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Florence are Delta and United Airlines. With an average price for the route of $1,287 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $1,195 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Florence?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Florence.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Florence?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Florence from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Florence?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Florence with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and FLR can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Florence?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Florence from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Florence

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Florence. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Florence? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8463 reviews
7.8Entertainment
7.9Comfort
8.5Crew
7.2Food
8.1Boarding
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

Some crew were unfriendly or in some cases just straight up rude.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

Food was surprisingly delicious. Space in the seat is horrible when the seating front is reclined. Movie offerings were terrible. Crew was friendly and helpful.

Everything you need to know for your flight from Des Moines to Florence

Information on your arrival and departure airports