Which airports can I use when flying from Des Moines to Florence?

Flights from Des Moines to Florence usually depart from Des Moines (DSM) and arrive at Florence Peretola (FLR).

What cabin classes can I book on flights from Des Moines to Florence?

Only Economy Class is available on flights from Des Moines to Florence.

Can I save money by using flexible dates for flights from Des Moines to Florence?

Yes. Being flexible with your travel dates can save you up to 62% on the Des Moines to Florence route. Wednesday is the cheapest departure day at $526 round-trip on average, while Sunday is the most expensive at $1,360, a difference of $834. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

What popular places can I visit in Florence?

Some of the most popular sights in Florence are Cattedrale di Santa Maria del Fiore, Piazza del Duomo and Tempio maggiore israelitico di Firenze. These are among the most viewed places in Florence on KAYAK.

Do I need a passport to fly from Des Moines to Florence?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Des Moines to Florence changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $719 to $3,630. That means the highest observed fare was about 5x higher than the lowest one.

How are flight prices from Des Moines to Florence looking right now?

One-way fares from Des Moines to Florence are currently higher than usual. Average one-way flight prices are about $788, which is 45% above the typical average for this route.

What is the time difference between Des Moines and Florence?

Florence is 7 hours ahead of Des Moines (Central European Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Florence Peretola Airport (FLR)?

Florence Peretola Airport (FLR) hosts 5 major car rental companies, with daily rates starting from around $3 for economy cars. Top options include: • SURPRICE CAR RENTAL • NOLEGGIARE • Europcar • Ecovia • DRIVALIA

How much should I expect to pay for a Des Moines to Florence flight?

Round-trip flights from Des Moines to Florence range from $821 to $1,287, with an average of $1,124 over the past 12 months. Anything below $821 counts as a good deal.

What is the cheapest airline to fly from Des Moines to Florence?

Lufthansa ($719) and United Airlines ($724) are the cheapest airlines to fly round-trip from Des Moines to Florence according to KAYAK data over the last 5 days.

$719 CHEAP FLIGHTS from Des Moines to Florence (DSM - FLR)

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Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$719

Typical prices: $821-$1,287

Lufthansa

Tue 10/30Tue 11/6

DSM - FLR • 2 stops

Cheapest one-way

$725

Typical prices: $532-$802

SWISS

Tue 10/9

DSM - FLR • 2 stops

When to travel

February

Cheapest • 55% price drop

February

Most popular

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Flight Deals

Cheap Flights from Des Moines to Florence (DSM-FLR)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from Des Moines to Florence

Fri, Oct 30 - Fri, Nov 6

6:45 pm - 4:20 pmDSM Des Moines-FLR Florence Peretola

15h 35m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:30 am - 5:28 pmFLR Florence Peretola-DSM Des Moines

17h 58m2 stops Frankfurt am Main Chicago O'Hare Intl

$719Lufthansa

Sun, Mar 7 - Tue, Mar 16

9:09 am - 4:20 pmDSM Des Moines-FLR Florence Peretola

24h 11m2 stops Denver Intl Munich Franz Josef Strauss

9:50 am - 9:17 pmFLR Florence Peretola-DSM Des Moines

17h 27m2 stops Zurich Chicago O'Hare Intl

$724United Airlines

Sun, Mar 7 - Tue, Mar 16

6:15 am - 11:05 amDSM Des Moines-FLR Florence Peretola

21h 50m3 stops Chicago O'Hare Intl Newark Brussels Bruxelles-National

9:50 am - 9:17 pmFLR Florence Peretola-DSM Des Moines

17h 27m2 stops Zurich Chicago O'Hare Intl

$725United Airlines

Fri, Jan 15 - Fri, Jan 22

8:00 am - 1:50 pmDSM Des Moines-FLR Florence Peretola

22h 50m2 stops Chicago O'Hare Intl Zurich

9:50 am - 11:16 pmFLR Florence Peretola-DSM Des Moines

20h 26m2 stops Zurich Chicago O'Hare Intl

$729United Airlines

Sun, Feb 7 - Fri, Feb 12

1:02 pm - 4:20 pmDSM Des Moines-FLR Florence Peretola

20h 18m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

1:10 pm - 5:33 pmFLR Florence Peretola-DSM Des Moines

35h 23m2 stops Munich Franz Josef Strauss Chicago O'Hare Intl

$772Lufthansa

Mon, Feb 1 - Fri, Feb 5

3:25 pm - 1:50 pmDSM Des Moines-FLR Florence Peretola

15h 25m2 stops Chicago O'Hare Intl Zurich

9:50 am - 9:41 pmFLR Florence Peretola-DSM Des Moines

18h 51m2 stops Zurich Chicago O'Hare Intl

$786United Airlines

Mon, Feb 1 - Fri, Feb 5

9:37 am - 12:30 pmDSM Des Moines-FLR Florence Peretola

19h 53m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:30 am - 8:32 pmFLR Florence Peretola-DSM Des Moines

21h 02m2 stops Frankfurt am Main Denver Intl

$788United Airlines

Mon, Feb 1 - Fri, Feb 5

9:37 am - 12:30 pmDSM Des Moines-FLR Florence Peretola

19h 53m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:30 am - 8:10 pmFLR Florence Peretola-DSM Des Moines

20h 40m2 stops Frankfurt am Main Chicago O'Hare Intl

$788United Airlines

Sun, Feb 7 - Fri, Feb 12

8:00 am - 2:05 pmDSM Des Moines-FLR Florence Peretola

23h 05m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Zurich

6:30 am - 7:25 pmFLR Florence Peretola-DSM Des Moines

19h 55m2 stops Frankfurt am Main Chicago O'Hare Intl

$790United Airlines

Sun, Feb 7 - Fri, Feb 12

9:37 am - 9:40 amDSM Des Moines-FLR Florence Peretola

17h 03m3 stops Chicago O'Hare Intl Toronto Pearson Intl Frankfurt am Main

8:15 am - 9:17 pmFLR Florence Peretola-DSM Des Moines

20h 02m3 stops Munich Franz Josef Strauss Toronto Pearson Intl Chicago O'Hare Intl

$819Air Canada

Booking Insights

Price, demand and travel trends for Des Moines to Florence flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Florence with more confidence.

Prices

Airlines

How much is a round-trip flight from Des Moines to Florence?

Round-trip flights from Des Moines to Florence start at $719. Prices are below average for this route right now, with typical round-trip fares ranging from $821 to $1,287. The lowest price found in the past 5 days was $719 on Lufthansa.

Find deals

Low season	June
High season	February
Cheapest flight	$725

Best time to beat the crowds with an average 19% drop in price.

Most popular time to fly and prices are also 55% lower on average.

Flight from Des Moines to Florence

When to book flights from Des Moines to Florence

Are your dates flexible? Find out the best times to travel from Des Moines to Florence based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Des Moines to Florence?
Flights from Des Moines to Florence usually depart from Des Moines (DSM) and arrive at Florence Peretola (FLR).
What cabin classes can I book on flights from Des Moines to Florence?
Only Economy Class is available on flights from Des Moines to Florence.
Can I save money by using flexible dates for flights from Des Moines to Florence?
Yes. Being flexible with your travel dates can save you up to 62% on the Des Moines to Florence route. Wednesday is the cheapest departure day at $526 round-trip on average, while Sunday is the most expensive at $1,360, a difference of $834. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
What popular places can I visit in Florence?
Some of the most popular sights in Florence are Cattedrale di Santa Maria del Fiore, Piazza del Duomo and Tempio maggiore israelitico di Firenze. These are among the most viewed places in Florence on KAYAK.
Do I need a passport to fly from Des Moines to Florence?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
Have flight prices from Des Moines to Florence changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $719 to $3,630. That means the highest observed fare was about 5x higher than the lowest one.
How are flight prices from Des Moines to Florence looking right now?
One-way fares from Des Moines to Florence are currently higher than usual. Average one-way flight prices are about $788, which is 45% above the typical average for this route.
What is the time difference between Des Moines and Florence?
Florence is 7 hours ahead of Des Moines (Central European Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Florence Peretola Airport (FLR)?
Florence Peretola Airport (FLR) hosts 5 major car rental companies, with daily rates starting from around $3 for economy cars. Top options include:
• SURPRICE CAR RENTAL
• NOLEGGIARE
• Europcar
• Ecovia
• DRIVALIA
How much should I expect to pay for a Des Moines to Florence flight?
Round-trip flights from Des Moines to Florence range from $821 to $1,287, with an average of $1,124 over the past 12 months. Anything below $821 counts as a good deal.

If your dates can be flexible, aim for a Wednesday departure instead of Sunday. On this route, Wednesday flights average $526 - about $834 less than Sunday (61% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to Florence trip for February. Fares historically average $502 round-trip in that month - typically $941 less than the most expensive month, which is December (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Florence Peretola Airport.
- Wyndham Garden Florence
- Novotel Firenze Nord Aeroporto
- B&B Hotel Firenze Novoli

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DSM - FLR

$719 Find Cheap Flights from Des Moines to Florence - Compare and Save

Everything you should know

Cheap Flights from Des Moines to Florence (DSM-FLR)

Recent round-trip flight deals from Des Moines to Florence

Recent one-way flight deals from Des Moines to Florence

Price, demand and travel trends for Des Moines to Florence flights

How much is a round-trip flight from Des Moines to Florence?

What is the cheapest airline to fly from Des Moines to Florence?

Key details for Des Moines to Florence flights

Low season

High season

Cheapest flight

When to book flights from Des Moines to Florence

Your Des Moines to Florence flight questions, answered

Your guide to booking Des Moines to Florence flights

More options for your flight from Des Moines to Florence

Complete your trip to Florence with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Des Moines to Florence

Find direct flights to and from Des Moines and Florence

Flights from domestic origins to Florence

Flights to other popular destinations