$354 Find Cheap Flights from Des Moines to Saint Lucia - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Saint Lucia departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to Saint Lucia Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Saint Lucia that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Saint Lucia

Mon, Sep 21 - Thu, Oct 1
American Airlines Logo
1:09 pm - 2:02 pm
DSM
-
UVF
23h 53m
2 stops
American Airlines Logo
3:02 pm - 12:31 pm
UVF
-
DSM
22h 29m
2 stops
$733American Airlines
Mon, Sep 21 - Thu, Oct 1
American Airlines Logo
4:14 pm - 2:02 pm
DSM
-
UVF
20h 48m
2 stops
American Airlines Logo
3:02 pm - 1:59 pm
UVF
-
DSM
23h 57m
2 stops
$733American Airlines
Fri, Sep 11 - Fri, Sep 18
Delta Logo
5:45 am - 2:12 pm
DSM
-
UVF
7h 27m
1 stop
Delta Logo
3:32 pm - 9:38 am
UVF
-
DSM
19h 06m
2 stops
$733Delta
Wed, Dec 9 - Sun, Dec 13
American Airlines Logo
4:07 pm - 3:53 pm
DSM
-
UVF
21h 46m
2 stops
American Airlines Logo
4:53 pm - 1:19 pm
UVF
-
DSM
22h 26m
2 stops
$743American Airlines
Wed, Dec 9 - Sun, Dec 13
American Airlines Logo
4:07 pm - 3:02 pm
DSM
-
UVF
20h 55m
1 stop
American Airlines Logo
4:53 pm - 12:23 pm
UVF
-
DSM
21h 30m
2 stops
$754American Airlines
Sun, Jan 10 - Fri, Jan 15
American Airlines Logo
3:59 pm - 3:03 pm
DSM
-
UVF
21h 04m
2 stops
American Airlines Logo
4:05 pm - 8:54 am
UVF
-
DSM
18h 49m
2 stops
$759American Airlines
Sun, Sep 6 - Sun, Sep 13
Delta Logo
5:40 am - 2:14 pm
DSM
-
UVF
7h 34m
1 stop
Delta Logo
3:32 pm - 5:19 pm
UVF
-
DSM
26h 47m
2 stops
$773Delta
Sun, Nov 1 - Mon, Nov 30
Air Canada Logo
6:21 am - 4:40 pm
DSM
-
UVF
32h 19m
2 stops
Air Canada Logo
5:40 pm - 11:01 pm
UVF
-
DSM
31h 21m
2 stops
$1,157Air Canada
Thu, Nov 19 - Fri, Nov 27
Air Canada Logo
8:00 am - 4:40 pm
DSM
-
UVF
30h 40m
2 stops
Air Canada Logo
5:40 pm - 11:02 pm
UVF
-
DSM
31h 22m
2 stops
$1,182Air Canada
Thu, Nov 19 - Fri, Nov 27
Air Canada Logo
11:23 am - 4:40 pm
DSM
-
UVF
27h 17m
2 stops
Air Canada Logo
5:40 pm - 10:50 pm
UVF
-
DSM
31h 10m
2 stops
$1,245Air Canada
Booking Insights

KAYAK's insights & trends for Des Moines to Saint Lucia flights

Get data-powered insights and trends into flights from Des Moines to Saint Lucia to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Saint Lucia?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Des Moines to Saint Lucia were found on American Airlines ($733) and Delta ($773).

Good to know

Cheapest flight

$354
Flight from Des Moines to Castries

FAQs - booking Saint Lucia flights

  • How does KAYAK find such low prices on flights from Des Moines to Saint Lucia?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Saint Lucia.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Saint Lucia?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to Saint Lucia is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Saint Lucia?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to Saint Lucia with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Saint Lucia?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to Saint Lucia up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to Saint Lucia

 
Need help choosing which airline to fly with from Des Moines to Saint Lucia? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11839 reviews
7.5Boarding
7.9Crew
6.4Food
7.2Comfort
6.8Entertainment
Airline reviews

Horrible. No AC. No Air inside the plane. We had to deplane twice! It is late almost 5 hrs in total. I almost passed out and about to call 911. I asked the crew to be honest and open the door. The lady next to me was lay down in the floor due to heat and no air inside the plane. I got headaches, can’t wait the replacement flight about midnight Dallas time. I end it up rebook for next day flight and stay overnight using my own pocket in a hotel nearby due to headaches and can’t breath. I still have a headache this morning. Still not decided yes how to file this issue to AA and/or FAA.

2.0 MediocreKandar, Jul 2026
DFW - SFO
Read more American Airlines reviews

Horrible. No AC. No Air inside the plane. We had to deplane twice! It is late almost 5 hrs in total. I almost passed out and about to call 911. I asked the crew to be honest and open the door. The lady next to me was lay down in the floor due to heat and no air inside the plane. I got headaches, can’t wait the replacement flight about midnight Dallas time. I end it up rebook for next day flight and stay overnight using my own pocket in a hotel nearby due to headaches and can’t breath. I still have a headache this morning. Still not decided yes how to file this issue to AA and/or FAA.

They have overselled the ticket and kicked me out from boarding, All my Plans were collapsed and important network meeting missed.also I booked direct flight i have to go through an 1 stop and it was frustrated.

Flight was delayed for 5 hours in ten minute increments. Bizarre and frustrating

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

In flight connectivity (via T-Mobile) was often not working.

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.

Everything you need to know for your flight from Des Moines to Saint Lucia

Information on your arrival and departure airports