DSM - SAF

$367 Find Cheap Flights from Des Moines to Santa Fe - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$367
Typical prices: $346-$531
United Airlines
Wed 11/7Sun 11/11
DSM - SAF • 1 stop
When to travel
October
Cheapest • 24% price drop
May
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Denver Intl (DEN)
Cheapest • Avg $476 (round-trip)
Dallas/Fort Worth (DFW)
Shortest trip • 5h 11m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Des Moines to Santa Fe (DSM-SAF)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santa Fe

Sat, Nov 7 - Wed, Nov 11
United Airlines Logo
1:27 pm - 5:10 pmDSM  Des Moines-SAF Santa Fe
4h 43m1 stop Denver Intl
United Airlines Logo
5:55 pm - 11:42 pmSAF  Santa Fe-DSM Des Moines
4h 47m1 stop Denver Intl
$367United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
5:30 am - 9:45 amDSM  Des Moines-SAF Santa Fe
5h 15m1 stop Denver Intl
United Airlines Logo
5:55 pm - 11:42 pmSAF  Santa Fe-DSM Des Moines
4h 47m1 stop Denver Intl
$367United Airlines
Mon, Mar 1 - Sat, Mar 6
American Airlines Logo
5:06 am - 11:09 amDSM  Des Moines-SAF Santa Fe
7h 03m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
5:24 pm - 11:14 pmSAF  Santa Fe-DSM Des Moines
4h 50m1 stop Dallas/Fort Worth
$416American Airlines
Wed, Dec 30 - Mon, Jan 4
United Airlines Logo
9:00 am - 2:45 pmDSM  Des Moines-SAF Santa Fe
6h 45m1 stop Denver Intl
United Airlines Logo
5:46 pm - 11:59 pmSAF  Santa Fe-DSM Des Moines
5h 13m1 stop Denver Intl
$416United Airlines
Fri, Jan 1 - Wed, Jan 6
American Airlines Logo
5:05 am - 9:50 amDSM  Des Moines-SAF Santa Fe
5h 45m1 stop Dallas/Fort Worth
American Airlines Logo
7:39 am - 4:11 pmSAF  Santa Fe-DSM Des Moines
7h 32m1 stop Dallas/Fort Worth
$437American Airlines
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
5:30 am - 9:12 amDSM  Des Moines-SAF Santa Fe
4h 42m1 stop Denver Intl
United Airlines Logo
5:55 pm - 11:42 pmSAF  Santa Fe-DSM Des Moines
4h 47m1 stop Denver Intl
$437United Airlines
Sat, Feb 27 - Mon, Mar 8
United Airlines Logo
6:15 am - 11:31 amDSM  Des Moines-SAF Santa Fe
6h 16m1 stop Chicago O'Hare Intl
United Airlines Logo
6:01 pm - 11:39 pmSAF  Santa Fe-DSM Des Moines
4h 38m1 stop Denver Intl
$437United Airlines
Tue, Mar 2 - Tue, Mar 9
United Airlines Logo
6:15 am - 11:31 amDSM  Des Moines-SAF Santa Fe
6h 16m1 stop Chicago O'Hare Intl
United Airlines Logo
1:20 pm - 8:41 pmSAF  Santa Fe-DSM Des Moines
6h 21m1 stop Denver Intl
$437United Airlines
Sat, Feb 27 - Tue, Mar 9
United Airlines Logo
6:15 am - 11:31 amDSM  Des Moines-SAF Santa Fe
6h 16m1 stop Chicago O'Hare Intl
United Airlines Logo
3:10 pm - 8:41 pmSAF  Santa Fe-DSM Des Moines
4h 31m1 stop Denver Intl
$437United Airlines
Tue, Jan 26 - Sat, Jan 30
United Airlines Logo
9:00 am - 12:49 pmDSM  Des Moines-SAF Santa Fe
4h 49m1 stop Denver Intl
United Airlines Logo
10:45 am - 4:11 pmSAF  Santa Fe-DSM Des Moines
4h 26m1 stop Denver Intl
$437United Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Santa Fe flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Santa Fe?

Round-trip flights from Des Moines to Santa Fe typically range from $346 to $531. The lowest price found in the past 5 days was $367, on United Airlines.

What's the cheapest day of the week to fly from Des Moines to Santa Fe?

Based on deals KAYAK users found in the last 12 months, Sunday is the cheapest day of the week to fly from Des Moines to Santa Fe. It’s 23% cheaper than the average day, while Tuesday is the most expensive, with prices 51% higher.

Find deals

Key details for Des Moines to Santa Fe flights

Low season

January

Cheapest flight

$367
Beat the crowds with an average 65% drop in travelers.
The most popular month to fly with an average 52% increase in travelers.
Round-trip flight from Des Moines to Santa Fe

When to book flights from Des Moines to Santa Fe

Are your dates flexible? Find out the best times to travel from Des Moines to Santa Fe based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Santa Fe flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Santa Fe?

    Only Economy Class is available on flights from Des Moines to Santa Fe.

  • How long is a flight from Des Moines to Santa Fe?

    There are currently no nonstop flights available from Des Moines to Santa Fe. Flights with 1 layover take between 4h 49m and 5h 11m in total, depending on the connection.

  • Do I need a passport to fly from Des Moines to Santa Fe?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Des Moines to Santa Fe flight?

    Round-trip flights from Des Moines to Santa Fe range from $346 to $531, with an average of $429 over the past 12 months. Anything below $346 counts as a good deal.

  • Have flight prices from Des Moines to Santa Fe changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $367 to $1,249. That means the highest observed fare was about 3x higher than the lowest one.

  • What car rental options are available at Santa Fe Airport (SAF)?

    Santa Fe Airport (SAF) hosts 5 major car rental companies, with daily rates starting from around $28 for economy cars. Top options include:

    • Hertz
    • Enterprise Rent-A-Car
    • Avis
    • Budget
    • National

  • Which airports can I use when flying from Des Moines to Santa Fe?

    Flights from Des Moines to Santa Fe usually depart from Des Moines (DSM) and arrive at Santa Fe (SAF).

  • Which airports do connecting flights from Des Moines to Santa Fe pass through?

    Connecting flights from Des Moines to Santa Fe most commonly pass through:

    • Denver Intl (DEN) - 92% of one-stop connections
    • Dallas/Fort Worth (DFW) - 8% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Santa Fe?

    Yes. Flexible dates can save you up to 49% on flights from Des Moines to Santa Fe. Sunday is the cheapest departure day at $334 round-trip on average, while Tuesday is the most expensive at $652, a difference of $318.

    Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How much time can I save by choosing a different layover airport from Des Moines to Santa Fe?

    Flying via Denver Intl (DEN) gives the shortest average 1-stop total travel time at 4h 49m, compared with 5h 11m via Dallas/Fort Worth (DFW).

  • What is the time difference between Des Moines and Santa Fe?

    Santa Fe is 1 hour behind Des Moines (Mountain Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Des Moines to Santa Fe flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Sunday departure and avoid flying on Tuesday. On this route, Sunday flights average $334, about $318 less than Tuesday fares (49% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Santa Fe trip for October. Fares historically average $324 round-trip in that month - typically $480 less than the most expensive month, which is December (based on the last 12 months).

More options for your flight from Des Moines to Santa Fe

Complete your trip to Santa Fe with a hotel stay or car rental

Car rentals in Santa Fe
Hotels in Santa Fe
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