DSM - SAF

$274 Find Cheap Flights from Des Moines to Santa Fe

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santa Fe departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Fe

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santa Fe, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santa Fe, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$324
Typical prices: $463-$383
American Airlines
Fri 5/29Wed 6/3
DSM - SAF • 1 stop
Cheapest one-way
$274
American Airlines
Fri 7/17
DSM - SAF • 1 stop
Top airlines
Cheapest • from $324 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santa Fe. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $525 (round-trip)
Shortest trip • 4h 46m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Fe!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santa Fe (DSM-SAF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santa Fe that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santa Fe

Fri, May 29 - Wed, Jun 3
American Airlines Logo
4:48 pm - 9:52 pm
DSM
-
SAF
6h 04m
1 stop
American Airlines Logo
5:13 pm - 11:57 pm
SAF
-
DSM
5h 44m
1 stop
$324American Airlines
Thu, May 7 - Mon, May 11
United Airlines Logo
5:30 am - 9:24 am
DSM
-
SAF
4h 54m
1 stop
United Airlines Logo
5:49 pm - 11:44 pm
SAF
-
DSM
4h 55m
1 stop
$334United Airlines
Sat, May 9 - Wed, May 13
American Airlines Logo
3:20 pm - 9:07 pm
DSM
-
SAF
6h 47m
1 stop
American Airlines Logo
11:56 am - 11:59 pm
SAF
-
DSM
11h 03m
2 stops
$344American Airlines
Sat, May 9 - Wed, May 13
American Airlines Logo
5:00 am - 2:55 pm
DSM
-
SAF
10h 55m
2 stops
American Airlines Logo
11:56 am - 11:59 pm
SAF
-
DSM
11h 03m
2 stops
$349American Airlines
Thu, Jun 25 - Mon, Jun 29
United Airlines Logo
5:50 am - 9:44 am
DSM
-
SAF
4h 54m
1 stop
United Airlines Logo
6:00 pm - 11:44 pm
SAF
-
DSM
4h 44m
1 stop
$353United Airlines
Thu, Jun 25 - Mon, Jun 29
United Airlines Logo
5:50 am - 9:44 am
DSM
-
SAF
4h 54m
1 stop
United Airlines Logo
6:00 pm - 11:44 pm
SAF
-
DSM
4h 44m
1 stop
$362United Airlines
Mon, May 25 - Mon, Jun 1
United Airlines Logo
5:50 am - 9:44 am
DSM
-
SAF
4h 54m
1 stop
United Airlines Logo
6:00 pm - 11:44 pm
SAF
-
DSM
4h 44m
1 stop
$363United Airlines
Wed, May 27 - Sat, May 30
American Airlines Logo
4:48 pm - 9:52 pm
DSM
-
SAF
6h 04m
1 stop
American Airlines Logo
7:30 am - 4:03 pm
SAF
-
DSM
7h 33m
1 stop
$364American Airlines
Wed, May 6 - Sat, May 9
American Airlines Logo
5:00 am - 10:07 am
DSM
-
SAF
6h 07m
1 stop
American Airlines Logo
4:09 pm - 11:59 pm
SAF
-
DSM
6h 50m
1 stop
$374American Airlines
Wed, May 6 - Sat, May 9
American Airlines Logo
5:00 am - 12:06 pm
DSM
-
SAF
8h 06m
1 stop
American Airlines Logo
11:56 am - 11:59 pm
SAF
-
DSM
11h 03m
2 stops
$384American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santa Fe flights

Get data-powered insights and trends into flights from Des Moines to Santa Fe to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Des Moines to Santa Fe?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Des Moines to Santa Fe departing in May.

Good to know

Low seasonOctober
Cheapest flight$274
Best time to beat the crowds with an average 30% drop in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Des Moines to Santa Fe

When to book flights from Des Moines to Santa Fe

Are your dates flexible? Find out the best times to travel from Des Moines to Santa Fe based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santa Fe

  • What is the cheapest flight from Des Moines to Santa Fe?

    In the last 3 days, the lowest price for a flight from Des Moines to Santa Fe was $274 for a one-way ticket and $324 for a round-trip.

  • Do I need a passport to fly between Des Moines and Santa Fe?

    A passport is not required to fly from Des Moines to Santa Fe.

  • Which airports will I be using when flying from Des Moines to Santa Fe?

    Des Moines and Santa Fe are both served by 1 main airport. You will leave Des Moines from Des Moines and will be arriving at Santa Fe.

  • Which aircraft models fly most regularly from Des Moines to Santa Fe?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santa Fe?

    oneworld, and Star Alliance are the airline alliances operating flights between Des Moines and Santa Fe, with oneworld being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Des Moines to Santa Fe?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santa Fe.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santa Fe?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Fe from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santa Fe?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Fe with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SAF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santa Fe?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Fe from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santa Fe

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santa Fe. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santa Fe? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9650 reviews
7.3Comfort
8.1Crew
7.7Boarding
7.1Entertainment
6.6Food
Airline reviews

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

6.0 GoodGuido, Apr 2026
BOI - ORD
Read more United Airlines reviews

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

They told us yesterday APR21st that they were cleaning the plane and we got delayed. After that they said they didn't had any crew for the flight so they cancelled the flight till next day.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight crew on this leg of my trip was very friendly and pleasant. Every one of them was humorous, as well as helpful and accommodating. This group was BY FAR the best crew I’ve flown with. They deserve kudos.

boarded early to only find out that flight would sit at gate for 45 min to an hour. Landed in chicago and sat on runway for over an hour before got to gate. Total delay was extensive for a 45 min flight door to door.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

The flight was significantly delayed. The inbound flight from EWR was delayed departing because of mechanical problems. My original departure from CLT was 5:28 pm but due to the delay of the inbound flight, after arrival, deplaning, cleaning, boarding, we did not push back from the gate until 9:00 pm. Once in the air, the flight was smooth and what was originally supposed to be an arrival in ORD at 7:30 pm local time turned out to be 9:35 pm.

My bags were misplaced!!! Im in a foreign country with no bags

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

On time departure and early arrival. Flight attendant very nice.

As we approached Denver, we encountered quite a bit of turbulence. I know this can sometimes be the case as I frequently fly this route but not on American. My gripe: Usually a pilot or co-pilot alerts passengers to the possibility of turbulance ahead of time. This did not occur nor did he communiucate during what was a pretty rough ride.

The staff was nice. I appreciated that I was able to take an earlier flight, even though it was last minute. The boarding process felt rather chaotic.

Overall a good experience, however Wifi was not working on the flight.

Everything you need to know for your flight from Des Moines to Santa Fe

Information on your arrival and departure airports