DSM - SAF

$317 Find Cheap Flights from Des Moines to Santa Fe - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Everything you should know

Cheapest round-trip
$317
Typical prices: $346-$542
American Airlines
Wed 10/24Tue 10/30
DSM - SAF • 1 stop
When to travel
August
Cheapest • 29% price drop
May
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Denver Intl (DEN)
Cheapest • Avg $466 (round-trip)
Dallas/Fort Worth (DFW)
Shortest trip • 5h 11m (one-way)
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Fe!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santa Fe (DSM-SAF)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santa Fe

Sat, Oct 24 - Fri, Oct 30
American Airlines Logo
5:06 am - 11:26 amDSM  Des Moines-SAF Santa Fe
7h 20m1 stop Phoenix Sky Harbor Intl
American Airlines Logo
5:26 pm - 11:07 pmSAF  Santa Fe-DSM Des Moines
4h 41m1 stop Dallas/Fort Worth
$317American Airlines
Sun, Dec 6 - Sun, Dec 13
American Airlines Logo
3:31 pm - 7:44 pmDSM  Des Moines-SAF Santa Fe
5h 13m1 stop Dallas/Fort Worth
American Airlines Logo
5:21 pm - 11:05 pmSAF  Santa Fe-DSM Des Moines
4h 44m1 stop Dallas/Fort Worth
$317American Airlines
Sat, Oct 24 - Tue, Oct 27
American Airlines Logo
4:12 pm - 9:55 pmDSM  Des Moines-SAF Santa Fe
6h 43m1 stop Dallas/Fort Worth
American Airlines Logo
8:05 am - 3:11 pmSAF  Santa Fe-DSM Des Moines
6h 06m1 stop Dallas/Fort Worth
$317American Airlines
Wed, Nov 11 - Sat, Nov 14
United Airlines Logo
5:30 am - 9:12 amDSM  Des Moines-SAF Santa Fe
4h 42m1 stop Denver Intl
United Airlines Logo
5:55 pm - 11:42 pmSAF  Santa Fe-DSM Des Moines
4h 47m1 stop Denver Intl
$397United Airlines
Wed, Nov 11 - Wed, Nov 18
United Airlines Logo
5:30 am - 9:12 amDSM  Des Moines-SAF Santa Fe
4h 42m1 stop Denver Intl
United Airlines Logo
5:55 pm - 11:42 pmSAF  Santa Fe-DSM Des Moines
4h 47m1 stop Denver Intl
$397United Airlines
Tue, Nov 10 - Tue, Nov 17
American Airlines Logo
3:31 pm - 7:44 pmDSM  Des Moines-SAF Santa Fe
5h 13m1 stop Dallas/Fort Worth
American Airlines Logo
10:09 am - 5:46 pmSAF  Santa Fe-DSM Des Moines
6h 37m1 stop Dallas/Fort Worth
$397American Airlines
Sat, Nov 14 - Thu, Nov 19
American Airlines Logo
3:31 pm - 9:56 pmDSM  Des Moines-SAF Santa Fe
7h 25m1 stop Dallas/Fort Worth
American Airlines Logo
10:12 am - 6:27 pmSAF  Santa Fe-DSM Des Moines
7h 15m1 stop Dallas/Fort Worth
$397American Airlines
Fri, Nov 13 - Thu, Nov 19
American Airlines Logo
3:31 pm - 9:56 pmDSM  Des Moines-SAF Santa Fe
7h 25m1 stop Dallas/Fort Worth
American Airlines Logo
10:12 am - 6:27 pmSAF  Santa Fe-DSM Des Moines
7h 15m1 stop Dallas/Fort Worth
$397American Airlines
Sat, Nov 14 - Tue, Nov 17
American Airlines Logo
3:31 pm - 9:56 pmDSM  Des Moines-SAF Santa Fe
7h 25m1 stop Dallas/Fort Worth
American Airlines Logo
12:21 pm - 8:18 pmSAF  Santa Fe-DSM Des Moines
6h 57m1 stop Phoenix Sky Harbor Intl
$397American Airlines
Wed, Nov 11 - Tue, Nov 17
American Airlines Logo
7:23 am - 12:39 pmDSM  Des Moines-SAF Santa Fe
6h 16m1 stop Chicago O'Hare Intl
American Airlines Logo
8:00 am - 2:39 pmSAF  Santa Fe-DSM Des Moines
5h 39m1 stop Dallas/Fort Worth
$397American Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Santa Fe flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Santa Fe with more confidence.

How much is a round-trip flight from Des Moines to Santa Fe?

Round-trip flights from Des Moines to Santa Fe start at $317. Prices are below average for this route right now, with typical round-trip fares ranging from $346 to $542. The lowest price found in the past 5 days was $317 on American Airlines.

What's the cheapest day of the week to fly from Des Moines to Santa Fe?

Sunday is the cheapest day of the week to fly from Des Moines to Santa Fe, it is 23% cheaper than the average day. Monday is the most expensive day with flight prices 12% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Key details for Des Moines to Santa Fe flights

Low season

January

Cheapest flight

$317
Most popular time to fly with an average 24% increase in price.
Flight from Des Moines to Santa Fe

When to book flights from Des Moines to Santa Fe

Are your dates flexible? Find out the best times to travel from Des Moines to Santa Fe based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Santa Fe flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Des Moines to Santa Fe?

    Flights from Des Moines to Santa Fe usually depart from Des Moines (DSM) and arrive at Santa Fe (SAF).

  • What cabin classes can I book on flights from Des Moines to Santa Fe?

    Only Economy Class is available on flights from Des Moines to Santa Fe.

  • Which airports do connecting flights from Des Moines to Santa Fe pass through?

    Connecting flights from Des Moines to Santa Fe most commonly pass through:

    • Denver Intl (DEN) - 92% of one-stop connections
    • Dallas/Fort Worth (DFW) - 8% of one-stop connections
    Together, these airports account for 100% of one-stop bookings on this route.

  • Can I save money by using flexible dates for flights from Des Moines to Santa Fe?

    On the Des Moines to Santa Fe route, being flexible with your departure day can save you up to 31%. Sunday is the cheapest day at $334 round-trip on average, while Monday is the most expensive at $482: a $148 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

  • How long is a flight from Des Moines to Santa Fe?

    There are currently no nonstop flights available from Des Moines to Santa Fe. Flights with 1 layover take between 4h 58m and 5h 11m in total, depending on the connection.

  • Do I need a passport to fly from Des Moines to Santa Fe?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Des Moines to Santa Fe changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $317 to $1,263. That means the highest observed fare was about 4x higher than the lowest one.

  • How much time can I save by choosing a different layover airport from Des Moines to Santa Fe?

    Flying via Denver Intl (DEN) gives the shortest average 1-stop total travel time at 4h 58m, compared with 5h 11m via Dallas/Fort Worth (DFW).

  • What is the time difference between Des Moines and Santa Fe?

    Santa Fe is 1 hour behind Des Moines (Mountain Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Santa Fe Airport (SAF)?

    Santa Fe Airport (SAF) hosts 5 major car rental companies, with daily rates starting from around $27 for economy cars. Top options include:
    · Hertz
    · Enterprise Rent-A-Car
    · Avis
    · Budget
    · National

  • How much should I expect to pay for a Des Moines to Santa Fe flight?

    Round-trip flights from Des Moines to Santa Fe range from $346 to $542, with an average of $429 over the past 12 months. Anything below $346 counts as a good deal.

Your guide to booking Des Moines to Santa Fe flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Sunday departure instead of Monday. On this route, Sunday flights average $334 - about $148 less than Monday (31% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Santa Fe trip for August. Fares historically average $304 round-trip in that month - typically $504 less than the most expensive month, which is November (based on the last 12 months).

More options for your flight from Des Moines to Santa Fe

Complete your trip to Santa Fe with a hotel stay or car rental

Car rentals in Santa Fe
Hotels in Santa Fe
Vacations in Santa Fe