DSM - SDQ

$238 Find Cheap Flights from Des Moines to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$547
Multiple Airlines
Thu 4/9Sat 4/18
DSM - SDQ • 1 stop
Cheapest one-way
$238
Multiple Airlines
Mon 5/4
DSM - SDQ • 3 stops
Top airlines
Delta
Cheapest • from $613 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Thu, Apr 9 - Sat, Apr 18
Multiple Airlines Logo
7:00 am - 2:40 am
DSM
-
SDQ
18h 40m
1 stop
Multiple Airlines Logo
3:35 pm - 1:46 pm
SDQ
-
DSM
23h 11m
2 stops
$547Multiple Airlines
Thu, Apr 9 - Sat, Apr 18
Multiple Airlines Logo
7:00 am - 2:40 am
DSM
-
SDQ
18h 40m
1 stop
Multiple Airlines Logo
3:44 pm - 4:00 pm
SDQ
-
DSM
25h 16m
1 stop
$571Multiple Airlines
Thu, Mar 26 - Sat, Mar 28
Multiple Airlines Logo
6:00 am - 1:38 am
DSM
-
SDQ
18h 38m
1 stop
Multiple Airlines Logo
2:52 am - 1:59 pm
SDQ
-
DSM
12h 07m
1 stop
$579Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Delta Logo
5:35 am - 1:12 pm
DSM
-
SDQ
6h 37m
1 stop
Delta Logo
8:25 pm - 10:48 am
SDQ
-
DSM
15h 23m
2 stops
$613Delta
Thu, Mar 26 - Sat, Mar 28
Multiple Airlines Logo
6:00 am - 2:40 am
DSM
-
SDQ
19h 40m
2 stops
Multiple Airlines Logo
2:52 am - 1:59 pm
SDQ
-
DSM
12h 07m
1 stop
$614Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
7:44 pm - 1:00 pm
DSM
-
SDQ
16h 16m
2 stops
American Airlines Logo
5:50 pm - 10:34 am
SDQ
-
DSM
17h 44m
2 stops
$623American Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
6:40 am - 10:53 pm
DSM
-
SDQ
15h 13m
2 stops
American Airlines Logo
10:20 am - 11:49 pm
SDQ
-
DSM
14h 29m
2 stops
$628American Airlines
Fri, May 22 - Mon, May 25
Multiple Airlines Logo
3:57 pm - 11:17 am
DSM
-
SDQ
18h 20m
1 stop
Multiple Airlines Logo
6:10 am - 2:00 pm
SDQ
-
DSM
8h 50m
1 stop
$629Multiple Airlines
Wed, Apr 1 - Wed, Apr 8
American Airlines Logo
6:40 am - 10:53 pm
DSM
-
SDQ
15h 13m
2 stops
American Airlines Logo
2:25 pm - 11:49 pm
SDQ
-
DSM
10h 24m
2 stops
$630American Airlines
Mon, Mar 30 - Mon, Apr 6
American Airlines Logo
6:00 am - 10:53 pm
DSM
-
SDQ
15h 53m
1 stop
American Airlines Logo
4:03 pm - 11:56 pm
SDQ
-
DSM
8h 53m
1 stop
$634American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santo Domingo flights

Get data-powered insights and trends into flights from Des Moines to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Santo Domingo were found on Delta ($613) and American Airlines ($623).

Good to know

Cheapest flight$238
Most popular time to fly and prices are also 1% lower on average.
Flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santo Domingo

  • What is the cheapest flight from Des Moines to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Des Moines to Santo Domingo was $238 for a one-way ticket and $547 for a round-trip.

  • Do I need a passport to fly between Des Moines and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santo Domingo?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Des Moines to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santo Domingo?

    oneworld, and SkyTeam are the airline alliances operating flights between Des Moines and Santo Domingo, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santo Domingo are Delta and American Airlines. With an average price for the route of $574 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $684 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Des Moines to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8206 reviews
8.1Boarding
8.5Crew
7.2Food
7.9Comfort
7.8Entertainment
Airline reviews

Delta flights recently are always delayed AND at jfk tney get the gates further away (need To walk 20’ to get to them/all the way at the end of the terminal). Not sure whats happening but price doesnt match experience!

2.0 MediocreDimitrios, Feb 2026
JFK - DFW
Read more Delta reviews

Delta flights recently are always delayed AND at jfk tney get the gates further away (need To walk 20’ to get to them/all the way at the end of the terminal). Not sure whats happening but price doesnt match experience!

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Good experience and the flight landed early. There was no food I had or entertainment.

Flight was delayed and no reasons provided. After the passengers were boarded, the crew made announcement that the captain has jot arrived and he would take another 15 mins. All passengers patiently sat until the captain came and started. Terrible experience!

Flight was delayed. No information on why it was delayed. After we boarded the flight, , the crew made announcement that the captain hs not arrived and he will take 15 mins more to arrive. Passengers were just sitting patiently for the captain to arrive and start, Terrible experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

Smallest leg room I've ever had on a plane.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

The flight was fine. It's the satellite terminal that supports American eagle flights is what sucks. There is only one food option and everything there is way overpriced. I mean I know it's airport pricing, but it's even crazier than that. I bought a sandwich in a plastic container for $18.

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

The smell from the bathroom kept wafting through the cabin. It made people sick.

The flight was really crowded. Flight attendants were just ok.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Didn't get a seat assignment until the last minute even though i picked a seat.

American has been able to implement an algorithm that makes it possible for nearly every one of my evening flights to be late. Congratulations!

I was on a small regional flight from Detroit to Philadelphia. When we landed the outside cruise needed to turn something off with the engine, which took quite a long time. Then, when they allowed us to get off the plane it was outside. They took their time, unloading all the luggage and waited till they unloaded all the luggage before they brought it over to us. It was 9 o’clock at night freezing cold out, and there was no proactive hustle to try to get people their luggage. It was really one of the worst experiences I think I’ve ever had with American until a manager came over. I don’t think they were going to even consider pulling the luggage over to the people that had been waiting outside for at least 10 minutes in the freezing cold.

The flight was fine, once we got underway. It was more than hour delayed

Beverage service was not good. Also just one service in 5 hr 30 min flight. No ask fir water ir anything beside one time beverage service.

Everything you need to know for your flight from Des Moines to Santo Domingo

Information on your arrival and departure airports