DSM - SDQ

$654 Find Cheap Flights from Des Moines to Santo Domingo

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$654
American Airlines
Tue 7/14Tue 7/21
DSM - SDQ • 2 stops
Top airlines
Cheapest • from $654 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $712 (round-trip)
Shortest trip • 6h 47m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
8:50 pm - 3:24 pm
DSM
-
SDQ
17h 34m
2 stops
American Airlines Logo
7:00 am - 10:52 pm
SDQ
-
DSM
16h 52m
2 stops
$654American Airlines
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
4:48 pm - 9:27 am
DSM
-
SDQ
15h 39m
2 stops
American Airlines Logo
1:57 pm - 10:04 pm
SDQ
-
DSM
9h 07m
1 stop
$704American Airlines
Wed, Jul 15 - Wed, Jul 22
Delta Logo
5:41 am - 1:17 pm
DSM
-
SDQ
6h 36m
1 stop
Delta Logo
7:35 pm - 10:45 am
SDQ
-
DSM
16h 10m
2 stops
$740Delta
Tue, Jul 14 - Tue, Jul 21
American Airlines Logo
1:04 pm - 12:57 pm
DSM
-
SDQ
22h 53m
1 stop
American Airlines Logo
1:57 pm - 10:04 pm
SDQ
-
DSM
9h 07m
1 stop
$750American Airlines
Wed, Jul 15 - Wed, Jul 22
American Airlines Logo
6:11 am - 6:40 pm
DSM
-
SDQ
11h 29m
2 stops
American Airlines Logo
2:20 pm - 12:09 am
SDQ
-
DSM
10h 49m
2 stops
$780American Airlines
Wed, Jul 15 - Wed, Jul 22
Delta Logo
5:41 am - 1:17 pm
DSM
-
SDQ
6h 36m
1 stop
Delta Logo
2:42 pm - 10:29 pm
SDQ
-
DSM
8h 47m
1 stop
$790Delta
Tue, Oct 27 - Sat, Oct 31
United Airlines Logo
8:15 pm - 2:06 pm
DSM
-
SDQ
16h 51m
2 stops
United Airlines Logo
3:18 pm - 11:20 am
SDQ
-
DSM
21h 02m
2 stops
$795United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santo Domingo flights

Get data-powered insights and trends into flights from Des Moines to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 3 days.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Santo Domingo were found on American Airlines ($654) and Delta ($740).

Good to know

Cheapest flight$654
Flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santo Domingo

  • What is the cheapest flight from Des Moines to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Des Moines to Santo Domingo was $654 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santo Domingo?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Des Moines to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santo Domingo are Delta and American Airlines. With an average price for the route of $574 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $643 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8402 reviews
7.8Comfort
7.8Entertainment
8.1Boarding
8.5Crew
7.2Food
Airline reviews

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

6.0 GoodDouglas, Jun 2026
SLC - CLT
Read more Delta reviews

Average seat comfort, a drink and chips were provided, early boarding because we checked a carryon at the gate was nice. Ticket pricing shenanigans, including fees to pick a seat, check a bag, and get food onboard - evidence the industry is reinvigorating last century’s strategies- destroys the experience before one ever arrives at the airport. It’s difficult to recognize any value or sustain loyalty in the end-to-end process making air travel more drudgery than pleasure.

Gate agent was unhelpful for handicapped boarding. Flight attendant seemed untrained.

No service flight that took 5 hrs and a stop at an unscheduled airport. Crew and pilots did their jobs

Clean planes and not take my comfort class seat away.

The crew were efficient. The pilots seemed professional. It was a bit chilly in our seats. The sheet provided weren’t very helpful.

Weather caused a long delay, but the efficiency and updates from the pilot were helpful. We were able to make our connection fortunately.

Planes were clean, no water or snacks on either flight.

Free & relatively fast Wi-Fi. Would've liked a wider drink selection.

I continue to be satisfied with Delta’s excellent service out of LGA. The digit id works well and gets me through security in no time. Whenever possible, I choose Delta.

Was revoked with Jet Blue due to delay from Kenya Air

The flight from Dallas to Tokyo was not on Japan Airlines. It was on American Airlines. Very disappointed that we did not fly on Japan Airlines. Will not be using you liars again. I’ll just book direct from the airline next time. Wish you could make this right and has us fly on Japan Air when heading back home to the US.

The Mario was so helpful and provided amazing customer service however l have being waiting for a callback for almost a week now and have not heard anything further after l informed them l wanted to change my date of traveling because of my hospital appointment even send them proof and l was unable to use manag your booking on their website is a bit frustrating and l would appreciate an update on My request as soon as possible. And have called them times without numbers no response

They made nearly everyone check their bag because the overhead bins are way too small. Extremely inconvenient

Delayed delayed. Poor professionalism. Our seats changed and we pay for them

Was put into a seat right behind the toilet that had no entertainment possible but did have plenty of leg room over noisy part of plane.

B-class on an old plane with antiquated amenities and poor service. Landed in Rome w/o bag that didn’t make the connection (plenty of time in London). Bag will come to hotel NOT the day it lands but the following night!! Still waiting for bag…BA had nothing to offer in support and couldn’t even tell me their comp, told to submit receipts and then I’ll learn what is or isn’t covered.

Movies on my phone are great. It would be nice to have a gluten free snack option.

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

Everything you need to know for your flight from Des Moines to Santo Domingo

Information on your arrival and departure airports