DSM - SDQ

$377 Find Cheap Flights from Des Moines to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$615
Multiple Airlines
Sun 6/28Sun 7/5
DSM - SDQ • 1 stop
Cheapest one-way
$377
American Airlines
Fri 7/31
DSM - SDQ • 2 stops
Top airlines
American Airlines
Cheapest • from $664 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Atlanta (ATL)
Cheapest • Avg $712 (round-trip)
Atlanta (ATL)
Shortest trip • 6h 47m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Sun, Jun 28 - Sun, Jul 5
Multiple Airlines Logo
5:02 pm - 11:06 am
DSM
-
SDQ
17h 04m
1 stop
Multiple Airlines Logo
12:18 pm - 10:47 pm
SDQ
-
DSM
11h 29m
1 stop
$615Multiple Airlines
Tue, Jun 30 - Tue, Jul 7
American Airlines Logo
6:55 am - 6:35 pm
DSM
-
SDQ
10h 40m
2 stops
American Airlines Logo
2:20 pm - 12:09 am
SDQ
-
DSM
10h 49m
2 stops
$664American Airlines
Tue, Jun 30 - Tue, Jul 7
American Airlines Logo
6:02 am - 6:35 pm
DSM
-
SDQ
11h 33m
2 stops
American Airlines Logo
7:00 am - 8:51 pm
SDQ
-
DSM
14h 51m
2 stops
$672American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
5:25 am - 10:55 pm
DSM
-
SDQ
16h 30m
2 stops
American Airlines Logo
10:29 am - 12:12 am
SDQ
-
DSM
14h 43m
2 stops
$705American Airlines
Tue, Jun 30 - Tue, Jul 7
American Airlines Logo
7:00 am - 10:55 pm
DSM
-
SDQ
14h 55m
2 stops
American Airlines Logo
1:57 pm - 10:04 pm
SDQ
-
DSM
9h 07m
1 stop
$722American Airlines
Sun, Jun 28 - Sun, Jul 5
Multiple Airlines Logo
5:02 pm - 4:29 pm
DSM
-
SDQ
22h 27m
2 stops
Multiple Airlines Logo
12:18 pm - 10:47 pm
SDQ
-
DSM
11h 29m
1 stop
$725Multiple Airlines
Fri, Jun 12 - Fri, Jun 19
Multiple Airlines Logo
7:35 am - 5:29 am
DSM
-
SDQ
20h 54m
1 stop
Multiple Airlines Logo
6:10 am - 1:50 pm
SDQ
-
DSM
8h 40m
1 stop
$731Multiple Airlines
Sat, Sep 26 - Wed, Sep 30
United Airlines Logo
6:00 am - 10:46 pm
DSM
-
SDQ
15h 46m
2 stops
United Airlines Logo
3:20 pm - 10:31 am
SDQ
-
DSM
20h 11m
2 stops
$735United Airlines
Tue, Jun 30 - Tue, Jul 7
American Airlines Logo
5:30 am - 6:35 pm
DSM
-
SDQ
12h 05m
2 stops
American Airlines Logo
1:57 pm - 10:04 pm
SDQ
-
DSM
9h 07m
1 stop
$747American Airlines
Sun, Jun 28 - Sun, Jul 5
American Airlines Logo
6:02 am - 10:55 pm
DSM
-
SDQ
15h 53m
2 stops
American Airlines Logo
7:40 pm - 12:56 pm
SDQ
-
DSM
18h 16m
2 stops
$753American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santo Domingo flights

Get data-powered insights and trends into flights from Des Moines to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Santo Domingo were found on American Airlines ($664) and United Airlines ($735).

Find deals

Good to know

Cheapest flight$377
Flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santo Domingo

  • What is the cheapest flight from Des Moines to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Des Moines to Santo Domingo was $377 for a one-way ticket and $615 for a round-trip.

  • Do I need a passport to fly between Des Moines and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santo Domingo?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Des Moines to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santo Domingo are Delta and American Airlines. With an average price for the route of $613 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $643 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8453 reviews
7.8Entertainment
8.5Crew
7.2Food
8.1Boarding
7.8Comfort
Airline reviews

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

10.0 ExcellentBenjamin, May 2026
CLT - MSP
Read more Delta reviews

Enjoyed it very much. Especially liked the free WiFi that Delta offers.

Smooth flight. Left on time, and got in 15 minutes early. Onboard video was great

For some reason, TSA Atlanta didn’t have my bag on the flight on time and they don’t have to provide Delta a reason for that.

WiFi didn’t work on two of four planes. Flight attendants were not overly friendly or welcoming. Planes were extremely slow to board and deplane.

Delta does a great job with entertainment and free wifi. I can still be in touch with my colleagues while in the air.

Aside from a completely packed plane, I really have no complaints.

Bus to plane was delayed for no apparent reason and our luggage was still on the belt when they shut it off. Took about 20 minutes to turn it back on to get our luggage.

It was a pleasant surprise to have complimentary Wi-Fi on the flight

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

Fine. Nothing to write home about. The plane left on time, and arrived on time.

I was downgraded from first class to coach due to an airplane change. They pulled me out of line and I was the very last person to board the plane stuck in the middle seat with no overhead place to put my carry-.on. Very poor customer service.

Seat comfort was poor (no lumbar or lower back support).

The airplane seats were spacious and comfortable, and the flight attendants were friendly and attentive. The food was delicious like never before. The blankets and toiletries were thoughtfully provided. The captain's navigation was steady and reliable. In short, having flown with Starlux, I won't consider any other airline next time.

STOP MAKING THE SEATING SO CRAMPED. WE NEED A PASSENGER BILL OF RIGHTS!

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

We had several flights and they were all on-time and flawless

My Frequent Flyer nber wasn't put on as I was told it was..... This resulted in a last group boarding and no priority tags on My bags.

Premium Economy Good crew, good service, excellent food. Seat back screen just not bright enough.

Terrible steward... Plane was quite empty... I asked to move "back" in the plane and the steward said no... Unnecessary power trip of mediocre people.

Everything you need to know for your flight from Des Moines to Santo Domingo

Information on your arrival and departure airports

Des Moines (DSM)
Santo Domingo (SDQ)