DSM - SDQ

$522 Find Cheap Flights from Des Moines to Santo Domingo

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Wed, Dec 3 - Wed, Dec 10
American Airlines Logo
6:00 am - 5:23 pmDSM-SDQ
9h 23m2 stops
American Airlines Logo
3:06 pm - 11:29 pmSDQ-DSM
10h 23m1 stop
$522American Airlines
Find Deal
Sat, Nov 29 - Sun, Dec 7
American Airlines Logo
5:26 pm - 2:04 pmDSM-SDQ
18h 38m2 stops
American Airlines Logo
6:00 am - 10:04 pmSDQ-DSM
18h 04m2 stops
$562American Airlines
Find Deal
Mon, Jan 5 - Tue, Jan 6
Multiple Airlines Logo
6:35 am - 2:54 amDSM-SDQ
18h 19m2 stops
Multiple Airlines Logo
3:59 am - 3:40 pmSDQ-DSM
37h 41m3 stops
$590Multiple Airlines
Find Deal
Sat, Nov 29 - Sun, Dec 7
Delta Logo
5:35 am - 2:42 pmDSM-SDQ
7h 07m1 stop
Delta Logo
8:43 pm - 10:38 amSDQ-DSM
15h 55m2 stops
$592Delta
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Mon, Jan 5 - Tue, Jan 6
Multiple Airlines Logo
6:35 am - 2:54 amDSM-SDQ
18h 19m3 stops
Multiple Airlines Logo
3:59 am - 3:40 pmSDQ-DSM
37h 41m3 stops
$624Multiple Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Delta Logo
5:34 am - 2:42 pmDSM-SDQ
7h 08m1 stop
Delta Logo
3:57 pm - 10:34 pmSDQ-DSM
8h 37m1 stop
$642Delta
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Wed, Dec 10 - Thu, Jan 8
American Airlines Logo
6:00 am - 5:23 pmDSM-SDQ
9h 23m2 stops
American Airlines Logo
6:00 am - 3:15 pmSDQ-DSM
11h 15m2 stops
$643American Airlines
Find Deal
Sat, Nov 29 - Sun, Dec 7
American Airlines Logo
5:42 am - 11:45 pmDSM-SDQ
16h 03m2 stops
American Airlines Logo
6:23 pm - 10:28 amSDQ-DSM
18h 05m2 stops
$646American Airlines
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Tue, Mar 24 - Thu, Mar 26
Delta Logo
5:45 am - 11:42 pmDSM-SDQ
16h 57m2 stops
Delta Logo
7:05 am - 8:53 pmSDQ-DSM
14h 48m2 stops
$670Delta
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Thu, Dec 18 - Thu, Dec 25
United Airlines Logo
8:00 am - 11:46 pmDSM-SDQ
13h 46m2 stops
United Airlines Logo
6:00 am - 9:40 pmSDQ-DSM
17h 40m2 stops
$1,464United Airlines
Find Deal

Everything you should know

Top airlines
American Airlines
Cheapest • from $522 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$522
American Airlines
Wed 12/3Wed 12/10
DSM - SDQ • 2 stops
Cheapest one-way
Multiple Airlines
Tue 11/4
DSM - SDQ • multi-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Booking Insights

KAYAK's insights & trends for Des Moines to Santo Domingo flights

Get data-powered insights and trends into flights from Des Moines to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Santo Domingo were found on American Airlines ($522) and Delta ($592).

Which airlines fly non-stop between Des Moines and Santo Domingo?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to Santo Domingo.

There are 2 airlines that fly nonstop from Des Moines to Santo Domingo. They are American Airlines and Delta. The cheapest airline for this route is Delta, with the best round-trip deal found costing $524. On average, the best prices for this route can be found at Delta.

Find deals

Good to know

Low seasonAugust
Cheapest flight$522
Best time to beat the crowds with an average 26% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santo Domingo

  • What is the cheapest flight from Des Moines to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Des Moines to Santo Domingo was $522 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santo Domingo?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Des Moines to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santo Domingo are Delta and American Airlines. With an average price for the route of $574 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $694 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Des Moines to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8003 reviews
7.9Entertainment
7.9Comfort
7.3Food
8.2Boarding
8.5Crew
Airline reviews

I truly love flying with Delta. They have always treated me with the upmost respect

10.0 ExcellentMAYRA, Nov 2025JFK - MIA
Read more Delta reviews

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Old plane and old configuration/seats but still comfortable for a morning flight

We loved the steward on the plane. He made the night enjoyable

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

Flight delay was communicated before leaving for airport which caused it to be a non-event. Great flight and crew!

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Everything you need to know for your flight from Des Moines to Santo Domingo

Information on your arrival and departure airports

Des Moines (DSM)
Santo Domingo (SDQ)

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