DSM - SDQ

$680 Find Cheap Flights from Des Moines to Santo Domingo

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$680
Delta
Tue 8/25Fri 9/11
DSM - SDQ • 1 stop
Top airlines
Cheapest • from $680 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $712 (round-trip)
Shortest trip • 6h 47m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Tue, Aug 25 - Fri, Sep 11
Delta Logo
5:40 am - 1:28 pm
DSM
-
SDQ
6h 48m
1 stop
Delta Logo
2:53 pm - 10:29 pm
SDQ
-
DSM
8h 36m
1 stop
$680Delta
Fri, Aug 14 - Fri, Aug 21
American Airlines Logo
5:40 am - 6:44 pm
DSM
-
SDQ
12h 04m
2 stops
American Airlines Logo
2:00 pm - 10:06 pm
SDQ
-
DSM
9h 06m
1 stop
$683American Airlines
Fri, Aug 14 - Fri, Aug 21
American Airlines Logo
5:40 am - 6:44 pm
DSM
-
SDQ
12h 04m
2 stops
American Airlines Logo
2:00 pm - 10:06 pm
SDQ
-
DSM
9h 06m
1 stop
$684American Airlines
Tue, Aug 25 - Fri, Sep 11
Delta Logo
6:00 am - 6:06 pm
DSM
-
SDQ
11h 06m
2 stops
Delta Logo
7:35 pm - 10:46 am
SDQ
-
DSM
16h 11m
2 stops
$685Delta
Fri, Aug 14 - Fri, Aug 21
American Airlines Logo
1:09 pm - 1:00 pm
DSM
-
SDQ
22h 51m
1 stop
American Airlines Logo
2:00 pm - 12:34 pm
SDQ
-
DSM
23h 34m
1 stop
$689American Airlines
Fri, Aug 14 - Fri, Aug 21
American Airlines Logo
1:09 pm - 1:00 pm
DSM
-
SDQ
22h 51m
1 stop
American Airlines Logo
2:00 pm - 12:34 pm
SDQ
-
DSM
23h 34m
1 stop
$690American Airlines
Fri, Aug 7 - Mon, Aug 10
American Airlines Logo
5:40 am - 6:44 pm
DSM
-
SDQ
12h 04m
2 stops
American Airlines Logo
2:00 pm - 10:06 pm
SDQ
-
DSM
9h 06m
1 stop
$695American Airlines
Fri, Aug 7 - Mon, Aug 10
Delta Logo
5:40 am - 1:28 pm
DSM
-
SDQ
6h 48m
1 stop
Delta Logo
2:53 pm - 10:37 pm
SDQ
-
DSM
8h 44m
1 stop
$700Delta
Sat, Jul 11 - Thu, Jul 16
Multiple Airlines Logo
4:59 pm - 7:18 pm
DSM
-
SDQ
25h 19m
2 stops
Multiple Airlines Logo
12:18 pm - 9:27 pm
SDQ
-
DSM
10h 09m
1 stop
$741Multiple Airlines
Sat, Oct 31 - Tue, Nov 3
United Airlines Logo
6:52 pm - 1:41 pm
DSM
-
SDQ
17h 49m
2 stops
United Airlines Logo
6:00 am - 9:35 pm
SDQ
-
DSM
17h 35m
2 stops
$755United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santo Domingo flights

Get data-powered insights and trends into flights from Des Moines to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Des Moines to Santo Domingo were found on Delta ($680) and American Airlines ($683).

Good to know

Cheapest flight$680
Flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santo Domingo

  • What is the cheapest flight from Des Moines to Santo Domingo?

    In the last 5 days, the lowest price for a flight from Des Moines to Santo Domingo was $680 for a round-trip ticket.

  • Do I need a passport to fly between Des Moines and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santo Domingo?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Des Moines to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santo Domingo are Delta and American Airlines. With an average price for the route of $574 and an overall rating of 7.8, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $643 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8452 reviews
7.2Food
8.5Crew
7.8Comfort
7.8Entertainment
8.1Boarding
Airline reviews

Everything about this flight was good except for the very end when I reached my destination. Everyone from the tune to the wheelchair escorts were great with the case were great but I miss you with people at the check in this at the very end. I need help from the chicken desk because I forgot my pillow on the plane The female worker at the chicken desk said that they found my pillow and she was going to retrieve it for me. She left a 30 minutes without any update and her so she saw me walking back and forth waiting for her and they didn't even bother calling her or radioing her for any updates. They were busy because they were behind schedule and they were overwhelmed but thanks because at least glanced me and try to give me an update just a quick radio check or phone call. I don't care about the pillow but if you tell me to wait, I waited for at least half an hour before I said something and I just left because they wouldn't bother talking to me so I could, so everything's going in the review. I took pictures of the two men that were left working at the check-in counter. The totally ignored me despite the signals I've been giving them. I don't see any offers in the kayak review to add pictures or screenshots so I'm going to post another review I don't know their name but I'm pretty sure Delta will find other names when they see the review. Google with pictures. There was another guy at the chicken counter bring an orange workers vest who finally left after telling me that the girl that was retrieving my pillow is working the gates now. That would have been if they just told me that's what happened. But I had no update. Make me wait for nothing. Thank you Delta airlines!

6.0 GoodNghia, Jun 2026
DTW - OMA
Read more Delta reviews

Everything about this flight was good except for the very end when I reached my destination. Everyone from the tune to the wheelchair escorts were great with the case were great but I miss you with people at the check in this at the very end. I need help from the chicken desk because I forgot my pillow on the plane The female worker at the chicken desk said that they found my pillow and she was going to retrieve it for me. She left a 30 minutes without any update and her so she saw me walking back and forth waiting for her and they didn't even bother calling her or radioing her for any updates. They were busy because they were behind schedule and they were overwhelmed but thanks because at least glanced me and try to give me an update just a quick radio check or phone call. I don't care about the pillow but if you tell me to wait, I waited for at least half an hour before I said something and I just left because they wouldn't bother talking to me so I could, so everything's going in the review. I took pictures of the two men that were left working at the check-in counter. The totally ignored me despite the signals I've been giving them. I don't see any offers in the kayak review to add pictures or screenshots so I'm going to post another review I don't know their name but I'm pretty sure Delta will find other names when they see the review. Google with pictures. There was another guy at the chicken counter bring an orange workers vest who finally left after telling me that the girl that was retrieving my pillow is working the gates now. That would have been if they just told me that's what happened. But I had no update. Make me wait for nothing. Thank you Delta airlines!

We had a great experience with Delta. They helped us from the start at the kiosk all the way to our final destination, including help reassigning and upgrading our seats free of charge at the gates, escorts with the wheelchair for my brother and even getting our luggage at baggage claim for us. I also had special help because I forgot my pillow on the plane. The wheelchair escort contacted for associates at the check-in desk all the way back to the plane and retrieved my pillow for me.

Crew was real good, flight was smooth and came in early.

The CRJ-900 was clean but the overhead air vents were broken in our First Class row, making the cabin very hot until about 30 mins into the flight. The flight attendants were both extremely apologetic and accommodating though so that is why I rated the flight as very good. They checked on us many times and truly showed they cared. The snacks for an hour and a half flight could be better. Would be nice if there was a small plated meal over convenient store snacks. WiFi also was not working. And it would be nice if Delta had adjustable headrests on these planes.

New high end luggage ruined/zippers broken, items missing. All happened on return flight from msp to mso. Do better! Not store bought luggage but high end personalized ogio custom embroidered luggage. Total slap in the face ontop of an extra luggage fee that took me 3 hrs on chat to resolve.

It was as good as it could be. Flying is not a pleasant experience these days.

The plane was old and thus the seats were not good. No cushion left whatsoever, and it all was a bit worn out.

I am writing to express my dissatisfaction with the poor service and unprofessional staff we encountered when traveling with an infant. Our flight was delayed, and the gate staff failed to manage the boarding process appropriately. Due to incorrect, unavailable, or missing 'pink tag' stroller and car seat check-in procedures at the gate, we were forced to board last. Furthermore, the gate staff was rude and dismissive, causing significant distress to our infant. To make matters worse, one of our checked items—an infant sleeper/lounger—was returned to us broken. Given the unsafe handling of essential equipment and unprofessional treatment, I expect a prompt resolution regarding compensation for the damaged items.

None of the airplane features were available during the flight.

Old plane and old configuration/seats but still comfortable for a morning flight

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The boarding process needs to be fixed. The zone don't work, especially when there is hardly anyone in zones 3, 4,and 5, leaving the majority of the passengers backed up in the aisle, especially because passengers seated near the front are blocking passengers who are seated in the rear of the plane. It would also help if the size of carry on bags was more strictly enforced.

In flight connectivity (via T-Mobile) was often not working.

We got upgraded for this flight. But the particular bright spot was the flight attendant in our cabin. She was attentive but not intrusive. She interacted in a personal way with each passenger and gave a great service. Thank you!

Terrible. Internet/kiosk glitch prevented baggage checkin. Line at ticket co in Ter was under serviced and did not move. Agents did not call for flight but rather allowed time to pass. Then told each person as they reached the front if line that it was too late to check bags so they’d have to rebook flights. At least 15 people missed the flight as a result of this incompetence.

It was exactly what I expected, actually arriving sooner than scheduled.

Terrible, they canceled my flight due to an issue they had, couldn't fly me into the same place within 24 hrs so had to fly in 2.5 hrs away from my destination and spend even more money. The customer service was terrible (except at the airport in Charleston). Had to call to get my checked baggage fees reimbursed 2 wks later in which one customer service agent was very rude, wouldn't listen and then hung up on me. The second lady I spoke with was actually able to help me with that part thankfully. Would not recommend flying AA.

Delayed, missed connecting flight, ground crew double charged for international charges, were super rude and told me to just”deal with it” when I complained. Horrible airline, very frustrating.

Horrible costumer service i was treated very bad the crew were rude 😟 didn’t get my wheelchair that I requested I was the last one the get in because no seat was assigned and after my 2 stroke I cannot be on my feet for too long but they didn’t care didn’t take my medicine on time because all the complications and delays when my bag was sent already I hope yall can train your crew better.

Crowed but safe flight and arrived at my destination on time

Everything you need to know for your flight from Des Moines to Santo Domingo

Information on your arrival and departure airports