DSM - SDQ

$237 Find Cheap Flights from Des Moines to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Santo Domingo departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Santo Domingo, as well as popular online travel agencies
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41 299 237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$448
Multiple Airlines
Sun 5/3Sun 5/10
DSM - SDQ • 1 stop
Cheapest one-way
$237
Multiple Airlines
Thu 4/2
DSM - SDQ • 1 stop
Top airlines
Cheapest • from $613 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $725 (round-trip)
Shortest trip • 6h 46m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Sun, May 3 - Sun, May 10
Multiple Airlines Logo
7:00 am - 2:35 am
DSM
-
SDQ
18h 35m
1 stop
Multiple Airlines Logo
2:35 pm - 10:57 pm
SDQ
-
DSM
33h 22m
2 stops
$448Multiple Airlines
Sun, Apr 19 - Wed, Apr 22
Multiple Airlines Logo
7:00 am - 2:40 am
DSM
-
SDQ
18h 40m
1 stop
Multiple Airlines Logo
2:35 pm - 4:00 pm
SDQ
-
DSM
26h 25m
1 stop
$463Multiple Airlines
Sun, Apr 26 - Thu, Apr 30
Multiple Airlines Logo
8:30 am - 1:29 pm
DSM
-
SDQ
27h 59m
1 stop
Multiple Airlines Logo
2:35 pm - 10:06 pm
SDQ
-
DSM
8h 31m
1 stop
$464Multiple Airlines
Sun, Apr 26 - Thu, Apr 30
Multiple Airlines Logo
7:00 am - 1:29 pm
DSM
-
SDQ
29h 29m
2 stops
Multiple Airlines Logo
2:35 pm - 10:06 pm
SDQ
-
DSM
8h 31m
1 stop
$511Multiple Airlines
Sun, Apr 19 - Wed, Apr 22
Multiple Airlines Logo
8:30 am - 1:29 pm
DSM
-
SDQ
27h 59m
1 stop
Multiple Airlines Logo
7:10 pm - 4:00 pm
SDQ
-
DSM
21h 50m
2 stops
$515Multiple Airlines
Thu, Apr 9 - Sat, Apr 11
Multiple Airlines Logo
7:00 am - 2:40 am
DSM
-
SDQ
18h 40m
1 stop
Multiple Airlines Logo
2:52 am - 10:06 pm
SDQ
-
DSM
20h 14m
1 stop
$556Multiple Airlines
Thu, Apr 9 - Sat, Apr 11
Multiple Airlines Logo
2:36 pm - 10:07 am
DSM
-
SDQ
18h 31m
2 stops
Multiple Airlines Logo
2:52 am - 10:06 pm
SDQ
-
DSM
20h 14m
1 stop
$604Multiple Airlines
Sun, Apr 19 - Tue, Apr 28
United Airlines Logo
7:16 pm - 11:55 am
DSM
-
SDQ
15h 39m
2 stops
United Airlines Logo
1:10 pm - 11:17 pm
SDQ
-
DSM
11h 07m
2 stops
$613United Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
5:50 am - 10:55 pm
DSM
-
SDQ
16h 05m
1 stop
American Airlines Logo
1:45 pm - 9:58 pm
SDQ
-
DSM
9h 13m
1 stop
$629American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
6:02 am - 10:55 pm
DSM
-
SDQ
15h 53m
2 stops
American Airlines Logo
7:35 pm - 12:52 pm
SDQ
-
DSM
18h 17m
2 stops
$633American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Santo Domingo flights

Get data-powered insights and trends into flights from Des Moines to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to Santo Domingo were found on United Airlines ($613) and American Airlines ($629).

Good to know

Cheapest flight$237
Most popular time to fly and prices are also 23% lower on average.
Flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Santo Domingo

  • What is the cheapest flight from Des Moines to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Des Moines to Santo Domingo was $237 for a one-way ticket and $430 for a round-trip.

  • Do I need a passport to fly between Des Moines and Santo Domingo?

    Yes, you’ll need a passport to travel to Santo Domingo from Des Moines.

  • Which airports will I be using when flying from Des Moines to Santo Domingo?

    When flying out of Des Moines you will be using Des Moines. You will be landing at Santo Domingo, also known as Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Des Moines to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Santo Domingo?

    oneworld, and SkyTeam are the airline alliances operating flights between Des Moines and Santo Domingo, with oneworld being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Santo Domingo are Delta and American Airlines. With an average price for the route of $613 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $684 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Des Moines to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8303 reviews
8.1Boarding
7.8Entertainment
7.9Comfort
8.5Crew
7.2Food
Airline reviews

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

2.0 MediocreAnonymous, Mar 2026
HNL - ATL
Read more Delta reviews

the crew cancel the morning service due to the weather. Then the flight got deverted to Nashville . we were on the ground for over two hours the only gave us water once... no food or any snacks.... the crew should have handled better and offered something to passengers.

My recent experience was excellent on Delta! I flew with Delta Comfort and I was really comfortable in my seat. I enjoyed the in-flight service. The flight attendants were so friendly and hospitable. I love the snack on the flight as well. This was my first time flying on Delta and I will definitely consider flying with them again.

My flight was cencaled due with the bad weather on Sunday the crew was poorly mistaken my luggage supposed depart with my flight instead I didn’t have my luggage for almost 3 days the website is poorly respond to my complain until I have someone to do it my connection smooth their not even respon or email me even the have my luggage

Delta needs to step its game up get a more reliable internet service. Internet service was non-existent for this flight.

Mechanical Delay of over an hour with multiple gate changes. Entertainment system down for rejuvenation.

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

Rough flight No beverage service due to turbulence Bottom Seat cushion was non existent

Great experience. Good dinner and service. FA's were very nice and attentive.

It was great. Smooth flight, comfortable, left on time and landed on time.

Perhaps this is an airport issue, but being in a takeoff queue for over an hour in the taxiing lane is unacceptable. We will definitely be seeking alternative avenues for air travel in the future.

We hoarded. Then we deplaned. Then we waited for 10 hours in the MSP airport due to a wheel misfunction. We understand safety but communication between crew and airport staff was horrible. When we did finally board, we were rushed on and because we were waiting for a “fresh” pilot and crew, we sat in a roasting plane with no A/C for an hour. My question is why was this flight not cancelled right away when they knew this would be a huge issue OR, why did AA not get a substitute plane, considering this was already a full flight? To me, this appears to be a complete breakdown in leadership and utter systems failure. The compensation for completely disrupting travel plans for hundreds, which we paid dearly for, was measly. While we appreciated the lodging for the night, $12 in meal vouchers isn’t going to sustain anyone for over 12 hours. “We apologize; our hands are tied” is no longer an acceptable explanation. We are so completely turned off by this experience and will definitely seek alternative avenues when we need to fly.

Mostly good. The WiFi wasn’t working so that was not great.

I rated the experience "mediocre" because of the 2 hour delay in take off. This is the 4th flight from DFW on AA where there was a delay and in one of the instances (after 13 delays), the flight was cancelled. I understand weather but for the March 18th flight, there was no weather issue in Dallas or Detroit. I called Concierge Key and they were wonderful, booking me on a later flight in case my flight was cancelled. I have flown with American for many years and never has there been this consistent pattern of delays. Very disappointing.

They put me on an earlier and I got home sooner

Not good. One of my luggage is missing. And until now they can’t find it

Horrible experience upon landing. Probably more due to DCA utter incompetence than AA.

Everything you need to know for your flight from Des Moines to Santo Domingo

Information on your arrival and departure airports