DSM - SDQ

$414 Find Cheap Flights from Des Moines to Santo Domingo - Compare and Save

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Everything you should know

Cheapest round-trip
$677
Typical prices: $633-$799
Multiple Airlines
Thu 11/29Tue 12/11
DSM - SDQ • 2 stops
Cheapest one-way
$414
Typical prices: $363-$481
Multiple Airlines
Mon 11/5
DSM - SDQ • 3 stops
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 5% price drop
May
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Fort Lauderdale (FLL)
Cheapest • Avg $707 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 7h 46m (one-way)
Insights
Insights
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We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Sun, Nov 29 - Fri, Dec 11
Multiple Airlines Logo
7:05 pm - 12:04 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
38h 59m2 stops Orlando Sanford Intl Philadelphia
Multiple Airlines Logo
6:10 am - 2:00 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
9h 50m1 stop Newark
$677Multiple Airlines
Mon, Nov 30 - Fri, Dec 11
Multiple Airlines Logo
1:26 pm - 12:04 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
20h 38m2 stops Orlando Sanford Intl Philadelphia
Multiple Airlines Logo
6:10 am - 2:00 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
9h 50m1 stop Newark
$689Multiple Airlines
Tue, Dec 1 - Tue, Dec 8
United Airlines Logo
9:30 am - 11:46 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
12h 16m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
6:00 am - 7:19 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
15h 19m2 stops Newark Chicago O'Hare Intl
$699United Airlines
Mon, Nov 30 - Sun, Dec 13
Multiple Airlines Logo
1:26 pm - 12:04 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
20h 38m2 stops Orlando Sanford Intl Philadelphia
Multiple Airlines Logo
2:25 pm - 2:10 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
25h 45m1 stop Orlando
$736Multiple Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
7:36 am - 10:04 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
12h 28m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
10:58 am - 11:33 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
14h 35m2 stops Miami Washington, D.C. Reagan-National
$750American Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
10:57 am - 9:56 amDSM  Des Moines-SDQ Santo Domingo Las Americas
20h 59m2 stops Charlotte Douglas Miami
American Airlines Logo
10:58 am - 11:33 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
14h 35m2 stops Miami Washington, D.C. Reagan-National
$755American Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
3:31 pm - 9:56 amDSM  Des Moines-SDQ Santo Domingo Las Americas
16h 25m2 stops Dallas/Fort Worth Miami
American Airlines Logo
12:41 pm - 11:33 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
12h 52m2 stops Miami Washington, D.C. Reagan-National
$755American Airlines
Wed, Dec 2 - Wed, Dec 9
Delta Logo
6:53 pm - 1:34 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
16h 41m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl
Delta Logo
3:57 pm - 10:38 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
8h 41m1 stop Atlanta Hartsfield-Jackson
$786Delta
Wed, Dec 2 - Fri, Dec 11
Delta Logo
5:29 pm - 1:34 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
18h 05m2 stops Detroit Metropolitan Wayne County New York LaGuardia
Delta Logo
8:53 pm - 10:49 amSDQ  Santo Domingo Las Americas-DSM Des Moines
15h 56m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
$786Delta
Tue, Dec 1 - Tue, Dec 15
Delta Logo
6:13 am - 2:25 amDSM  Des Moines-SDQ Santo Domingo Las Americas
18h 12m2 stops Detroit Metropolitan Wayne County New York LaGuardia
Delta Logo
7:00 am - 7:15 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
14h 15m1 stop New York John F Kennedy Intl
$786Delta
Booking Insights

Price, demand and travel trends for Des Moines to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from Des Moines to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Des Moines to Santo Domingo. It’s 5% cheaper than the average day, while Sunday is the most expensive, with prices 56% higher.

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Key details for Des Moines to Santo Domingo flights

Low season

October

Cheapest flight

$414
Beat the crowds with an average 82% drop in travelers.
The most popular month to fly with an average 49% increase in travelers.
One-way flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Santo Domingo?

    Only Economy Class is available on flights from Des Moines to Santo Domingo.

  • How long is a flight from Des Moines to Santo Domingo?

    A nonstop flight from Des Moines to Santo Domingo takes 00m, covering 2,131 miles.

  • Do I need a passport to fly from Des Moines to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Des Moines to Santo Domingo flight?

    Round-trip flights from Des Moines to Santo Domingo range from $633 to $799, with an average of $665 over the past 12 months. Anything below $633 counts as a good deal.

  • Have flight prices from Des Moines to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $677 to $3,775. That means the highest observed fare was about 6x higher than the lowest one.

  • How are flight prices from Des Moines to Santo Domingo looking right now?

    One-way fares from Des Moines to Santo Domingo are currently higher than usual. Average one-way flight prices are about $758, which is 83% above the typical average for this route.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around $7 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from Des Moines to Santo Domingo?

    Flights from Des Moines to Santo Domingo usually depart from Des Moines (DSM) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Des Moines to Santo Domingo pass through?

    One-stop flights from Des Moines to Santo Domingo most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 61% of one-stop connections
    • Miami (MIA) - 28% of one-stop connections
    • Fort Lauderdale (FLL) - 11% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Santo Domingo?

    Yes. Flexible dates can save you up to 40% on flights from Des Moines to Santo Domingo. Monday is the cheapest departure day at $633 round-trip on average, while Sunday is the most expensive at $1,044, a difference of $411.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to Santo Domingo?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 46m, compared with 8h 37m via Fort Lauderdale (FLL) and 8h 59m via Miami (MIA).

  • What is the time difference between Des Moines and Santo Domingo?

    Santo Domingo is 1 hour ahead of Des Moines (Atlantic Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

Your guide to booking Des Moines to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure and avoid flying on Sunday. On this route, Monday flights average $633, about $411 less than Sunday fares (39% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Santo Domingo trip for January. Fares historically average $631 round-trip in that month - typically $416 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from Des Moines to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo