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DSM - SDQ

$340 Find Cheap Flights from Des Moines to Santo Domingo - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$685
Typical prices: $633-$799
United Airlines
Wed 11/7Wed 11/14
DSM - SDQ • 2 stops
Cheapest one-way
$340
Typical prices: $363-$481
Multiple Airlines
Thu 11/1
DSM - SDQ • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Des Moines and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 5% price drop
May
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Fort Lauderdale (FLL)
Cheapest • Avg $707 (round-trip)
Atlanta Hartsfield-Jackson (ATL)
Shortest trip • 7h 46m (one-way)
Insights
Insights
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We hope you love your trip to Santo Domingo!
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Booking Insights
Flight Deals

Cheap Flights from Des Moines to Santo Domingo (DSM-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Santo Domingo

Sat, Nov 7 - Sat, Nov 14
United Airlines Logo
11:23 am - 11:46 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
10h 23m2 stops Chicago O'Hare Intl Newark
United Airlines Logo
6:00 am - 7:16 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
15h 16m2 stops Newark Chicago O'Hare Intl
$685United Airlines
Fri, Nov 6 - Fri, Nov 13
Multiple Airlines Logo
8:30 pm - 9:19 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
46h 49m2 stops Denver Intl Miami
Multiple Airlines Logo
6:24 am - 2:21 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
9h 57m1 stop Boston Logan Intl
$716Multiple Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
10:57 am - 9:56 amDSM  Des Moines-SDQ Santo Domingo Las Americas
20h 59m2 stops Charlotte Douglas Miami
American Airlines Logo
10:58 am - 11:33 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
14h 35m2 stops Miami Washington, D.C. Reagan-National
$735American Airlines
Fri, Jan 15 - Fri, Jan 29
American Airlines Logo
6:14 pm - 3:16 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
19h 02m2 stops Dallas/Fort Worth Miami
American Airlines Logo
10:58 am - 11:40 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
14h 42m2 stops Miami Charlotte Douglas
$735American Airlines
Fri, Jan 8 - Fri, Jan 22
American Airlines Logo
3:31 pm - 9:56 amDSM  Des Moines-SDQ Santo Domingo Las Americas
16h 25m2 stops Dallas/Fort Worth Miami
American Airlines Logo
12:41 pm - 11:33 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
12h 52m2 stops Miami Washington, D.C. Reagan-National
$755American Airlines
Fri, Jan 15 - Fri, Jan 29
American Airlines Logo
6:14 pm - 3:16 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
19h 02m2 stops Dallas/Fort Worth Miami
American Airlines Logo
10:58 am - 10:16 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
13h 18m2 stops Miami Dallas/Fort Worth
$755American Airlines
Fri, Jan 15 - Fri, Jan 29
American Airlines Logo
6:14 pm - 3:16 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
19h 02m2 stops Dallas/Fort Worth Miami
American Airlines Logo
10:58 am - 11:59 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
15h 01m1 stop Miami
$755American Airlines
Tue, Nov 24 - Tue, Dec 1
American Airlines Logo
5:01 am - 2:43 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
7h 42m1 stop Miami
American Airlines Logo
3:46 pm - 11:44 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
9h 58m1 stop Miami
$781American Airlines
Wed, Feb 24 - Sun, Feb 28
American Airlines Logo
5:00 am - 6:18 pmDSM  Des Moines-SDQ Santo Domingo Las Americas
11h 18m1 stop Miami
American Airlines Logo
6:00 am - 11:56 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
19h 56m2 stops Miami Charlotte Douglas
$785American Airlines
Wed, Feb 24 - Sun, Feb 28
American Airlines Logo
2:03 pm - 9:58 amDSM  Des Moines-SDQ Santo Domingo Las Americas
17h 55m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
6:00 am - 11:56 pmSDQ  Santo Domingo Las Americas-DSM Des Moines
19h 56m2 stops Miami Charlotte Douglas
$785American Airlines
Booking Insights

Price, demand and travel trends for Des Moines to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Des Moines to Santo Domingo?

Round-trip flights from Des Moines to Santo Domingo typically range from $633 to $799. The lowest price found in the past 5 days was $685, on United Airlines.

What's the cheapest day of the week to fly from Des Moines to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Des Moines to Santo Domingo. It’s 5% cheaper than the average day, while Sunday is the most expensive, with prices 56% higher.

Find deals

Key details for Des Moines to Santo Domingo flights

Low season

October

Cheapest flight

$340
One-way flight from Des Moines to Santo Domingo

When to book flights from Des Moines to Santo Domingo

Are your dates flexible? Find out the best times to travel from Des Moines to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Des Moines to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Des Moines to Santo Domingo?

    Only Economy Class is available on flights from Des Moines to Santo Domingo.

  • How long is a flight from Des Moines to Santo Domingo?

    A nonstop flight from Des Moines to Santo Domingo takes 00m, covering 2,131 miles.

  • Do I need a passport to fly from Des Moines to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Des Moines to Santo Domingo flight?

    Round-trip flights from Des Moines to Santo Domingo range from $633 to $799, with an average of $665 over the past 12 months. Anything below $633 counts as a good deal.

  • How are flight prices from Des Moines to Santo Domingo looking right now?

    One-way fares from Des Moines to Santo Domingo are currently in line with typical prices for this route. Average one-way fares are about $429.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around $7 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from Des Moines to Santo Domingo?

    Flights from Des Moines to Santo Domingo usually depart from Des Moines (DSM) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Des Moines to Santo Domingo pass through?

    One-stop flights from Des Moines to Santo Domingo most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 61% of one-stop connections
    • Miami (MIA) - 28% of one-stop connections
    • Fort Lauderdale (FLL) - 11% of one-stop connections

  • Can I save money by using flexible dates for flights from Des Moines to Santo Domingo?

    Yes. Flexible dates can save you up to 40% on flights from Des Moines to Santo Domingo. Monday is the cheapest departure day at $633 round-trip on average, while Sunday is the most expensive at $1,044, a difference of $411.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Des Moines to Santo Domingo?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 46m, compared with 8h 37m via Fort Lauderdale (FLL) and 8h 59m via Miami (MIA).

  • What is the time difference between Des Moines and Santo Domingo?

    Santo Domingo is 1 hour ahead of Des Moines (Atlantic Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

Your guide to booking Des Moines to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure and avoid flying on Sunday. On this route, Monday flights average $633, about $411 less than Sunday fares (39% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Des Moines to Santo Domingo trip for January. Fares historically average $631 round-trip in that month - typically $416 less than the most expensive month, which is August (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from Des Moines to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo