$227 Find Cheap Flights from Detroit to Panama - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Booking Insights
Flight Deals
Booking Insights

Price, demand and travel trends for Detroit Metropolitan Wayne County Airport to Panama flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Are flights from Detroit Metropolitan Wayne County Airport to Panama cheaper or more expensive than last year?

Fares from Detroit Metropolitan Wayne County Airport to Panama are running about 14% higher than they were around this time last year, averaging $900 round-trip.

What are the cheapest fares from Detroit Metropolitan Wayne County Airport to Panama right now?

The cheapest fares from Detroit Metropolitan Wayne County Airport to Panama on KAYAK in the last week were to Panama City Tocumen Intl (PTY) from $529 round-trip, and to David Enrique Malek (DAV) from $1,009 round-trip.

What’s the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama?

January is the cheapest time of year to fly, with average fares of $781. Prices are highest in April, when average flight costs increase to around $1,198.

When is the best time to book flights from Detroit Metropolitan Wayne County Airport to Panama?

Book your flights 18 weeks before your trip. KAYAK data collected over the past 12 months shows that booking in this window can save you around 47% compared to booking last-minute (within 2 weeks of departure).

Which airport in Panama is the cheapest to fly to from Detroit Metropolitan Wayne County Airport?

Based on KAYAK data from the past 12 months, the cheapest airports to fly into Panama are:

• Panama City Tocumen Intl (PTY) from $909
• David Enrique Malek (DAV) from $1,201

What’s the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Panama?

Tuesday tends to be the cheapest day to fly from Detroit Metropolitan Wayne County Airport to Panama, while Wednesday is the most expensive. Fares run about 35% higher that day, based on the past 12 months of KAYAK data.

What's the cheapest time of day to fly from Detroit Metropolitan Wayne County Airport to Panama?

Data from the past 12 months shows it's cheapest to fly to Panama during the night with average prices of $836. The afternoon is the most expensive time to fly, with average prices of $1,343.

Key details for Detroit Metropolitan Wayne County Airport to Panama flights

Low season

August

Cheapest flight

$227
Beat the crowds with an average 83% drop in travelers.
The most popular month to fly with an average 176% increase in travelers.
One-way flight from Detroit Metropolitan Wayne County Airport to Panama City

Your Detroit Metropolitan Wayne County Airport to Panama flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • Is now a good time to book a flight from Detroit Metropolitan Wayne County Airport to Panama?

    Yes. Fares from Detroit Metropolitan Wayne County Airport to Panama are low right now. As a rule of thumb, a round-trip under $767 (cheaper than most fares this year) is a good deal, so if you spot one at or below that, it's a good time to book.

  • How much should I budget for a flight from Detroit Metropolitan Wayne County Airport to Panama?

    Over the past 12 months, round-trip fares from Detroit Metropolitan Wayne County Airport to Panama have ranged from $767 to $1,188.

  • What are the main airports serving Panama?

    Flights to Panama use two main airports, Panama City Tocumen Intl (PTY) and David Enrique Malek (DAV).

  • What airlines fly nonstop from Detroit Metropolitan Wayne County Airport to Panama?

    Based on the flight schedule for the next 3 months, no airline regularly operates nonstop flights from Detroit Metropolitan Wayne County Airport to Panama. One-stop options include:

    • Delta
    • United Airlines
    • American Airlines

  • Which cabin classes are available on flights from Detroit Metropolitan Wayne County Airport to Panama?

    On flights from Detroit Metropolitan Wayne County Airport to Panama you can book Economy Class or First Class.

  • What are some popular landmarks in Panama?

    KAYAK travelers' favorite landmarks in Panama include:

    • ATLAPA Conventions Center
    • Panama Old Cathedral
    • Veneto Casino
    • Ancon Hill

Your guide to booking Detroit Metropolitan Wayne County Airport to Panama flights

Get tips on when to book, when to fly and what to know before your trip.
  • If you can plan ahead, the sweet spot for booking your flight is 18 weeks before your trip. KAYAK data shows fares in this window are around 47% lower than last-minute bookings (made within 2 weeks of departure). Not ready to commit? Set a Price Alert and we'll let you know when prices change.
  • If your travel dates are flexible, book your trip for January when flights are typically cheapest and avoid April when prices are at their highest.
  • Flying on Tuesday is usually the cheapest. Flights on Wednesday cost about 35% more on average, so being flexible with your travel dates could help you save.
  • If you're looking to save, Panama City Tocumen Intl (PTY) is the cheapest airport to fly into from Detroit Metropolitan Wayne County Airport. If you have onward travel, don't forget to factor in the cost of your journey by train, bus or domestic flight.
  • Start your trip in Panama City, which is the most popular destination in Panama. From there, it's easy to continue on to other popular destinations such as Bocas del Toro, Río Hato and Boquete.

Reviews of the top 4 airlines serving from Detroit to Panama

 
Need help choosing which airline to fly with from Detroit to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8636 reviews
7.8Entertainment
8.1Boarding
8.5Crew
7.8Comfort
7.2Food
Airline reviews

Great quik boarding, friendly gate agent and crew. Let early

10.0 ExcellentCharles, Sep 2026
Read more Delta reviews

Great quik boarding, friendly gate agent and crew. Let early

We sat at the gate for over 30 minutes, with no indication as to why

All was fine. Small plane so no food or entertainment.

Very aggressive at the boarding area of only allowing one person passed a line/ sign

Delayed 7 hours Crew and employees were nice Extra long flight but at least we got in

I love how the flight crews are now saying what the weather will be like, when we can expect to be able to get up and use the restrooms etc. I have to say also that our flight crews this trip were incredible - fast and courteous - and somehow managed to do the service even on these short flights with a few bumps. The only reason for an ok rating on entertainment was because these short flights are on planes without seatback displays but that's ok because I just download shows on my iPhone beforehand.

Our flight from Detroit to LaGuardia on Thursday 8/20 was delayed from 555 to 910 due to storms and a ground stop at LGA. It’s never fun to be stuck at the airport but I thought the desk crew and captain handled it well and kept us informed. I especially liked how they referred to us as their “LaGuardia family.” I am a loyal delta customer and this is one of the reasons why.

The plane is old. There was water dripping fown from the air cooling system. The toilets were mot that clean

The meal tray was not usable it was completely uneven

Staff is friendly and helpful but flight was delayed by one hour from Detroit, making for tight window in Toronto to clear Canada Customs and pass through security screening in order to get to connecting flight on time.

It is not a good experience with Copa Airlines: flight delay, luggage delay, etc.

We where skipped for this flight will not head to Panama until tonight..

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

This flight is a quick way to get to Chicago, but a bit expensive.

Didn't make the flight because the first leg of my flight was canceled and the next leg was already booked.

We got delayed three hours and nobody thought to have the bathroom fixed while we were sitting waiting to board? took a full hour to have maintenance come and check it off. Had to shut the bathroom down twice so that the pilots could go to the bathroom. Everyone missed their connections.

Not good - outbound flight was delayed and missed my connection even though I got to the gate after running through the airport - the agent would not let me on because the door was closed (flight had not left). There was no notification from United - overall experience was very disappointing. Additionally, I was downgraded from first class to coach on the alternative flight

Same as last comment. Food sucks. Quality. Not surprising most people have no clue about nourishment Clearly

Crew was excellent. This was a relatively long flight though and had very little leg room, and no entertainment.

I liked that the flight was nonstop from ORD to CIU for $200 round trip.

Some sort of compensation for missing work because of a cancelled flight that was United’s fault

I was told we'd have a hot breakfast option in first class, so I chose not get a hot breakfast. It was a very strange meal, but the fresh fruit was very good quality. Service was excellent from ORD to ELP. No service from MBS to ORD, not even water. However, when flying American from FNT to ORD, which is a shorter flight, they at least pass out snacks and offer water.

Staff friendly and app worked really well. Modest delays were frustrating

I sat in seat 22D near the back right of the plane. My phone battery was getting low, so I plugged my charger into the power outlets below the seats in front of me. They did not work. When I asked the flight attendant whether this was the case for the whole plane he said, "No. It's only this one. It hasn't worked for months". This should be noted to whomever services this plane so that maintenance can fix this for future passengers. I was on Flight AA5614 from Grand Rapids to Philadelphia on Wednesday, September 23, 2026.

The passenger in front of of me reclined their seat back all the way the entire flight. Their headrest was in my face the entire flight! I barely had room for the little plastic cup of water to fit on my tray table; can you make the seats and space between the rows any smaller??? You can’t even get up to use the restroom! Worst flight I’ve had in a very long time!

I was on a small regional flight from Detroit to Philadelphia. When we landed the outside cruise needed to turn something off with the engine, which took quite a long time. Then, when they allowed us to get off the plane it was outside. They took their time, unloading all the luggage and waited till they unloaded all the luggage before they brought it over to us. It was 9 o’clock at night freezing cold out, and there was no proactive hustle to try to get people their luggage. It was really one of the worst experiences I think I’ve ever had with American until a manager came over. I don’t think they were going to even consider pulling the luggage over to the people that had been waiting outside for at least 10 minutes in the freezing cold.

It was a good trip. Flight Attendants were friendly and responsive.

They should have allowed for extra time to de-ice the plane before boarding passengers. This delayed us about 10-15 mins after we boarded. Overall experience was fine. Crew was friendly and on top of everything. We didn’t have any issues during the flight.

The trip was very smooth and they provided great customer service

It was on time, which is always a good thing. There wasn’t any food hence my okay rating.

It was a crazy day with a lot of delays and gate changes. Not a huge fan of the Charlotte hub at all.

We have been delayed and postponed 2days and nights…and still do not have our flight until tomorrow..

American Airlines is awful!! Will never fly with them again. Connection flight left early leaving 22 people in Charlotte with no way to get to Key West for 24 hours. Would not provide hotel or any other accommodations. Bags were delayed two days.

More options for your flight from Detroit to Panama

Complete your trip to Panama with a hotel stay or car rental