$160 Find Cheap Flights from Detroit to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to Panama departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Detroit to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to Panama

Thu, Apr 9 - Thu, Apr 16
Multiple Airlines Logo
10:24 am - 7:20 pm
DTW
-
PTY
9h 56m
1 stop
Multiple Airlines Logo
8:10 am - 6:44 pm
PTY
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DTW
9h 34m
1 stop
$458Multiple Airlines
Sat, Apr 11 - Thu, Apr 16
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5:20 am - 3:54 pm
DTW
-
PTY
11h 34m
1 stop
Multiple Airlines Logo
8:10 am - 6:44 pm
PTY
-
DTW
9h 34m
1 stop
$463Multiple Airlines
Mon, Apr 6 - Mon, Apr 13
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4:50 pm - 2:15 pm
DTW
-
PTY
22h 25m
2 stops
Multiple Airlines Logo
3:10 pm - 10:37 pm
PTY
-
DTW
30h 27m
3 stops
$527Multiple Airlines
Mon, Mar 30 - Tue, Apr 7
Multiple Airlines Logo
4:50 pm - 8:30 am
DTW
-
PTY
16h 40m
1 stop
Multiple Airlines Logo
9:33 pm - 11:12 am
PTY
-
DTW
12h 39m
2 stops
$530Multiple Airlines
Fri, Apr 10 - Mon, Apr 13
Multiple Airlines Logo
4:50 pm - 1:55 am
DTW
-
PTY
34h 05m
3 stops
Multiple Airlines Logo
3:05 am - 10:37 pm
PTY
-
DTW
18h 32m
3 stops
$533Multiple Airlines
Sun, Mar 22 - Sat, Mar 28
Multiple Airlines Logo
5:45 am - 1:00 am
DTW
-
PTY
20h 15m
2 stops
Multiple Airlines Logo
9:45 am - 12:20 pm
PTY
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DTW
25h 35m
2 stops
$535Multiple Airlines
Fri, Apr 10 - Mon, Apr 13
Multiple Airlines Logo
4:50 pm - 9:15 am
DTW
-
PTY
17h 25m
2 stops
Multiple Airlines Logo
3:05 am - 10:37 pm
PTY
-
DTW
18h 32m
3 stops
$537Multiple Airlines
Fri, Apr 10 - Thu, Apr 16
Multiple Airlines Logo
5:20 am - 7:20 pm
DTW
-
PTY
15h 00m
1 stop
Multiple Airlines Logo
8:10 am - 6:44 pm
PTY
-
DTW
9h 34m
1 stop
$551Multiple Airlines
Mon, Apr 6 - Mon, Apr 13
Multiple Airlines Logo
6:05 am - 2:15 pm
DTW
-
PTY
33h 10m
3 stops
Multiple Airlines Logo
10:10 am - 10:37 pm
PTY
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DTW
35h 27m
3 stops
$552Multiple Airlines
Mon, Mar 30 - Tue, Apr 7
Multiple Airlines Logo
4:50 pm - 2:15 pm
DTW
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PTY
22h 25m
2 stops
Multiple Airlines Logo
3:50 pm - 11:59 pm
PTY
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DTW
31h 09m
2 stops
$553Multiple Airlines
Booking Insights

KAYAK's insights & trends for Detroit to Panama flights

Get data-powered insights and trends into flights from Detroit to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to Panama is June, when tickets cost $723 (return) on average. On the other hand, the most expensive months are December and February, when the average cost of round-trip tickets is $879 and $873 respectively.

Good to know

Low seasonFebruary
Cheapest flight$160
Best time to beat the crowds but there is an average 10% increase in price.
Most popular time to fly with an average 10% increase in price.
Flight from Detroit to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Detroit to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Detroit to Panama

 
Need help choosing which airline to fly with from Detroit to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8284 reviews
7.2Food
8.5Crew
7.8Entertainment
7.9Comfort
8.1Boarding
Airline reviews

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

2.0 MediocreIsabella, Mar 2026
SLC - AUS
Read more Delta reviews

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

Stop changing gates. Stop cancelling flights Stop moving my seat.

Extremely disappointed with Delta. They canceled flight last minute and then I rebooked the other flights and with which were delayed as well

Could not get my connecting flight boarding pass until four hrs before departure! Ver annoying especially since the staff could not explain why!

The flight was flying with 30% capacity. The flight my seat from preferred seating to back of the seat. Even though i can understand that this was to balance the flight weight. The flight attendance decided to do the serving near my seat and in the middle , their noices woke me up from sleep , when i realized that the service has ended and when they were going back asked for a coffee, for which they answered they have completed teh service in my location. That really upset me as they woke me up and also rejected the coffee i asked. I ended up landing with a headache, thanks to the crew that screwed up my travel

Delayed. Hot. Passenger next to me was so large I couldn’t move.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

The boarding process doesn't make sense since some people that will sit behind your rows are boarded before you and then they take up the luggage space above your head. I then have to wait for people to get off the plane before I can go back to get my luggage.

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

The travel company that you have on your site did me so wrong. I don’t know how it happened, but they put my son‘s name on my plane ticket flying to Vietnam. Along with his birthday. They would not have let me fly from Fort Myers to Ho Chi Minh City. I don’t think that I can ever use your service again. I typed my information into the browser along with my passport number and four days before I’m leaving I have to quickly search another ticket to fly out here.

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

The flight was delayed so we were dead tired, and after that the turbulence was horrible. I was very scared.

It’s always a great time flying with united airlines.

Good flight. Efficient boarding and competent flight crew. No problems until we arrived at our destination gate. We were early so there was an aircraft at the gate that had to move before we could pull in. Then, due to the type of aircraft we flew, the cabin door could not be opened until some luggage from the cargo bay was offloaded to preserve center of gravity characteristics. So, that further delayed deplaning. Despite being 20 minutes early on landing, we ended up being 5 to 10 minutes late after all the delays.

Everything went well except the turbulence what no one have a control of but pilot and crew handled very good!

There was no WiFi available, there were mechanical problems with the plane and we landed at C 124, then the gate was switched to A 26, then all the way back to C126! For a 75 yo woman traveling alone, this was a difficult journey, indeed!

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

Appreciate having multiple food options for allergies. Nice to have an extra seat between us for comfort.

Check in was rough because the check in crew did not know how to manage my international visa documents. Required a long process and 4 people to finally be able to proceed to security. They told us incorrect information several times before acknowledging we did indeed have everything we needed from the start.

Where do I start!! I was delayed with my flight from Dallas to Tampa. On the way back from Tampa to Dallas the flight was delayed over 4 hours+. I was put on another flight that was also delayed but not as long. Traveling on American Airlines is becoming exhausing.

There was no inflight service. Once we landed we were delayed to find a gate for an hour and a half which was 1/2 the total time in the air.

The gate got changed several times and the flight was delayed over an hour. Awful experience

Poor communication ahead of time about flight delays and old planes/other equipment.

The flight was delayed multiple times. I was autobooted and placed in the center seat in the last row of the plane.

My flight was delayed. We left at midnight. I got to Greensboro (GSO) at 1am. All of AA's flights in/out of Charlotte always seem to be delayed or canceled. It took me all day on Sunday to get to my destination of Cincinnati from Greensboro. I had to be rerouted through Chicago because my original flight was canceled as the door to plane was closing in GSO. The saddest part is I could have driven and arrived sooner. . . I recognize there is a lot going on that impacts travel. This week it was weather. Yesterday in Cincinnati it was President Trump. But as a frequent flyer, the flight from South Bend to Charlotte always runs late. The subsequent flight to Greensboro is always midnight to 2am. . . I do want to give props the Charlotte boarding crew. They had four flights going out of the same area at the same time. They turned it quickly and mitigated the grumbling from the crowd.

Never going to fly your airline again if it can be avoided.

Dloght delayed by 2.5 hrs . Common theme in my last four american floghts

Everything you need to know for your flight from Detroit to Panama

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