Find cheap flights from Detroit to Panama from $307

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
Round-trip
1 adult
Economy
0 bags
Sat 6/24
Sat 7/1

Here is why travelers choose KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Bundle and saveSave money when you bundle your flight + hotel.

Search hundreds of travel sites at once for deals on flights to Panama

Latest Panama Flight Deals

Best round-trip prices found by our users on KAYAK in the last 72 hours

MOST POPULARPanama City
2+ stops from $505

Good to know

Low season

May

High season

December

Cheapest flight

$307

Average price round-trip

$490
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Detroit to Panama City
(price for this month)

Top tips for finding cheap flights to Panama

  • Book at least 2 weeks before departure in order to get a below-average price.
  • High season is considered to be January, February and December. The cheapest month to fly from Detroit is April.
  • Morning departure is around 1% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

FAQs - booking Panama flights

Top 3 airlines serving from Detroit to Panama

Scores according to KAYAK customer reviews
7.9
DeltaOverall score based on 29352 reviews
78comfort
75food
78entertainment
81boarding
81overall
85crew
Airline reviews
Pros: "No entertainment on the plane and plane was very small..."
Cons: "Explain flight situations better.."
Read more about Delta
Pros: "No entertainment on the plane and plane was very small..."
Cons: "Explain flight situations better.."
Pros: "Crew was very friendly and took good care of the passengers"
Pros: "Flight was smooth and short"
Cons: "The entertainment system kept resetting over and over throughout the flight. And drinks were served late in a not so comfortable temperature cabin. But everything else was ok"
Pros: "The flight was safe and efficient."
Cons: "The seats on the 787 Dreamliner proved to be uncomfortable AGAIN this trip. 2 years ago we flew the 787 overnight and the seats were the same. Hard cushions, tight seat pitch, and little room to move about."
Pros: "Good flight as always with Delta. Sat in economy comfort, so of course the seats was comfortable. Flight Attendants were great."
Cons: "B.S. all the Delta Boarding groups. Geez, have you lost all common sense! C'mon... I understand the ill/med conditions passengers. How about 1 kid, then 2 kids then 3 kids, w/ cataracts, bladder probelems, Platinum, Gold, Silver, Paper, Plus 1, Plus 2, Main Cabin 1, 2 and 3."
Cons: "It could have left on time or they could have told us they weren’t leaving and let us get some sleep."
Cons: "The baggage drop attendant was very unhelpful when I asked if she could help me sort out an issue (when I checked in online for the second leg of my trip, i paid for my bag then but they wanted me to pay again for my first flight) and just dismissed me and said she couldn't help, making me pay again for my bag. First time I've ever had an unpleasant experience with Delta."
Pros: "It was too cold on the flight. I asked for a blanket and luckily the stewardess had one. However, before giving it to me, she told me it was the only one on the flight!"
Cons: "Separated from my wife even with pre-assigned seats. And One of the stewardess would not take my banana peel and has asked me to dump it into lavatory trash myself. She did not want to handle banana peel without a glove."
Cons: "Flight was totally full... At least everyone had a mask on American does not space seats like Delta does I will be taking Delta whenever possible"
Pros: "Leg room"
Cons: "The onboard crew was rude and one guy actually grabbed me which to me is unprofessional. All because I had a poster tube that wasn't in my bag they wanted it in my bag. Then I asked for a seat change due to my size hard for ne to be in the middle and the lady was snooty about it."
Pros: "Very uncomfortable seating even though paid for preferred. Not enough space for carry on."
Cons: "Crew service"
Cons: "I bought WiFi for my iPhone on the flight and could barely use it because it kept kicking me off and was super slow."
Pros: "Flight attendants were amazing. Definitely some of the best I've ever encountered."
Cons: "Crew at the desk were rude. They also enacted policies that I'd never seen before about gate checking, and implied I was crazy when I noted how unusual it was. I literally came off a previous AA flight with the previous policy and they said I was confusing them with AE."
Cons: "O prematurely had to check my carry on when there was room to bring it on board with me"
Pros: "The snacks."
Cons: "This was the worst flight I've ever been on. Delayed 7 hours. Made it to deicing pad only to be told we needed to turn back to the gate due to technical issues. Kept being told 15 more minutes until departure."
Pros: "Th flight was a few minutes late boarding but we landed on time. It was a nice smooth flight!"
Pros: "The staff were polite and the pilot kept us on time. The flight wasn’t over booked and I was able to have an extra seat between myself and the other passenger in my row."
Cons: "That due to the Kayak purchase I had to wait until the last group to board."
Pros: "It was on time. I liked the head rests on the seats."
Pros: "The flight crew was friendly and smiling."
Cons: "The seat in economy was incredibly uncomfortable. Seat had a slight forward incline which made a finding a relaxing position impossible."
Cons: "I was in business class and was terrible The airplane too old , so expensive for that? Can’t believe it..."
Pros: "All I got was a $20 food voucher for a 9 hour delay and missed meeting."
Cons: "All I got was a $20 food voucher for a 9 hour delay and missed meeting."
Pros: "The crew was super attentive and cordial."
Cons: "United Airlines has really deteriorated. Paid entertainment for an international flight is really nickle-and-diming it, especially since it was direct tv which is only available over the continental US!"
Cons: "We were delayed in Detroit due to deicing the plane. We landed in Houston late. They let us and a few other couples off the plane first so we could make our connection. We sprinted off the plane and arrived to the gate two minutes after they closed the door; plane was still there and they would not let us on. United knew we were coming and they closed the door anyway. The next flight out to Liberia, Costa Rica wasn’t for two more days. They ended up rebooking us on a flight to Panama which had a connection to San Jose, Costa Rica. Much farther of a drive from that airport. Very disappointed in how United handled this situation, we were told if it was a bigger group they would have held the plane for us. I will never fly United again but I know it has nothing to do with Kayak. Kayak has always been great and is my go to for booking plane tickets."
Cons: "I left New Jersey during snow storm. Flights had been cancelled on the previous days but our flight was not. It did not leave on time, had to switch planes before we actually took off. My luggage was lost. I did not make my connecting flight. Had sty over in Panama. Got to my destination a day late without my carry on ( checked at the gate...lost). Still have not located my other 2 bags. Very stressful expirence. Will not fly united again. Staff at my lay over was poorly trained at handling the situation and my luggage issue is taking a very long time to correct."
Pros: "The flight was fine. Nothing that should have been positive stands out as missing."
Cons: "The first class flight attendant (male) was the worst. No interest in being on the plane, didn't bother to speak clearlybon the announcements. United should pull this person off of flight duty and deal with this person. The second is a terrible parent who let their kid cry the whole flight and afterwards in the jet way. This wasn't an infant had to be 4-5 years old and there was no parenting at all. The kid was old enough to be talked to. If you're kids can't handle flying, you don't get to fly."
Pros: "The crew did a great job helping us on board and talking us through changing our connections."
Cons: "The flight into Newark was delayed four hours because the airport was shut down for political officials. This probably should've been expected."
Cons: "The flight was delayed and was given another longer flight and had to pay for the luggage twice. Totally disappointed."
Pros: "I loved the pilot taking time to greet my boys and give them wings! My boys loved sitting in the co-pilot's seat and hearing "the plane talk." Once we got to our seats, the flight attendants were very helpful and kind and we, actually, landed early! Yaaayyy! My boys won't forget their flight to Houston because of the cool female and male pilots they met while traveling. Thank you!"
Cons: "I did NOT like how the seats are grouped in twos. I flew with two small children who could only sit together and I had to sit by myself and watch them; which was very hard. If I could change anything about my flight, I would change the age of children who need to purchase seats to four and up as most children under 4 want to sit with their mothers, so why should I pay for a seat they will not be using?"

Book cheap flights from Detroit to Panama

Recent round-trip flight deals

8/24Thu
2 stopsMultiple Airlines
19h 22mDTW-PTY
8/28Mon
2 stopsMultiple Airlines
29h 51mPTY-DTW
$505
8/24Thu
2 stopsMultiple Airlines
19h 22mDTW-PTY
8/27Sun
2 stopsMultiple Airlines
29h 51mPTY-DTW
$517
8/15Tue
2 stopsAmerican Airlines
17h 46mDTW-PTY
8/24Thu
2 stopsAmerican Airlines
20h 33mPTY-DTW
$546
8/15Tue
1 stopAmerican Airlines
7h 17mDTW-PTY
8/24Thu
2 stopsAmerican Airlines
20h 33mPTY-DTW
$548
7/27Thu
2 stopsMultiple Airlines
19h 39mDTW-PTY
8/1Tue
2 stopsMultiple Airlines
28h 46mPTY-DTW
$557
7/3Mon
1 stopMultiple Airlines
12h 32mDTW-PTY
7/7Fri
2 stopsMultiple Airlines
23h 01mPTY-DTW
$560
10/8Sun
1 stopAmerican Airlines
8h 41mDTW-PTY
10/12Thu
1 stopAmerican Airlines
9h 35mPTY-DTW
$563
7/27Thu
1 stopMultiple Airlines
11h 56mDTW-PTY
8/1Tue
2 stopsMultiple Airlines
28h 46mPTY-DTW
$564
7/3Mon
1 stopMultiple Airlines
12h 32mDTW-PTY
7/7Fri
1 stopMultiple Airlines
18h 37mPTY-DTW
$565
10/8Sun
2 stopsAmerican Airlines
9h 06mDTW-PTY
10/12Thu
2 stopsAmerican Airlines
18h 28mPTY-DTW
$566
8/24Thu
1 stopAmerican Airlines
7h 17mDTW-PTY
8/26Sat
2 stopsAmerican Airlines
20h 33mPTY-DTW
$568
8/24Thu
2 stopsAmerican Airlines
17h 46mDTW-PTY
8/26Sat
2 stopsAmerican Airlines
23h 21mPTY-DTW
$586
8/24Thu
1 stopMultiple Airlines
11h 39mDTW-PTY
8/28Mon
1 stopMultiple Airlines
10h 47mPTY-DTW
$595
7/27Thu
2 stopsMultiple Airlines
19h 39mDTW-PTY
8/1Tue
2 stopsMultiple Airlines
28h 46mPTY-DTW
$597
8/4Fri
1 stopMultiple Airlines
12h 32mDTW-PTY
8/9Wed
1 stopMultiple Airlines
10h 47mPTY-DTW
$602
8/15Tue
1 stopDelta
8h 45mDTW-PTY
8/24Thu
1 stopDelta
7h 47mPTY-DTW
$615
8/15Tue
2 stopsAmerican Airlines
9h 03mDTW-PTY
8/24Thu
2 stopsAmerican Airlines
21h 02mPTY-DTW
$617
8/15Tue
1 stopAmerican Airlines
7h 17mDTW-PTY
8/24Thu
2 stopsAmerican Airlines
19h 09mPTY-DTW
$618
8/15Tue
nonstopUndisclosed Carrier
5h 36mDTW-PTY
8/24Thu
nonstopUndisclosed Carrier
3h 36mPTY-DTW
$627
9/1Fri
1 stopUnited Airlines
8h 55mDTW-PTY
9/6Wed
1 stopUnited Airlines
23h 15mPTY-DTW
$701

Search by stops

Search by airline

Search by price

Recent one-way flight deals

9/18Mon
2 stopsAmerican Airlines
9h 06mDTW-PTY
$307
9/18Mon
nonstopUndisclosed Carrier
5h 36mDTW-PTY
$383

Search by stops

Search by airline

Search by price

Flights to Panama

Return flight deals:

Panama - Detroit

Cabin classes:

Browse origins:

Browse destinations: