$232 Find Cheap Flights from Detroit to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to Panama departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Detroit to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to Panama

Mon, Mar 16 - Mon, Mar 30
Multiple Airlines Logo
4:50 pm - 8:50 am
DTW
-
PTY
17h 00m
2 stops
Multiple Airlines Logo
5:55 pm - 12:20 pm
PTY
-
DTW
17h 25m
2 stops
$484Multiple Airlines
Mon, Mar 16 - Mon, Mar 30
Multiple Airlines Logo
4:50 pm - 8:50 am
DTW
-
PTY
17h 00m
2 stops
Multiple Airlines Logo
5:55 pm - 10:37 pm
PTY
-
DTW
27h 42m
3 stops
$503Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
Multiple Airlines Logo
5:20 am - 4:06 pm
DTW
-
PTY
11h 46m
1 stop
Multiple Airlines Logo
9:33 pm - 12:20 pm
PTY
-
DTW
13h 47m
1 stop
$506Multiple Airlines
Mon, Mar 16 - Mon, Mar 30
Multiple Airlines Logo
5:20 am - 4:06 pm
DTW
-
PTY
11h 46m
1 stop
Multiple Airlines Logo
9:33 pm - 12:20 pm
PTY
-
DTW
13h 47m
1 stop
$510Multiple Airlines
Mon, Mar 16 - Mon, Mar 30
Multiple Airlines Logo
5:20 am - 10:30 am
DTW
-
PTY
30h 10m
3 stops
Multiple Airlines Logo
5:55 pm - 10:37 pm
PTY
-
DTW
27h 42m
3 stops
$515Multiple Airlines
Sat, Mar 14 - Thu, Mar 19
Multiple Airlines Logo
2:26 pm - 8:30 am
DTW
-
PTY
19h 04m
1 stop
Multiple Airlines Logo
5:50 pm - 12:20 pm
PTY
-
DTW
17h 30m
2 stops
$516Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
Multiple Airlines Logo
4:50 pm - 8:50 am
DTW
-
PTY
17h 00m
2 stops
Multiple Airlines Logo
9:45 am - 10:37 pm
PTY
-
DTW
35h 52m
3 stops
$517Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Multiple Airlines Logo
4:50 pm - 2:15 pm
DTW
-
PTY
22h 25m
2 stops
Multiple Airlines Logo
6:34 pm - 12:20 pm
PTY
-
DTW
16h 46m
1 stop
$520Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Multiple Airlines Logo
5:20 am - 1:55 am
DTW
-
PTY
21h 35m
3 stops
Multiple Airlines Logo
6:34 pm - 12:20 pm
PTY
-
DTW
16h 46m
1 stop
$522Multiple Airlines
Wed, Apr 22 - Wed, Apr 29
Multiple Airlines Logo
5:00 am - 1:05 am
DTW
-
PTY
21h 05m
2 stops
Multiple Airlines Logo
3:05 am - 9:38 pm
PTY
-
DTW
17h 33m
2 stops
$525Multiple Airlines
Booking Insights

KAYAK's insights & trends for Detroit to Panama flights

Get data-powered insights and trends into flights from Detroit to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to Panama is June, when tickets cost $723 (return) on average. On the other hand, the most expensive months are February and March, when the average cost of round-trip tickets is $932 and $927 respectively.

Good to know

Low seasonAugust
Cheapest flight$232
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Detroit to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Detroit to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Detroit to Panama

 
Need help choosing which airline to fly with from Detroit to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8205 reviews
7.8Entertainment
7.2Food
8.1Boarding
8.5Crew
7.9Comfort
Airline reviews

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

10.0 ExcellentSoosnata, Feb 2026
LAX - HNL
Read more Delta reviews

Everything I mentioned earlier - the airbus was more comfortable indeed and the experience was further enhanced.

Delta continues to set the benchmark for traveler-friendly service with minimal disruption and clear communication within the mainland US (coast to coast). I am consistently pleased to be a Delta customer, and this experience once again met my expectations. There was a brief delay departing from MIA due to a technical issue that required the aircraft to return to the gate. However, the situation was handled professionally and transparently. Fortunately, my planned layover allowed ample buffer time, so the adjustment caused no stress. Overall, another smooth and reassuring experience.

Good experience and the flight landed early. There was no food I had or entertainment.

Flight was delayed and no reasons provided. After the passengers were boarded, the crew made announcement that the captain has jot arrived and he would take another 15 mins. All passengers patiently sat until the captain came and started. Terrible experience!

Flight was delayed. No information on why it was delayed. After we boarded the flight, , the crew made announcement that the captain hs not arrived and he will take 15 mins more to arrive. Passengers were just sitting patiently for the captain to arrive and start, Terrible experience.

Totally worth the miles to upgrade to Delta Comfort. Plenty of legroom.

This was my first time flying Delta ever and I had a great experience!

Smallest leg room I've ever had on a plane.

They took all carry-on luggage from Groups 6 -9 - I was group 5 and waiting in line to board - they made me check my luggage too. That then went to baggage claim and delayed departure from the airport. There was overhead room in my seating area - Delta over reacted. Also, had a gentleman next to me that took up 1/2 my seat.

Excellent!!! Aeromexico is a great airline. What was not that good is the service provided by Kayak. It is never clear and not easy to manage.

Both the WIFI and entertainment did not work for 2.5h

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

Very old flight - time to retire it for newer airplanes

2+ hours delayed Outlet in row 12 did not work Tv monitors did not work Lights kept off the entire flight for at 5pm-7pm flight

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Boarding delayed 20 minutes for no reason, no wifi, in flight entertainment, or snacks / waters?

Didn't get a seat assignment until the last minute even though i picked a seat.

American has been able to implement an algorithm that makes it possible for nearly every one of my evening flights to be late. Congratulations!

I was on a small regional flight from Detroit to Philadelphia. When we landed the outside cruise needed to turn something off with the engine, which took quite a long time. Then, when they allowed us to get off the plane it was outside. They took their time, unloading all the luggage and waited till they unloaded all the luggage before they brought it over to us. It was 9 o’clock at night freezing cold out, and there was no proactive hustle to try to get people their luggage. It was really one of the worst experiences I think I’ve ever had with American until a manager came over. I don’t think they were going to even consider pulling the luggage over to the people that had been waiting outside for at least 10 minutes in the freezing cold.

The flight was fine, once we got underway. It was more than hour delayed

Beverage service was not good. Also just one service in 5 hr 30 min flight. No ask fir water ir anything beside one time beverage service.

Waited for oxygen tanks for 30 minutes after boarding was complete.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

The flight was on time/early, attentive crew, and everything overall went smoothly. Disappointed that WIFI was not working for the flight.

One day, I do so hope for a gluten free snack! Seems like with the rest of the world FINALLY figuring out what gluten free is, American Airlines would too. Fingers crossed!!

Everything you need to know for your flight from Detroit to Panama

Information on your arrival and departure airports