$249 Find Cheap Flights from Detroit to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to Panama departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Detroit to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to Panama

Mon, May 25 - Sat, May 30
Multiple Airlines Logo
6:00 am - 5:00 pm
DTW
-
PTY
36h 00m
2 stops
Multiple Airlines Logo
4:25 am - 7:52 am
PTY
-
DTW
26h 27m
3 stops
$514Multiple Airlines
Mon, May 25 - Sat, May 30
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6:30 am - 12:35 am
DTW
-
PTY
19h 05m
3 stops
Multiple Airlines Logo
4:25 am - 7:52 am
PTY
-
DTW
26h 27m
3 stops
$527Multiple Airlines
Mon, May 25 - Sat, May 30
Multiple Airlines Logo
6:00 am - 9:15 am
DTW
-
PTY
28h 15m
2 stops
Multiple Airlines Logo
4:25 am - 11:53 pm
PTY
-
DTW
18h 28m
2 stops
$528Multiple Airlines
Tue, May 26 - Tue, Jun 9
Multiple Airlines Logo
6:50 am - 1:55 am
DTW
-
PTY
20h 05m
3 stops
Multiple Airlines Logo
4:25 am - 11:35 am
PTY
-
DTW
30h 10m
3 stops
$590Multiple Airlines
Mon, May 18 - Sat, May 23
Multiple Airlines Logo
6:10 am - 10:30 am
DTW
-
PTY
29h 20m
2 stops
Multiple Airlines Logo
3:50 pm - 11:59 pm
PTY
-
DTW
31h 09m
2 stops
$625Multiple Airlines
Wed, May 27 - Mon, Jun 8
Multiple Airlines Logo
6:05 pm - 8:34 pm
DTW
-
PTY
27h 29m
1 stop
Multiple Airlines Logo
9:33 pm - 4:53 pm
PTY
-
DTW
42h 20m
2 stops
$640Multiple Airlines
Wed, Jun 10 - Wed, Jun 17
Multiple Airlines Logo
5:38 pm - 8:34 pm
DTW
-
PTY
27h 56m
1 stop
Multiple Airlines Logo
5:30 am - 11:59 pm
PTY
-
DTW
17h 29m
2 stops
$646Multiple Airlines
Tue, May 26 - Tue, Jun 9
Multiple Airlines Logo
6:00 am - 8:19 pm
DTW
-
PTY
15h 19m
1 stop
Multiple Airlines Logo
3:41 pm - 4:53 pm
PTY
-
DTW
24h 12m
2 stops
$655Multiple Airlines
Tue, May 26 - Tue, Jun 2
Multiple Airlines Logo
6:00 am - 8:19 pm
DTW
-
PTY
15h 19m
1 stop
Multiple Airlines Logo
9:33 pm - 5:13 pm
PTY
-
DTW
18h 40m
2 stops
$660Multiple Airlines
Tue, Jun 9 - Tue, Jun 16
Multiple Airlines Logo
6:54 pm - 8:34 pm
DTW
-
PTY
26h 40m
1 stop
Multiple Airlines Logo
9:33 pm - 11:59 pm
PTY
-
DTW
25h 26m
1 stop
$666Multiple Airlines
Booking Insights

KAYAK's insights & trends for Detroit to Panama flights

Get data-powered insights and trends into flights from Detroit to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to Panama is March, when tickets cost $514 (return) on average. On the other hand, the most expensive months are February and May, when the average cost of round-trip tickets is $758 and $745 respectively.

Good to know

Low seasonFebruary
Cheapest flight$249
Best time to beat the crowds but there is an average 5% increase in price.
Most popular time to fly with an average 5% increase in price.
Flight from Detroit to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Detroit to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Detroit to Panama

 
Need help choosing which airline to fly with from Detroit to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8465 reviews
7.8Entertainment
7.9Comfort
7.2Food
8.5Crew
8.1Boarding
Airline reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

6.0 GoodSilvestre, Apr 2026
MCO - GRU
Read more Delta reviews

The flight was operated by Latam. The aircraft had a technical issue and the flight was delayed for the next day. They grounded other passengers to get their airplane assigned to my flight. Most of he ground staff don't speak English (Orlando Airport), but were very polite.The crew on the other hand could speak English and Portuguese. On board service was good.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Friendly crew, good food options, food not the best and seats not as comfy but that’s typical.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some crew were unfriendly or in some cases just straight up rude.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

United Airline crews were very friendly and very attentive. 12 hours flight was gone like in a shorter one.

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

Food was surprisingly delicious. Space in the seat is horrible when the seating front is reclined. Movie offerings were terrible. Crew was friendly and helpful.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

Everything you need to know for your flight from Detroit to Panama

Information on your arrival and departure airports