$46 Find Cheap Flights from Detroit to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South Carolina departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Detroit to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$181
Myrtle Beach
Myrtle Beach1 stop$141
Greenville
Greenville1 stop$202
Columbia
Columbia2 stops$208
Charlotte
Charlotte1 stop$148
Charleston
Charleston1 stop$181
Myrtle Beach
Myrtle Beach1 stop$141
Greenville
Greenville1 stop$202
Columbia
Columbia2 stops$208
Charlotte
Charlotte1 stop$148

Book Cheap Detroit to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South Carolina

Mon, Dec 8 - Fri, Dec 12
Spirit Airlines Logo
11:19 am - 8:00 amDTW-MYR
20h 41m1 stop
Spirit Airlines Logo
5:41 pm - 7:44 amMYR-DTW
14h 03m1 stop
$141Spirit Airlines
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Sat, Dec 6 - Sat, Dec 13
Spirit Airlines Logo
9:28 pm - 8:00 amDTW-MYR
10h 32m1 stop
Spirit Airlines Logo
9:05 am - 3:40 pmMYR-DTW
6h 35m1 stop
$142Spirit Airlines
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Wed, Nov 26 - Mon, Dec 1
Multiple Airlines Logo
10:57 am - 9:27 pmDTW-CLT
10h 30m1 stop
Multiple Airlines Logo
7:36 pm - 9:21 pmCLT-DTW
1h 45mnonstop
$148Multiple Airlines
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Wed, Dec 3 - Wed, Dec 10
Delta Logo
10:04 am - 11:59 amDTW-CLT
1h 55mnonstop
Delta Logo
12:44 pm - 2:34 pmCLT-DTW
1h 50mnonstop
$149Delta
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Tue, Dec 9 - Tue, Dec 16
Multiple Airlines Logo
7:08 am - 2:47 pmDTW-CLT
7h 39m1 stop
Multiple Airlines Logo
1:37 pm - 8:29 amCLT-DTW
18h 52m1 stop
$150Multiple Airlines
Find Deal
Thu, Dec 11 - Wed, Dec 17
Delta Logo
2:22 pm - 4:13 pmDTW-CLT
1h 51mnonstop
Delta Logo
6:00 am - 7:55 amCLT-DTW
1h 55mnonstop
$169Delta
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Wed, Feb 18 - Sun, Feb 22
American Airlines Logo
11:14 am - 1:13 pmDTW-CLT
1h 59mnonstop
American Airlines Logo
8:55 pm - 10:50 pmCLT-DTW
1h 55mnonstop
$189American Airlines
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Tue, Dec 9 - Tue, Dec 16
American Airlines Logo
4:46 pm - 11:13 pmDTW-CAE
6h 27m1 stop
American Airlines Logo
6:21 am - 1:40 pmCAE-DTW
7h 19m2 stops
$254American Airlines
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Thu, Dec 11 - Thu, Dec 18
Southwest Logo
7:00 am - 4:05 pmDTW-GSP
9h 05m2 stops
Southwest Logo
8:00 am - 7:50 pmGSP-DTW
11h 50m2 stops
$383Southwest
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Thu, Feb 12 - Mon, Feb 16
Southwest Logo
5:30 am - 10:10 amDTW-GSP
4h 40m1 stop
Southwest Logo
7:40 pm - 11:55 pmGSP-DTW
4h 15m1 stop
$392Southwest
Find Deal
Booking Insights

KAYAK's insights & trends for Detroit to South Carolina flights

Get data-powered insights and trends into flights from Detroit to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Detroit Metropolitan Wayne County Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Detroit Metropolitan Wayne County Airport found in the last 72 hours was to Charleston, at $174 round-trip. The most popular route is from Detroit Metropolitan Wayne County Airport (DTW) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $174.

Can I save money by flying with a layover from Detroit Metropolitan Wayne County Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $402, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South Carolina is August, when tickets cost $224 (return) on average. On the other hand, the most expensive months are February and May, when the average cost of round-trip tickets is $396 and $393 respectively.

What’s the cheapest day of the week to fly from Detroit to South Carolina?

The average price of all round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Detroit to South Carolina, you should consider leaving on a Friday and avoid Sundays if you are looking for the best rates. For your return to Detroit, you’ll find the best rates on Thursdays and the most expensive ones on Sundays.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South Carolina, you should book around 3 weeks before departure, which saves you about 26% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$46
Most popular time to fly with an average 5% increase in price.
Flight from Detroit to Charleston

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Detroit to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $310 on average. Morning departures are around 8% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $414.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Detroit to the following destinations at these prices or less: Charlotte $158 one-way - $289 round-trip

Reviews of the top 4 airlines serving from Detroit to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Detroit to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4238 reviews
7.5Entertainment
8.1Boarding
7.0Food
8.6Crew
8.0Comfort
Airline reviews

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

8.0 ExcellentTODD, Nov 2025DAL - CMH
Read more Southwest reviews

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

Everything a cheap airline should be at normal airline rates.

Plane crashed into a bus or some other vehicle on the ground while pulling out of the gate. No injuries, but wing tip was damaged and returned to gate for “maintenance issues” and we departed 5 hours later because the plane went out of service and new plane was flown in from a nearby airport, Midway.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Full cans of soda would be nice. A choice between two snacks would be appreciated.

Tried watching free movie and it kept freezing so I couldn’t finish.

All was good. I just had a hard time getting connected to the WiFi/internet during the flight

Sacrament staff are always polite and helpful. Airport is easy to maneuver and boarding is straightforward.

Great flight. Outstanding Service. Southwest was able to put us on a direct flight to Denver when the connection could have been affected by a later arrival to Baltimore. The direct flight was less expensive that the flight with the connection in Baltimore.

Delays delays delays. Late taking off, late landing, wait for a gate, etc.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

They changed planes and the new plane couldn’t carry enough fuel to fly across the country so we had to stop in Kansas City to refuel. Flight was delayed .

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

We loved the steward on the plane. He made the night enjoyable

I enjoyed the extra leg room compared to other airlines. The first stewards made my daughter’s birthday special by giving her an extra snack. Then the last one coming home from Chicago to Appleton made our night really enjoyable Thanks for making our trip enjoyable

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

Flight delay was communicated before leaving for airport which caused it to be a non-event. Great flight and crew!

Did not get any refreshments. Crew was very nice but limited. Small seats

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

The pilot would speak it was painfully load a d the crew had to know this! Maybe the were hesitant to tell him. It was just a mediocre experience and I was in Spirit first class!

My experience was terrible. They cancelled my flight twice. They kept delaying it and leading me on, acting like the flight was going to go when it never had a chance. I missed out on valuable family time because of spirit and I won’t be flying with them again.

Was supposed to take off 8:00 last night. Got delayed till 8:00 this morning

It was a no show, so we got put in hotels for a nite. The A320 plane was very modern and flite and crew (if a pilot shows up were fine). Price was very good.

Cheap flight but really uncomfortable. Seat cushions flimsy. Jammed in middle seat when flight is not full. They don’t even give you water

Flight was canceled without warning, gave credit that is hard to access. Awful airline.

Didn’t like that we weren’t even offered a water. And really didn’t like the male flight attendant, he had major attitude. The flight however was good, pilots got us there in time safely.

We liked the woman who worked our gate and waited with us for our plane. We changed gates 3 times. Our flight was supposed to leave at 11:28am. We actually left after 5pm. It was not a good situation. This delay cost us a lot of money.

I didn't order food. I requested a Tomato juice and was given a boody mary mix. The serve needs to warn the customer what their given. It wasn't a huge deal, but I wasted $4.50.

After 2 hrs the flight was canceled. The next flight wasn’t until 4 days away! They wouldn’t book us with other airlines. We ended up driving 15 hrs to get home

Everything you need to know for your flight from Detroit to South Carolina

Information on your arrival and departure airports