$47 Find Cheap Flights from Detroit to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South Carolina departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Detroit to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$110
Myrtle Beach
Myrtle Beach1 stop$119
Greenville
Greenville1 stop$206
Columbia
Columbia2 stops$214
Florence
Florence2 stops$335
Charlotte
Charlotte1 stop$139
Charleston
Charleston1 stop$110
Myrtle Beach
Myrtle Beach1 stop$119
Greenville
Greenville1 stop$206
Columbia
Columbia2 stops$214
Florence
Florence2 stops$335
Charlotte
Charlotte1 stop$139

Book Cheap Detroit to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South Carolina

Wed, Mar 4 - Mon, Mar 9
Spirit Airlines Logo
5:09 am - 4:05 pm
DTW
-
CHS
10h 56m
1 stop
Spirit Airlines Logo
5:00 pm - 12:09 am
CHS
-
DTW
7h 09m
1 stop
$110Spirit Airlines
Mon, Mar 2 - Tue, Mar 3
Spirit Airlines Logo
2:06 pm - 8:39 pm
DTW
-
MYR
6h 33m
1 stop
Spirit Airlines Logo
3:59 pm - 9:54 pm
MYR
-
DTW
5h 55m
1 stop
$119Spirit Airlines
Sat, Feb 21 - Tue, Feb 24
Frontier Logo
10:45 am - 5:48 pm
DTW
-
CLT
7h 03m
1 stop
Frontier Logo
2:46 pm - 8:57 am
CLT
-
DTW
18h 11m
1 stop
$139Frontier
Mon, Feb 23 - Mon, Mar 2
Frontier Logo
10:41 am - 12:32 pm
DTW
-
CLT
1h 51mnonstop
Frontier Logo
4:30 pm - 6:28 pm
CLT
-
DTW
1h 58mnonstop
$140Frontier
Mon, Feb 23 - Mon, Mar 2
Multiple Airlines Logo
10:41 am - 12:32 pm
DTW
-
CLT
1h 51mnonstop
Multiple Airlines Logo
3:12 pm - 9:54 pm
CLT
-
DTW
6h 42m
1 stop
$143Multiple Airlines
Thu, Feb 19 - Thu, Feb 26
Multiple Airlines Logo
5:09 am - 11:32 am
DTW
-
SAV
6h 23m
1 stop
Multiple Airlines Logo
5:17 pm - 11:59 pm
SAV
-
DTW
6h 42m
1 stop
$144Multiple Airlines
Thu, Feb 19 - Mon, Feb 23
Delta Logo
2:21 pm - 8:17 pm
DTW
-
CAE
5h 56m
1 stop
Delta Logo
5:00 pm - 10:15 pm
CAE
-
DTW
5h 15m
1 stop
$274Delta
Fri, Feb 20 - Sat, Feb 28
American Airlines Logo
6:15 am - 5:44 pm
DTW
-
HHH
11h 29m
2 stops
American Airlines Logo
6:20 pm - 11:03 pm
HHH
-
DTW
4h 43m
1 stop
$318American Airlines
Fri, Mar 6 - Sun, Mar 8
American Airlines Logo
2:18 pm - 9:34 pm
DTW
-
AGS
7h 16m
1 stop
American Airlines Logo
4:31 pm - 11:58 pm
AGS
-
DTW
7h 27m
1 stop
$329American Airlines
Wed, Feb 18 - Fri, Feb 27
Delta Logo
5:20 am - 9:35 am
DTW
-
AGS
4h 15m
1 stop
Delta Logo
5:35 am - 10:56 am
AGS
-
DTW
5h 21m
1 stop
$413Delta
Booking Insights

KAYAK's insights & trends for Detroit to South Carolina flights

Get data-powered insights and trends into flights from Detroit to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Detroit Metropolitan Wayne County Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Detroit Metropolitan Wayne County Airport found in the last 72 hours was to Charleston, at $219 round-trip. The most popular route is from Detroit Metropolitan Wayne County Airport (DTW) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $219.

Can I save money by flying with a layover from Detroit Metropolitan Wayne County Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $384 on average.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South Carolina is August, when tickets cost $224 (return) on average. On the other hand, the most expensive months are May and February, when the average cost of round-trip tickets is $397 and $387 respectively.

What’s the cheapest day of the week to fly from Detroit to South Carolina?

The average price of all round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Detroit to South Carolina, you should consider leaving on a Friday and avoid Sundays if you are looking for the best rates. For your return to Detroit, you’ll find the best rates on Thursdays and the most expensive ones on Sundays.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South Carolina, you should book around 3 weeks before departure, which saves you about 28% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$47
Best time to beat the crowds but there is an average 12% increase in price.
Most popular time to fly with an average 6% increase in price.
Flight from Detroit to Savannah

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Detroit to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the afternoon, when round-trip flights cost $299 on average. Morning departures are around 18% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $367.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Detroit to the following destinations at these prices or less: Charlotte $221 one-way - $281 round-trip

Reviews of the top 4 airlines serving from Detroit to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Detroit to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4273 reviews
8.1Boarding
7.0Food
8.0Comfort
8.6Crew
7.5Entertainment
Airline reviews

Flight attendants very hospitable and friendly. Pilot flew a smooth take off and landing.

10.0 ExcellentAnonymous, Feb 2026
MSY - PHX
Read more Southwest reviews

Flight attendants very hospitable and friendly. Pilot flew a smooth take off and landing.

Paid for premium extra leg room but the bin space for rows 1-3 had to go in rows 4-6 and 4-6 had to go to 7-9 because flight attendants have snacks and their luggage upfront. So we pay extra to have to fight thru traffic to get our bags. Only 2nd day of new seating so hope they fix this.

WIFI was great. My selection for seating is an aisle, but during my trip, I never had an aisle seat. If we can get that corrected, I will be thrilled. No snack or drink on this flight.

WIFI was great. My selection for seating is an aisle, but during my trip, I never had an aisle seat. If we can get that corrected, I will be thrilled.

The wifi on the plane is great. The only issue that I have is that I prefer an aisle seat and on my trips this week, I was either in the middle or window. If we can work to secure aisle seating, I will be thrilled. Nice trip.

All good except once again bags took an hour at Midway Airport Happens all the time. Ridiculous

Everything went smoothly and we even arrived a little bit early.

Great vacation. Can't wait till next year for another one.

Great flight but super high price. Glad it was a business trip and not personal

On time. Friendly staff. Took to long to pre bord all the specialty groups. Cramped small plane

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

was sitting in the jet bridge for 10 minutes in -20 degree weather waiting for my bag

Outdated equipment in disrepair, wifi inoperable. Broken seats, taped air vents, generally poor condition, the 717 showed its age and lack of upkeep.

Update to handle the delay was very bad, crews no smiles or welcome or thanks. Don’t care attitude

It would be nice to have some low carb options in the snacks.

I was trying to take 2 one and a half hour one way trips and I experienced almost 20 delays over the course of those two trips. Only a few of them were due to weather the rest was disorganization

No gates avail at DFW so our incoming had to wait 30 mins for a plane to push back because they Had mechanical. We boarded 90 mins delayed and then we had a mechanical. Come on American…do better. Also at my seat the tray table had not been cleaned. Floor had not been cleaned. But captain and flight Att were very picture and apologetic.

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

Everything was OK, the deicing took a long time, our connections were almost missed.

The flight was delayed by 2 hours and we had no food or water or chargers

Cheap, only one short delay. No issues despite bad weather. Able to take a big backpack for free.

Your flight crew and boarding area crew need to have microphone use training. They all hold the microphone right up to their mouths, way to close making understanding them almost impossible. The microphone should be held about 3 to 4 inches away from their mouths. This would provide for much better clarity through the PA system. ‘Eating the mic’ DOES NOT work.

Cancel the ticket on my day that I’m travelling that it was

Spirit cancelled my return flight the day before travel and so I had to book a last minute flight on American Airlines.

Flight was cancelled with no help From spirit or kayak. Please refund asap

Flight was cancelled 2.5 before departure without warning. Staff was rude and lied to us pre-security.

30 minute delay, Also there was a medical emergency on the flight. The flight crew was on top of the situation and assisted the medical professionals that happened to be on the flight.

I didn't eat, so I can't rate the food. Delayed set off was beyond

Everything you need to know for your flight from Detroit to South Carolina

Information on your arrival and departure airports