$44 Find Cheap Flights from Detroit to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to South Carolina departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to South Carolina, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Detroit to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charleston1 stop$121
Myrtle Beach
Myrtle Beach1 stop$119
Greenville
Greenville1 stop$208
Columbia
Columbia1 stop$269
Florence
Florence2 stops$294
Charlotte
Charlotte1 stop$143
Charleston
Charleston1 stop$121
Myrtle Beach
Myrtle Beach1 stop$119
Greenville
Greenville1 stop$208
Columbia
Columbia1 stop$269
Florence
Florence2 stops$294
Charlotte
Charlotte1 stop$143

Book Cheap Detroit to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to South Carolina

Wed, Feb 4 - Wed, Feb 11
Spirit Airlines Logo
5:00 am - 2:42 pm
DTW
-
MYR
9h 42m
1 stop
Spirit Airlines Logo
10:00 am - 12:19 am
MYR
-
DTW
14h 19m
1 stop
$119Spirit Airlines
Mon, Jan 26 - Fri, Jan 30
Spirit Airlines Logo
5:00 am - 4:10 pm
DTW
-
CHS
11h 10m
1 stop
Spirit Airlines Logo
5:05 pm - 12:19 am
CHS
-
DTW
7h 14m
1 stop
$121Spirit Airlines
Mon, Jan 26 - Thu, Jan 29
Spirit Airlines Logo
5:00 am - 4:10 pm
DTW
-
CHS
11h 10m
1 stop
Spirit Airlines Logo
5:05 pm - 12:19 am
CHS
-
DTW
7h 14m
1 stop
$123Spirit Airlines
Sun, Feb 15 - Wed, Feb 18
Multiple Airlines Logo
9:18 am - 7:17 pm
DTW
-
CLT
9h 59m
1 stop
Multiple Airlines Logo
3:12 pm - 9:54 pm
CLT
-
DTW
6h 42m
1 stop
$144Multiple Airlines
Mon, Jan 26 - Sat, Jan 31
Multiple Airlines Logo
5:00 am - 12:22 pm
DTW
-
SAV
7h 22m
1 stop
Multiple Airlines Logo
1:10 pm - 7:37 pm
SAV
-
DTW
6h 27m
1 stop
$145Multiple Airlines
Thu, Feb 12 - Wed, Feb 18
Delta Logo
7:05 am - 9:07 am
DTW
-
CLT
2h 02mnonstop
Delta Logo
5:25 am - 9:30 am
CLT
-
DTW
4h 05m
1 stop
$149Delta
Wed, Mar 18 - Wed, Mar 25
Frontier Logo
9:04 pm - 8:03 am
DTW
-
CLT
10h 59m
1 stop
Frontier Logo
1:59 pm - 8:19 pm
CLT
-
DTW
6h 20m
1 stop
$150Frontier
Fri, Mar 13 - Sun, Mar 15
Delta Logo
2:20 pm - 9:20 pm
DTW
-
CAE
7h 00m
1 stop
Delta Logo
5:34 am - 9:23 am
CAE
-
DTW
3h 49m
1 stop
$269Delta
Wed, Jan 28 - Fri, Jan 30
American Airlines Logo
5:24 pm - 12:20 pm
DTW
-
HHH
18h 56m
2 stops
American Airlines Logo
3:29 pm - 11:33 am
HHH
-
DTW
20h 04m
2 stops
$284American Airlines
Sat, Feb 14 - Sat, Feb 21
American Airlines Logo
10:40 am - 5:44 pm
DTW
-
HHH
7h 04m
2 stops
American Airlines Logo
4:31 pm - 10:16 pm
HHH
-
DTW
5h 45m
1 stop
$288American Airlines
Booking Insights

KAYAK's insights & trends for Detroit to South Carolina flights

Get data-powered insights and trends into flights from Detroit to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Detroit Metropolitan Wayne County Airport to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Detroit Metropolitan Wayne County Airport found in the last 72 hours was to Charleston, at $199 round-trip. The most popular route is from Detroit Metropolitan Wayne County Airport (DTW) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $199.

Can I save money by flying with a layover from Detroit Metropolitan Wayne County Airport to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $434, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Detroit Metropolitan Wayne County Airport to South Carolina is August, when tickets cost $224 (return) on average. On the other hand, the most expensive months are May and April, when the average cost of round-trip tickets is $397 and $383 respectively.

What’s the cheapest day of the week to fly from Detroit to South Carolina?

The average price of all round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Detroit to South Carolina, you should consider leaving on a Friday and avoid Sundays if you are looking for the best rates. For your return to Detroit, you’ll find the best rates on Thursdays and the most expensive ones on Sundays.

How far in advance should I book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Detroit Metropolitan Wayne County Airport to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Detroit Metropolitan Wayne County Airport to South Carolina, you should book around 3 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 15 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$44
Best time to beat the crowds but there is an average 13% increase in price.
Most popular time to fly with an average 6% increase in price.
Flight from Detroit to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Detroit to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Detroit to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Detroit to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Detroit to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $301 on average. Morning departures are around 16% cheaper than evening flights, on average. The most expensive time of day to fly to South Carolina is generally in the evening, which is peak travel time and where the average cost of a ticket is $361.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Detroit to the following destinations at these prices or less: Charlotte $197 one-way - $303 round-trip

Reviews of the top 4 airlines serving from Detroit to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Detroit to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4253 reviews
8.6Crew
7.5Entertainment
8.0Comfort
8.1Boarding
7.0Food
Airline reviews

The staff was very friendly, professional, and courteous. The overall flight was a great experience.

10.0 ExcellentManetta, Jan 2026
MDW - CLT
Read more Southwest reviews

The staff was very friendly, professional, and courteous. The overall flight was a great experience.

The crew canceled the complementary snack and drink in anticipation of turbulence that never materialized. I was counting on the drink (water) to take the the doses of medication - prescribed for my heart condition - that were due during the flight. Since no snack or meal was served on this flight, I cannot rate the food quality. Otherwise, this flight was excellent.

Departure was delayed more than 1/2 hour while we waited for luggage (only) transfer from another flight/plane. Once approved for takeoff, the flight was excellent.

We got exit row seats both flights. Everything was running on time

The flight crew was extremely rude and especially not helpful when our flight was delayed.

Pretty seamless, just a tad bit late in taking off and landing.

Flight was fine other than there was a gate change that I was not notified of. By chance I happened to check my phone and saw the change, otherwise, we would have missed our connecting flight.

Haven’t flown on SW in years. Flight was on time departing and arriving. Served vegan butter onion flavored pretzels which were bad. Coke served was in a tiny paper cup. Crew was not engaging. Felt like they were going through the motions. Old plane, tight seats and no leg room.

Check-in, Boarding and flight were smooth. All the employees and crew was very nice and funny. They gave the kids crayons and workbooks to keep them occupied which was a big win. I’ve flown Southwest many times and that’s the first time I’ve seen that and it is a great addition.

Flight was on time. Wi-fi was a little spotty/slow. Boarding and exit were efficient.

Food is basically Sun Chips, cookies or Cheezits. I had an exit row seat so I had plenty of room. The crew was very nice and efficient. Pilot kept us informed. Pretty good flight.

Air travel sucks. It continues to be awful for all airlines. No shame on delta alone.

It was Delta, but the flight attendants were stressful and disrespectful. I am a diamond member a travel weekly. I have not had a negative thing to share in quite some time. But this was noticeable.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Flight was late from Newark to Atlanta, I asked flight attendant to please let my family of 3 out first when we landed to Atlanta because we were late for our connecting flight to Quito. She didn't and we were late for 5 minutes we couldn't board the plane and spend hours trying to get another flight with customer service for the next day.

I really liked the legroom. I am 6’4”.a at For some reason our seats were not together and using the app to fix it didn’t work. Passengers were nice enough to move for us but you should absolutely ensure a parent sits with their child.

Late delayed flight delays boarding and delays leaving and delays on arrival too. Cramped plane no room no food.

DTW line is too long. The flights from DTW to BWI are always delayed for unknown reasons.

Delta canceled our flight and we had to scramble to find another airline to get home. Phoenix is not a delta hub so they didn’t have another plane. It would have been a red eye though Salt Lake City. Getting in at 5am. No bueno.

This flight was no comparison to our prior flight. I'm thinking it all has to do with the age of the aircraft.

Tell the crew (when boarding) to yell at the imbeciles blocking us from walking up to scan. I promise everyone crowds around and half of us (most the time I’m group 4) have to push our way through. Your staff is awesome, the public - not so much-

Bags took over and hour to come out. Delays due to wind caused rebooking.

The flight was good. We had to spend almost an hour on the tarmac when we arrived in Dallas. Waiting for a gate. What’s the point of arriving early if you have no gate to park at?

Lower WiFi prices; allow us to see our flight on a map; more variety of drink choices.

So excited very proud first of all I wanna thank kayak all updates very professional and fast alart And amazing cabin crew so nice to me they deserve big salute

UGH I HAD TO MISS MY FIRST FLIGHT TO TAMPA CAUSE OF THE 10 MINUTE DELAY OF THE ORLANDO TO MIAMI ONE SO THEY HAD ME GET ANOTHER TICKET. I AM NOT HAPPY AT ALL BECAUSE IT MADE ME MISS MY CONNECTING FLIGHT FROM TAMPA TO LONDON AND FORCED ME TO MISS A DAY AT MY ROOM IN THE UK.

Wish they didnt delay off-boarding for 10 minutes so i could connect to my flight from miami to tampa

We experienced gate changes and a long delay. My seat was dirty when I boarded and I had to use wipes to clean it myself. There was an unpleasant and overpowering cleaning product scent on the plane as well that lingered through the flight.

Seats were much more cramped then on the 737. Narrower and rows closer together. Flight was absolutely packed and the plugs under the seats didn't work. Was forced to check my bag even though previous flight had no issue with it.

It was fine. My connection in Charlotte to go to WPB was too late and I had to spend the night in the Charlotte Airport in the mini suites.

Your flight crew and boarding area crew need to have microphone use training. They all hold the microphone right up to their mouths, way to close making understanding them almost impossible. The microphone should be held about 3 to 4 inches away from their mouths. This would provide for much better clarity through the PA system. ‘Eating the mic’ DOES NOT work.

Cancel the ticket on my day that I’m travelling that it was

Spirit cancelled my return flight the day before travel and so I had to book a last minute flight on American Airlines.

Flight was cancelled with no help From spirit or kayak. Please refund asap

Flight was cancelled 2.5 before departure without warning. Staff was rude and lied to us pre-security.

30 minute delay, Also there was a medical emergency on the flight. The flight crew was on top of the situation and assisted the medical professionals that happened to be on the flight.

I didn't eat, so I can't rate the food. Delayed set off was beyond

It was better than expected. But there were two delays in taking off.

The pilot would speak it was painfully load a d the crew had to know this! Maybe the were hesitant to tell him. It was just a mediocre experience and I was in Spirit first class!

My experience was terrible. They cancelled my flight twice. They kept delaying it and leading me on, acting like the flight was going to go when it never had a chance. I missed out on valuable family time because of spirit and I won’t be flying with them again.

Everything you need to know for your flight from Detroit to South Carolina

Information on your arrival and departure airports