DTW - LSE

$362 Find Cheap Flights from Detroit to La Crosse

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to La Crosse departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to La Crosse

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to La Crosse, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to La Crosse, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$498
American Airlines
Sat 3/14Wed 3/18
DTW - LSE • 1 stop
Cheapest one-way
$362
American Airlines
Wed 11/19
DTW - LSE • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to La Crosse!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Detroit to La Crosse (DTW-LSE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to La Crosse that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to La Crosse

Sat, Mar 14 - Wed, Mar 18
American Airlines Logo
8:42 am - 2:18 pmDTW-LSE
6h 36m1 stop
American Airlines Logo
4:46 pm - 8:59 pmLSE-DTW
3h 13m1 stop
$498American Airlines
Find Deal
Sat, Mar 14 - Wed, Mar 18
American Airlines Logo
12:07 pm - 9:40 pmDTW-LSE
10h 33m2 stops
American Airlines Logo
4:46 pm - 8:59 pmLSE-DTW
3h 13m1 stop
$504American Airlines
Find Deal
Sat, Mar 14 - Wed, Mar 18
American Airlines Logo
12:07 pm - 9:40 pmDTW-LSE
10h 33m2 stops
American Airlines Logo
1:03 pm - 12:13 amLSE-DTW
10h 10m2 stops
$509American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
6:45 am - 9:29 amDTW-LSE
3h 44m1 stop
American Airlines Logo
6:00 am - 12:10 pmLSE-DTW
5h 10m1 stop
$516American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
12:45 pm - 3:40 pmDTW-LSE
3h 55m1 stop
American Airlines Logo
6:00 am - 2:52 pmLSE-DTW
7h 52m2 stops
$522American Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16
American Airlines Logo
10:57 am - 10:02 pmDTW-LSE
12h 05m2 stops
American Airlines Logo
6:00 am - 4:41 pmLSE-DTW
9h 41m2 stops
$527American Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
6:36 pm - 11:49 pmDTW-LSE
6h 13m1 stop
American Airlines Logo
6:13 pm - 11:52 pmLSE-DTW
4h 39m1 stop
$540American Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
6:45 am - 9:20 amDTW-LSE
3h 35m1 stop
American Airlines Logo
9:50 am - 9:51 pmLSE-DTW
11h 01m2 stops
$546American Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
American Airlines Logo
7:10 am - 5:43 pmDTW-LSE
11h 33m2 stops
American Airlines Logo
6:00 am - 4:07 pmLSE-DTW
9h 07m2 stops
$551American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Detroit to La Crosse flights

Get data-powered insights and trends into flights from Detroit to La Crosse to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Detroit Metropolitan Wayne County Airport and La Crosse?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Detroit Metropolitan Wayne County Airport to La Crosse.

There is just one airline that flies from Detroit Metropolitan Wayne County Airport to La Crosse direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $414.

Good to know

Cheapest flight$362
Flight from Detroit to La Crosse

When to book flights from Detroit to La Crosse

Are your dates flexible? Find out the best times to travel from Detroit to La Crosse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Detroit to La Crosse flights

  • What is the cheapest flight from Detroit Metropolitan Wayne County Airport to La Crosse?

    In the last 3 days, the lowest price for a flight from Detroit Metropolitan Wayne County Airport to La Crosse was $362 for a one-way ticket and $498 for a round-trip.

  • Do I need a passport to fly between Detroit and La Crosse?

    A passport is not required to fly from Detroit to La Crosse.

  • Which airports will I be using when flying from Detroit to La Crosse?

    When flying out of Detroit you will be using Detroit Metropolitan Wayne County. You will be landing at La Crosse, also known as La Crosse.

  • Which aircraft models fly most regularly from Detroit to La Crosse?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Detroit to La Crosse?

    oneworld is the only airline alliance operating flights between Detroit and La Crosse.

  • How does KAYAK find such low prices on flights from Detroit to La Crosse?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to La Crosse.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to La Crosse?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to La Crosse from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to La Crosse?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to La Crosse with an airline and back to Detroit with another airline. Booking your flights between Detroit and LSE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to La Crosse?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to La Crosse from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Detroit to La Crosse

 
See real verified KAYAK customer reviews for airlines flying from Detroit to La Crosse. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to La Crosse? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11030 reviews
7.2Comfort
7.5Boarding
6.4Food
6.9Entertainment
8.0Crew
Airline reviews

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

8.0 ExcellentKohMeng, Oct 2025DFW - LAX
Read more American Airlines reviews

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

Wish a flight with more than 2 hours with some snack rather than just cookie/biscuit.

The flight attendant, a black woman with curly hair who sat near Row 21, was wonderful and kind.

It was good..clean, comfy seat. Friendly warm welcoming crew. Was able to check my cabin luggage at the gate which I was able to pickup in a decent time from baggage claim. The app gave all updates from delays to baggage claim info. Overall smooth flight.

Flight was delayed leaving Dallas. Arrived about 2 hours later than scheduled.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

We are too tired and frustrated to comment politely at this point

Terrible. Our luggage was delayed and couldn’t be delivered for several days. We got bad information from the airline agents at baggage claim. We had to pick up our car so we wouldn’t be charged for an extra day. We got lost in the maze of airport parking. The baggage claim agents didn’t offer us any compensation for our extra time and expense. We are tired, hungry and very frustrated.

The flight was flawless and we even arrived between 20 and 25 minutes early!

The only thing to like was that we eventually got to our destination

Everything you need to know for your flight from Detroit to La Crosse

Information on your arrival and departure airports

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