DTW - LSE

$488 Find Cheap Flights from Detroit to La Crosse

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to La Crosse departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to La Crosse

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to La Crosse, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to La Crosse, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$488
American Airlines
Thu 2/26Thu 3/5
DTW - LSE • 1 stop
Cheapest one-way
Multiple Airlines
Thu 1/29
DTW - LSE • multi-stop
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We hope you love your trip to La Crosse!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Detroit to La Crosse (DTW-LSE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to La Crosse that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to La Crosse

Thu, Feb 26 - Thu, Mar 5
American Airlines Logo
1:02 pm - 5:59 pm
DTW
-
LSE
5h 57m
1 stop
American Airlines Logo
5:20 am - 9:56 am
LSE
-
DTW
3h 36m
1 stop
$488American Airlines
Thu, Feb 26 - Thu, Mar 5
American Airlines Logo
5:45 am - 11:01 am
DTW
-
LSE
6h 16m
1 stop
American Airlines Logo
5:20 am - 2:57 pm
LSE
-
DTW
8h 37m
2 stops
$494American Airlines
Thu, Feb 26 - Thu, Mar 5
American Airlines Logo
10:11 am - 5:59 pm
DTW
-
LSE
8h 48m
2 stops
American Airlines Logo
5:20 am - 2:57 pm
LSE
-
DTW
8h 37m
2 stops
$499American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
5:45 am - 11:01 am
DTW
-
LSE
6h 16m
1 stop
American Airlines Logo
5:20 am - 12:32 pm
LSE
-
DTW
6h 12m
1 stop
$537American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
1:02 pm - 5:59 pm
DTW
-
LSE
5h 57m
1 stop
American Airlines Logo
5:20 am - 2:57 pm
LSE
-
DTW
8h 37m
2 stops
$543American Airlines
Thu, Feb 12 - Sat, Feb 14
American Airlines Logo
10:11 am - 5:59 pm
DTW
-
LSE
8h 48m
2 stops
American Airlines Logo
5:20 am - 2:57 pm
LSE
-
DTW
8h 37m
2 stops
$548American Airlines
Tue, Feb 17 - Fri, Feb 20
American Airlines Logo
5:45 am - 9:18 am
DTW
-
LSE
4h 33m
1 stop
American Airlines Logo
6:29 pm - 9:56 am
LSE
-
DTW
14h 27m
1 stop
$758American Airlines
Tue, Feb 17 - Fri, Feb 20
American Airlines Logo
1:03 pm - 11:36 pm
DTW
-
LSE
11h 33m
2 stops
American Airlines Logo
6:29 pm - 9:56 am
LSE
-
DTW
14h 27m
1 stop
$764American Airlines
Tue, Jun 2 - Thu, Jun 4
American Airlines Logo
12:52 pm - 4:55 pm
DTW
-
LSE
5h 03m
1 stop
American Airlines Logo
11:31 am - 4:27 pm
LSE
-
DTW
3h 56m
1 stop
$811American Airlines
Tue, Jun 2 - Thu, Jun 4
American Airlines Logo
4:08 pm - 11:59 pm
DTW
-
LSE
8h 51m
2 stops
American Airlines Logo
6:00 am - 12:21 pm
LSE
-
DTW
5h 21m
1 stop
$817American Airlines
Booking Insights

Good to know

Cheapest flight$488
Flight from Detroit to La Crosse

When to book flights from Detroit to La Crosse

Are your dates flexible? Find out the best times to travel from Detroit to La Crosse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Detroit to La Crosse flights

  • What is the cheapest flight from Detroit Metropolitan Wayne County Airport to La Crosse?

    In the last 3 days, the lowest price for a flight from Detroit Metropolitan Wayne County Airport to La Crosse was $488 for a round-trip ticket.

  • Do I need a passport to fly between Detroit and La Crosse?

    A passport is not required to fly from Detroit to La Crosse.

  • Which airports will I be using when flying from Detroit to La Crosse?

    When flying out of Detroit you will be using Detroit Metropolitan Wayne County. You will be landing at La Crosse, also known as La Crosse.

  • Which aircraft models fly most regularly from Detroit to La Crosse?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Detroit to La Crosse?

    oneworld is the only airline alliance operating flights between Detroit and La Crosse.

  • How does KAYAK find such low prices on flights from Detroit to La Crosse?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to La Crosse.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to La Crosse?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to La Crosse from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to La Crosse?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to La Crosse with an airline and back to Detroit with another airline. Booking your flights between Detroit and LSE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to La Crosse?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to La Crosse from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Detroit to La Crosse

 
See real verified KAYAK customer reviews for airlines flying from Detroit to La Crosse. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to La Crosse? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11206 reviews
8.0Crew
7.5Boarding
6.9Entertainment
7.2Comfort
6.4Food
Airline reviews

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

4.0 OkayAllison, Jan 2026
MKE - DFW
Read more American Airlines reviews

Crew was helpful and cheerful especially when they had no refreshments to work with. The plane was never serviced and had nothing but limited water and coffee onboard. For the price point, a concern of services.

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

Flight was canceled. I asked to be rerouted to OKC and then took an Uber.

AA did not allow to board a flight because my connecting flight from DFW had been canceled. I got on another flight to another city. No service on the plane and I did not use their entertainment system.

On time on a day with lots of weather cancellations on other flights. Thank you for getting me home during a winter storm!

Don't change gate multiple times make people run across the airport. Announce delays in a timely manner. Have maintenance crew ready. Don't delay and keep passengers on the plane for 3 hrs. on tarmac.

The plane was experiencing problems with the HVAC system, it was very cold in the front of the plane and very hot in the back.

The attendants were kind and helpful. A sugar-free drink would have been very welcome.

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

one crew said "he" didn't serve double alcohol drinks for travelers in exit rows. crew on prior flight did. Is this a AA rule, and the prior crew was being nice? Also, I think we deserve more than a 25% refund for losing first class seats when rescheduling a flight due to weather

Everything you need to know for your flight from Detroit to La Crosse

Information on your arrival and departure airports