DTW - LSE

$278 Find Cheap Flights from Detroit to La Crosse

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Detroit to La Crosse departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to La Crosse

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to La Crosse, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Detroit to La Crosse, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$278
American Airlines
Fri 4/10Sun 4/12
DTW - LSE • 1 stop
Cheapest one-way
$354
American Airlines
Sun 3/22
DTW - LSE • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Detroit and La Crosse. You'll need at least 1 connection.
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We hope you love your trip to La Crosse!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Detroit to La Crosse (DTW-LSE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Detroit to La Crosse that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Detroit to La Crosse

Fri, Apr 10 - Sun, Apr 12
American Airlines Logo
6:00 am - 9:35 am
DTW
-
LSE
4h 35m
1 stop
American Airlines Logo
6:37 pm - 11:25 pm
LSE
-
DTW
3h 48m
1 stop
$278American Airlines
Fri, Apr 10 - Sun, Apr 12
American Airlines Logo
3:30 pm - 11:54 pm
DTW
-
LSE
9h 24m
2 stops
American Airlines Logo
6:37 pm - 12:45 am
LSE
-
DTW
5h 08m
1 stop
$284American Airlines
Tue, Apr 14 - Wed, Apr 29
American Airlines Logo
6:00 am - 9:35 am
DTW
-
LSE
4h 35m
1 stop
American Airlines Logo
6:37 pm - 11:25 pm
LSE
-
DTW
3h 48m
1 stop
$298American Airlines
Tue, Apr 14 - Wed, Apr 29
American Airlines Logo
1:06 pm - 11:54 pm
DTW
-
LSE
11h 48m
2 stops
American Airlines Logo
6:37 pm - 12:45 am
LSE
-
DTW
5h 08m
1 stop
$304American Airlines
Tue, Apr 14 - Wed, Apr 29
American Airlines Logo
1:06 pm - 11:54 pm
DTW
-
LSE
11h 48m
2 stops
American Airlines Logo
10:05 am - 10:28 pm
LSE
-
DTW
11h 23m
2 stops
$424American Airlines
Sat, Mar 28 - Mon, Mar 30
American Airlines Logo
5:45 am - 11:02 am
DTW
-
LSE
6h 17m
1 stop
American Airlines Logo
6:29 pm - 12:31 am
LSE
-
DTW
5h 02m
1 stop
$578American Airlines
Sat, Mar 28 - Mon, Mar 30
American Airlines Logo
5:45 am - 11:02 am
DTW
-
LSE
6h 17m
1 stop
American Airlines Logo
11:34 am - 11:03 pm
LSE
-
DTW
10h 29m
2 stops
$634American Airlines
Sat, Mar 28 - Mon, Mar 30
American Airlines Logo
11:11 am - 11:36 pm
DTW
-
LSE
13h 25m
2 stops
American Airlines Logo
5:09 am - 4:48 pm
LSE
-
DTW
10h 39m
2 stops
$919American Airlines
Booking Insights

Good to know

Cheapest flight$278
Flight from Detroit to La Crosse

When to book flights from Detroit to La Crosse

Are your dates flexible? Find out the best times to travel from Detroit to La Crosse based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Detroit to La Crosse flights

  • What is the cheapest flight from Detroit Metropolitan Wayne County Airport to La Crosse?

    In the last 3 days, the lowest price for a flight from Detroit Metropolitan Wayne County Airport to La Crosse was $354 for a one-way ticket and $278 for a round-trip.

  • Do I need a passport to fly between Detroit and La Crosse?

    A passport is not required to fly from Detroit to La Crosse.

  • Which airports will I be using when flying from Detroit to La Crosse?

    When flying out of Detroit you will be using Detroit Metropolitan Wayne County. You will be landing at La Crosse, also known as La Crosse.

  • Which aircraft models fly most regularly from Detroit to La Crosse?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Detroit to La Crosse?

    oneworld is the only airline alliance operating flights between Detroit and La Crosse.

  • How does KAYAK find such low prices on flights from Detroit to La Crosse?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Detroit to La Crosse.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Detroit to La Crosse?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to La Crosse from Detroit is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Detroit to La Crosse?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to La Crosse with an airline and back to Detroit with another airline. Booking your flights between Detroit and LSE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Detroit to La Crosse?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to La Crosse from Detroit up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Detroit to La Crosse

 
See real verified KAYAK customer reviews for airlines flying from Detroit to La Crosse. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Detroit to La Crosse? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11468 reviews
7.5Boarding
7.9Crew
7.2Comfort
6.9Entertainment
6.4Food
Airline reviews

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

4.0 OkaySean, Mar 2026
PSP - DFW
Read more American Airlines reviews

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

After changing the departure gate 5 times making us mo e from one side of the airport to the other and then back the flight was delayed nearly 2 hours. The male flight attendant had a bad attitude with the guest being condescending, disrespectful with people who were already on edge.

Easy boarding. Rows are smaller but that may be an older and bigger me now :)

It would have been nice if American tried to care.

American Airlines did everything they could with the high Spring Break crowd. I was frustrated to be changed from 1st class to a middle seat at the back of the plane. This has happened before, not sure booking 1st class and paying the extra actually works.

I booked 1st class, my flights were changed and I was sitting in the middle at the back of the plane. A far cry from the 1st class I purchased for my flights. I am grateful I arrived on time.

There was no beverage service and the only time I saw a crew member walk through the cabin is when we were preparing to land.

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

Flights were constantly delayed. CRW took 50 minutes to get bags

Flight has been delayed every time I've ever taken it. Seats uncomfortable. Children behind me yelling the entire flight. Some of this is out of their control but overall just consistently not a great experience.

Everything you need to know for your flight from Detroit to La Crosse

Information on your arrival and departure airports

Detroit (DTW)
La Crosse (LSE)