$456 Find Cheap Flights from Fort Myers to Panama

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Fort Myers to Panama departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Book Cheap Fort Myers to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Fort Myers to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Fort Myers to Panama

Sat, Feb 7 - Mon, Feb 9
United Airlines Logo
7:00 am - 2:45 pm
RSW
-
PTY
7h 45m1 stop
United Airlines Logo
4:41 pm - 10:45 am
PTY
-
RSW
18h 04m1 stop
$456United Airlines
Sat, Feb 7 - Mon, Feb 9
United Airlines Logo
11:48 am - 2:45 pm
RSW
-
PTY
26h 57m1 stop
United Airlines Logo
4:41 pm - 10:45 am
PTY
-
RSW
18h 04m1 stop
$465United Airlines
Wed, Jan 21 - Mon, Jan 26
United Airlines Logo
7:00 am - 7:38 pm
RSW
-
PTY
12h 38m1 stop
United Airlines Logo
4:41 pm - 8:28 pm
PTY
-
RSW
27h 47m1 stop
$485United Airlines
Thu, Mar 12 - Mon, Mar 16
United Airlines Logo
6:45 am - 6:38 pm
RSW
-
PTY
12h 53m1 stop
United Airlines Logo
3:41 pm - 10:42 am
PTY
-
RSW
18h 01m1 stop
$491United Airlines
Wed, Jan 21 - Mon, Jan 26
American Airlines Logo
6:35 pm - 1:27 pm
RSW
-
PTY
18h 52m2 stops
American Airlines Logo
2:27 pm - 12:22 pm
PTY
-
RSW
21h 55m2 stops
$500American Airlines
Thu, Feb 19 - Mon, Feb 23
American Airlines Logo
4:24 pm - 3:15 pm
RSW
-
PTY
22h 51m2 stops
American Airlines Logo
4:05 pm - 4:00 pm
PTY
-
RSW
23h 55m2 stops
$529American Airlines
Thu, Mar 12 - Mon, Mar 16
American Airlines Logo
7:42 pm - 2:22 pm
RSW
-
PTY
19h 40m2 stops
American Airlines Logo
3:13 pm - 4:01 pm
PTY
-
RSW
23h 48m2 stops
$629American Airlines
Thu, Mar 12 - Mon, Mar 16
American Airlines Logo
4:19 pm - 2:22 pm
RSW
-
PTY
23h 03m2 stops
American Airlines Logo
3:13 pm - 4:01 pm
PTY
-
RSW
23h 48m2 stops
$640American Airlines
Wed, Jan 21 - Mon, Jan 26
Multiple Airlines Logo
7:45 pm - 8:11 am
RSW
-
PTY
36h 26m2 stops
Multiple Airlines Logo
8:57 am - 4:35 pm
PTY
-
RSW
7h 38m1 stop
$972Multiple Airlines
Mon, Dec 29 - Sun, Jan 4
Delta Logo
5:35 am - 8:00 pm
RSW
-
PTY
14h 25m1 stop
Delta Logo
8:00 am - 10:57 pm
PTY
-
RSW
14h 57m1 stop
$990Delta
Booking Insights

KAYAK's insights & trends for Fort Myers to Panama flights

Get data-powered insights and trends into flights from Fort Myers to Panama to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Fort Myers and Panama?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Fort Myers to Panama.

There is just one airline that flies from Fort Myers to Panama direct and that is Delta. The best round-trip deal found from Delta for the route is to Panama City (PTY) and costs $467.

Good to know

Cheapest flight$456
Flight from Fort Myers to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Fort Myers to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Fort Myers to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Fort Myers to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Fort Myers to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Fort Myers to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Fort Myers to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Fort Myers to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Fort Myers to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the morning, when round-trip flights cost $545 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $545.

Reviews of the top airline flying from Fort Myers to Panama

 
Need help choosing which airline to fly with from Fort Myers to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8007 reviews
8.1Boarding
7.9Entertainment
8.5Crew
7.3Food
7.9Comfort
Airline reviews

The food is terrible. The staff is wonderful. Comfort is good.

10.0 ExcellentRonda, Dec 2025
JAX - JFK
Read more Delta reviews

The food is terrible. The staff is wonderful. Comfort is good.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Non stop on long haul is the way to go. Great experience

The boarding process needs to be refined. Sometimes the gate crew call out the boarding zone, and then flip to the monitor to show which zones are boarding. So unless everyone is gathered around to see the monitor there is usually confusion as wi which zones are boarding.

Passengers need to check in big baggage instead of bringing on the plane. That cause inconvenience for everyone. Otherwise flight was good.

Really low quality food especially for an international flight. The crew also was surprisingly unpleasant except couple of ladies. I know we were not in first class but that’s no reason to treat customers as less.

Everything you need to know for your flight from Fort Myers to Panama

Information on your arrival and departure airports