$202 Find Cheap Flights from Gainesville to South Carolina - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Gainesville to South Carolina departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Gainesville to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Myrtle Beach
Myrtle Beach1 stop$397
Greenville
Greenville1 stop$397
Charlotte
Charlottenonstop$403
Myrtle Beach
Myrtle Beach1 stop$397
Greenville
Greenville1 stop$397
Charlotte
Charlottenonstop$403

Book Cheap Gainesville to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Gainesville to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Gainesville to South Carolina

Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
4:39 pm - 9:08 pm
GNV
-
MYR
4h 29m
1 stop
American Airlines Logo
5:45 pm - 9:50 pm
MYR
-
GNV
4h 05m
1 stop
$378American Airlines
Fri, Sep 11 - Fri, Sep 18
American Airlines Logo
4:39 pm - 9:08 pm
GNV
-
MYR
4h 29m
1 stop
American Airlines Logo
5:45 pm - 9:50 pm
MYR
-
GNV
4h 05m
1 stop
$397American Airlines
Wed, Aug 19 - Sat, Aug 22
American Airlines Logo
2:51 pm - 6:36 pm
GNV
-
GSP
3h 45m
1 stop
American Airlines Logo
5:19 pm - 9:45 pm
GSP
-
GNV
4h 26m
1 stop
$397American Airlines
Sat, Sep 5 - Sun, Sep 6
American Airlines Logo
5:45 am - 7:34 am
GNV
-
CLT
1h 49mnonstop
American Airlines Logo
5:15 pm - 6:56 pm
CLT
-
GNV
1h 41mnonstop
$403American Airlines
Sat, Sep 5 - Sun, Sep 6
American Airlines Logo
5:45 am - 7:34 am
GNV
-
CLT
1h 49mnonstop
American Airlines Logo
5:15 pm - 6:56 pm
CLT
-
GNV
1h 41mnonstop
$403American Airlines
Sat, Sep 12 - Tue, Sep 15
American Airlines Logo
7:33 am - 9:24 am
GNV
-
CLT
1h 51mnonstop
American Airlines Logo
8:10 pm - 9:50 pm
CLT
-
GNV
1h 40mnonstop
$403American Airlines
Wed, Sep 2 - Tue, Sep 8
American Airlines Logo
5:45 am - 7:34 am
GNV
-
CLT
1h 49mnonstop
American Airlines Logo
8:10 pm - 9:51 pm
CLT
-
GNV
1h 41mnonstop
$403American Airlines
Wed, Dec 16 - Wed, Dec 23
American Airlines Logo
8:00 pm - 9:50 pm
GNV
-
CLT
1h 50mnonstop
American Airlines Logo
5:58 pm - 7:37 pm
CLT
-
GNV
1h 39mnonstop
$403American Airlines
Sun, Aug 23 - Mon, Sep 7
Delta Logo
7:01 pm - 10:59 pm
GNV
-
GSP
3h 58m
1 stop
Delta Logo
6:00 am - 9:23 am
GSP
-
GNV
3h 23m
1 stop
$407Delta
Thu, Aug 20 - Sun, Aug 23
Delta Logo
3:41 pm - 8:32 pm
GNV
-
GSP
4h 51m
1 stop
Delta Logo
5:46 am - 9:23 am
GSP
-
GNV
3h 37m
1 stop
$417Delta
Booking Insights

KAYAK's insights & trends for Gainesville to South Carolina flights

Get data-powered insights and trends into flights from Gainesville to South Carolina to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Gainesville to South Carolina?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Gainesville to South Carolina were found on American Airlines ($397) and Delta ($407).

Find deals

Good to know

Cheapest flight

$202
Flight from Gainesville to Charlotte

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Gainesville to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Gainesville to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Gainesville to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Gainesville to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Gainesville to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Gainesville to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Gainesville to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Gainesville to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Gainesville to the following destinations at these prices or less: Charlotte $347 one-way - $446 round-trip

Reviews of the top airline flying from Gainesville to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Gainesville to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Gainesville to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.1
American AirlinesOverall score based on 11845 reviews
7.9Crew
6.4Food
6.8Entertainment
7.5Boarding
7.2Comfort
Airline reviews

Quick flight. No time to stress over it. Over before it begins.

10.0 ExcellentSergio, Jul 2026
GNV - MIA
Read more American Airlines reviews

Quick flight. No time to stress over it. Over before it begins.

Very turbulent flight, no drinks, very little service, unorganized boarding, gate changed multiple times

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

why would I bother with this airline and pick seats when I am asked to move for a weight imbalance

I appreciated that it was on time, safe and professional. I didn’t like that I wasn’t in a place where I had a window at my window seat. It would have been nice to know that in advance. If it was mentioned in the ticketing, I didn’t notice it.

Poor seat in rear of aircraft Food at Admiral’s Club Terminal D at DFW inedible

Multiple gate changes and significant delay leaving DFW. Made for a late arrival

For the price of the ticket you get nothing. The plane had 1 bathroom in the back and when the flight attendant did service no one could use it. No announcement just was told to go back to my seat. Ridiculous and rude.

In-flight Wi-Fi didn’t work and the flight was 25 minutes late. The Embraer plane I was on was pretty old and the tray table was broken.

American Airlines no longer has Bischoff biscuits. This is intolerable.

Everything you need to know for your flight from Gainesville to South Carolina

Information on your arrival and departure airports

Gainesville (GNV)