GSP - ECP

$289 Find Cheap Flights from Greenville to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to Panama City departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Greenville to Panama City, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$289
Overall average: $361
Delta
Tue 3/17Tue 3/24
GSP - ECP • 1 stop
Cheapest one-way
$279
Delta
Tue 2/3
GSP - ECP • 1 stop
Top airlines
Delta
Cheapest • from $289 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
December
Cheapest • 30% price drop
May
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Greenville to Panama City (GSP-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to Panama City

Tue, Mar 17 - Tue, Mar 24
Delta Logo
5:40 am - 8:40 am
GSP
-
ECP
4h 00m
1 stop
Delta Logo
7:05 am - 11:05 am
ECP
-
GSP
3h 00m
1 stop
$289Delta
Fri, Mar 20 - Tue, Mar 24
Delta Logo
6:45 am - 8:40 am
GSP
-
ECP
2h 55m
1 stop
Delta Logo
6:00 am - 11:05 am
ECP
-
GSP
4h 05m
1 stop
$308Delta
Mon, Apr 6 - Mon, Apr 13
Delta Logo
7:59 pm - 11:04 pm
GSP
-
ECP
4h 05m
1 stop
Delta Logo
6:46 pm - 11:56 pm
ECP
-
GSP
4h 10m
1 stop
$318Delta
Sun, Apr 12 - Thu, Apr 16
Southwest Logo
6:30 am - 9:10 am
GSP
-
ECP
3h 40m
1 stop
Southwest Logo
9:55 am - 8:55 pm
ECP
-
GSP
10h 00m
2 stops
$323Southwest
Tue, Mar 17 - Fri, Mar 20
Delta Logo
5:40 am - 10:23 am
GSP
-
ECP
5h 43m
1 stop
Delta Logo
6:00 am - 11:05 am
ECP
-
GSP
4h 05m
1 stop
$328Delta
Sun, Mar 15 - Sat, Mar 28
Delta Logo
7:59 pm - 11:04 pm
GSP
-
ECP
4h 05m
1 stop
Delta Logo
5:30 pm - 11:54 pm
ECP
-
GSP
5h 24m
1 stop
$331Delta
Tue, Mar 17 - Wed, Mar 25
United Airlines Logo
6:30 am - 1:14 pm
GSP
-
ECP
7h 44m
1 stop
United Airlines Logo
10:24 am - 11:59 pm
ECP
-
GSP
12h 35m
2 stops
$336United Airlines
Sun, Apr 12 - Thu, Apr 16
Southwest Logo
6:30 am - 12:15 pm
GSP
-
ECP
6h 45m
2 stops
Southwest Logo
9:55 am - 8:55 pm
ECP
-
GSP
10h 00m
2 stops
$338Southwest
Tue, Mar 17 - Mon, Mar 23
Delta Logo
11:40 am - 11:04 pm
GSP
-
ECP
12h 24m
2 stops
Delta Logo
6:43 pm - 11:54 pm
ECP
-
GSP
4h 11m
1 stop
$348Delta
Thu, Mar 19 - Tue, Mar 24
Delta Logo
7:59 pm - 8:40 am
GSP
-
ECP
13h 41m
1 stop
Delta Logo
7:05 am - 11:05 am
ECP
-
GSP
3h 00m
1 stop
$358Delta
Booking Insights

KAYAK's insights & trends for Greenville to Panama City flights

Get data-powered insights and trends into flights from Greenville to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Greenville to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Greenville to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Greenville to Panama City is December, where tickets cost $278 (return) on average. On the other hand, the most expensive months are October and November, where the average cost of round-trip tickets is $756 and $556 respectively.

Good to know

Low seasonOctober
Cheapest flight$279
Best time to beat the crowds but there is an average 90% increase in price.
Most popular time to fly and prices are also 10% lower on average.
Flight from Greenville to Panama City

When to book flights from Greenville to Panama City

Are your dates flexible? Find out the best times to travel from Greenville to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Greenville to Panama City

  • What is the cheapest flight from Greenville to Panama City?

    In the last 3 days, the lowest price for a flight from Greenville to Panama City was $279 for a one-way ticket and $289 for a round-trip.

  • Do I need a passport to fly between Greenville and Panama City?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Greenville to Panama City?

    When flying out of Greenville you will be using Greenville. You will be landing at Panama City, also known as Panama City NW Florida Beaches.

  • Which aircraft models fly most regularly from Greenville to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Greenville to Panama City?

    SkyTeam is the only airline alliance operating flights between Greenville and Panama City.

  • How does KAYAK find such low prices on flights from Greenville to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Greenville with another airline. Booking your flights between Greenville and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Greenville to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Greenville to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Greenville to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8128 reviews
7.2Food
7.9Comfort
8.1Boarding
7.8Entertainment
8.5Crew
Airline reviews

I've flown several other airlines, and Delta is really on top on things.

10.0 ExcellentBob, Jan 2026
SCL - MIA
Read more Delta reviews

I've flown several other airlines, and Delta is really on top on things.

The flight was delayed and oversold. I volunteered to give up my seat for compensation. Thinking I could get a good night's sleep instead of arriving home at 2 am. It took over an hour to get the new reservation confirmed, three different gate attendants, and two red coats. It took even longer to confirm the overnight hotel, and when I arrived, the line was 45 minutes long, with two people checking in, and at least 15 people slowly, very slowly—no food except frozen convenience food, no coupon for food from airlines. Slept, headed back to the airport, and that flight had an equipment change and a gate change just as they were about to board. It took an additional hour to board as they cleaned the plane from storage.

Comfort Plus seat 11E seemed smaller than prior flights. The movie selection is good. Watched most of the most recent Tron movie. I'll watch the remaining part later as my movie is saved in the Delta Seatback Experience.

Delta is a good airline. I've never had an issue with Delta. I'll continue to fly with them until they show me that I shouldn't.

Flight was operated by Virgin Atlantic and it was up to their usual high standard. Minor grips about some issues, but they are really first world issues and as a whole, was an excellent flight.

Original flight was cancelled and when i was rebooked by the airline, they couldn't seat me in the same type of seat as I had originally booked (went from window/aisle to middle/middle and one was a bulkhead seat, and other wasn't in the same class)

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything you need to know for your flight from Greenville to Panama City

Information on your arrival and departure airports