GSP - SFO

$140 Find Cheap Flights from Greenville to San Francisco - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$319
Typical prices: $432-$676
Delta
Mon 12/3Fri 12/7
GSP - SFO • 1 stop
Cheapest one-way
$140
Typical prices: $197-$355
Multiple Airlines
Thu 1/18
GSP - SFO • 3 stops
Nonstop flights
There are currently no direct flights between Greenville and San Francisco. You'll need to take a connecting flight to reach the destination.
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Insights
When to travel
Cheapest • 11% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $415 (round-trip)
Shortest trip • 7h 27m (one-way)
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Insights
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Flight Deals

Cheap Flights from Greenville to San Francisco (GSP-SFO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to San Francisco

Thu, Dec 3 - Mon, Dec 7
Delta Logo
5:40 am - 10:35 amGSP  Greenville-SFO San Francisco
7h 55m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:59 pm - 11:13 amSFO  San Francisco-GSP Greenville
9h 14m1 stop Atlanta Hartsfield-Jackson
$319Delta
Wed, Dec 9 - Wed, Dec 16
United Airlines Logo
7:48 pm - 1:30 amGSP  Greenville-SFO San Francisco
8h 42m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
5:00 am - 3:12 pmSFO  San Francisco-GSP Greenville
7h 12m1 stop Denver Intl
$319United Airlines
Fri, Dec 4 - Thu, Dec 10
American Airlines Logo
5:17 pm - 10:31 pmGSP  Greenville-SFO San Francisco
8h 14m1 stop Dallas/Fort Worth
American Airlines Logo
5:35 am - 4:23 pmSFO  San Francisco-GSP Greenville
7h 48m1 stop Dallas/Fort Worth
$339American Airlines
Wed, Dec 9 - Wed, Dec 16
Southwest Logo
8:05 am - 1:50 pmGSP  Greenville-SFO San Francisco
8h 45m1 stop Baltimore/Washington
Southwest Logo
7:15 am - 8:50 pmSFO  San Francisco-GSP Greenville
10h 35m2 stops San Diego Nashville Intl
$357Southwest
Wed, Dec 9 - Wed, Dec 16
Southwest Logo
7:05 am - 12:50 pmGSP  Greenville-SFO San Francisco
8h 45m2 stops Nashville Intl San Diego
Southwest Logo
7:15 am - 8:50 pmSFO  San Francisco-GSP Greenville
10h 35m2 stops San Diego Nashville Intl
$362Southwest
Fri, Dec 11 - Mon, Dec 14
American Airlines Logo
5:17 pm - 10:31 pmGSP  Greenville-SFO San Francisco
8h 14m1 stop Dallas/Fort Worth
American Airlines Logo
6:38 am - 4:23 pmSFO  San Francisco-GSP Greenville
6h 45m1 stop Dallas/Fort Worth
$369American Airlines
Thu, Dec 3 - Sat, Dec 5
Delta Logo
5:40 am - 12:47 pmGSP  Greenville-SFO San Francisco
10h 07m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:59 pm - 11:13 amSFO  San Francisco-GSP Greenville
8h 14m1 stop Atlanta Hartsfield-Jackson
$369Delta
Sat, Dec 19 - Tue, Dec 29
United Airlines Logo
6:24 pm - 12:59 amGSP  Greenville-SFO San Francisco
9h 35m1 stop Chicago O'Hare Intl
United Airlines Logo
10:34 pm - 9:28 amSFO  San Francisco-GSP Greenville
7h 54m1 stop Chicago O'Hare Intl
$369United Airlines
Thu, Dec 3 - Wed, Dec 9
Alaska Airlines Logo
11:36 am - 9:20 pmGSP  Greenville-SFO San Francisco
12h 44m2 stops Chicago O'Hare Intl San Diego
Alaska Airlines Logo
7:00 am - 9:56 pmSFO  San Francisco-GSP Greenville
11h 56m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
$677Alaska Airlines
Thu, Dec 3 - Mon, Dec 7
Alaska Airlines Logo
11:36 am - 10:53 pmGSP  Greenville-SFO San Francisco
14h 17m2 stops Chicago O'Hare Intl San Diego
Alaska Airlines Logo
7:05 pm - 11:06 amSFO  San Francisco-GSP Greenville
13h 01m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl
$677Alaska Airlines
Booking Insights

Price, demand and travel trends for Greenville to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Greenville to San Francisco?

Round-trip flights from Greenville to San Francisco typically range from $432 to $676. The lowest price found in the past 5 days was $319, on Delta.

What's the cheapest day of the week to fly from Greenville to San Francisco?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Greenville to San Francisco. It’s 19% cheaper than the average day, while Sunday is the most expensive, with prices 48% higher.

What’s the cheapest month to fly from Greenville to San Francisco?

•July and September are the cheapest months to fly from Greenville to San Francisco at $466 round-trip.
•January ($685) and May ($577) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 46% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Key details for Greenville to San Francisco flights

Low season

November

Cheapest flight

$140
Beat the crowds with an average 25% drop in travelers.
The most popular month to fly with an average 46% increase in travelers.
One-way flight from Greenville to San Francisco

When to book flights from Greenville to San Francisco

Are your dates flexible? Find out the best times to travel from Greenville to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Greenville to San Francisco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Greenville to San Francisco?

    Three cabin classes are available on flights from Greenville to San Francisco:

    • Economy Class
    • Business Class
    • First Class

  • How long is a flight from Greenville to San Francisco?

    A nonstop flight from Greenville to San Francisco takes 00m, covering 2,227 miles.

  • Do I need a passport to fly from Greenville to San Francisco?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Greenville to San Francisco flight?

    Round-trip flights from Greenville to San Francisco range from $432 to $676, with an average of $526 over the past 12 months. Anything below $432 counts as a good deal.

  • How are flight prices from Greenville to San Francisco looking right now?

    One-way fares from Greenville to San Francisco are currently lower than usual. Average one-way flight prices are about $216, which is 13% below the typical average for this route.

  • What car rental options are available at San Francisco Airport (SFO)?

    San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include:

    • Europcar
    • Thrifty
    • Dollar
    • Hertz
    • Fox

  • Which airports can I use when flying from Greenville to San Francisco?

    Flights from Greenville to San Francisco usually depart from Greenville (GSP) and arrive at San Francisco (SFO).

  • Which airports do connecting flights from Greenville to San Francisco pass through?

    One-stop flights from Greenville to San Francisco most commonly connect through:

    • Atlanta Hartsfield-Jackson (ATL) - 43% of one-stop connections
    • Charlotte Douglas (CLT) - 27% of one-stop connections
    • Dallas/Fort Worth (DFW) - 17% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 6% of one-stop connections

  • Can I save money by using flexible dates for flights from Greenville to San Francisco?

    Yes. Flexible dates can save you up to 46% on flights from Greenville to San Francisco. Tuesday is the cheapest departure day at $430 round-trip on average, while Sunday is the most expensive at $783, a difference of $353.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Greenville to San Francisco?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 27m, compared with 7h 52m via Charlotte Douglas (CLT) and 8h via Washington, D.C. Dulles Intl (IAD).

  • What is the time difference between Greenville and San Francisco?

    San Francisco is 3 hours behind Greenville (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Francisco?

    Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Your guide to booking Greenville to San Francisco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Sunday. On this route, Tuesday flights average $430, about $353 less than Sunday fares (45% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Greenville to San Francisco trip for July. Fares historically average $466 round-trip in that month - typically $219 less than the most expensive month, which is January (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

    • Grand Hyatt At Sfo

More options for your flight from Greenville to San Francisco

Complete your trip to San Francisco with a hotel stay or car rental