GUA - SCL

$347 Find Cheap Flights from Guatemala City to Santiago - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guatemala City to Santiago departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guatemala City to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guatemala City to Santiago, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$631
Typical prices: $509-$632
Multiple Airlines
Thu 10/29Mon 11/9
GUA - SCL • 1 stop
Cheapest one-way
$347
Typical prices: $278-$321
Copa Airlines
Tue 9/1
GUA - SCL • 2 stops
Top airlines
Cheapest • from $676 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Guatemala City and Santiago. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $611 (round-trip)
Shortest trip • 10h 51m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 4% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 4% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guatemala City to Santiago (GUA-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guatemala City to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guatemala City to Santiago

Thu, Oct 29 - Mon, Nov 9
Multiple Airlines Logo
9:42 am - 1:13 am
GUA
-
SCL
12h 31m
1 stop
Multiple Airlines Logo
3:37 pm - 7:30 am
SCL
-
GUA
18h 53m
2 stops
$631Multiple Airlines
Tue, Aug 18 - Mon, Aug 24
Multiple Airlines Logo
6:24 am - 11:26 pm
GUA
-
SCL
15h 02m
2 stops
Multiple Airlines Logo
12:30 am - 1:00 pm
SCL
-
GUA
14h 30m
1 stop
$665Multiple Airlines
Wed, Jul 8 - Tue, Jul 21
Multiple Airlines Logo
4:28 pm - 5:14 am
GUA
-
SCL
10h 46m
1 stop
Multiple Airlines Logo
6:40 am - 5:00 pm
SCL
-
GUA
12h 20m
1 stop
$669Multiple Airlines
Mon, Aug 10 - Sun, Aug 30
Multiple Airlines Logo
10:34 am - 10:43 pm
GUA
-
SCL
10h 09m
1 stop
Multiple Airlines Logo
1:11 am - 7:30 am
SCL
-
GUA
32h 19m
1 stop
$670Multiple Airlines
Thu, Oct 22 - Mon, Nov 2
Multiple Airlines Logo
9:42 am - 5:17 am
GUA
-
SCL
40h 35m
2 stops
Multiple Airlines Logo
3:48 am - 11:50 am
SCL
-
GUA
11h 02m
1 stop
$671Multiple Airlines
Tue, Aug 18 - Mon, Aug 24
Multiple Airlines Logo
7:09 am - 3:00 am
GUA
-
SCL
17h 51m
1 stop
Multiple Airlines Logo
12:30 am - 1:00 pm
SCL
-
GUA
14h 30m
1 stop
$673Multiple Airlines
Sun, Jul 19 - Sun, Jul 26
Multiple Airlines Logo
4:23 am - 10:43 pm
GUA
-
SCL
16h 20m
1 stop
Multiple Airlines Logo
6:40 am - 5:00 pm
SCL
-
GUA
12h 20m
1 stop
$675Multiple Airlines
Fri, Aug 7 - Mon, Aug 10
Copa Airlines Logo
1:00 pm - 2:20 am
GUA
-
SCL
11h 20m
1 stop
Copa Airlines Logo
11:22 am - 9:37 pm
SCL
-
GUA
12h 15m
2 stops
$676Copa Airlines
Sun, Aug 23 - Fri, Aug 28
Avianca Logo
9:30 am - 4:45 am
GUA
-
SCL
17h 15m
1 stop
Avianca Logo
12:30 am - 1:00 pm
SCL
-
GUA
14h 30m
1 stop
$677Avianca
Wed, Jul 8 - Mon, Jul 20
Copa Airlines Logo
6:24 am - 10:43 pm
GUA
-
SCL
14h 19m
2 stops
Copa Airlines Logo
2:56 am - 11:47 am
SCL
-
GUA
10h 51m
1 stop
$678Copa Airlines
Booking Insights

KAYAK's insights & trends for Guatemala City to Santiago flights

Get data-powered insights and trends into flights from Guatemala City to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Guatemala City to Santiago?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Guatemala City to Santiago departing in October.

What is the cheapest month to fly from Guatemala City to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Guatemala City to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Guatemala City to Santiago is November, where tickets cost $550 (return) on average. On the other hand, the most expensive months are July and October, where the average cost of round-trip tickets is $614 and $601 respectively.

How far in advance should I book a flight from Guatemala City to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Guatemala City to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Guatemala City to Santiago, you should book around 3 weeks before departure, which saves you about 4% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 16 weeks before departure.

Good to know

Low seasonMay
Cheapest flight$347
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Guatemala City to Santiago

When to book flights from Guatemala City to Santiago

Are your dates flexible? Find out the best times to travel from Guatemala City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guatemala City to Santiago

  • What is the cheapest flight from Guatemala City to Santiago?

    In the last 5 days, the lowest price for a flight from Guatemala City to Santiago was $347 for a one-way ticket and $665 for a round-trip.

  • Do I need a passport to fly between Guatemala City and Santiago?

    Yes

  • Which aircraft models fly most regularly from Guatemala City to Santiago?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Guatemala City to Santiago?

    Star Alliance is the only airline alliance operating flights between Guatemala City and Santiago.

  • Which is the best airline for flights from Guatemala City to Santiago, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Guatemala City to Santiago are Copa Airlines and Avianca. With an average price for the route of $582 and an overall rating of 7.6, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $603 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Guatemala City to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guatemala City to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guatemala City to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Guatemala City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guatemala City to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Guatemala City with another airline. Booking your flights between Guatemala City and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guatemala City to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Guatemala City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Guatemala City to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Guatemala City to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guatemala City to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1568 reviews
7.8Boarding
6.9Food
7.4Comfort
8.1Crew
6.8Entertainment
Airline reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

2.0 MediocreFred, May 2026
UIO - PTY
Read more Copa Airlines reviews

I had to run from the end of terminal one to the end of terminal two to make the connecting flight....probably a kilometer. No electric carts were available. I'm 76 and literally had to run to make the connection at the last minute. The connecting time was absolutely unrealistic. When Last Call was announced, I tried to get other Copa gate staff to call Gate 221 to let them know I was on my way, but they said no. I came within 1 minute of missing the flight.

I was flying business class, and the French fellow passengers were super noisy. It was not a comfortable flight. And the crew was not helpful.

Boarding was a mess, they call all priority members without distinction so gold, platinum, silver were all mixed together in a long line which defeats the purpose

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

The food is terrible I ask for water never got transport my mother we’re late and my sister from Lima was the worst waiting to long for wheelchair

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

The employees at the gate were not communicating, they preferred to give the upgrade to pilots and not to the elite passengers Every flight I more disappointing, clients shooed be priority instead of other employees even if they are pilots, there was plenty room for pilots in economy

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

They should provide water to passengers who ask for it

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Everything you need to know for your flight from Guatemala City to Santiago

Information on your arrival and departure airports