GUA - SCL

$456 Find Cheap Flights from Guatemala City to Santiago - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$586
Typical prices: $564-$695
Multiple Airlines
Fri 3/9Thu 3/22
GUA - SCL • 1 stop
Cheapest one-way
$312
Typical prices: $290-$388
Multiple Airlines
Sun 4/8
GUA - SCL • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Guatemala City and Santiago. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 13% compared to booking last minute.
Insights
Insights
When to travel
April
Cheapest • 10% price drop
November
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Medellín Jose Maria Cordova Intl (MDE)
Cheapest • Avg $582 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 11h (one-way)
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Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guatemala City to Santiago (GUA-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guatemala City to Santiago

Tue, Mar 9 - Mon, Mar 22
Multiple Airlines Logo
1:47 pm - 1:13 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
32h 26m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
2:13 am - 12:57 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
13h 44m1 stop Medellín Jose Maria Cordova Intl
$586Multiple Airlines
Wed, Mar 10 - Mon, Mar 15
Avianca Logo
9:20 am - 1:05 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
12h 45m1 stop Bogotá El Dorado
Avianca Logo
2:10 am - 1:05 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
13h 55m1 stop Bogotá El Dorado
$598Avianca
Wed, Apr 21 - Wed, Apr 28
Avianca Logo
1:55 pm - 4:45 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
12h 50m1 stop Bogotá El Dorado
Avianca Logo
3:20 pm - 1:40 amSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
12h 20m1 stop Bogotá El Dorado
$598Avianca
Wed, Mar 10 - Tue, Mar 16
Avianca Logo
9:20 am - 1:05 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
12h 45m1 stop Bogotá El Dorado
Avianca Logo
7:30 am - 5:25 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
12h 55m1 stop Bogotá El Dorado
$598Avianca
Thu, Apr 1 - Wed, Apr 14
Copa Airlines Logo
5:50 am - 12:04 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
15h 14m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
2:52 am - 9:11 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
20h 19m2 stops Panama City Tocumen Intl San José Juan Santamaria Intl
$621Copa Airlines
Wed, Nov 25 - Thu, Dec 3
Copa Airlines Logo
6:19 am - 12:24 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
15h 05m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
5:07 am - 11:53 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
21h 46m1 stop Panama City Tocumen Intl
$621Copa Airlines
Wed, Apr 14 - Wed, Apr 21
Copa Airlines Logo
5:50 am - 2:41 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
18h 51m2 stops San José Juan Santamaria Intl Panama City Tocumen Intl
Copa Airlines Logo
11:30 am - 7:35 amSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
22h 05m1 stop Panama City Tocumen Intl
$621Copa Airlines
Tue, Dec 22 - Mon, Jan 11
Multiple Airlines Logo
8:37 am - 1:13 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
13h 36m1 stop Medellín Jose Maria Cordova Intl
Multiple Airlines Logo
6:07 am - 8:49 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
41h 42m2 stops Lima J Chavez Intl Mexico City Benito Juarez
$821Multiple Airlines
Sun, Nov 22 - Sun, Nov 29
Multiple Airlines Logo
7:00 am - 9:18 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
23h 18m3 stops San José Juan Santamaria Intl Lima J Chavez Intl Antofagasta Cerro Moreno
Multiple Airlines Logo
7:30 am - 1:05 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
32h 35m1 stop Bogotá El Dorado
$863Multiple Airlines
Mon, Nov 23 - Tue, Dec 1
Multiple Airlines Logo
9:45 pm - 1:05 amGUA  Guatemala City La Aurora-SCL Santiago Arturo Merino Benitez
24h 20m2 stops San José Juan Santamaria Intl Bogotá El Dorado
Multiple Airlines Logo
8:35 pm - 8:49 pmSCL  Santiago Arturo Merino Benitez-GUA Guatemala City La Aurora
27h 14m2 stops Lima J Chavez Intl Mexico City Benito Juarez
$876Multiple Airlines
Booking Insights

Price, demand and travel trends for Guatemala City to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from Guatemala City to Santiago?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Guatemala City to Santiago. It’s 3% cheaper than the average day, while Wednesday is the most expensive, with prices 6% higher.

What’s the cheapest month to fly from Guatemala City to Santiago?

•April is the cheapest month to fly from Guatemala City to Santiago at $558 round-trip.
•October ($674) and December ($673) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 20% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Guatemala City to Santiago the cheapest?

Flights from Guatemala City to Santiago are cheapest 7 weeks before departure. Booking in this window typically costs about 13% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Guatemala City to Santiago flights

Low season

June

Cheapest flight

$312
Beat the crowds with an average 47% drop in travelers.
The most popular month to fly with an average 95% increase in travelers.
One-way flight from Guatemala City to Santiago

When to book flights from Guatemala City to Santiago

Are your dates flexible? Find out the best times to travel from Guatemala City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Guatemala City to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Guatemala City to Santiago?

    Only Economy Class is available on flights from Guatemala City to Santiago.

  • How long is a flight from Guatemala City to Santiago?

    A nonstop flight from Guatemala City to Santiago takes 00m, covering 3,559 miles.

  • Do I need a passport to fly from Guatemala City to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Guatemala City to Santiago flight?

    Round-trip flights from Guatemala City to Santiago range from $564 to $695, with an average of $619 over the past 12 months. Anything below $564 counts as a good deal.

  • How expensive are last-minute Guatemala City to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 6% above the $619 route average. Book 7 weeks before departure for the lowest fares.

  • Have flight prices from Guatemala City to Santiago changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $586 to $1,808. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Guatemala City to Santiago looking right now?

    One-way fares from Guatemala City to Santiago are currently higher than usual. Average one-way flight prices are about $492, which is 42% above the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Guatemala City to Santiago?

    Flights from Guatemala City to Santiago usually depart from Guatemala City La Aurora (GUA) and arrive at Santiago Arturo Merino Benitez (SCL).

  • Which airports do connecting flights from Guatemala City to Santiago pass through?

    One-stop flights from Guatemala City to Santiago most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 52% of one-stop connections
    • Bogotá El Dorado (BOG) - 47% of one-stop connections
    • Medellín Jose Maria Cordova Intl (MDE) - 0% of one-stop connections

  • Can I save money by using flexible dates for flights from Guatemala City to Santiago?

    Yes. Flexible dates can save you up to 9% on flights from Guatemala City to Santiago. Tuesday is the cheapest departure day at $602 round-trip on average, while Wednesday is the most expensive at $661, a difference of $59.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Guatemala City to Santiago?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 11h, compared with 12h 45m via Bogotá El Dorado (BOG) and 22h 48m via Medellín Jose Maria Cordova Intl (MDE).

  • What is the time difference between Guatemala City and Santiago?

    Santiago is 3 hours ahead of Guatemala City (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

Your guide to booking Guatemala City to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Wednesday. On this route, Tuesday flights average $602, about $59 less than Wednesday fares (9% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 7 weeks before you fly. On this route, that window historically saves about 13% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Guatemala City to Santiago trip for April. Fares historically average $558 round-trip in that month - typically $116 less than the most expensive month, which is October (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

More options for your flight from Guatemala City to Santiago

Complete your trip to Santiago with a hotel stay or car rental

Car rentals in Santiago
Hotels in Santiago
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