GYE - TYS

$850 Find Cheap Flights from Guayaquil to Knoxville - Compare and Save

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guayaquil to Knoxville departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$850
United Airlines
Tue 9/1Tue 9/8
GYE - TYS • 2 stops
Top airlines
Cheapest • from $808 (round-trip)
Best reviews • 7.8 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Guayaquil and Knoxville. You'll need at least 1 connection.
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Flight Deals

Cheap Flights from Guayaquil to Knoxville (GYE-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guayaquil to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Knoxville

Tue, Sep 1 - Tue, Sep 8
United Airlines Logo
12:22 pm - 9:45 pm
GYE
-
TYS
32h 23m
2 stops
United Airlines Logo
7:15 am - 8:52 pm
TYS
-
GYE
14h 37m
2 stops
$850United Airlines
Tue, Aug 11 - Thu, Aug 27
American Airlines Logo
6:00 am - 11:51 pm
GYE
-
TYS
16h 51m
1 stop
American Airlines Logo
6:06 am - 9:39 pm
TYS
-
GYE
16h 33m
1 stop
$873American Airlines
Tue, Aug 11 - Thu, Aug 27
American Airlines Logo
6:00 am - 11:51 pm
GYE
-
TYS
16h 51m
1 stop
American Airlines Logo
7:04 am - 9:39 pm
TYS
-
GYE
15h 35m
2 stops
$878American Airlines
Tue, Aug 11 - Thu, Aug 27
United Airlines Logo
8:28 am - 9:45 pm
GYE
-
TYS
36h 17m
2 stops
United Airlines Logo
7:15 am - 8:53 pm
TYS
-
GYE
14h 38m
2 stops
$880United Airlines
Tue, Sep 1 - Tue, Sep 8
Copa Airlines Logo
12:22 pm - 6:17 pm
GYE
-
TYS
28h 55m
2 stops
Copa Airlines Logo
7:15 am - 5:30 pm
TYS
-
GYE
11h 15m
2 stops
$890Copa Airlines
Tue, Sep 1 - Tue, Sep 8
Copa Airlines Logo
8:28 am - 6:17 pm
GYE
-
TYS
32h 49m
2 stops
Copa Airlines Logo
7:15 am - 11:37 pm
TYS
-
GYE
17h 22m
2 stops
$895Copa Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:00 am - 11:51 pm
GYE
-
TYS
16h 51m
1 stop
American Airlines Logo
6:06 am - 9:39 pm
TYS
-
GYE
16h 33m
1 stop
$919American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:00 am - 11:51 pm
GYE
-
TYS
16h 51m
1 stop
American Airlines Logo
6:06 am - 9:39 pm
TYS
-
GYE
16h 33m
1 stop
$920American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:00 am - 11:51 pm
GYE
-
TYS
16h 51m
1 stop
American Airlines Logo
6:00 am - 9:39 pm
TYS
-
GYE
16h 39m
1 stop
$921American Airlines
Tue, Sep 1 - Tue, Sep 8
American Airlines Logo
6:00 am - 11:51 pm
GYE
-
TYS
16h 51m
1 stop
American Airlines Logo
6:06 am - 9:39 pm
TYS
-
GYE
16h 33m
1 stop
$922American Airlines
Booking Insights

KAYAK's insights & trends for Guayaquil to Knoxville flights

Get data-powered insights and trends into flights from Guayaquil to Knoxville to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Guayaquil to Knoxville?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from Guayaquil to Knoxville were found on American Airlines ($808) and United Airlines ($850).

Good to know

Cheapest flight$850
Flight from Guayaquil to Knoxville

When to book flights from Guayaquil to Knoxville

Are your dates flexible? Find out the best times to travel from Guayaquil to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guayaquil to Knoxville

  • What is the cheapest flight from Guayaquil to Knoxville?

    In the last 5 days, the lowest price for a flight from Guayaquil to Knoxville was $808 for a round-trip ticket.

  • Do I need a passport to fly between Guayaquil and Knoxville?

    Yes, you’ll need a passport to travel to Knoxville from Guayaquil.

  • Which aircraft models fly most regularly from Guayaquil to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Guayaquil to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Guayaquil and Knoxville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Guayaquil to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Guayaquil to Knoxville are Delta and American Airlines. With an average price for the route of $793 and an overall rating of 7.8, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $835 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Guayaquil to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guayaquil to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guayaquil to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Guayaquil is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guayaquil to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Guayaquil with another airline. Booking your flights between Guayaquil and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guayaquil to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Guayaquil up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Guayaquil to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Guayaquil to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guayaquil to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8452 reviews
7.8Comfort
8.5Crew
8.1Boarding
7.8Entertainment
7.2Food
Airline reviews

The flights are constantly late anymore, and they won't even give you a glass of water on the plane. For years, they were able to do a service on this flight from Atlanta to Knoxville and Knoxville Atlanta now they say it's too short of a flight. You can't even get a quick drink of water.

4.0 OkayKelli, Jun 2026
ATL - TYS
Read more Delta reviews

The flights are constantly late anymore, and they won't even give you a glass of water on the plane. For years, they were able to do a service on this flight from Atlanta to Knoxville and Knoxville Atlanta now they say it's too short of a flight. You can't even get a quick drink of water.

Should never have had to go to Detroit from Orlando back to Tennessee!

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Same experience as the flight from Norfolk to Atlanta where people are boarded in zones that don't make sense. People behind you on the plane will get on before you and they take the luggage space on your row.

Smallest leg room I've ever had on a plane.

We departed late, and we arrived to Atlanta late for our connecting flight to Quito. I asked the flight attendant before landing to please make an announcement and let us go out of the plane first she agreed but never did the announcement. We run and arrived 3 minutes late and they closed the gate of the plane. We ended up staying one day in Atlanta for the next flight to Quito. When we arrived to Quito 2 of our 50lbs bags arrived completely broken and destroyed. I made the complaint and so far nobody in Delta wants to help.

The plant way delayed departing by 3 hours. It was an old airplane with broken seats and armrests. The bathroom made a hollering sound. A really crappy flight experience and travel day all around.

Kind staff. Snacks are small but that’s the new normal.

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

Flight was great. DELTA did a fantastic job! ATL was busy, as usual!

Delayed by 5 hours and I had to wit in the airport for more than 6+ hours.

technology worked well and everything ran smoothly. The seats are quite cramped so please don't try to re-engineer the cabin to squeeze more bodies on board.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Arrived early picked up my bag in a few minutes- great trip - thank you

Flight was smooth, quick and felt safe. The 2 delays not happening would have been better but I guess that happens in the airline industry

The pilot greased the landing and the crew was fantastic.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

At least it was a short flight. Greyhound with wings.

Our flight got changed and/or delayed 8 times before we boarded.

Everything you need to know for your flight from Guayaquil to Knoxville

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