GYE - TYS

$245 Find Cheap Flights from Guayaquil to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guayaquil to Knoxville departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$474
Multiple Airlines
Wed 2/11Tue 5/19
GYE - TYS • 1 stop
Cheapest one-way
$245
Multiple Airlines
Wed 2/11
GYE - TYS • 1 stop
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We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guayaquil to Knoxville (GYE-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guayaquil to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Knoxville

Wed, Feb 11 - Tue, May 19
Multiple Airlines Logo
12:59 am - 8:42 pm
GYE
-
TYS
19h 43m1 stop
Multiple Airlines Logo
3:48 pm - 10:40 pm
TYS
-
GYE
31h 52m2 stops
$474Multiple Airlines
Thu, Feb 19 - Thu, May 7
Multiple Airlines Logo
12:59 am - 12:41 pm
GYE
-
TYS
11h 42m1 stop
Multiple Airlines Logo
11:27 am - 5:20 pm
TYS
-
GYE
30h 53m2 stops
$481Multiple Airlines
Wed, Feb 18 - Thu, Feb 26
Multiple Airlines Logo
12:59 am - 8:42 pm
GYE
-
TYS
19h 43m1 stop
Multiple Airlines Logo
3:25 pm - 12:04 am
TYS
-
GYE
8h 39m1 stop
$501Multiple Airlines
Wed, Feb 18 - Thu, Feb 26
Multiple Airlines Logo
4:40 am - 10:10 pm
GYE
-
TYS
17h 30m2 stops
Multiple Airlines Logo
3:25 pm - 12:04 am
TYS
-
GYE
8h 39m1 stop
$512Multiple Airlines
Wed, Feb 18 - Thu, Feb 26
Multiple Airlines Logo
12:59 am - 12:00 pm
GYE
-
TYS
35h 01m3 stops
Multiple Airlines Logo
3:25 pm - 12:04 am
TYS
-
GYE
8h 39m1 stop
$529Multiple Airlines
Wed, Feb 18 - Sun, May 10
Multiple Airlines Logo
12:59 am - 8:42 pm
GYE
-
TYS
19h 43m1 stop
Multiple Airlines Logo
11:27 am - 10:40 pm
TYS
-
GYE
12h 13m2 stops
$536Multiple Airlines
Wed, Feb 11 - Sat, May 16
Multiple Airlines Logo
12:59 am - 8:42 pm
GYE
-
TYS
19h 43m1 stop
Multiple Airlines Logo
9:00 am - 10:40 pm
TYS
-
GYE
14h 40m2 stops
$551Multiple Airlines
Wed, Feb 11 - Sat, May 16
Multiple Airlines Logo
12:59 am - 8:42 pm
GYE
-
TYS
19h 43m1 stop
Multiple Airlines Logo
11:56 am - 11:01 pm
TYS
-
GYE
12h 05m1 stop
$575Multiple Airlines
Sun, Mar 1 - Sat, May 2
Multiple Airlines Logo
12:59 am - 8:46 pm
GYE
-
TYS
19h 47m1 stop
Multiple Airlines Logo
11:56 am - 11:01 pm
TYS
-
GYE
12h 05m1 stop
$582Multiple Airlines
Wed, Feb 18 - Sun, May 10
Multiple Airlines Logo
12:59 am - 8:42 pm
GYE
-
TYS
19h 43m1 stop
Multiple Airlines Logo
9:40 pm - 11:01 pm
TYS
-
GYE
26h 21m1 stop
$584Multiple Airlines
Booking Insights

KAYAK's insights & trends for Guayaquil to Knoxville flights

Get data-powered insights and trends into flights from Guayaquil to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Guayaquil to Knoxville?

The average price of all round-trip flights from Guayaquil to Knoxville clicked on KAYAK for each day over the last 12 months.

When flying from Guayaquil to Knoxville, you should consider leaving on a Monday and avoid Wednesdays if you are looking for the best rates. For your return to Guayaquil, you’ll find the best rates on Wednesdays and the most expensive ones on Saturdays.

Good to know

Cheapest flight$245
Flight from Guayaquil to Knoxville

When to book flights from Guayaquil to Knoxville

Are your dates flexible? Find out the best times to travel from Guayaquil to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guayaquil to Knoxville

  • What is the cheapest flight from Guayaquil to Knoxville?

    In the last 3 days, the lowest price for a flight from Guayaquil to Knoxville was $245 for a one-way ticket and $474 for a round-trip.

  • Do I need a passport to fly between Guayaquil and Knoxville?

    Yes, you’ll need a passport to travel to Knoxville from Guayaquil.

  • Which aircraft models fly most regularly from Guayaquil to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Guayaquil to Knoxville?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Guayaquil and Knoxville, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Guayaquil to Knoxville, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Guayaquil to Knoxville are Delta and United Airlines. With an average price for the route of $793 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $636 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Guayaquil to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guayaquil to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guayaquil to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Guayaquil is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guayaquil to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Guayaquil with another airline. Booking your flights between Guayaquil and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guayaquil to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Guayaquil up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Guayaquil to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Guayaquil to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guayaquil to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8014 reviews
7.9Comfort
7.9Entertainment
7.3Food
8.5Crew
8.1Boarding
Airline reviews

Premium economy is like the forgotten class. Aside from meal service never saw a flight attendant. Any additional beverages required going to the very back of the plane to request and there was rarely an attendant there. Seat leg / foot rest hardly elevates and not well suite for someone under 5’6. Bulky armrests

4.0 OkayWanda, Dec 2025
FCO - JFK
Read more Delta reviews

Premium economy is like the forgotten class. Aside from meal service never saw a flight attendant. Any additional beverages required going to the very back of the plane to request and there was rarely an attendant there. Seat leg / foot rest hardly elevates and not well suite for someone under 5’6. Bulky armrests

Flight delays both to Detroits and return flight . The flight to Detroit was associated with mechanical difficulty

Flight was operated by Virgin Atlantic and it was up to their usual high standard. Minor grips about some issues, but they are really first world issues and as a whole, was an excellent flight.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

Delta One upgrade it would have been great if my tray extended (it was jammed and wouldn’t pull out), seatbelt had too much slack & my little cabin door didn’t close properly

I paid for a business class ticket on Delta. It was sourced to Virgin Atlantic. They changed out the aircraft which had fewer upper class tickets. Even though I'd checked into the lounge, was receiving alerts via kayak about the delay and changes; no one informed me that the seat would be changed - until I attempted to board and was told that I would have an economy seat or they could search to put me on another airline. Even the flight crew were informed of this change (10 passengers were bumped out of Upper Class) around 2 pm (1400) time. Hours would have helped to consider alternatives instead of making a last minute change. There needs to be compensation from both Delta and Virgin given this change in service/experience.

Wasn't a Delta issue I don't think, but seems there was a Delta flight at each of the 2 Dallas airports at the same exact time, both to Atlanta. I was evidently booked on the one at Love Airport, but the Carey transport shuttle took me to DFW instead and I ended up missing the flight by just a few minutes. Was able to book a Southwest flight from Love Airport, but was a big loss of time and an inconvenience.

Every single flight that we got on was delayed by several hours or more. I honestly didn’t think we would get out of Atlanta because our flight was supposed to leave at 7:59 and it kept getting kicked back further and further. Delta stands for Don’t Ever Leave The Airport!

Great. I had to modify a flight. That was easy and free. Thank You

I noticed that the planes seem to be outdated. There was no entertainment per se. Also, the waiting area did not have any working electrical outlets

The flight was delayed for 1:30 hours for maintenance issues. They should give more information about connecting flights. For a Business Cabin the Crew was mediocre.

Very turbulent trip made it pretty bearable, plus the lack of refreshments served and the lack of any air conditioning before takeoff which took an hour or more.

Flight was late - I was downgraded from first class to coach

Not good - outbound flight was delayed and missed my connection even though I got to the gate after running through the airport - the agent would not let me on because the door was closed (flight had not left). There was no notification from United - overall experience was very disappointing. Additionally, I was downgraded from first class to coach on the alternative flight

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

Movie selection is good. Crew did not understand mileage program and were no help. Sick later. Food?

Staff on board was excellent. Positive upbeat helpful- like it used to be.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

For an expensive flight to another country, United has a lot of nerve serving pretzels and no meals (unless, of course, you want to buy something to eat). Unacceptable.

The food is terrible. The same pasta or chicken with bad taste and presentation

Everything you need to know for your flight from Guayaquil to Knoxville

Information on your arrival and departure airports