GYE - TYS

$250 Find Cheap Flights from Guayaquil to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guayaquil to Knoxville departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Knoxville, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Guayaquil to Knoxville (GYE-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guayaquil to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Knoxville

Mon, Sep 15 - Wed, Oct 29
United Airlines Logo
8:32 am - 6:10 pmGYE-TYS
32h 38m2 stops
United Airlines Logo
9:10 am - 1:32 pmTYS-GYE
29h 22m2 stops
$596United Airlines
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Sun, Nov 2 - Mon, Dec 8
Logo
3:30 am - 8:09 pmGYE-TYS
16h 39m2 stops
Logo
11:42 am - 11:25 amTYS-GYE
23h 43m2 stops
$622
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Mon, Nov 3 - Mon, Dec 8
Logo
2:35 pm - 11:44 pmGYE-TYS
33h 09m2 stops
Logo
11:42 am - 11:25 amTYS-GYE
23h 43m2 stops
$623
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Fri, Sep 19 - Thu, Oct 23
United Airlines Logo
12:17 pm - 6:10 pmGYE-TYS
28h 53m2 stops
United Airlines Logo
7:15 am - 11:37 pmTYS-GYE
17h 22m2 stops
$626United Airlines
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Mon, Oct 20 - Mon, Nov 10
American Airlines Logo
8:15 am - 11:29 amGYE-TYS
26h 14m2 stops
American Airlines Logo
7:20 pm - 10:40 pmTYS-GYE
27h 20m2 stops
$705American Airlines
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Mon, Oct 20 - Mon, Nov 10
American Airlines Logo
8:15 am - 9:52 amGYE-TYS
24h 37m2 stops
American Airlines Logo
7:20 pm - 10:40 pmTYS-GYE
27h 20m2 stops
$706American Airlines
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Mon, Nov 3 - Tue, Dec 9
Delta Logo
8:40 pm - 11:22 pmGYE-TYS
26h 42m2 stops
Delta Logo
4:00 pm - 2:05 amTYS-GYE
34h 05m2 stops
$743Delta
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Mon, Nov 3 - Sat, Dec 6
Delta Logo
8:40 pm - 11:22 pmGYE-TYS
26h 42m2 stops
Delta Logo
4:00 pm - 7:20 amTYS-GYE
15h 20m2 stops
$785Delta
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Fri, Sep 12 - Tue, Oct 28
Avianca Logo
3:15 am - 10:28 amGYE-TYS
30h 13m2 stops
Avianca Logo
5:45 am - 2:15 amTYS-GYE
21h 30m2 stops
$793Avianca
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Mon, Sep 15 - Thu, Oct 30
Avianca Logo
2:50 pm - 10:28 amGYE-TYS
42h 38m2 stops
Avianca Logo
5:45 am - 2:15 amTYS-GYE
21h 30m2 stops
$830Avianca
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Booking Insights

KAYAK's insights & trends for Guayaquil to Knoxville flights

Get data-powered insights and trends into flights from Guayaquil to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Guayaquil to Knoxville?

The average price of all round-trip flights from Guayaquil to Knoxville clicked on KAYAK for each day over the last 12 months.

When flying from Guayaquil to Knoxville, you should consider leaving on a Monday and avoid Wednesdays if you are looking for the best rates. For your return to Guayaquil, you’ll find the best rates on Wednesdays and the most expensive ones on Saturdays.

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Good to know

Cheapest flight$250
Flight from Guayaquil to Knoxville

When to book flights from Guayaquil to Knoxville

Are your dates flexible? Find out the best times to travel from Guayaquil to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guayaquil to Knoxville

  • What is the cheapest flight from Guayaquil to Knoxville?

    In the last 3 days, the lowest price for a flight from Guayaquil to Knoxville was $250 for a one-way ticket and $596 for a round-trip.

  • Do I need a passport to fly between Guayaquil and Knoxville?

    Yes, you’ll need a passport to travel to Knoxville from Guayaquil.

  • Which aircraft models fly most regularly from Guayaquil to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Guayaquil to Knoxville?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Guayaquil and Knoxville, with Star Alliance being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Guayaquil to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guayaquil to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guayaquil to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Guayaquil is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guayaquil to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Guayaquil with another airline. Booking your flights between Guayaquil and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guayaquil to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Guayaquil up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Guayaquil to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Guayaquil to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guayaquil to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8930 reviews
6.6Food
7.7Boarding
7.3Comfort
7.1Entertainment
8.1Crew
Airline reviews

I understand stuff happens, but plane failures are likely due to lack of maintenance. Additionally, air conditioning wasn't working, no snack/drink service, no WiFi. Fortunately, the crew was communicative and light-hearted. United grabbed another plane and we were able to get to our destination.

6.0 GoodMarydoug, Aug 2025SJC - DEN
Read more United Airlines reviews

I understand stuff happens, but plane failures are likely due to lack of maintenance. Additionally, air conditioning wasn't working, no snack/drink service, no WiFi. Fortunately, the crew was communicative and light-hearted. United grabbed another plane and we were able to get to our destination.

There was no food available for this red eye... one little waffle cookie for a 6+ hour flight... thank God I was able to sleep some

It is clear that someone knew, and competent, is in charge of food at United Airlines at least for the international flights. I was flying in coach, but the choices of the dinner were excellent. Tasty, and appropriate size. I had the beef, which was a little bit like a shepherds pie, and it was good. Nothing comparable has been served on a United flight in years. It will not be confused with three star food, but it is very good for airline food. Even better was the breakfast choice between a cinnamon roll and a breakfast sandwich. I chose the breakfast sandwich which was absolutely delicious and which I would happily order again at my local Starbucks or Panera. It is clear that someone knew indifferent is in charge of the food and it’s about time.

The flight was comfortable with the exit row and great service

Had to cancel first flight because Airporter Bus took over 3 hrs to get to airport which resulted in an extra $378 dollar fare . Is there anyway I can be reimbursed for initial fare since it was not my fault? Sent from my iPhone EJ Ledet

For both flights I requested a gluten free meal, they didn’t have one nor were there other options.

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Flight attendant in first class gave poor service (like he didn't want to be there) and food was awful. We sat waiting for gate upon arrival over 45 mins.

The experience was great, the crew was very polite and hospitable. I will definitely make if my go to airlines.

Inoperable monitor left no entert for 9 hours. Crew was not helpful Food was awful.

Everything you need to know for your flight from Guayaquil to Knoxville

Information on your arrival and departure airports

Guayaquil (GYE)
Knoxville (TYS)

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