GYE - TYS

$865 Find Cheap Flights from Guayaquil to Knoxville

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Guayaquil to Knoxville departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Guayaquil to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$865
American Airlines
Wed 5/27Wed 7/8
GYE - TYS • 1 stop
Top airlines
Cheapest • from $865 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Guayaquil and Knoxville. You'll need at least 1 connection.
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We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guayaquil to Knoxville (GYE-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Guayaquil to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Knoxville

Wed, May 27 - Wed, Jul 8
American Airlines Logo
2:31 pm - 11:59 pm
GYE
-
TYS
8h 28m
1 stop
American Airlines Logo
6:00 am - 1:25 pm
TYS
-
GYE
8h 25m
1 stop
$865American Airlines
Wed, May 27 - Wed, Jul 8
American Airlines Logo
6:00 am - 9:31 pm
GYE
-
TYS
14h 31m
2 stops
American Airlines Logo
7:17 pm - 1:25 pm
TYS
-
GYE
19h 08m
2 stops
$869American Airlines
Sun, May 17 - Fri, May 29
Multiple Airlines Logo
6:00 am - 6:15 pm
GYE
-
TYS
35h 15m
2 stops
Multiple Airlines Logo
7:10 am - 7:14 am
TYS
-
GYE
25h 04m
1 stop
$931Multiple Airlines
Tue, May 26 - Thu, May 28
United Airlines Logo
2:43 pm - 11:12 pm
GYE
-
TYS
31h 29m
2 stops
United Airlines Logo
7:15 am - 11:36 pm
TYS
-
GYE
17h 21m
2 stops
$1,021United Airlines
Sat, May 16 - Fri, May 29
Multiple Airlines Logo
8:28 am - 12:24 pm
GYE
-
TYS
26h 56m
2 stops
Multiple Airlines Logo
7:10 am - 7:14 am
TYS
-
GYE
25h 04m
1 stop
$1,073Multiple Airlines
Tue, May 26 - Thu, May 28
United Airlines Logo
2:43 pm - 11:54 pm
GYE
-
TYS
32h 11m
2 stops
United Airlines Logo
7:15 am - 5:29 pm
TYS
-
GYE
11h 14m
2 stops
$1,167United Airlines
Tue, May 26 - Thu, May 28
United Airlines Logo
8:28 am - 11:54 pm
GYE
-
TYS
38h 26m
2 stops
United Airlines Logo
7:15 am - 5:29 pm
TYS
-
GYE
35h 14m
2 stops
$1,231United Airlines
Sat, May 16 - Fri, May 29
United Airlines Logo
12:22 pm - 4:54 pm
GYE
-
TYS
27h 32m
2 stops
United Airlines Logo
5:45 am - 5:29 pm
TYS
-
GYE
12h 44m
2 stops
$1,339United Airlines
Sat, May 16 - Fri, May 29
American Airlines Logo
6:05 am - 11:59 pm
GYE
-
TYS
16h 54m
1 stop
American Airlines Logo
6:00 am - 1:31 pm
TYS
-
GYE
8h 31m
1 stop
$1,380American Airlines
Booking Insights

KAYAK's insights & trends for Guayaquil to Knoxville flights

Get data-powered insights and trends into flights from Guayaquil to Knoxville to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Guayaquil to Knoxville?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Guayaquil to Knoxville were found on American Airlines ($865) and United Airlines ($1,021).

Good to know

Cheapest flight$865
Flight from Guayaquil to Knoxville

When to book flights from Guayaquil to Knoxville

Are your dates flexible? Find out the best times to travel from Guayaquil to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Guayaquil to Knoxville

  • What is the cheapest flight from Guayaquil to Knoxville?

    In the last 3 days, the lowest price for a flight from Guayaquil to Knoxville was $865 for a round-trip ticket.

  • Do I need a passport to fly between Guayaquil and Knoxville?

    Yes, you’ll need a passport to travel to Knoxville from Guayaquil.

  • Which aircraft models fly most regularly from Guayaquil to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Guayaquil to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Guayaquil and Knoxville, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Guayaquil to Knoxville, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Guayaquil to Knoxville are Delta and American Airlines. With an average price for the route of $793 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $835 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Guayaquil to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Guayaquil to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Guayaquil to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Guayaquil is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Guayaquil to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Guayaquil with another airline. Booking your flights between Guayaquil and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Guayaquil to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Guayaquil up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Guayaquil to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Guayaquil to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Guayaquil to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8459 reviews
8.5Crew
7.2Food
7.9Comfort
7.8Entertainment
8.1Boarding
Airline reviews

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

10.0 ExcellentIrmara, May 2026
MCO - BOS
Read more Delta reviews

Much better than Latam, the worse airline company ever. I hope I don't have the need to fly Latam ever in my life again.

Everything could and should be better. We are paying for, it's not a favor, it's a service and should involve quality, responsibility and respect.

Seats were comfortable, 8 hours. One flight attendant was not appropriate in his verbal response: "Please, DON'T touch me.", after being tapped near his elbow after being made unaware he skipped serving me & had passed further down the aisle.

Boarding in Amsterdam is always chaotic. More complicated than needs to be ( boarding pass checked twice, once for general security, then by the airline). The bathrooms on this flight are dirty, and smelly. The food was mediocre at best The crew was decent

Seats in Delta Main are unbelievably close to the seat in front of. Hard to get a backpack under the seat.

Round trip flight to Canada and back to the US was smooth and efficient.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

Spanish speaker flight attendants were incredibly rude. A male flight attendant named Allen, grabbed my bag out of the overhead bin and moved it without my permission. When I asked what he was doing, he informed me that the overhead bins were public space? It would be easy to ignore this comment, as you don’t know the whole story, but the flight attendants were militant and rude. Delta, you can do better!

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Everything was fine except the end of the flight. We spent more than an hour circling around Miami due to weather conditions. That was not good.

They lost my bag. ... And I asked them 3 times to 3 different people if my checked bag will maKe it all the way - they all confirmed and at the end it was left at the connection... Bravo

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Delayed due to weather in Dallas (arriving flight arrived late), then boarded the plane only to deboard immediately afterwards, tire needed to be replaced. Flight supposed to depart at 6:15pm but departed at 9:35pm.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

Everything you need to know for your flight from Guayaquil to Knoxville

Information on your arrival and departure airports