GYE - TYS

$871 Find Cheap Flights from Guayaquil to Knoxville - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$871
Typical prices: $605-$825
American Airlines
Mon 2/19Sun 5/20
GYE - TYS • 2 stops
When to travel
December
Cheapest • 34% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Bogotá El Dorado (BOG)
Cheapest • Avg $333 (round-trip)
Miami (MIA)
Shortest trip • 9h 38m (one-way)
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Flight Deals

Cheap Flights from Guayaquil to Knoxville (GYE-TYS)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Knoxville

Fri, Feb 19 - Thu, May 20
American Airlines Logo
7:11 am - 9:38 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
14h 27m2 stops Miami Washington, D.C. Reagan-National
American Airlines Logo
6:00 am - 1:31 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
8h 31m1 stop Miami
$871American Airlines
Fri, Feb 19 - Thu, May 20
American Airlines Logo
7:11 am - 9:38 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
14h 27m2 stops Miami Washington, D.C. Reagan-National
American Airlines Logo
5:00 am - 1:31 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
9h 31m2 stops Charlotte Douglas Miami
$872American Airlines
Sun, Feb 28 - Thu, May 20
American Airlines Logo
7:11 am - 6:36 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
11h 25m1 stop Miami
American Airlines Logo
6:00 am - 9:02 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
16h 02m1 stop Miami
$880American Airlines
Fri, Feb 19 - Thu, May 20
American Airlines Logo
7:11 am - 6:36 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
11h 25m1 stop Miami
American Airlines Logo
6:00 am - 1:31 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
8h 31m1 stop Miami
$882American Airlines
Sun, Feb 28 - Thu, May 20
American Airlines Logo
3:31 pm - 11:05 amGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
19h 34m2 stops Miami Chicago O'Hare Intl
American Airlines Logo
8:59 am - 9:02 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
13h 03m2 stops Charlotte Douglas Miami
$885American Airlines
Thu, Feb 18 - Thu, May 20
United Airlines Logo
12:21 pm - 1:20 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
24h 59m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
United Airlines Logo
12:00 pm - 12:14 amTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
13h 14m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$908United Airlines
Sun, Feb 28 - Thu, May 20
Delta Logo
5:00 pm - 11:06 amGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
18h 06m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson
Delta Logo
10:05 am - 7:14 amTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
22h 09m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl
$937Delta
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
12:24 pm - 9:57 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
33h 33m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
United Airlines Logo
7:00 am - 5:35 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
34h 35m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$1,021United Airlines
Thu, Nov 5 - Mon, Nov 9
United Airlines Logo
2:47 pm - 9:57 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
31h 10m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
United Airlines Logo
7:00 am - 8:56 pmTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
13h 56m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$1,021United Airlines
Sat, Feb 27 - Thu, May 20
United Airlines Logo
8:26 am - 7:34 pmGYE  Guayaquil Jose Joaquin de Olmedo-TYS Knoxville McGhee Tyson
11h 08m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
United Airlines Logo
7:00 am - 12:14 amTYS  Knoxville McGhee Tyson-GYE Guayaquil Jose Joaquin de Olmedo
18h 14m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$1,058United Airlines
Booking Insights

Price, demand and travel trends for Guayaquil to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Guayaquil to Knoxville with more confidence.

How much is a round-trip flight from Guayaquil to Knoxville?

Round-trip flights from Guayaquil to Knoxville start at $871. Prices are above average for this route right now, with typical round-trip fares ranging from $605 to $825. The lowest price found in the past 5 days was $871 on American Airlines.

What's the cheapest day of the week to fly from Guayaquil to Knoxville?

Wednesday is the cheapest day of the week to fly from Guayaquil to Knoxville, it is 14% cheaper than the average day. Friday is the most expensive day with flight prices 17% higher than average. Based on deals found by KAYAK users in the last 12 months.

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Key details for Guayaquil to Knoxville flights

Low season

July

Cheapest flight

$871
Best time to beat the crowds but there is an average 25% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Guayaquil to Knoxville

When to book flights from Guayaquil to Knoxville

Are your dates flexible? Find out the best times to travel from Guayaquil to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Guayaquil to Knoxville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Guayaquil to Knoxville?

    Flights from Guayaquil to Knoxville usually depart from Guayaquil Jose Joaquin de Olmedo (GYE) and arrive at Knoxville McGhee Tyson (TYS).

  • Which airports do connecting flights from Guayaquil to Knoxville pass through?

    One-stop flights from Guayaquil to Knoxville most commonly connect through:

    • Miami (MIA) - 53% of one-stop connections
    • Fort Lauderdale (FLL) - 44% of one-stop connections
    • Bogotá El Dorado (BOG) - 2% of one-stop connections

    Miami (MIA) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Guayaquil to Knoxville?

    Yes. Being flexible with your travel dates can save you up to 27% on the Guayaquil to Knoxville route. Wednesday is the cheapest departure day at $603 round-trip on average, while Friday is the most expensive at $825, a difference of $222. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Guayaquil to Knoxville?

    There are currently no nonstop flights available from Guayaquil to Knoxville. Flights with 1 layover take between 9h 22m and 13h 47m in total, depending on the connection.

  • Do I need a passport to fly from Guayaquil to Knoxville?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Guayaquil to Knoxville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $871 to $1,247. That means the highest observed fare was about 43% higher than the lowest one.

  • How much time can I save by choosing a different layover airport from Guayaquil to Knoxville?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 9h 22m, compared with 9h 38m via Miami (MIA) and 13h 47m via Fort Lauderdale (FLL).

  • What is the time difference between Guayaquil and Knoxville?

    Knoxville is 1 hour ahead of Guayaquil (Eastern Time vs Ecuador Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

    Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
    · Budget
    · Alamo
    · Thrifty
    · Enterprise Rent-A-Car
    · Payless

  • How much should I expect to pay for a Guayaquil to Knoxville flight?

    Round-trip flights from Guayaquil to Knoxville range from $605 to $825, with an average of $700 over the past 12 months. Anything below $605 counts as a good deal.

Your guide to booking Guayaquil to Knoxville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Wednesday departure instead of Friday. On this route, Wednesday flights average $603 - about $222 less than Friday (27% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Guayaquil to Knoxville trip for December. Fares historically average $465 round-trip in that month - typically $476 less than the most expensive month, which is January (based on the last 12 months).

Everything you need to know for your flight from Guayaquil to Knoxville

Information on your arrival and departure airports

Guayaquil (GYE)
Knoxville (TYS)