GYE - SDQ

$293 Find Cheap Flights from Guayaquil to Santo Domingo - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$422
Typical prices: $434-$507
Avianca
Sun 11/4Mon 11/12
GYE - SDQ • 1 stop
Cheapest one-way
$293
Typical prices: $261-$338
Avianca
Wed 11/14
GYE - SDQ • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Guayaquil and Santo Domingo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 21% compared to booking last minute.
Insights
Insights
When to travel
April
Cheapest • 5% price drop
March
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Punta Cana (PUJ)
Cheapest • Avg $418 (round-trip)
Panama City Tocumen Intl (PTY)
Shortest trip • 6h 56m (one-way)
Insights
Insights
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We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Guayaquil to Santo Domingo (GYE-SDQ)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Guayaquil to Santo Domingo

Wed, Nov 4 - Thu, Nov 12
Avianca Logo
3:30 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
13h 20m1 stop Bogotá El Dorado
Avianca Logo
6:45 pm - 9:05 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
15h 20m2 stops Bogotá El Dorado Quito Mariscal Sucr
$422Avianca
Wed, Nov 25 - Thu, Dec 3
Avianca Logo
3:30 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
13h 20m1 stop Bogotá El Dorado
Avianca Logo
12:45 pm - 8:30 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
8h 45m2 stops Bogotá El Dorado Quito Mariscal Sucr
$422Avianca
Wed, Dec 23 - Thu, Dec 31
Copa Airlines Logo
4:22 am - 1:14 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
7h 52m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:43 pm - 8:57 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
9h 14m1 stop Panama City Tocumen Intl
$422Copa Airlines
Wed, Nov 11 - Wed, Nov 18
Copa Airlines Logo
2:47 pm - 10:58 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
7h 11m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:45 pm - 11:40 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
11h 55m1 stop Panama City Tocumen Intl
$422Copa Airlines
Fri, Nov 6 - Fri, Nov 13
Avianca Logo
7:35 pm - 11:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
15h 15m1 stop Bogotá El Dorado
Avianca Logo
6:45 pm - 9:05 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
15h 20m2 stops Bogotá El Dorado Quito Mariscal Sucr
$422Avianca
Mon, Nov 16 - Mon, Nov 23
Copa Airlines Logo
6:38 pm - 4:12 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
20h 34m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:45 pm - 5:35 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 50m1 stop Panama City Tocumen Intl
$422Copa Airlines
Sat, Nov 7 - Sat, Nov 14
Avianca Logo
7:35 pm - 11:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
15h 15m1 stop Bogotá El Dorado
Avianca Logo
6:45 pm - 9:05 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
15h 20m2 stops Bogotá El Dorado Quito Mariscal Sucr
$422Avianca
Mon, Dec 21 - Fri, Jan 8
Multiple Airlines Logo
2:55 am - 12:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
8h 45m1 stop Punta Cana
Multiple Airlines Logo
6:00 pm - 1:20 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
8h 20m1 stop Punta Cana
$450Multiple Airlines
Fri, Nov 13 - Fri, Nov 20
Multiple Airlines Logo
10:10 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
6h 40m1 stop Bogotá El Dorado
Multiple Airlines Logo
7:06 pm - 11:40 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 34m1 stop Panama City Tocumen Intl
$579Multiple Airlines
Sat, Feb 6 - Tue, Feb 9
JetBlue Logo
2:34 pm - 12:47 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
9h 13m1 stop Fort Lauderdale
JetBlue Logo
6:01 am - 4:29 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
11h 28m1 stop Fort Lauderdale
$629JetBlue
Booking Insights

Price, demand and travel trends for Guayaquil to Santo Domingo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Guayaquil to Santo Domingo?

Round-trip flights from Guayaquil to Santo Domingo typically range from $434 to $507. The lowest price found in the past 5 days was $422, on Avianca.

What's the cheapest day of the week to fly from Guayaquil to Santo Domingo?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Guayaquil to Santo Domingo. It’s 2% cheaper than the average day, while Sunday is the most expensive, with prices 4% higher.

What’s the cheapest month to fly from Guayaquil to Santo Domingo?

•April is the cheapest month to fly from Guayaquil to Santo Domingo at $442 round-trip.
•December ($500) and August ($481) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 13% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Guayaquil to Santo Domingo the cheapest?

Flights from Guayaquil to Santo Domingo are cheapest 6 weeks before departure. Booking in this window typically costs about 21% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Guayaquil to Santo Domingo flights

Low season

July

Cheapest flight

$293
Beat the crowds with an average 26% drop in travelers.
The most popular month to fly with an average 27% increase in travelers.
One-way flight from Guayaquil to Santo Domingo

When to book flights from Guayaquil to Santo Domingo

Are your dates flexible? Find out the best times to travel from Guayaquil to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Guayaquil to Santo Domingo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Guayaquil to Santo Domingo?

    Only Economy Class is available on flights from Guayaquil to Santo Domingo.

  • How long is a flight from Guayaquil to Santo Domingo?

    A nonstop flight from Guayaquil to Santo Domingo takes 00m, covering 1,582 miles.

  • Do I need a passport to fly from Guayaquil to Santo Domingo?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Guayaquil to Santo Domingo flight?

    Round-trip flights from Guayaquil to Santo Domingo range from $434 to $507, with an average of $467 over the past 12 months. Anything below $434 counts as a good deal.

  • How expensive are last-minute Guayaquil to Santo Domingo flights?

    Last-minute fares on this route (booked within two weeks of departure) run 17% above the $467 route average. Book 6 weeks before departure for the lowest fares.

  • Have flight prices from Guayaquil to Santo Domingo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $422 to $1,434. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Guayaquil to Santo Domingo looking right now?

    One-way fares from Guayaquil to Santo Domingo are currently higher than usual. Average one-way flight prices are about $364, which is 29% above the typical average for this route.

  • What car rental options are available at Santo Domingo Las Americas Airport (SDQ)?

    Santo Domingo Las Americas Airport (SDQ) hosts 5 major car rental companies, with daily rates starting from around $7 for economy cars. Top options include:

    • Zezgo
    • America Car Rental
    • JUMBO CAR
    • Infinity Car Rental
    • Final Rentals

  • Which airports can I use when flying from Guayaquil to Santo Domingo?

    Flights from Guayaquil to Santo Domingo usually depart from Guayaquil Jose Joaquin de Olmedo (GYE) and arrive at Santo Domingo Las Americas (SDQ).

  • Which airports do connecting flights from Guayaquil to Santo Domingo pass through?

    One-stop flights from Guayaquil to Santo Domingo most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 61% of one-stop connections
    • Bogotá El Dorado (BOG) - 39% of one-stop connections
    • Fort Lauderdale (FLL) - 0% of one-stop connections
    • Punta Cana (PUJ) - 0% of one-stop connections

  • Can I save money by using flexible dates for flights from Guayaquil to Santo Domingo?

    Yes. Flexible dates can save you up to 6% on flights from Guayaquil to Santo Domingo. Tuesday is the cheapest departure day at $458 round-trip on average, while Sunday is the most expensive at $486, a difference of $28.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Guayaquil to Santo Domingo?

    Flying via Panama City Tocumen Intl (PTY) gives the shortest average 1-stop total travel time at 6h 56m, compared with 7h 24m via Bogotá El Dorado (BOG) and 8h 17m via Punta Cana (PUJ).

  • What is the time difference between Guayaquil and Santo Domingo?

    Santo Domingo is 1 hour ahead of Guayaquil (Atlantic Time vs Ecuador Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santo Domingo?

    Some of the most popular sights in Santo Domingo are Catedral Primada de América, Centro Olimpico Juan Pablo Duarte and Palacio de los Deportes Virgilio Travieso Soto. These are among the most viewed places in Santo Domingo on KAYAK.

Your guide to booking Guayaquil to Santo Domingo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Sunday. On this route, Tuesday flights average $458, about $28 less than Sunday fares (6% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 6 weeks before you fly. On this route, that window historically saves about 21% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Guayaquil to Santo Domingo trip for April. Fares historically average $442 round-trip in that month - typically $58 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santo Domingo Las Americas Airport.

    • Hampton by Hilton Santo Domingo Airport

More options for your flight from Guayaquil to Santo Domingo

Complete your trip to Santo Domingo with a hotel stay or car rental

Car rentals in Santo Domingo
Hotels in Santo Domingo
Vacations in Santo Domingo