SDQ - GYE

$209 Find Cheap Flights from Santo Domingo to Guayaquil

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santo Domingo to Guayaquil departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Guayaquil

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Guayaquil, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santo Domingo to Guayaquil, as well as popular online travel agencies
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41 299 237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$387
Typical prices: $413-$471
Copa Airlines
Tue 5/12Tue 5/19
SDQ - GYE • 1 stop
Cheapest one-way
$189
Typical prices: $197-$269
Avianca
Mon 3/9
SDQ - GYE • 1 stop
Top airlines
Copa Airlines
Cheapest • from $387 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and Guayaquil. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Panama City (PTY)
Cheapest • Avg $481 (round-trip)
Bogotá (BOG)
Shortest trip • 6h 01m (one-way)
Insights
Insights
Insights
Insights
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 9% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
January
Cheapest • 12% price drop
July
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Guayaquil!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Guayaquil (SDQ-GYE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santo Domingo to Guayaquil that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Guayaquil

Tue, May 12 - Tue, May 19
Copa Airlines Logo
8:45 am - 12:01 am
SDQ
-
GYE
16h 16m
1 stop
Copa Airlines Logo
6:00 am - 10:56 pm
GYE
-
SDQ
15h 56m
1 stop
$387Copa Airlines
Thu, Mar 12 - Sun, Mar 22
Copa Airlines Logo
8:48 am - 8:46 pm
SDQ
-
GYE
12h 58m
1 stop
Copa Airlines Logo
12:20 pm - 10:40 pm
GYE
-
SDQ
9h 20m
1 stop
$398Copa Airlines
Wed, Mar 18 - Tue, Mar 31
Avianca Logo
5:45 pm - 9:15 am
SDQ
-
GYE
16h 30m
1 stop
Avianca Logo
9:10 am - 5:55 pm
GYE
-
SDQ
7h 45m
1 stop
$423Avianca
Sat, Mar 21 - Tue, Mar 31
Copa Airlines Logo
11:56 am - 11:55 pm
SDQ
-
GYE
12h 59m
1 stop
Copa Airlines Logo
4:31 am - 4:14 pm
GYE
-
SDQ
10h 43m
1 stop
$425Copa Airlines
Wed, Mar 18 - Tue, Mar 31
Avianca Logo
5:45 pm - 7:40 am
SDQ
-
GYE
14h 55m
2 stops
Avianca Logo
9:10 am - 5:55 pm
GYE
-
SDQ
7h 45m
1 stop
$444Avianca
Wed, Mar 18 - Tue, Mar 31
Avianca Logo
5:45 pm - 1:05 am
SDQ
-
GYE
8h 20m
1 stop
Avianca Logo
9:10 am - 5:55 pm
GYE
-
SDQ
7h 45m
1 stop
$464Avianca
Wed, Mar 18 - Tue, Mar 31
Avianca Logo
5:45 pm - 7:40 am
SDQ
-
GYE
14h 55m
2 stops
Avianca Logo
9:10 am - 5:55 pm
GYE
-
SDQ
7h 45m
1 stop
$468Avianca
Thu, Apr 2 - Sun, Apr 5
Copa Airlines Logo
8:43 am - 8:54 pm
SDQ
-
GYE
13h 11m
1 stop
Copa Airlines Logo
6:33 pm - 11:41 am
GYE
-
SDQ
16h 08m
1 stop
$477Copa Airlines
Fri, Apr 3 - Tue, Apr 7
Avianca Logo
6:50 pm - 7:30 am
SDQ
-
GYE
13h 40m
2 stops
Avianca Logo
4:05 am - 5:55 pm
GYE
-
SDQ
12h 50m
1 stop
$482Avianca
Wed, Mar 18 - Tue, Mar 31
Avianca Logo
5:45 pm - 9:05 am
SDQ
-
GYE
16h 20m
2 stops
Avianca Logo
10:05 am - 5:55 pm
GYE
-
SDQ
6h 50m
1 stop
$484Avianca
Booking Insights

KAYAK's insights & trends for Santo Domingo to Guayaquil flights

Get data-powered insights and trends into flights from Santo Domingo to Guayaquil to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santo Domingo to Guayaquil?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santo Domingo to Guayaquil departing in May.

What is the cheapest month to fly from Santo Domingo to Guayaquil?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santo Domingo to Guayaquil, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santo Domingo to Guayaquil is January, where tickets cost $380 (return) on average. On the other hand, the most expensive months are February and December, where the average cost of round-trip tickets is $448 and $445 respectively.

How far in advance should I book a flight from Santo Domingo to Guayaquil?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santo Domingo to Guayaquil, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santo Domingo to Guayaquil, you should book around 3 weeks before departure, which saves you about 9% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 7 weeks before departure.

Good to know

Low seasonFebruary
Cheapest flight$189
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly and prices are also 3% lower on average.
Flight from Santo Domingo to Guayaquil

When to book flights from Santo Domingo to Guayaquil

Are your dates flexible? Find out the best times to travel from Santo Domingo to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santo Domingo to Guayaquil

  • What is the cheapest flight from Santo Domingo to Guayaquil?

    In the last 3 days, the lowest price for a flight from Santo Domingo to Guayaquil was $189 for a one-way ticket and $387 for a round-trip.

  • Do I need a passport to fly between Santo Domingo and Guayaquil?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santo Domingo and on arrival in Guayaquil.

  • Which airports will I be using when flying from Santo Domingo to Guayaquil?

    When flying out of Santo Domingo you will be using Santo Domingo Las Americas. You will be landing at Guayaquil, also known as Guayaquil Jose Joaquin de Olmedo.

  • Which aircraft models fly most regularly from Santo Domingo to Guayaquil?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santo Domingo to Guayaquil?

    Star Alliance is the only airline alliance operating flights between Santo Domingo and Guayaquil.

  • Which is the best airline for flights from Santo Domingo to Guayaquil, Copa Airlines or Avianca?

    The two airlines most popular with KAYAK users for flights from Santo Domingo to Guayaquil are Copa Airlines and Avianca. With an average price for the route of $439 and an overall rating of 7.5, Copa Airlines is the most popular choice. Avianca is also a great choice for the route, with an average price of $420 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Santo Domingo to Guayaquil?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santo Domingo to Guayaquil.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santo Domingo to Guayaquil?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Guayaquil from Santo Domingo is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santo Domingo to Guayaquil?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Guayaquil with an airline and back to Santo Domingo with another airline. Booking your flights between Santo Domingo and GYE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santo Domingo to Guayaquil?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Guayaquil from Santo Domingo up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santo Domingo to Guayaquil

 
See real verified KAYAK customer reviews for airlines flying from Santo Domingo to Guayaquil. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santo Domingo to Guayaquil? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1559 reviews
7.8Boarding
6.8Food
7.4Comfort
8.1Crew
6.8Entertainment
Airline reviews

Copa staff at PTY and one particular crew member were unhelpful & rude.

6.0 GoodOluwaseyi, Feb 2026
PTY - POS
Read more Copa Airlines reviews

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

horrible service, food was an embarrassment, no charging for cellphones, stay away

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

Great experience with a crew always thinking in the passenger

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

We waited for one hour to deboard the plane after landing. That could be better

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

Everything you need to know for your flight from Santo Domingo to Guayaquil

Information on your arrival and departure airports