SDQ - GYE

$267 Find Cheap Flights from Santo Domingo to Guayaquil - Compare and Save

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Everything you should know

Cheapest round-trip
$379
Typical prices: $435-$531
Multiple Airlines
Tue 12/25Thu 1/4
SDQ - GYE • 1 stop
Cheapest one-way
$267
Typical prices: $224-$305
Avianca
Mon 11/5
SDQ - GYE • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and Guayaquil. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
5 weeks
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 17% compared to booking last minute.
Insights
Insights
When to travel
January
Cheapest • 17% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Fort Lauderdale (FLL)
Cheapest • Avg $428 (round-trip)
Bogotá El Dorado (BOG)
Shortest trip • 6h 31m (one-way)
Insights
Insights
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Cheap Flights from Santo Domingo to Guayaquil (SDQ-GYE)

 

Cheap flights from Santo Domingo to Guayaquil with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Fri, Dec 25 - Mon, Jan 4
Multiple Airlines Logo
6:00 pm - 1:20 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
8h 20m1 stop Punta Cana
Multiple Airlines Logo
2:55 am - 12:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
8h 45m1 stop Punta Cana
$379Multiple Airlines
Fri, Dec 25 - Mon, Jan 4
Multiple Airlines Logo
6:00 pm - 1:20 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
8h 20m1 stop Punta Cana
Multiple Airlines Logo
2:55 am - 12:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
8h 45m1 stop Punta Cana
$388Multiple Airlines
Fri, Dec 18 - Mon, Jan 4
Multiple Airlines Logo
6:00 pm - 1:20 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
8h 20m1 stop Punta Cana
Multiple Airlines Logo
2:55 am - 12:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
8h 45m1 stop Punta Cana
$389Multiple Airlines
Fri, Nov 13 - Fri, Nov 20
Copa Airlines Logo
7:06 pm - 11:18 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
17h 12m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:47 pm - 11:07 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
19h 20m1 stop Panama City Tocumen Intl
$482Copa Airlines
Wed, Nov 11 - Wed, Nov 18
Copa Airlines Logo
12:10 pm - 11:40 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
12h 30m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:25 pm - 11:07 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
21h 42m1 stop Panama City Tocumen Intl
$482Copa Airlines
Sun, Nov 22 - Sun, Nov 29
Copa Airlines Logo
12:45 pm - 5:35 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 50m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:54 am - 1:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
6h 16m1 stop Panama City Tocumen Intl
$482Copa Airlines
Mon, Jan 25 - Mon, Feb 1
Avianca Logo
12:45 pm - 6:25 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
6h 40m1 stop Bogotá El Dorado
Avianca Logo
10:10 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
6h 40m1 stop Bogotá El Dorado
$487Avianca
Fri, Feb 19 - Fri, Feb 26
Avianca Logo
12:45 pm - 11:35 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
11h 50m1 stop Bogotá El Dorado
Avianca Logo
10:10 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
6h 40m1 stop Bogotá El Dorado
$487Avianca
Wed, Apr 7 - Wed, Apr 14
Avianca Logo
6:50 pm - 11:30 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 40m1 stop Bogotá El Dorado
Avianca Logo
6:50 pm - 11:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
16h 00m1 stop Bogotá El Dorado
$487Avianca
Thu, Nov 19 - Wed, Nov 25
Multiple Airlines Logo
5:02 pm - 1:42 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
21h 40m2 stops Miami Panama City Tocumen Intl
Multiple Airlines Logo
4:22 am - 11:07 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
5h 45m1 stop Panama City Tocumen Intl
$684Multiple Airlines

Price, demand and travel trends for Santo Domingo to Guayaquil flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from Santo Domingo to Guayaquil?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Santo Domingo to Guayaquil. It’s 7% cheaper than the average day, while Friday is the most expensive, with prices 4% higher.

What’s the cheapest month to fly from Santo Domingo to Guayaquil?

•January is the cheapest month to fly from Santo Domingo to Guayaquil at $392 round-trip.
•November ($537) and December ($501) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 36% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Santo Domingo to Guayaquil the cheapest?

Flights from Santo Domingo to Guayaquil are cheapest 5 weeks before departure. Booking in this window typically costs about 17% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

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Key details for Santo Domingo to Guayaquil flights

Low season

May

Cheapest flight

$267
Beat the crowds with an average 49% drop in travelers.
The most popular month to fly with an average 37% increase in travelers.
One-way flight from Santo Domingo to Guayaquil

When to book flights from Santo Domingo to Guayaquil

Are your dates flexible? Find out the best times to travel from Santo Domingo to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santo Domingo to Guayaquil flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santo Domingo to Guayaquil?

    Two cabin classes are available on flights from Santo Domingo to Guayaquil:

    • Economy Class
    • Business Class

  • How long is a flight from Santo Domingo to Guayaquil?

    A nonstop flight from Santo Domingo to Guayaquil takes 00m, covering 1,582 miles.

  • Do I need a passport to fly from Santo Domingo to Guayaquil?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santo Domingo to Guayaquil flight?

    Round-trip flights from Santo Domingo to Guayaquil range from $435 to $531, with an average of $472 over the past 12 months. Anything below $435 counts as a good deal.

  • How expensive are last-minute Santo Domingo to Guayaquil flights?

    Last-minute fares on this route (booked within two weeks of departure) run 11% above the $472 route average. Book 5 weeks before departure for the lowest fares.

  • Have flight prices from Santo Domingo to Guayaquil changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $379 to $1,410. That means the highest observed fare was about 4x higher than the lowest one.

  • How are flight prices from Santo Domingo to Guayaquil looking right now?

    One-way fares from Santo Domingo to Guayaquil are currently higher than usual. Average one-way flight prices are about $331, which is 27% above the typical average for this route.

  • What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?

    Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include:

    • Europcar
    • Fox
    • Sixt
    • Alamo
    • keddy by Europcar

  • Which airports can I use when flying from Santo Domingo to Guayaquil?

    Flights from Santo Domingo to Guayaquil usually depart from Santo Domingo Las Americas (SDQ) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

  • Which airports do connecting flights from Santo Domingo to Guayaquil pass through?

    One-stop flights from Santo Domingo to Guayaquil most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 66% of one-stop connections
    • Bogotá El Dorado (BOG) - 33% of one-stop connections
    • Fort Lauderdale (FLL) - 1% of one-stop connections

  • Can I save money by using flexible dates for flights from Santo Domingo to Guayaquil?

    Yes. Flexible dates can save you up to 11% on flights from Santo Domingo to Guayaquil. Tuesday is the cheapest departure day at $439 round-trip on average, while Friday is the most expensive at $492, a difference of $53.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santo Domingo to Guayaquil?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 6h 31m, compared with 6h 53m via Panama City Tocumen Intl (PTY) and 10h 59m via Fort Lauderdale (FLL).

  • What is the time difference between Santo Domingo and Guayaquil?

    Guayaquil is 1 hour behind Santo Domingo (Ecuador Time vs Atlantic Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Santo Domingo to Guayaquil flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Friday. On this route, Tuesday flights average $439, about $53 less than Friday fares (11% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 5 weeks before you fly. On this route, that window historically saves about 17% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santo Domingo to Guayaquil trip for January. Fares historically average $392 round-trip in that month - typically $145 less than the most expensive month, which is November (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Guayaquil Jose Joaquin de Olmedo Airport.

    • Radisson Hotel Guayaquil
    • Wyndham Guayaquil Puerto Santa Ana
    • Hilton Colon Guayaquil

More options for your flight from Santo Domingo to Guayaquil

Complete your trip to Guayaquil with a hotel stay or car rental

Car rentals in Guayaquil
Hotels in Guayaquil