SDQ - GYE

$115 Find Cheap Flights from Santo Domingo to Guayaquil - Compare and Save

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Everything you should know

Cheapest round-trip
$463
Typical prices: $436-$509
Copa Airlines
Sun 10/28Sat 11/3
SDQ - GYE • 1 stop
Cheapest one-way
$115
Typical prices: $214-$300
Multiple Airlines
Fri 11/30
SDQ - GYE • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santo Domingo and Guayaquil. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to book
12 weeks
in advance
Our data shows that travelers who book at least 12 weeks in advance save around 29% compared to booking last minute.
Insights
Insights
When to travel
January
Cheapest • 16% price drop
December
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Fort Lauderdale (FLL)
Cheapest • Avg $428 (round-trip)
Bogotá El Dorado (BOG)
Shortest trip • 6h 32m (one-way)
Insights
Insights
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Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santo Domingo to Guayaquil (SDQ-GYE)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santo Domingo to Guayaquil

Wed, Oct 28 - Tue, Nov 3
Copa Airlines Logo
7:07 pm - 12:01 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 54m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:22 am - 10:58 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
17h 36m1 stop Panama City Tocumen Intl
$463Copa Airlines
Fri, Oct 30 - Fri, Nov 6
Copa Airlines Logo
12:48 pm - 1:40 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
25h 52m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:47 pm - 10:58 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
7h 11m1 stop Panama City Tocumen Intl
$463Copa Airlines
Thu, Oct 29 - Thu, Nov 5
Copa Airlines Logo
8:57 am - 1:40 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 43m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:38 pm - 1:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
17h 32m1 stop Panama City Tocumen Intl
$463Copa Airlines
Tue, Oct 27 - Tue, Nov 3
Copa Airlines Logo
7:07 pm - 12:01 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 54m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:38 pm - 1:10 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
17h 32m1 stop Panama City Tocumen Intl
$463Copa Airlines
Mon, Jan 25 - Mon, Feb 1
Avianca Logo
12:45 pm - 6:25 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
6h 40m1 stop Bogotá El Dorado
Avianca Logo
7:35 pm - 11:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
15h 15m1 stop Bogotá El Dorado
$487Avianca
Sat, Sep 19 - Fri, Sep 25
Avianca Logo
6:50 pm - 8:55 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
15h 05m1 stop Bogotá El Dorado
Avianca Logo
3:30 am - 11:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
7h 20m1 stop Bogotá El Dorado
$487Avianca
Wed, Sep 23 - Tue, Sep 29
Avianca Logo
6:50 pm - 8:55 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
15h 05m1 stop Bogotá El Dorado
Avianca Logo
3:30 am - 11:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
7h 20m1 stop Bogotá El Dorado
$487Avianca
Sat, Feb 6 - Fri, Feb 12
Multiple Airlines Logo
8:54 am - 1:43 pmSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
5h 49m1 stop Panama City Tocumen Intl
Multiple Airlines Logo
3:18 am - 9:45 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
17h 27m2 stops Punta Cana Miami
$601Multiple Airlines
Mon, Nov 16 - Mon, Nov 23
Multiple Airlines Logo
10:56 am - 2:15 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
16h 19m2 stops Miami Punta Cana
Multiple Airlines Logo
10:10 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
6h 40m1 stop Bogotá El Dorado
$606Multiple Airlines
Mon, Nov 16 - Mon, Nov 23
Multiple Airlines Logo
10:56 am - 2:15 amSDQ  Santo Domingo Las Americas-GYE Guayaquil Jose Joaquin de Olmedo
16h 19m2 stops Miami Punta Cana
Multiple Airlines Logo
10:10 am - 5:50 pmGYE  Guayaquil Jose Joaquin de Olmedo-SDQ Santo Domingo Las Americas
6h 40m1 stop Bogotá El Dorado
$616Multiple Airlines
Booking Insights

Price, demand and travel trends for Santo Domingo to Guayaquil flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Santo Domingo to Guayaquil with more confidence.

How much is a round-trip flight from Santo Domingo to Guayaquil?

Round-trip flights from Santo Domingo to Guayaquil start at $463. Prices are typical for this route right now, with typical round-trip fares ranging from $436 to $509. The lowest price found in the past 5 days was $463 on Copa Airlines.

What's the cheapest day of the week to fly from Santo Domingo to Guayaquil?

Tuesday is the cheapest day of the week to fly from Santo Domingo to Guayaquil, it is 6% cheaper than the average day. Saturday is the most expensive day with flight prices 5% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Santo Domingo to Guayaquil?

  • January is the cheapest month to fly from Santo Domingo to Guayaquil at $392 round-trip.
  • November ($502) and May ($495) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 28% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are prices from Santo Domingo to Guayaquil the cheapest?

Flights from Santo Domingo to Guayaquil are cheapest 12 weeks before departure. Booking in this window typically costs about 29% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Key details for Santo Domingo to Guayaquil flights

Low season

May

Cheapest flight

$115
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 5% increase in price.
Flight from Santo Domingo to Guayaquil

When to book flights from Santo Domingo to Guayaquil

Are your dates flexible? Find out the best times to travel from Santo Domingo to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santo Domingo to Guayaquil flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Santo Domingo to Guayaquil?

    Flights from Santo Domingo to Guayaquil usually depart from Santo Domingo Las Americas (SDQ) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

  • What cabin classes can I book on flights from Santo Domingo to Guayaquil?

    Two cabin classes are available on flights from Santo Domingo to Guayaquil:

    • Economy Class
    • Business Class

  • Which airports do connecting flights from Santo Domingo to Guayaquil pass through?

    One-stop flights from Santo Domingo to Guayaquil most commonly connect through:

    • Panama City Tocumen Intl (PTY) - 65% of one-stop connections
    • Bogotá El Dorado (BOG) - 34% of one-stop connections
    • Fort Lauderdale (FLL) - 1% of one-stop connections

    Panama City Tocumen Intl (PTY) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Santo Domingo to Guayaquil?

    Yes. Being flexible with your travel dates can save you up to 11% on the Santo Domingo to Guayaquil route. Tuesday is the cheapest departure day at $439 round-trip on average, while Saturday is the most expensive at $491, a difference of $52. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How expensive are last-minute Santo Domingo to Guayaquil flights?

    Last-minute fares on this route - booked within 2 weeks of departure - run 14% above the route average of $466. Book 12 weeks before departure for the lowest fares.

  • How long is a flight from Santo Domingo to Guayaquil?

    A nonstop flight from Santo Domingo to Guayaquil takes 0h 00m, covering 1,582 miles.

  • Do I need a passport to fly from Santo Domingo to Guayaquil?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • Have flight prices from Santo Domingo to Guayaquil changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $463 to $1,323. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Santo Domingo to Guayaquil looking right now?

    One-way fares from Santo Domingo to Guayaquil are currently lower than usual. Average one-way flight prices are about $209, which is 14% below the typical average for this route.

  • How much time can I save by choosing a different layover airport from Santo Domingo to Guayaquil?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 6h 32m, compared with 6h 46m via Panama City Tocumen Intl (PTY) and 10h 59m via Fort Lauderdale (FLL).

  • What is the time difference between Santo Domingo and Guayaquil?

    Guayaquil is 1 hour behind Santo Domingo (Ecuador Time vs Atlantic Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?

    Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include:
    · Europcar
    · Fox
    · Sixt
    · Alamo
    · keddy by Europcar

  • How much should I expect to pay for a Santo Domingo to Guayaquil flight?

    Round-trip flights from Santo Domingo to Guayaquil range from $436 to $509, with an average of $466 over the past 12 months. Anything below $436 counts as a good deal.

Your guide to booking Santo Domingo to Guayaquil flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Tuesday departure instead of Saturday. On this route, Tuesday flights average $439 - about $52 less than Saturday (11% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 12 weeks before you fly. On this route, that window historically saves about 29% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Santo Domingo to Guayaquil trip for January. Fares historically average $392 round-trip in that month - typically $110 less than the most expensive month, which is November (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Guayaquil Jose Joaquin de Olmedo Airport.
    - Sheraton Guayaquil Hotel
    - Radisson Hotel Guayaquil
    - Wyndham Guayaquil Puerto Santa Ana

More options for your flight from Santo Domingo to Guayaquil

Complete your trip to Guayaquil with a hotel stay or car rental

Car rentals in Guayaquil
Hotels in Guayaquil