Which airports can I use when flying from Harrisburg to Knoxville?

Flights from Harrisburg to Knoxville usually depart from Harrisburg (MDT) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Harrisburg to Knoxville?

Two cabin classes are available on flights from Harrisburg to Knoxville: • Economy Class • First Class

Which airports do connecting flights from Harrisburg to Knoxville pass through?

One-stop flights from Harrisburg to Knoxville most commonly connect through: • Charlotte Douglas (CLT) - 34% of one-stop connections • Washington, D.C. Dulles Intl (IAD) - 24% of one-stop connections • Philadelphia (PHL) - 20% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 15% of one-stop connections

Can I save money by using flexible dates for flights from Harrisburg to Knoxville?

Yes. Flexible dates can save you up to 33% on flights from Harrisburg to Knoxville. Tuesday is the cheapest departure day at $312 round-trip on average, while Wednesday is the most expensive at $459, a difference of $147. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Harrisburg to Knoxville?

A nonstop flight from Harrisburg to Knoxville takes 00m, covering 496 miles.

Do I need a passport to fly from Harrisburg to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Harrisburg to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $319 to $1,603. That means the highest observed fare was about 5x higher than the lowest one.

How much time can I save by choosing a different layover airport from Harrisburg to Knoxville?

Flying via Washington, D.C. Dulles Intl (IAD) gives the shortest average 1-stop total travel time at 4h 13m, compared with 4h 16m via Detroit Metropolitan Wayne County (DTW) and 4h 21m via Charlotte Douglas (CLT).

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include: • Budget • Alamo • Enterprise Rent-A-Car • Thrifty • Avis

How much should I expect to pay for a Harrisburg to Knoxville flight?

Round-trip flights from Harrisburg to Knoxville range from $312 to $513, with an average of $386 over the past 12 months. Anything below $312 counts as a good deal.

How much is a round-trip flight from Harrisburg to Knoxville?

Round-trip flights from Harrisburg to Knoxville typically range from $312 to $513. The lowest price found in the past 5 days was $319, on American Airlines.

Which airline is the cheapest to fly from Harrisburg to Knoxville?

American Airlines ($319) and United Airlines ($319) are the cheapest airlines to fly round-trip from Harrisburg to Knoxville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Harrisburg to Knoxville?

Charlotte Douglas (CLT) is the most popular layover for the Harrisburg to Knoxville route. 34% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via CLT.

What is the cheapest layover airport when flying from Harrisburg to Knoxville?

Flights via Orlando Sanford Intl (SFB) offer the most affordable fares, with an average round-trip price of $277. Based on KAYAK data over the past 3 months.

When flying from Harrisburg to Knoxville which airport offers the shortest layover?

Detroit Metropolitan Wayne County (DTW) had the shortest average connection time for Harrisburg to Knoxville layovers at 2h 34m over the past 3 months.

$319 CHEAP FLIGHTS from Harrisburg to Knoxville (MDT - TYS)

Save 19% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$319

Typical prices: $312-$513

American Airlines

Wed 11/7Wed 11/14

MDT - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Harrisburg and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

January

Cheapest • 30% price drop

January

Most popular

Good to know

Top layover airports

Orlando Sanford Intl (SFB)

Cheapest • Avg $277 (round-trip)

Washington, D.C. Dulles Intl (IAD)

Shortest trip • 4h 13m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Knoxville!

Cheap Flights from Harrisburg to Knoxville (MDT-TYS)

Cheap flights from Harrisburg to Knoxville with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Round-trip

One-way

Last minute

Sat, Nov 7 - Sat, Nov 14

2:56 pm - 8:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 53m1 stop Philadelphia

7:50 am - 2:31 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

6h 41m1 stop Philadelphia

$319American Airlines

Sat, Nov 14 - Tue, Nov 17

6:15 am - 11:30 amMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 15m1 stop Washington, D.C. Dulles Intl

1:56 pm - 6:57 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

5h 01m1 stop Chicago O'Hare Intl

$319United Airlines

Sat, Nov 14 - Tue, Nov 17

6:15 am - 11:30 amMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 15m1 stop Washington, D.C. Dulles Intl

6:45 am - 1:58 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 13m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$324United Airlines

Sat, Nov 14 - Tue, Nov 17

6:15 am - 3:52 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

9h 37m2 stops Washington, D.C. Dulles Intl Newark

4:30 pm - 11:44 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 14m2 stops Newark Washington, D.C. Dulles Intl

$344United Airlines

Tue, Oct 27 - Sat, Oct 31

9:34 am - 1:33 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

3h 59m1 stop Charlotte Douglas

6:00 am - 10:17 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 17m1 stop Philadelphia

$349American Airlines

Sat, Nov 7 - Sat, Nov 14

8:15 am - 1:13 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 58m1 stop Chicago O'Hare Intl

6:45 am - 1:58 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 13m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$352United Airlines

Fri, Oct 23 - Sun, Oct 25

12:18 pm - 5:35 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 17m1 stop Philadelphia

6:00 am - 11:42 amTYS Knoxville McGhee Tyson-MDT Harrisburg

5h 42m1 stop Philadelphia

$369American Airlines

Sat, Nov 7 - Sat, Nov 14

6:15 am - 1:13 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 58m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

6:45 am - 1:58 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 13m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$380United Airlines

Wed, Nov 25 - Sat, Nov 28

6:15 am - 11:21 amMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 06m1 stop Philadelphia

7:50 am - 1:32 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

5h 42m1 stop Philadelphia

$407American Airlines

Tue, Feb 2 - Sat, Feb 6

6:20 am - 1:20 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

7h 00m1 stop Chicago O'Hare Intl

1:55 pm - 8:49 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

6h 54m1 stop Chicago O'Hare Intl

$409United Airlines

Thu, Oct 15 - Mon, Oct 19

10:02 am - 3:12 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 10m1 stop Charlotte Douglas

6:05 pm - 10:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 54m1 stop Philadelphia

$399American Airlines

Thu, Oct 15 - Mon, Oct 19

10:02 am - 3:12 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 10m1 stop Charlotte Douglas

7:58 pm - 12:24 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 26m1 stop Charlotte Douglas

$454American Airlines

Thu, Oct 15 - Mon, Oct 19

10:02 am - 3:12 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 10m1 stop Charlotte Douglas

7:58 pm - 12:24 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 26m1 stop Charlotte Douglas

$500American Airlines

Thu, Oct 15 - Mon, Oct 19

8:24 am - 3:12 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 48m1 stop Charlotte Douglas

7:58 pm - 12:24 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 26m1 stop Charlotte Douglas

$612American Airlines

Thu, Oct 15 - Mon, Oct 19

6:15 am - 1:14 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 59m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

7:25 pm - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

18h 34m1 stop Washington, D.C. Dulles Intl

$869United Airlines

Thu, Oct 15 - Mon, Oct 19

6:15 am - 1:14 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 59m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

7:25 pm - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

18h 34m1 stop Washington, D.C. Dulles Intl

$873United Airlines

Thu, Oct 15 - Mon, Oct 19

6:15 am - 1:14 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 59m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

1:55 pm - 9:32 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 37m1 stop Chicago O'Hare Intl

$890United Airlines

Thu, Oct 15 - Mon, Oct 19

6:15 am - 1:14 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 59m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

4:16 pm - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

21h 43m2 stops Newark Washington, D.C. Dulles Intl

$914United Airlines

Thu, Oct 15 - Mon, Oct 19

6:15 am - 10:37 amMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 22m1 stop Washington, D.C. Dulles Intl

6:03 pm - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

19h 56m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$919United Airlines

Thu, Oct 15 - Mon, Oct 19

6:30 am - 1:14 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 44m1 stop Chicago O'Hare Intl

6:03 pm - 1:59 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

19h 56m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$919United Airlines

Price, demand and travel trends for Harrisburg to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Harrisburg to Knoxville? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Harrisburg to Knoxville departing in november.

Find deals

Low season	October
High season	January
Cheapest flight	$319

Round-trip flight from Harrisburg to Knoxville

When to book flights from Harrisburg to Knoxville

Are your dates flexible? Find out the best times to travel from Harrisburg to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Harrisburg to Knoxville?
Two cabin classes are available on flights from Harrisburg to Knoxville:

• Economy Class
• First Class
How long is a flight from Harrisburg to Knoxville?
A nonstop flight from Harrisburg to Knoxville takes 00m, covering 496 miles.
Do I need a passport to fly from Harrisburg to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Harrisburg to Knoxville flight?
Round-trip flights from Harrisburg to Knoxville range from $312 to $513, with an average of $386 over the past 12 months. Anything below $312 counts as a good deal.
Have flight prices from Harrisburg to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $319 to $1,603. That means the highest observed fare was about 5x higher than the lowest one.
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:

• Budget
• Alamo
• Enterprise Rent-A-Car
• Thrifty
• Avis
Which airports can I use when flying from Harrisburg to Knoxville?
Flights from Harrisburg to Knoxville usually depart from Harrisburg (MDT) and arrive at Knoxville McGhee Tyson (TYS).
Which airports do connecting flights from Harrisburg to Knoxville pass through?
One-stop flights from Harrisburg to Knoxville most commonly connect through:

• Charlotte Douglas (CLT) - 34% of one-stop connections
• Washington, D.C. Dulles Intl (IAD) - 24% of one-stop connections
• Philadelphia (PHL) - 20% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 15% of one-stop connections
Can I save money by using flexible dates for flights from Harrisburg to Knoxville?
Yes. Flexible dates can save you up to 33% on flights from Harrisburg to Knoxville. Tuesday is the cheapest departure day at $312 round-trip on average, while Wednesday is the most expensive at $459, a difference of $147.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Harrisburg to Knoxville?
Flying via Washington, D.C. Dulles Intl (IAD) gives the shortest average 1-stop total travel time at 4h 13m, compared with 4h 16m via Detroit Metropolitan Wayne County (DTW) and 4h 21m via Charlotte Douglas (CLT).

If your dates are flexible, aim for a Tuesday departure and avoid flying on Wednesday. On this route, Tuesday flights average $312, about $147 less than Wednesday fares (32% savings) based on the last 12 months.
If you can choose when to travel, plan your Harrisburg to Knoxville trip for January. Fares historically average $271 round-trip in that month - typically $441 less than the most expensive month, which is March (based on the last 12 months).

More options for your flight from Harrisburg to Knoxville

Add a hotel or car rental

Airports

Cabin class

Direct Flights

Origins

Other destinations

Return flight

Complete your trip to Knoxville with a hotel stay or car rental

Car rentals in Knoxville

Hotels in Knoxville

Vacations in Knoxville

MDT - TYS

$319 Find Cheap Flights from Harrisburg to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Harrisburg to Knoxville (MDT-TYS)

Cheap flights from Harrisburg to Knoxville with top airlines, updated regularly. Compare round-trip, one-way, direct and last-minute deals.

Price, demand and travel trends for Harrisburg to Knoxville flights

How much is a round-trip flight from Harrisburg to Knoxville?

Which airline is the cheapest to fly from Harrisburg to Knoxville?

What’s the most popular layover airport when flying from Harrisburg to Knoxville?

What is the cheapest layover airport when flying from Harrisburg to Knoxville?

When flying from Harrisburg to Knoxville which airport offers the shortest layover?

Key details for Harrisburg to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Harrisburg to Knoxville

Your Harrisburg to Knoxville flight questions, answered

Your guide to booking Harrisburg to Knoxville flights

More options for your flight from Harrisburg to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Harrisburg to Knoxville

Find direct flights to and from Harrisburg and Knoxville

Flights from domestic origins to Knoxville

Flights to other popular destinations

Find deals for your return flight