Which airports can I use when flying from Harrisburg to Knoxville?

Flights from Harrisburg to Knoxville usually depart from Harrisburg (MDT) and arrive at Knoxville McGhee Tyson (TYS).

What cabin classes can I book on flights from Harrisburg to Knoxville?

Two cabin classes are available on flights from Harrisburg to Knoxville: • Economy Class • First Class

Which airports do connecting flights from Harrisburg to Knoxville pass through?

One-stop flights from Harrisburg to Knoxville most commonly connect through: • Charlotte Douglas (CLT) - 30% of one-stop connections • Philadelphia (PHL) - 30% of one-stop connections • Washington, D.C. Dulles Intl (IAD) - 19% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 11% of one-stop connections Charlotte Douglas (CLT) handles the largest share of one-stop connections on this route.

Can I save money by using flexible dates for flights from Harrisburg to Knoxville?

Yes. Being flexible with your travel dates can save you up to 35% on the Harrisburg to Knoxville route. Tuesday is the cheapest departure day at $312 round-trip on average, while Wednesday is the most expensive at $476, a difference of $164. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Harrisburg to Knoxville?

A nonstop flight from Harrisburg to Knoxville takes 0h 00m, covering 496 miles.

Do I need a passport to fly from Harrisburg to Knoxville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Harrisburg to Knoxville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $299 to $1,108. That means the highest observed fare was about 4x higher than the lowest one.

How are flight prices from Harrisburg to Knoxville looking right now?

One-way fares from Harrisburg to Knoxville are currently higher than usual. Average one-way flight prices are about $349, which is 16% above the typical average for this route.

How much time can I save by choosing a different layover airport from Harrisburg to Knoxville?

Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 08m, compared with 4h 13m via Washington, D.C. Dulles Intl (IAD) and 4h 26m via Philadelphia (PHL).

What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?

Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include: · Budget · Alamo · Thrifty · Enterprise Rent-A-Car · Payless

How much should I expect to pay for a Harrisburg to Knoxville flight?

Round-trip flights from Harrisburg to Knoxville range from $312 to $492, with an average of $392 over the past 12 months. Anything below $312 counts as a good deal.

What is the cheapest airline to fly from Harrisburg to Knoxville?

American Airlines ($299) and Delta ($329) are the cheapest airlines to fly round-trip from Harrisburg to Knoxville according to KAYAK data over the last 5 days.

What is the most popular layover airport when flying from Harrisburg to Knoxville?

Charlotte Douglas (CLT) and Philadelphia (PHL) are the most popular layovers for the Harrisburg to Knoxville route. 30% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via CLT or PHL.

What is the cheapest layover airport when flying from Harrisburg to Knoxville?

Flights via Orlando Sanford Intl (SFB) offer the most affordable fares, with an average round-trip price of $277. Based on KAYAK data over the past 3 months.

When flying from Harrisburg to Knoxville which airport offers the shortest layover?

Detroit Metropolitan Wayne County (DTW) had the shortest average connection time for Harrisburg to Knoxville layovers at 149 minutes over the past 3 months.

$176 CHEAP FLIGHTS from Harrisburg to Knoxville (MDT - TYS)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$299

Typical prices: $312-$492

American Airlines

Fri 9/28Fri 10/5

MDT - TYS • 1 stop

Cheapest one-way

$176

Typical prices: $158-$344

Allegiant Air

Mon 9/24

MDT - TYS • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Harrisburg and Knoxville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

January

Cheapest • 31% price drop

November

Most popular

Good to know

Top layover airports

Orlando Sanford Intl (SFB)

Cheapest • Avg $277 (round-trip)

Detroit Metropolitan Wayne County (DTW)

Shortest trip • 4h 08m (one-way)

Insights

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We hope you love your trip to Knoxville!

Flight Deals

Cheap Flights from Harrisburg to Knoxville (MDT-TYS)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Harrisburg to Knoxville

Mon, Sep 28 - Mon, Oct 5

5:45 am - 11:43 amMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 58m1 stop Philadelphia

7:58 pm - 12:24 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 26m1 stop Charlotte Douglas

$299American Airlines

Wed, Dec 2 - Tue, Dec 8

2:56 pm - 8:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 53m1 stop Philadelphia

12:42 pm - 7:02 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

6h 20m1 stop Philadelphia

$299American Airlines

Thu, Dec 3 - Wed, Dec 9

9:36 am - 3:27 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 51m1 stop Philadelphia

6:01 am - 10:17 amTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 16m1 stop Charlotte Douglas

$299American Airlines

Sat, Sep 12 - Wed, Sep 16

6:09 pm - 10:27 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 18m1 stop Atlanta Hartsfield-Jackson

5:40 am - 11:03 amTYS Knoxville McGhee Tyson-MDT Harrisburg

5h 23m1 stop Atlanta Hartsfield-Jackson

$329Delta

Tue, Sep 15 - Sat, Sep 19

5:54 pm - 12:23 amMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 29m1 stop Chicago O'Hare Intl

7:20 pm - 11:30 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 10m1 stop Washington, D.C. Dulles Intl

$329United Airlines

Fri, Sep 11 - Tue, Sep 15

5:54 pm - 10:49 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 55m1 stop Chicago O'Hare Intl

7:20 pm - 11:30 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 10m1 stop Washington, D.C. Dulles Intl

$329United Airlines

Tue, Sep 15 - Sat, Sep 19

7:59 pm - 11:59 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 00m1 stop Washington, D.C. Dulles Intl

6:00 am - 1:39 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 39m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$334United Airlines

Mon, Oct 12 - Thu, Oct 15

8:29 pm - 5:50 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

21h 21m1 stop Orlando Sanford Intl

9:28 pm - 8:23 amTYS Knoxville McGhee Tyson-MDT Harrisburg

10h 55m1 stop Tampa St. Petersburg

$354Allegiant Air

Thu, Oct 29 - Sun, Nov 1

8:51 pm - 2:09 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

17h 18m1 stop Orlando Sanford Intl

10:00 pm - 10:13 amTYS Knoxville McGhee Tyson-MDT Harrisburg

12h 13m1 stop Tampa St. Petersburg

$357Allegiant Air

Sat, Sep 19 - Mon, Sep 21

6:09 pm - 10:27 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 18m1 stop Atlanta Hartsfield-Jackson

7:25 pm - 11:40 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 15m1 stop Atlanta Hartsfield-Jackson

$383Delta

Recent last minute flight deals from Harrisburg to Knoxville

Sat, Sep 5 - Mon, Sep 7

2:17 pm - 8:53 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 36m1 stop Chicago O'Hare Intl

5:45 am - 9:37 amTYS Knoxville McGhee Tyson-MDT Harrisburg

3h 52m1 stop Washington, D.C. Dulles Intl

$369United Airlines

Sat, Sep 5 - Tue, Sep 8

3:28 pm - 9:50 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

6h 22m1 stop Charlotte Douglas

6:32 pm - 11:03 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 31m1 stop Philadelphia

$379American Airlines

Fri, Sep 4 - Mon, Sep 7

7:59 pm - 11:59 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 00m1 stop Washington, D.C. Dulles Intl

5:45 am - 9:37 amTYS Knoxville McGhee Tyson-MDT Harrisburg

3h 52m1 stop Washington, D.C. Dulles Intl

$440United Airlines

Sat, Sep 5 - Tue, Sep 8

11:53 am - 5:35 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

5h 42m2 stops Philadelphia Charlotte Douglas

7:25 pm - 11:28 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

4h 03m1 stop Charlotte Douglas

$483American Airlines

Sat, Sep 5 - Mon, Sep 7

10:57 am - 8:53 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

9h 56m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

5:45 am - 9:37 amTYS Knoxville McGhee Tyson-MDT Harrisburg

3h 52m1 stop Washington, D.C. Dulles Intl

$530United Airlines

Fri, Sep 4 - Mon, Sep 7

7:59 pm - 11:59 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

4h 00m1 stop Washington, D.C. Dulles Intl

5:45 am - 8:58 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

15h 13m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$764United Airlines

Sat, Sep 5 - Tue, Sep 8

2:17 pm - 11:59 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

9h 42m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:00 am - 1:39 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 39m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$793United Airlines

Sat, Sep 5 - Mon, Sep 7

10:57 am - 8:53 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

9h 56m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

5:45 am - 4:52 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

11h 07m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$876United Airlines

Fri, Sep 4 - Mon, Sep 7

6:15 am - 4:58 pmMDT Harrisburg-TYS Knoxville McGhee Tyson

10h 43m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

7:00 am - 2:03 pmTYS Knoxville McGhee Tyson-MDT Harrisburg

7h 03m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

$1,544United Airlines

Booking Insights

Price, demand and travel trends for Harrisburg to Knoxville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Harrisburg to Knoxville with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Harrisburg to Knoxville?

Round-trip flights from Harrisburg to Knoxville start at $299. Prices are below average for this route right now, with typical round-trip fares ranging from $312 to $492. The lowest price found in the past 5 days was $299 on American Airlines.

What's the cheapest day of the week to fly from Harrisburg to Knoxville?

Tuesday is the cheapest day of the week to fly from Harrisburg to Knoxville, it is 21% cheaper than the average day. Wednesday is the most expensive day with flight prices 21% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Harrisburg to Knoxville?

January is the cheapest month to fly from Harrisburg to Knoxville at $271 round-trip.
March ($712) and August ($699) are the most expensive months.
The price difference between flying in the cheapest and most expensive months is 162% on average.

This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	April
High season	November
Cheapest flight	$176

Best time to beat the crowds with an average 9% drop in price.

Most popular time to fly with an average 20% increase in price.

Flight from Harrisburg to Knoxville

When to book flights from Harrisburg to Knoxville

Are your dates flexible? Find out the best times to travel from Harrisburg to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Harrisburg to Knoxville?
Flights from Harrisburg to Knoxville usually depart from Harrisburg (MDT) and arrive at Knoxville McGhee Tyson (TYS).
What cabin classes can I book on flights from Harrisburg to Knoxville?
Two cabin classes are available on flights from Harrisburg to Knoxville:

• Economy Class
• First Class
Which airports do connecting flights from Harrisburg to Knoxville pass through?
One-stop flights from Harrisburg to Knoxville most commonly connect through:

• Charlotte Douglas (CLT) - 30% of one-stop connections
• Philadelphia (PHL) - 30% of one-stop connections
• Washington, D.C. Dulles Intl (IAD) - 19% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 11% of one-stop connections

Charlotte Douglas (CLT) handles the largest share of one-stop connections on this route.
Can I save money by using flexible dates for flights from Harrisburg to Knoxville?
Yes. Being flexible with your travel dates can save you up to 35% on the Harrisburg to Knoxville route. Tuesday is the cheapest departure day at $312 round-trip on average, while Wednesday is the most expensive at $476, a difference of $164. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How long is a flight from Harrisburg to Knoxville?
A nonstop flight from Harrisburg to Knoxville takes 0h 00m, covering 496 miles.
Do I need a passport to fly from Harrisburg to Knoxville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from Harrisburg to Knoxville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $299 to $1,108. That means the highest observed fare was about 4x higher than the lowest one.
How are flight prices from Harrisburg to Knoxville looking right now?
One-way fares from Harrisburg to Knoxville are currently higher than usual. Average one-way flight prices are about $349, which is 16% above the typical average for this route.
How much time can I save by choosing a different layover airport from Harrisburg to Knoxville?
Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 08m, compared with 4h 13m via Washington, D.C. Dulles Intl (IAD) and 4h 26m via Philadelphia (PHL).
What car rental options are available at Knoxville McGhee Tyson Airport (TYS)?
Knoxville McGhee Tyson Airport (TYS) hosts 5 major car rental companies, with daily rates starting from around $33 for economy cars. Top options include:
· Budget
· Alamo
· Thrifty
· Enterprise Rent-A-Car
· Payless
How much should I expect to pay for a Harrisburg to Knoxville flight?
Round-trip flights from Harrisburg to Knoxville range from $312 to $492, with an average of $392 over the past 12 months. Anything below $312 counts as a good deal.

If your dates can be flexible, aim for a Tuesday departure instead of Wednesday. On this route, Tuesday flights average $312 - about $164 less than Wednesday (34% savings) based on the last 12 months.
If you can choose when to travel, plan your Harrisburg to Knoxville trip for January. Fares historically average $271 round-trip in that month - typically $441 less than the most expensive month, which is March (based on the last 12 months).

Everything you need to know for your flight from Harrisburg to Knoxville

Airports

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Complete your trip

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Return flight deals

Information on your arrival and departure airports

Harrisburg (MDT)

Knoxville (TYS)

MDT - TYS

$176 Find Cheap Flights from Harrisburg to Knoxville - Compare and Save

Everything you should know

Cheap Flights from Harrisburg to Knoxville (MDT-TYS)

Recent round-trip flight deals from Harrisburg to Knoxville

Recent one-way flight deals from Harrisburg to Knoxville

Recent last minute flight deals from Harrisburg to Knoxville

Price, demand and travel trends for Harrisburg to Knoxville flights

How much is a round-trip flight from Harrisburg to Knoxville?

What's the cheapest day of the week to fly from Harrisburg to Knoxville?

What is the cheapest month to fly from Harrisburg to Knoxville?

What is the cheapest airline to fly from Harrisburg to Knoxville?

What is the most popular layover airport when flying from Harrisburg to Knoxville?

What is the cheapest layover airport when flying from Harrisburg to Knoxville?

When flying from Harrisburg to Knoxville which airport offers the shortest layover?

Key details for Harrisburg to Knoxville flights

Low season

High season

Cheapest flight

When to book flights from Harrisburg to Knoxville

Your Harrisburg to Knoxville flight questions, answered

Your guide to booking Harrisburg to Knoxville flights

Everything you need to know for your flight from Harrisburg to Knoxville

Information on your arrival and departure airports

Cabin class types available on flights from Harrisburg to Knoxville

Complete your trip to Knoxville with a hotel stay or car rental

Find direct flights to and from Harrisburg and Knoxville

Flights to other popular destinations

Flights from domestic origins to Knoxville

Choose which airport to fly into in Knoxville

Find deals for your return flight