MDT - TYS

$149 Find Cheap Flights from Harrisburg to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to Knoxville departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Knoxville, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$254
Overall average: $418
United Airlines
Tue 2/10Tue 2/17
MDT - TYS • 1 stop
Cheapest one-way
$146
Typical prices: $354-$499
Allegiant Air
Mon 4/6
MDT - TYS • 1 stop
When to travel
May
Cheapest • 31% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Harrisburg to Knoxville (MDT-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to Knoxville

Tue, Feb 10 - Tue, Feb 17
United Airlines Logo
6:15 am - 10:57 am
MDT
-
TYS
4h 42m
1 stop
United Airlines Logo
9:40 am - 1:56 pm
TYS
-
MDT
4h 16m
1 stop
$254United Airlines
Thu, Jan 29 - Sat, Jan 31
United Airlines Logo
6:15 am - 10:57 am
MDT
-
TYS
4h 42m
1 stop
United Airlines Logo
1:59 pm - 9:05 pm
TYS
-
MDT
7h 06m
1 stop
$259United Airlines
Sat, Feb 14 - Sun, Feb 15
United Airlines Logo
2:07 pm - 8:37 pm
MDT
-
TYS
6h 30m
1 stop
United Airlines Logo
6:45 am - 1:56 pm
TYS
-
MDT
7h 11m
2 stops
$262United Airlines
Thu, Jan 29 - Mon, Feb 2
United Airlines Logo
6:15 am - 10:57 am
MDT
-
TYS
4h 42m
1 stop
United Airlines Logo
6:45 am - 1:51 pm
TYS
-
MDT
7h 06m
2 stops
$264United Airlines
Thu, Mar 12 - Wed, Mar 18
American Airlines Logo
6:00 am - 10:48 am
MDT
-
TYS
4h 48m
1 stop
American Airlines Logo
4:02 pm - 10:18 pm
TYS
-
MDT
6h 16m
1 stop
$269American Airlines
Thu, Mar 12 - Thu, Mar 19
American Airlines Logo
6:00 am - 10:48 am
MDT
-
TYS
4h 48m
1 stop
American Airlines Logo
4:02 pm - 10:32 pm
TYS
-
MDT
6h 30m
1 stop
$273American Airlines
Tue, Apr 14 - Fri, Apr 17
Delta Logo
6:00 am - 10:06 am
MDT
-
TYS
4h 06m
1 stop
Delta Logo
5:30 pm - 10:52 pm
TYS
-
MDT
5h 22m
1 stop
$297Delta
Wed, Jan 28 - Sat, Jan 31
Delta Logo
6:10 am - 12:13 pm
MDT
-
TYS
6h 03m
1 stop
Delta Logo
5:00 pm - 11:26 pm
TYS
-
MDT
6h 26m
1 stop
$299Delta
Thu, Jan 29 - Mon, Feb 2
United Airlines Logo
6:15 am - 1:24 pm
MDT
-
TYS
7h 09m
2 stops
United Airlines Logo
6:45 am - 1:51 pm
TYS
-
MDT
7h 06m
2 stops
$313United Airlines
Tue, Feb 3 - Sat, Feb 7
United Airlines Logo
6:15 am - 10:57 am
MDT
-
TYS
4h 42m
1 stop
United Airlines Logo
6:45 am - 2:15 pm
TYS
-
MDT
7h 30m
1 stop
$314United Airlines
Booking Insights

KAYAK's insights & trends for Harrisburg to Knoxville flights

Get data-powered insights and trends into flights from Harrisburg to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Harrisburg to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Harrisburg to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Harrisburg to Knoxville is May, where tickets cost $288 (return) on average. On the other hand, the most expensive months are September and January, where the average cost of round-trip tickets is $572 and $557 respectively.

Find deals

Good to know

Low seasonApril
Cheapest flight$146
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 37% increase in price.
Flight from Harrisburg to Knoxville

When to book flights from Harrisburg to Knoxville

Are your dates flexible? Find out the best times to travel from Harrisburg to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Harrisburg to Knoxville

  • What is the cheapest flight from Harrisburg to Knoxville?

    In the last 3 days, the lowest price for a flight from Harrisburg to Knoxville was $146 for a one-way ticket and $254 for a round-trip.

  • Do I need a passport to fly between Harrisburg and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Harrisburg to Knoxville?

    Harrisburg and Knoxville are both served by 1 main airport. You will leave Harrisburg from Harrisburg and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Harrisburg to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Harrisburg to Knoxville?

    oneworld is the only airline alliance operating flights between Harrisburg and Knoxville.

  • How does KAYAK find such low prices on flights from Harrisburg to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Harrisburg is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Harrisburg with another airline. Booking your flights between Harrisburg and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Harrisburg up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Harrisburg to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11119 reviews
6.4Food
7.5Boarding
6.9Entertainment
7.2Comfort
8.0Crew
Airline reviews

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

10.0 ExcellentJill, Jan 2026
PHL - LAX
Read more American Airlines reviews

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

The pilot greased the landing and the crew was fantastic.

delayed due to weather. Could not communicate with family since the wifi was broken

Delays to take off and to leave the plane after landing added a lot of time to this flight.

The Phildalphia to Allentown portion was a BUS, not a plane. All was as expected.

Excellent - explanations were clear staff was nice and flight was comfortable

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

Did not get the seat I selected and paid for.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

Everything you need to know for your flight from Harrisburg to Knoxville

Information on your arrival and departure airports

Harrisburg (MDT)
Knoxville (TYS)