MDT - TYS

$140 Find Cheap Flights from Harrisburg to Knoxville

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to Knoxville departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Knoxville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Knoxville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Knoxville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$229
Overall average: $418
United Airlines
Tue 1/20Sat 1/24
MDT - TYS • 1 stop
Cheapest one-way
$140
Overall average: $148
Allegiant Air
Thu 12/18
MDT - TYS • 1 stop
Top airlines
United Airlines
Cheapest • from $229 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
May
Cheapest • 28% price drop
September
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Knoxville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Harrisburg to Knoxville (MDT-TYS)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to Knoxville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to Knoxville

Tue, Jan 20 - Sat, Jan 24
United Airlines Logo
10:34 am - 2:49 pmMDT-TYS
4h 15m1 stop
United Airlines Logo
1:59 pm - 9:05 pmTYS-MDT
7h 06m1 stop
$229United Airlines
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Tue, Jan 20 - Tue, Jan 27
American Airlines Logo
3:08 pm - 10:54 pmMDT-TYS
7h 46m2 stops
American Airlines Logo
8:09 am - 12:13 pmTYS-MDT
4h 04m1 stop
$234American Airlines
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Tue, Jan 20 - Sat, Jan 24
American Airlines Logo
3:08 pm - 10:54 pmMDT-TYS
7h 46m2 stops
American Airlines Logo
3:00 pm - 10:27 pmTYS-MDT
7h 27m2 stops
$239American Airlines
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Wed, Dec 10 - Sun, Dec 14
Delta Logo
6:00 am - 11:47 amMDT-TYS
5h 47m1 stop
Delta Logo
5:40 am - 10:48 amTYS-MDT
5h 08m1 stop
$259Delta
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Fri, Dec 19 - Sat, Jan 10
American Airlines Logo
9:49 am - 3:47 pmMDT-TYS
5h 58m1 stop
American Airlines Logo
2:19 pm - 8:14 pmTYS-MDT
5h 55m1 stop
$264American Airlines
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Tue, Jan 13 - Tue, Jan 20
United Airlines Logo
10:34 am - 8:52 pmMDT-TYS
10h 18m2 stops
United Airlines Logo
11:10 am - 6:59 pmTYS-MDT
7h 49m2 stops
$269United Airlines
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Tue, Jan 20 - Sat, Jan 24
American Airlines Logo
3:08 pm - 8:56 pmMDT-TYS
5h 48m1 stop
American Airlines Logo
7:11 pm - 11:58 pmTYS-MDT
4h 47m1 stop
$289American Airlines
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Tue, Jan 20 - Sat, Jan 24
American Airlines Logo
3:08 pm - 10:54 pmMDT-TYS
7h 46m2 stops
American Airlines Logo
7:11 pm - 11:58 pmTYS-MDT
4h 47m1 stop
$294American Airlines
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Mon, Feb 2 - Wed, Feb 4
United Airlines Logo
3:10 pm - 8:52 pmMDT-TYS
5h 42m1 stop
United Airlines Logo
1:59 pm - 9:05 pmTYS-MDT
7h 06m1 stop
$297United Airlines
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Fri, Dec 5 - Sat, Dec 6
Delta Logo
7:27 pm - 11:28 pmMDT-TYS
4h 01m1 stop
Delta Logo
7:30 am - 11:56 amTYS-MDT
4h 26m1 stop
$299Delta
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Booking Insights

KAYAK's insights & trends for Harrisburg to Knoxville flights

Get data-powered insights and trends into flights from Harrisburg to Knoxville to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Harrisburg to Knoxville?

The average price of all round-trip flights from Harrisburg to Knoxville clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Knoxville on a Tuesday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Harrisburg to Knoxville. For your return ticket, we recommend flying on a Tuesday and avoiding Sundays for the best deals.

What is the cheapest month to fly from Harrisburg to Knoxville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Harrisburg to Knoxville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Harrisburg to Knoxville is May, where tickets cost $288 (return) on average. On the other hand, the most expensive months are September and June, where the average cost of round-trip tickets is $572 and $476 respectively.

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Good to know

Low seasonApril
Cheapest flight$140
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 43% increase in price.
Flight from Harrisburg to Knoxville

When to book flights from Harrisburg to Knoxville

Are your dates flexible? Find out the best times to travel from Harrisburg to Knoxville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Harrisburg to Knoxville

  • What is the cheapest flight from Harrisburg to Knoxville?

    In the last 3 days, the lowest price for a flight from Harrisburg to Knoxville was $140 for a one-way ticket and $229 for a round-trip.

  • Do I need a passport to fly between Harrisburg and Knoxville?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Harrisburg to Knoxville?

    Harrisburg and Knoxville are both served by 1 main airport. You will leave Harrisburg from Harrisburg and will be arriving at Knoxville McGhee Tyson.

  • Which aircraft models fly most regularly from Harrisburg to Knoxville?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Harrisburg to Knoxville?

    SkyTeam, and oneworld are the airline alliances operating flights between Harrisburg and Knoxville, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from Harrisburg to Knoxville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to Knoxville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to Knoxville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Knoxville from Harrisburg is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to Knoxville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Knoxville with an airline and back to Harrisburg with another airline. Booking your flights between Harrisburg and TYS can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to Knoxville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Knoxville from Harrisburg up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Harrisburg to Knoxville

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to Knoxville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to Knoxville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11038 reviews
8.0Crew
6.9Entertainment
7.5Boarding
7.2Comfort
6.4Food
Airline reviews

Delays to take off and to leave the plane after landing added a lot of time to this flight.

6.0 GoodMiguel, Oct 2025PHL - MIA
Read more American Airlines reviews

Delays to take off and to leave the plane after landing added a lot of time to this flight.

The Phildalphia to Allentown portion was a BUS, not a plane. All was as expected.

Excellent - explanations were clear staff was nice and flight was comfortable

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

Did not get the seat I selected and paid for.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

Flight was delayed and after being in the airport for like seven hours, it was canceled.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

Overall very good, only complaint I have is the crew from CLT to SAT could have collected trash sooner.

Everything you need to know for your flight from Harrisburg to Knoxville

Information on your arrival and departure airports

Harrisburg (MDT)
Knoxville (TYS)