MDT - PTY

$522 Find Cheap Flights from Harrisburg to Panama City

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to Panama City departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$522
United Airlines
Sun 2/22Thu 2/26
MDT - PTY • 2 stops
Cheapest one-way
Multiple Airlines
Sat 12/6
MDT - PTY • multi-stop
Top airlines
United Airlines
Cheapest • from $522 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Harrisburg to Panama City (MDT-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to Panama City

Sun, Feb 22 - Thu, Feb 26
United Airlines Logo
6:29 am - 8:02 pm
MDT
-
PTY
13h 33m2 stops
United Airlines Logo
4:41 pm - 9:06 pm
PTY
-
MDT
28h 25m2 stops
$522United Airlines
Thu, Mar 12 - Thu, Mar 19
United Airlines Logo
6:15 am - 6:38 pm
MDT
-
PTY
13h 23m2 stops
United Airlines Logo
9:30 am - 9:32 am
PTY
-
MDT
23h 02m2 stops
$529United Airlines
Tue, Mar 17 - Sat, Mar 28
United Airlines Logo
5:40 pm - 1:45 pm
MDT
-
PTY
21h 05m2 stops
United Airlines Logo
10:55 pm - 4:47 pm
PTY
-
MDT
16h 52m2 stops
$568United Airlines
Sun, May 17 - Fri, May 22
Delta Logo
6:00 am - 12:55 pm
MDT
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:41 pm
PTY
-
MDT
8h 21m1 stop
$628Delta
Tue, Mar 17 - Sat, Mar 28
United Airlines Logo
5:40 pm - 1:45 pm
MDT
-
PTY
21h 05m2 stops
United Airlines Logo
10:55 pm - 4:47 pm
PTY
-
MDT
16h 52m2 stops
$632United Airlines
Tue, Mar 17 - Sat, Mar 28
American Airlines Logo
4:30 pm - 2:22 pm
MDT
-
PTY
22h 52m2 stops
American Airlines Logo
1:44 pm - 10:52 pm
PTY
-
MDT
8h 08m1 stop
$643American Airlines
Thu, Mar 12 - Thu, Mar 19
Delta Logo
6:00 am - 12:55 pm
MDT
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:47 pm
PTY
-
MDT
8h 27m1 stop
$694Delta
Tue, Mar 17 - Sat, Mar 28
Delta Logo
6:00 am - 12:55 pm
MDT
-
PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:47 pm
PTY
-
MDT
8h 27m1 stop
$916Delta
Fri, Jan 23 - Wed, Feb 4
Delta Logo
6:00 am - 1:55 pm
MDT
-
PTY
7h 55m1 stop
Delta Logo
3:20 pm - 11:26 pm
PTY
-
MDT
8h 06m1 stop
$926Delta
Sun, May 17 - Fri, May 22
American Airlines Logo
7:59 pm - 12:15 pm
MDT
-
PTY
17h 16m3 stops
American Airlines Logo
1:50 pm - 9:09 am
PTY
-
MDT
18h 19m2 stops
$2,336American Airlines
Booking Insights

KAYAK's insights & trends for Harrisburg to Panama City flights

Get data-powered insights and trends into flights from Harrisburg to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Harrisburg to Panama City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Harrisburg to Panama City were found on United Airlines ($522) and Delta ($628).

Which airlines fly non-stop between Harrisburg and Panama City?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Harrisburg to Panama City.

There are 2 airlines that fly nonstop from Harrisburg to Panama City. They are American Airlines and Delta. The cheapest airline for this route is Delta, with the best round-trip deal found costing $491. On average, the best prices for this route can be found at American Airlines.

Good to know

Low seasonAugust
Cheapest flight$522
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Harrisburg to Panama City

When to book flights from Harrisburg to Panama City

Are your dates flexible? Find out the best times to travel from Harrisburg to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Harrisburg to Panama City

  • What is the cheapest flight from Harrisburg to Panama City?

    In the last 3 days, the lowest price for a flight from Harrisburg to Panama City was $522 for a round-trip ticket.

  • Do I need a passport to fly between Harrisburg and Panama City?

    Yes

  • Which aircraft models fly most regularly from Harrisburg to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Harrisburg to Panama City?

    SkyTeam, and oneworld are the airline alliances operating flights between Harrisburg and Panama City, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Harrisburg to Panama City, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Harrisburg to Panama City are Delta and American Airlines. With an average price for the route of $699 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $546 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from Harrisburg to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Harrisburg is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Harrisburg with another airline. Booking your flights between Harrisburg and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Harrisburg up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Harrisburg to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8009 reviews
8.1Boarding
8.5Crew
7.9Comfort
7.9Entertainment
7.3Food
Airline reviews

Left on time, a bit delayed due to headwinds most of the trip.

10.0 ExcellentCharles, Dec 2025
DTW - PHX
Read more Delta reviews

Left on time, a bit delayed due to headwinds most of the trip.

I fly Delta all the time, have Platinum Medallion status. But this route seems to have major problems with delays and seems to never leave on time! Have only taken it twice in the last two weeks, and each time it had delays of more than 1 hour... very disappointed!!!!

Getting to the flight was arduous and lengthy. The flight itself was good but the food option wasn’t a good selection. I need to do a Kosher option on my return. Flight crew were nice

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

Delays to take off and to leave the plane after landing added a lot of time to this flight.

The Phildalphia to Allentown portion was a BUS, not a plane. All was as expected.

Excellent - explanations were clear staff was nice and flight was comfortable

Airport in MXP is crazy. Get there at least 2 hours before flight.

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

Did not get the seat I selected and paid for.

The flight was canceled 3 hours after original take off time

Plane was delayed for 6 hours, at first by weather, which is understandable, but was further delayed with NO given reason for 2 1/2 hours more. We had no clue when we were going to depart actually until they opened the ramp. VERY POOR to ZERO COMMUNICATION!!!

Flight was delayed and after being in the airport for like seven hours, it was canceled.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

Everything you need to know for your flight from Harrisburg to Panama City

Information on your arrival and departure airports