Which airports can I use when flying from Harrisburg to Panama City?

Flights from Harrisburg to Panama City usually depart from Harrisburg (MDT) and arrive at Panama City Tocumen Intl (PTY).

What cabin classes can I book on flights from Harrisburg to Panama City?

Two cabin classes are available on flights from Harrisburg to Panama City: • Economy Class • First Class

Which airports do connecting flights from Harrisburg to Panama City pass through?

Most connecting flights from Harrisburg to Panama City pass through Atlanta Hartsfield-Jackson (ATL), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.

Can I save money by using flexible dates for flights from Harrisburg to Panama City?

Yes. Being flexible with your travel dates can save you up to 64% on the Harrisburg to Panama City route. Tuesday is the cheapest departure day at $617 round-trip on average, while Friday is the most expensive at $1,676, a difference of $1,059. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

What popular places can I visit in Panama City?

Some of the most popular sights in Panama City are Panama City Centre, Avenida Balboa and Multiplaza Pacific. These are among the most viewed places in Panama City on KAYAK.

How long is a flight from Harrisburg to Panama City?

A nonstop flight from Harrisburg to Panama City takes 0h 00m, covering 2,155 miles.

Do I need a passport to fly from Harrisburg to Panama City?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Harrisburg to Panama City changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $636 to $5,025. That means the highest observed fare was about 8x higher than the lowest one.

How are flight prices from Harrisburg to Panama City looking right now?

One-way fares from Harrisburg to Panama City are currently higher than usual. Average one-way flight prices are about $754, which is 131% above the typical average for this route.

What is the time difference between Harrisburg and Panama City?

Panama City is 1 hour behind Harrisburg (Eastern Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Panama City Tocumen Intl Airport (PTY)?

Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include: • Avis • Europcar • Ace • Budget • Hertz

How much should I expect to pay for a Harrisburg to Panama City flight?

Round-trip flights from Harrisburg to Panama City range from $628 to $953, with an average of $735 over the past 12 months. Anything below $628 counts as a good deal.

What is the cheapest airline to fly from Harrisburg to Panama City?

United Airlines ($636) and Copa Airlines ($714) are the cheapest airlines to fly round-trip from Harrisburg to Panama City according to KAYAK data over the last 5 days.

What is the cheapest layover airport when flying from Harrisburg to Panama City?

Flights via Atlanta Hartsfield-Jackson (ATL) offer the most affordable fares, with an average round-trip price of $708. Based on KAYAK data over the past 3 months.

When flying from Harrisburg to Panama City which airport offers the shortest layover?

Atlanta Hartsfield-Jackson (ATL) had the shortest average connection time for Harrisburg to Panama City layovers at 279 minutes over the past 3 months.

$310 CHEAP FLIGHTS from Harrisburg to Panama City (MDT - PTY)

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Cheapest round-trip

$636

Typical prices: $628-$953

United Airlines

Sun 10/28Sun 11/4

MDT - PTY • 2 stops

Cheapest one-way

$310

Typical prices: $291-$433

United Airlines

Tue 1/16

MDT - PTY • 2 stops

Nonstop flights

Not available

There are currently no direct flights between Harrisburg and Panama City. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

January

Cheapest • 16% price drop

April

Most popular

Good to know

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We hope you love your trip to Panama City!

Flight Deals

Cheap Flights from Harrisburg to Panama City (MDT-PTY)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Recent round-trip flight deals from Harrisburg to Panama City

Wed, Oct 28 - Wed, Nov 4

8:13 pm - 6:38 pmMDT Harrisburg-PTY Panama City Tocumen Intl

23h 25m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl

4:41 pm - 9:53 amPTY Panama City Tocumen Intl-MDT Harrisburg

17h 12m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$636United Airlines

Sat, Jan 16 - Thu, Jan 21

5:39 pm - 8:02 pmMDT Harrisburg-PTY Panama City Tocumen Intl

26h 23m2 stops Chicago O'Hare Intl Newark

8:55 am - 9:24 amPTY Panama City Tocumen Intl-MDT Harrisburg

24h 29m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$645United Airlines

Mon, Oct 26 - Mon, Nov 2

8:13 pm - 7:02 pmMDT Harrisburg-PTY Panama City Tocumen Intl

23h 49m2 stops Washington, D.C. Dulles Intl Newark

10:00 am - 1:24 pmPTY Panama City Tocumen Intl-MDT Harrisburg

27h 24m2 stops Newark Chicago O'Hare Intl

$656United Airlines

Sat, Jan 16 - Thu, Jan 21

5:39 pm - 5:12 pmMDT Harrisburg-PTY Panama City Tocumen Intl

23h 33m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

4:41 pm - 8:55 pmPTY Panama City Tocumen Intl-MDT Harrisburg

28h 14m1 stop Houston George Bush Intcntl

$714Copa Airlines

Sat, Jan 16 - Thu, Jan 21

2:30 pm - 8:02 pmMDT Harrisburg-PTY Panama City Tocumen Intl

29h 32m2 stops Washington, D.C. Dulles Intl Newark

4:41 pm - 8:55 pmPTY Panama City Tocumen Intl-MDT Harrisburg

28h 14m1 stop Houston George Bush Intcntl

$727Copa Airlines

Sat, Jan 16 - Thu, Jan 21

6:00 am - 1:55 pmMDT Harrisburg-PTY Panama City Tocumen Intl

7h 55m1 stop Atlanta Hartsfield-Jackson

3:20 pm - 11:38 pmPTY Panama City Tocumen Intl-MDT Harrisburg

8h 18m1 stop Atlanta Hartsfield-Jackson

$849Delta

Sat, Jan 16 - Thu, Jan 21

6:00 am - 3:00 pmMDT Harrisburg-PTY Panama City Tocumen Intl

33h 00m3 stops Washington, D.C. Dulles Intl Guatemala City La Aurora San José Juan Santamaria Intl

3:55 pm - 9:24 amPTY Panama City Tocumen Intl-MDT Harrisburg

17h 29m2 stops San Salvador El Salvador Intl Washington, D.C. Dulles Intl

$900Avianca

Wed, Oct 7 - Sat, Oct 10

5:54 pm - 7:31 pmMDT Harrisburg-PTY Panama City Tocumen Intl

26h 37m2 stops Chicago O'Hare Intl Newark

9:45 am - 9:51 amPTY Panama City Tocumen Intl-MDT Harrisburg

23h 06m2 stops Newark Chicago O'Hare Intl

$1,026Copa Airlines

Sat, Jan 16 - Thu, Jan 21

6:00 am - 1:36 pmMDT Harrisburg-PTY Panama City Tocumen Intl

7h 36m1 stop Miami

4:55 pm - 1:29 pmPTY Panama City Tocumen Intl-MDT Harrisburg

20h 34m2 stops Miami Chicago O'Hare Intl

$1,058American Airlines

Wed, Oct 7 - Sat, Oct 10

6:00 am - 12:59 pmMDT Harrisburg-PTY Panama City Tocumen Intl

7h 59m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:39 pmPTY Panama City Tocumen Intl-MDT Harrisburg

8h 15m1 stop Atlanta Hartsfield-Jackson

$1,188Delta

Booking Insights

Price, demand and travel trends for Harrisburg to Panama City flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Harrisburg to Panama City with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Harrisburg to Panama City?

Round-trip flights from Harrisburg to Panama City start at $636. Prices are typical for this route right now, with typical round-trip fares ranging from $628 to $953. The lowest price found in the past 5 days was $636 on United Airlines.

Find deals

Low season	July
High season	April
Cheapest flight	$310

Best time to beat the crowds but there is an average 45% increase in price.

Flight from Harrisburg to Panama City

When to book flights from Harrisburg to Panama City

Are your dates flexible? Find out the best times to travel from Harrisburg to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Harrisburg to Panama City?
Flights from Harrisburg to Panama City usually depart from Harrisburg (MDT) and arrive at Panama City Tocumen Intl (PTY).
What cabin classes can I book on flights from Harrisburg to Panama City?
Two cabin classes are available on flights from Harrisburg to Panama City:

• Economy Class
• First Class
Which airports do connecting flights from Harrisburg to Panama City pass through?
Most connecting flights from Harrisburg to Panama City pass through Atlanta Hartsfield-Jackson (ATL), which handles 100% of one-stop traffic on this route. Other layover airports each see under 5%.
Can I save money by using flexible dates for flights from Harrisburg to Panama City?
Yes. Being flexible with your travel dates can save you up to 64% on the Harrisburg to Panama City route. Tuesday is the cheapest departure day at $617 round-trip on average, while Friday is the most expensive at $1,676, a difference of $1,059. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
What popular places can I visit in Panama City?
Some of the most popular sights in Panama City are Panama City Centre, Avenida Balboa and Multiplaza Pacific. These are among the most viewed places in Panama City on KAYAK.
How long is a flight from Harrisburg to Panama City?
A nonstop flight from Harrisburg to Panama City takes 0h 00m, covering 2,155 miles.
Do I need a passport to fly from Harrisburg to Panama City?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
Have flight prices from Harrisburg to Panama City changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $636 to $5,025. That means the highest observed fare was about 8x higher than the lowest one.
How are flight prices from Harrisburg to Panama City looking right now?
One-way fares from Harrisburg to Panama City are currently higher than usual. Average one-way flight prices are about $754, which is 131% above the typical average for this route.
What is the time difference between Harrisburg and Panama City?
Panama City is 1 hour behind Harrisburg (Eastern Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Panama City Tocumen Intl Airport (PTY)?
Panama City Tocumen Intl Airport (PTY) hosts 5 major car rental companies, with daily rates starting from around $1 for economy cars. Top options include:
• Avis
• Europcar
• Ace
• Budget
• Hertz
How much should I expect to pay for a Harrisburg to Panama City flight?
Round-trip flights from Harrisburg to Panama City range from $628 to $953, with an average of $735 over the past 12 months. Anything below $628 counts as a good deal.

If your dates can be flexible, aim for a Tuesday departure instead of Friday. On this route, Tuesday flights average $617 - about $1,059 less than Friday (63% savings) based on the last 12 months.
If you can choose when to travel, plan your Harrisburg to Panama City trip for January. Fares historically average $617 round-trip in that month - typically $1,059 less than the most expensive month, which is August (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Panama City Tocumen Intl Airport.
- Riande Aeropuerto Hotel & Casino

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MDT - PTY

$310 Find Cheap Flights from Harrisburg to Panama City - Compare and Save

Everything you should know

Cheap Flights from Harrisburg to Panama City (MDT-PTY)

Recent round-trip flight deals from Harrisburg to Panama City

Recent one-way flight deals from Harrisburg to Panama City

Price, demand and travel trends for Harrisburg to Panama City flights

How much is a round-trip flight from Harrisburg to Panama City?

What is the cheapest airline to fly from Harrisburg to Panama City?

What is the cheapest layover airport when flying from Harrisburg to Panama City?

When flying from Harrisburg to Panama City which airport offers the shortest layover?

Key details for Harrisburg to Panama City flights

Low season

High season

Cheapest flight

When to book flights from Harrisburg to Panama City

Your Harrisburg to Panama City flight questions, answered

Your guide to booking Harrisburg to Panama City flights

More options for your flight from Harrisburg to Panama City

Complete your trip to Panama City with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Harrisburg to Panama City

Find direct flights to and from Harrisburg and Panama City

Flights from domestic origins to Panama City

Flights to other popular destinations