MDT - SDQ

$171 Find Cheap Flights from Harrisburg to Santo Domingo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Harrisburg to Santo Domingo departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santo Domingo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Santo Domingo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Harrisburg to Santo Domingo, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$369
American Airlines
Tue 4/28Tue 5/12
MDT - SDQ • 2 stops
Cheapest one-way
$171
American Airlines
Tue 5/26
MDT - SDQ • 1 stop
Top airlines
Cheapest • from $369 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Harrisburg and Santo Domingo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $589 (round-trip)
Shortest trip • 7h 05m (one-way)
Insights
Insights
Insights
Insights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santo Domingo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Harrisburg to Santo Domingo (MDT-SDQ)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Harrisburg to Santo Domingo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Harrisburg to Santo Domingo

Tue, Apr 28 - Tue, May 12
American Airlines Logo
7:51 pm - 2:59 pm
MDT
-
SDQ
19h 08m
2 stops
American Airlines Logo
4:00 pm - 10:57 am
SDQ
-
MDT
18h 57m
2 stops
$369American Airlines
Sun, Apr 12 - Thu, Apr 23
Multiple Airlines Logo
10:06 pm - 10:07 am
MDT
-
SDQ
12h 01m
1 stop
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$388Multiple Airlines
Thu, Apr 9 - Thu, Apr 23
Multiple Airlines Logo
9:11 pm - 10:07 am
MDT
-
SDQ
12h 56m
1 stop
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$392Multiple Airlines
Sat, Apr 11 - Thu, Apr 23
Multiple Airlines Logo
6:23 pm - 10:15 pm
MDT
-
SDQ
27h 52m
2 stops
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$403Multiple Airlines
Mon, Apr 13 - Thu, Apr 23
Multiple Airlines Logo
6:16 pm - 1:15 pm
MDT
-
SDQ
18h 59m
1 stop
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$410Multiple Airlines
Fri, Apr 10 - Fri, Apr 17
American Airlines Logo
4:59 pm - 9:20 am
MDT
-
SDQ
16h 21m
2 stops
American Airlines Logo
6:00 am - 12:31 am
SDQ
-
MDT
18h 31m
2 stops
$419American Airlines
Sun, Mar 29 - Mon, Mar 30
Multiple Airlines Logo
10:13 pm - 9:41 am
MDT
-
SDQ
11h 28m
1 stop
Multiple Airlines Logo
2:52 am - 5:58 pm
SDQ
-
MDT
15h 06m
2 stops
$424Multiple Airlines
Thu, Apr 9 - Thu, Apr 16
Multiple Airlines Logo
9:11 pm - 10:07 am
MDT
-
SDQ
12h 56m
1 stop
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$425Multiple Airlines
Mon, Apr 13 - Thu, Apr 23
Multiple Airlines Logo
10:58 pm - 1:15 pm
MDT
-
SDQ
14h 17m
2 stops
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$426Multiple Airlines
Fri, Apr 10 - Thu, Apr 23
Multiple Airlines Logo
10:06 pm - 1:15 pm
MDT
-
SDQ
15h 09m
2 stops
Multiple Airlines Logo
2:35 pm - 5:26 pm
SDQ
-
MDT
26h 51m
1 stop
$431Multiple Airlines
Booking Insights

KAYAK's insights & trends for Harrisburg to Santo Domingo flights

Get data-powered insights and trends into flights from Harrisburg to Santo Domingo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Harrisburg to Santo Domingo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Harrisburg to Santo Domingo were found on American Airlines ($369) and Delta ($451).

Good to know

Low seasonOctober
Cheapest flight$171
Best time to beat the crowds with an average 28% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Harrisburg to Santo Domingo

When to book flights from Harrisburg to Santo Domingo

Are your dates flexible? Find out the best times to travel from Harrisburg to Santo Domingo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Harrisburg to Santo Domingo

  • What is the cheapest flight from Harrisburg to Santo Domingo?

    In the last 3 days, the lowest price for a flight from Harrisburg to Santo Domingo was $171 for a one-way ticket and $369 for a round-trip.

  • Do I need a passport to fly between Harrisburg and Santo Domingo?

    A passport is required to fly from Harrisburg to Santo Domingo.

  • Which airports will I be using when flying from Harrisburg to Santo Domingo?

    On your way to Santo Domingo, you’ll fly out from Harrisburg. You’ll be landing at Santo Domingo Las Americas.

  • Which aircraft models fly most regularly from Harrisburg to Santo Domingo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Harrisburg to Santo Domingo?

    SkyTeam, and oneworld are the airline alliances operating flights between Harrisburg and Santo Domingo, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Harrisburg to Santo Domingo, Delta or American Airlines?

    The two airlines most popular with KAYAK users for flights from Harrisburg to Santo Domingo are Delta and American Airlines. With an average price for the route of $597 and an overall rating of 7.9, Delta is the most popular choice. American Airlines is also a great choice for the route, with an average price of $602 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from Harrisburg to Santo Domingo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Harrisburg to Santo Domingo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Harrisburg to Santo Domingo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santo Domingo from Harrisburg is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Harrisburg to Santo Domingo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santo Domingo with an airline and back to Harrisburg with another airline. Booking your flights between Harrisburg and SDQ can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Harrisburg to Santo Domingo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santo Domingo from Harrisburg up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Harrisburg to Santo Domingo

 
See real verified KAYAK customer reviews for airlines flying from Harrisburg to Santo Domingo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Harrisburg to Santo Domingo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8286 reviews
8.1Boarding
7.9Comfort
7.8Entertainment
7.2Food
8.5Crew
Airline reviews

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

10.0 ExcellentDebra, Mar 2026
PBI - ATL
Read more Delta reviews

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

We landed and sat on the tarmac for 45 minutes because they only have one gate at the airport and there was another plane running late so we had to wait

The WiFi was not working. That made for a long flight.

With Aeromexico it ended up good but with Delta it was bad because we did everything through Delta... Showed up at the Delta terminal... It was the wrong place! Nothing ever told us to go to the Aeromexico terminal. It said "in partnership with Aeromexico" but I was never instructed to check in with them or go to their terminal. We had to haul @$$ running through the airport and almost didn't make it thanks to this poor communication. 👎🏽

Absolutely no communication on why there's a delay and multiple flight time reschedules. I would have canceled the flight and drove back home if I known it was going to be rescheduled 3 or 4 times.

Another late night flight and MORE men belligerently drinking and yelling. I had to move from first to economy because they were so obnoxious and disruptive. Crazy to go from a cozy chair to cardboard when you were supposed to be in first. Delta allows was too much drinking which leads to belligerent behavior.

I was in first class and literally the men behind me were so aggressively loud I moved myself to economy. This has become so common on Delta - people using audio without headphones, and men on 12am / late night flights drinking and yelling to talk to each other which prevents anyone around them from resting. Pretty crazy to have to move from first to economy (poorer service, less comfort...). Wild wild. Looking into other airlines.

Love delta smaller commuter plane so no entertainment and paid wifi on MKE-LGA leg was extremely unreliable and slow

It would have been nice if American tried to care.

Delayed initially because they couldn’t print the flight details. Poor instruction on delay. When I got on the plane the flight attendant argued with me about whether my carry on would fit (it did, although she didn’t acknowledge that). No greeting (other than arguing with me) getting on or off the plane.

Beverage service was not good. Also just one service in 5 hr 30 min flight. No ask fir water ir anything beside one time beverage service.

They are always late and seats was also not having working charger

Broke my luggage and I can't get a resolution yet.

My flight to London from Philadelphia was cancelled due to weather.

Pilot navigated severe weather/snow storm with skill. Described his intentions clearly

This flight captain and crew were amazing, started ahead of time of departure and reached 30 mins before arrival time. Amazing!

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

Everything you need to know for your flight from Harrisburg to Santo Domingo

Information on your arrival and departure airports