$160 Find Cheap Flights from Houston to Panama

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Houston to Panama departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Houston to Panama

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Panama City
Panama City2 stops$433
Bocas del Toro
Bocas del Toro2 stops$997
Panama City
Panama City2 stops$433
Bocas del Toro
Bocas del Toro2 stops$997

Book Cheap Houston to Panama Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Houston to Panama that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Houston to Panama

Wed, Mar 4 - Mon, Mar 9
Multiple Airlines Logo
3:37 pm - 8:50 am
IAH
-
PTY
16h 13m
2 stops
Multiple Airlines Logo
9:45 am - 12:24 pm
PTY
-
IAH
26h 39m
2 stops
$434Multiple Airlines
Tue, Feb 24 - Tue, Mar 3
Multiple Airlines Logo
6:30 am - 2:00 pm
IAH
-
PTY
30h 30m
3 stops
Multiple Airlines Logo
5:50 pm - 12:18 am
PTY
-
IAH
31h 28m
3 stops
$456Multiple Airlines
Tue, Apr 21 - Sat, Apr 25
Multiple Airlines Logo
6:00 am - 9:15 am
IAH
-
PTY
27h 15m
3 stops
Multiple Airlines Logo
9:55 am - 11:51 pm
PTY
-
IAH
13h 56m
2 stops
$457Multiple Airlines
Wed, Mar 4 - Mon, Mar 9
Multiple Airlines Logo
12:16 pm - 8:50 am
IAH
-
PTY
19h 34m
3 stops
Multiple Airlines Logo
9:45 am - 12:24 pm
PTY
-
IAH
26h 39m
2 stops
$462Multiple Airlines
Tue, Feb 24 - Tue, Mar 3
Delta Logo
5:25 am - 1:50 pm
HOU
-
PTY
7h 25m
1 stop
Delta Logo
3:15 pm - 10:28 pm
PTY
-
HOU
8h 13m
1 stop
$775Delta
Tue, Mar 10 - Wed, Mar 18
American Airlines Logo
4:20 pm - 12:40 pm
HOU
-
PTY
20h 20m
2 stops
American Airlines Logo
3:10 pm - 9:43 am
PTY
-
HOU
18h 33m
2 stops
$779American Airlines
Mon, Apr 20 - Mon, Apr 27
Delta Logo
6:00 am - 1:02 pm
HOU
-
PTY
7h 02m
1 stop
Delta Logo
2:27 pm - 9:51 am
PTY
-
HOU
19h 24m
1 stop
$787Delta
Mon, May 4 - Mon, May 11
JetBlue Logo
6:00 am - 1:02 pm
HOU
-
PTY
7h 02m
1 stop
JetBlue Logo
2:20 pm - 9:20 am
PTY
-
HOU
19h 00m
1 stop
$866JetBlue
Thu, Apr 2 - Sun, Apr 12
American Airlines Logo
8:20 pm - 3:01 pm
HOU
-
PTY
18h 41m
2 stops
American Airlines Logo
1:49 pm - 12:12 pm
PTY
-
HOU
22h 23m
2 stops
$879American Airlines
Tue, Jun 2 - Tue, Jun 30
LATAM Airlines Logo
6:00 am - 12:55 pm
HOU
-
PTY
6h 55m
1 stop
LATAM Airlines Logo
2:20 pm - 9:20 am
PTY
-
HOU
19h 00m
1 stop
$912LATAM Airlines
Booking Insights

KAYAK's insights & trends for Houston to Panama flights

Get data-powered insights and trends into flights from Houston to Panama to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Houston to Panama flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Panama from Houston found in the last 72 hours was to Panama City, at $506 round-trip. The most popular route is from Houston George Bush Intcntl Airport (IAH) to Panama City (PTY), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $506.

What is the cheapest month to fly from Houston to Panama?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Houston to Panama, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Houston to Panama is January, when tickets cost $788 (return) on average. On the other hand, the most expensive months are April and December, when the average cost of round-trip tickets is $1,028 and $1,001 respectively.

What’s the cheapest day of the week to fly from Houston to Panama?

The average price of all round-trip flights from Houston to Panama clicked on KAYAK for each day over the last 12 months.

For Houston to Panama, Tuesday is the cheapest day to fly on average and Sunday is the most expensive. Flying from Panama back to Houston, the best deals are generally found on Tuesday, with Sunday being the most expensive.

How far in advance should I book a flight from Houston to Panama?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Houston to Panama, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Houston to Panama, you should book around 5 weeks before departure, which saves you about 28% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Good to know

Cheapest flight$160
Flight from Houston George Bush Airport to Panama City

FAQs - booking Panama flights

  • How does KAYAK find such low prices on flights from Houston to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Houston to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Houston to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Houston to Panama is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Houston to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Houston to Panama with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Houston to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Houston to Panama up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Panama?

    The cheapest time of day to fly to Panama is generally in the afternoon, when round-trip flights cost $885 on average. The most expensive time of day to fly to Panama is generally in the morning, which is peak travel time and where the average cost of a ticket is $904.

Reviews of the top airlines flying from Houston to Panama

 
Need help choosing which airline to fly with from Houston to Panama? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1560 reviews
7.4Comfort
8.1Crew
6.8Food
7.8Boarding
6.8Entertainment
Airline reviews

Seats were awful. Media should have been included for such a long flight.

4.0 OkayPaul, Jan 2026
LIM - PTY
Read more Copa Airlines reviews

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

Cops Airlines is fantastic! The level of care and professionalism provided by the entire crew was top rate.

the food served was an embarrassment. No connection for charging the cellphone... What a crappy airline.

I like flying first class, and United has a nice one

Unbelievably poor service from flight attendants. They didn’t even do water service on a four hour flight. Just disrespectful.

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Crew was excellent. This was a relatively long flight though and had very little leg room, and no entertainment.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

Plane was crowded and even when we hit altitude, the plane was hot, not enough air flow.

Flight was delayed and missed my connection Lufthansa didn’t respond.

the delay for 3 hours was understandable due to weather conditions but the flight should’ve provided some on flight compensations or at least provide more food.

United could have one single once of customer service. No human United employee would help me with the invalid mileage plus number, they said I had to speak with the computer.

Everything you need to know for your flight from Houston to Panama

Cabin class types available on flights to Panama

Cabin classes available on flights to Panama. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.