OAJ - DSM

$377 Find Cheap Flights from Jacksonville to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Jacksonville to Des Moines departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Jacksonville to Des Moines, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Jacksonville to Des Moines, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$377
Delta
Sat 2/7Wed 2/11
OAJ - DSM • 1 stop
Cheapest one-way
$264
Delta
Tue 12/16
OAJ - DSM • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Jacksonville to Des Moines (OAJ-DSM)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Jacksonville to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Jacksonville to Des Moines

Sat, Feb 7 - Wed, Feb 11
Delta Logo
5:40 am - 12:15 pmOAJ-DSM
7h 35m1 stop
Delta Logo
5:35 am - 11:04 amDSM-OAJ
4h 29m1 stop
$377Delta
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Sat, Feb 7 - Wed, Feb 11
Delta Logo
11:49 am - 9:24 pmOAJ-DSM
10h 35m2 stops
Delta Logo
5:35 am - 11:04 amDSM-OAJ
4h 29m1 stop
$382Delta
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Thu, Feb 19 - Sun, Feb 22
Delta Logo
6:40 pm - 10:28 pmOAJ-DSM
4h 48m1 stop
Delta Logo
5:15 pm - 10:35 pmDSM-OAJ
4h 20m1 stop
$400Delta
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Thu, Feb 19 - Sun, Feb 22
Delta Logo
2:15 pm - 9:17 pmOAJ-DSM
8h 02m2 stops
Delta Logo
5:15 pm - 10:35 pmDSM-OAJ
4h 20m1 stop
$405Delta
Find Deal
Sat, Feb 7 - Wed, Feb 11
Delta Logo
11:49 am - 9:24 pmOAJ-DSM
10h 35m2 stops
Delta Logo
7:34 am - 9:42 pmDSM-OAJ
13h 08m2 stops
$429Delta
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Thu, Feb 19 - Sun, Feb 22
American Airlines Logo
5:00 am - 1:09 pmOAJ-DSM
9h 09m2 stops
American Airlines Logo
7:45 pm - 12:38 pmDSM-OAJ
15h 53m2 stops
$498American Airlines
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Booking Insights

KAYAK's insights & trends for Jacksonville to Des Moines flights

Get data-powered insights and trends into flights from Jacksonville to Des Moines to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Jacksonville and Des Moines?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Jacksonville to Des Moines.

There is just one airline that flies from Jacksonville to Des Moines direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $296.

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Good to know

Cheapest flight$264
Flight from Jacksonville to Des Moines

When to book flights from Jacksonville to Des Moines

Are your dates flexible? Find out the best times to travel from Jacksonville to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Jacksonville to Des Moines

  • What is the cheapest flight from Jacksonville to Des Moines?

    In the last 3 days, the lowest price for a flight from Jacksonville to Des Moines was $264 for a one-way ticket and $377 for a round-trip.

  • Do I need a passport to fly between Jacksonville and Des Moines?

    A passport is not required to fly from Jacksonville to Des Moines.

  • Which aircraft models fly most regularly from Jacksonville to Des Moines?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Jacksonville to Des Moines?

    oneworld is the only airline alliance operating flights between Jacksonville and Des Moines.

  • How does KAYAK find such low prices on flights from Jacksonville to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Jacksonville to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Jacksonville to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines from Jacksonville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Jacksonville to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back to Jacksonville with another airline. Booking your flights between Jacksonville and DSM can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Jacksonville to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines from Jacksonville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Jacksonville to Des Moines

 
See real verified KAYAK customer reviews for airlines flying from Jacksonville to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Jacksonville to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11041 reviews
6.9Entertainment
6.5Food
8.0Crew
7.2Comfort
7.5Boarding
Airline reviews

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

8.0 ExcellentShirley, Nov 2025ILM - CLT
Read more American Airlines reviews

I had a positive experience on American. I'm blind and traveling with a guide dog and the flight attendants were so kind, friendly, and helpful towards us. They checked in on us during the flight and they made us feel comfortable and welcomed. There was an hour delay before depature, but overall the flight was a smooth ride. I appreciate that there were no issues on this long flight back home.

Flight delayed and missed connection. Rescheduled flight cancelled after 6 hrs wait. Rerouted thru ORD, flight cancelled, overnight stay in ORD. Still in the air on new flight!

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

You can plug your phone in & use their wifi to watch movies, etc, but the plane’s wifi was disconnected for most of the flight.

Very below average , plane from Dallas to Toyko was very poor designed plane. I had to sit for 13 hours next to fat man. Really bad seat and entertainment screen sucked

Sat on the ground in Cincinnati for 50 minutes before deplaning

Flight was delayed. Staff at the gate effectively and proactively communicated about the delay.

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

This flight never occurred because AA couldn’t get their act together.

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Everything you need to know for your flight from Jacksonville to Des Moines

Information on your arrival and departure airports

Jacksonville (OAJ)
Des Moines (DSM)