DSM

$44 Find Cheap Flights to Des Moines

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Des Moines departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Des Moines

 
These are the airlines KAYAK users have selected most often from within our search results for flights to Des Moines
These are the airlines KAYAK users have selected most often from within our search results for flights to Des Moines
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$83
Typical prices: $332-$92
Allegiant Air
Fri 6/26Mon 6/29
HOU - DSM • Non-stop
Cheapest one-way
$44
Typical prices: $128-$396
Frontier
Wed 5/27
DEN - DSM • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
American's Main Cabin Extra offers early boarding.
Allegiant's Bonus bundle includes carry-on and seat choice.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Most flights • 264 per week
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top routes
Cheapest
Most popular
Insights
Insights
Insights
Insights
When to travel
Cheapest • 29% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Des Moines!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights to Des Moines

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights to Des Moines that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals to Des Moines

Fri, Jun 26 - Mon, Jun 29
Allegiant Air Logo
9:10 am - 11:22 am
HOU
-
DSM
2h 12mnonstop
Allegiant Air Logo
6:00 am - 8:20 am
DSM
-
HOU
2h 20mnonstop
$83Allegiant Air
Fri, Jul 10 - Mon, Jul 13
Allegiant Air Logo
4:52 pm - 7:04 pm
HOU
-
DSM
2h 12mnonstop
Allegiant Air Logo
1:37 pm - 4:02 pm
DSM
-
HOU
2h 25mnonstop
$94Allegiant Air
Wed, Jun 3 - Fri, Jun 5
Frontier Logo
10:44 am - 1:31 pm
DEN
-
DSM
1h 47mnonstop
Frontier Logo
2:16 pm - 3:18 pm
DSM
-
DEN
2h 02mnonstop
$121Frontier
Wed, Jun 3 - Fri, Jun 5
Frontier Logo
10:44 am - 1:31 pm
DEN
-
DSM
1h 47mnonstop
Frontier Logo
2:16 pm - 3:18 pm
DSM
-
DEN
2h 02mnonstop
$122Frontier
Wed, May 20 - Wed, May 27
American Airlines Logo
2:59 pm - 4:31 pm
ORD
-
DSM
1h 32mnonstop
American Airlines Logo
5:00 am - 6:43 am
DSM
-
ORD
1h 43mnonstop
$237American Airlines
Thu, Jun 4 - Wed, Jun 10
American Airlines Logo
7:00 am - 8:32 am
ORD
-
DSM
1h 32mnonstop
American Airlines Logo
7:13 pm - 9:10 pm
DSM
-
ORD
1h 57mnonstop
$253American Airlines
Wed, May 20 - Wed, May 27
Delta Logo
6:24 am - 10:16 am
ORD
-
DSM
3h 52m
1 stop
Delta Logo
1:04 pm - 4:51 pm
DSM
-
ORD
3h 47m
1 stop
$257Delta
Thu, Jun 4 - Wed, Jun 10
Delta Logo
6:24 am - 12:24 pm
ORD
-
DSM
6h 00m
1 stop
Delta Logo
6:08 am - 1:04 pm
DSM
-
ORD
6h 56m
1 stop
$273Delta
Wed, Jun 17 - Sat, Jun 20
Southwest Logo
6:00 am - 11:30 am
DCA
-
DSM
6h 30m
1 stop
Southwest Logo
5:10 am - 11:00 am
DSM
-
DCA
4h 50m
1 stop
$382Southwest
Sat, May 30 - Mon, Jun 1
Southwest Logo
6:40 am - 11:30 am
DCA
-
DSM
5h 50m
1 stop
Southwest Logo
4:20 pm - 10:55 pm
DSM
-
DCA
5h 35m
1 stop
$390Southwest
Booking Insights

KAYAK's insights & trends for flights to Des Moines

Get data-powered insights and trends for flights to Des Moines to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest flight to Des Moines?

These are the best round-trip prices found by users searching on KAYAK in the last 72 hours.

In the last 3 days, the cheapest flight deal to Des Moines was found on the route from Denver, at $83 return. The most popular connection is from Washington, D.C. to Des Moines and KAYAK users have found round-trip deals for as low as $367 in the last 3 days.

How much is a flight to Des Moines?

The average and cheapest price for all round-trip flights to Des Moines from each origin found by users searching on KAYAK in the last month.

A flight to Des Moines costs $298 on average. The cheapest price found on KAYAK in the last 2 weeks cost $43 and departed from Philadelphia. The most popular routes on KAYAK are Denver to Des Moines which costs $358 on average, and Chicago to Des Moines, which costs $458 on average.

See prices from:

What is the cheapest day to fly to Des Moines?

The average price of all round-trip flights to Des Moines clicked on KAYAK for each day over the last 12 months.

Based on KAYAK data, the cheapest day to fly to Des Moines is Thursday where round-trip tickets can be as cheap as $277. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $416 on average.

What is the cheapest month to fly to Des Moines?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights to Des Moines, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights to Des Moines is September, where tickets cost $289 on average for return flights. On the other hand, the most expensive months are January and March, where the average cost of tickets from the United States is $607 and $531 respectively. For one-way flights, the best month to travel is August with an average price of $339.

What is the cheapest time of day to fly to Des Moines?

The average price for all round-trip flights to Des Moines depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Des Moines is generally in the morning, when round-trip flights cost $295 on average. The most expensive time of day to fly to Des Moines is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $472.

What is a good deal for flights to Des Moines?

If you’re looking for cheap airfare to Des Moines, 25% of our users found tickets to Des Moines for the following prices or less: From Fort Lauderdale $145 round-trip, from John Wayne (Santa Ana) $157 round-trip, from Philadelphia $207 round-trip.

Expert advice

Expert advice for your flight to Des Moines

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Harriet Baskas

Harriet Baskas

Expert on American Airlines and Alaska Airlines

Harriet is an award-winning journalist who is happiest in an airport or an unusual museum. Her stories about airports, air travel, and the business of travel have appeared on NBC News, CNBC, USA TODAY, The Points Guy and other outlets. She is the creator of the StuckatTheAirport.com blog and the author of nine books. When not out on the road or exploring the latest airport amenities, she’s home in Seattle getting ready for the next adventure.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines, Delta and Frontier

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Daniel Scheffler

Daniel Scheffler

Expert on Allegiant Air

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Good to know - Book Cheap Des Moines Plane Tickets

Low seasonJanuary
Cheapest flight$44
Best time to beat the crowds but there is an average 22% increase in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Denver to Des Moines

When to book flights to Des Moines

Are your dates flexible? Find out the best times to travel to Des Moines based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. The information is for flights to Des Moines based on your location. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs - booking Des Moines flights

  • How to get from Des Moines International Airport to Des Moines city center?

    There are various ways to get from Des Moines International Airport to the city center after your flight to Des Moines: buses run daily from one place to the other, connecting the airport to the city for the convenience of all travelers, and a number of hotels in the area offer free shuttle services. Moreover, car rental desks and taxi ranks are conveniently located at the Arrivals Terminal for those who prefer to travel independently.

  • What kind of services does Des Moines International Airport offer?

    In order to stay at the top of its game and satisfy all travelers, Des Moines International Airport offers a range of services such as free Wi-Fi, ATM machines, mobile charging stations, massage chairs, a notary service, and cots to sleep on in the event of flight cancellations due to strikes or bad weather.

  • What attractions is Des Moines International Airport close to?

    Des Moines International Airport is indeed very close to Des Moines city center, but that is not all: the airport is also ideally located to visit attractions such as the Blank Park Zoo (2.3 miles to the east), the Willow Creek Golf Course (4.1 miles to the west), and the breathtaking Walnut Woods State Park (7.2 miles to the west), on the beautiful Raccoon River.

  • Are there malls near Des Moines International Airport?

    Yes, there are. If you are stuck on a long stopover and have exhausted all shopping options inside the airport, head out to one of the malls located not far from the Des Moines International Airport: the Southridge Mall and the Southgate Shopping Centre are the closest (3.2 and 4.1 miles to the east respectively), but there is also Shops at Roosevelt (6.3 miles to the north) and the Valley West Mall (8.8 miles to the northwest).

  • What domestic destinations can I connect to from Des Moines International Airport?

    There are ten popular domestic destinations from DSM that you can connect to from the airport. DSM to Denver is the busiest route served by Frontier, Southwest, and United Airlines. Delta Airlines offers flights to Atlanta, Minneapolis, and Detroit, while Southwest Airlines serves routes from DSM to Las Vegas and St. Louis. American Airlines offers flights to Chicago, Dallas, Phoenix, and Charlotte.

  • Does Des Moines International Airport offer accessibility services?

    DSM is fully accessible to passengers with special needs. The airport has ramps, lifts, accessible washrooms, and TDD phones in the main terminal area and the concourses. If you have reduced mobility, you can request a wheelchair with your airline. The airlines and airport offer special assistance services to passengers needing assistance around the airport. DSM also provides accessible transport services to and from the airport by prior arrangements.

  • Are there on-site car rental agencies at Des Moines International Airport?

    DSM's on-site car rental agencies include Alamo, Avis, Enterprise, Budget, National, Hertz, and American Rent-A-Car, with counters in the baggage claim area. The pick-up and drop-off location is adjacent to the South Garage car park. The minimum age for renting a car at DSM is 21 years. You must present a driver's license valid for the whole rental period. The airport does not allow digital licenses.

  • Is there a hotel in Des Moines International Airport?

    Although DSM doesn't have a hotel within the airport, there are three hotels across the street from the airport that you can visit upon landing. All these hotels are about a 2-minute drive. The hotels have free 24-hour shuttle services for transit from the airport's parking lot.

  • What is the cheapest flight to Des Moines?

    In the last 3 days, the cheapest flight deal to Des Moines was found on the route from Denver, at $83 return. The most popular connection is from Washington, D.C. to Des Moines and KAYAK users have found round-trip deals for as low as $367 in the last 3 days.

  • How far is Des Moines Airport from central Des Moines?

    You’ll need to travel 4 miles to reach the Des Moines city center from Des Moines Airport.

  • What is the name of Des Moines’s airport?

    All flights to Des Moines land at Des Moines Airport. The airport code is DSM,and it can also be referred to as Des Moines or Des Moines Intl.

  • How much is a flight to Des Moines?

    On average, a flight to Des Moines costs $298. The cheapest price found on KAYAK in the last 2 weeks cost $43 and departed from Philadelphia Airport.

  • How does KAYAK find such low prices on flights to Des Moines?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights to Des Moines.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket to Des Moines?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights to Des Moines?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Des Moines with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight to Des Moines?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Des Moines

  • Looking for cheap airfare to Des Moines? 25% of our users found round-trip tickets to Des Moines for the following prices or less: From Newark $164, from Phoenix Sky Harbor Intl $312, from Chicago O'Hare Intl $342
  • Enter your preferred departure airport and travel dates into the search form above to unlock the latest Des Moines flight deals.
  • Although smaller than other airports in the country, Des Moines International Airport still features a number of stores in which to do some last minute shopping while you are waiting for your flight. Head to the Capitol News & Gift shop in the lobby for souvenirs, newspapers, snacks, and University of Iowa apparel.
  • Eating at Des Moines International Airport is also not a problem as the Food Court, located on the first floors, offers a plethora of choices that will satisfy even the pickiest of eaters. Moreover, there is also a number of restaurants if you prefer a proper, sit-down meal.
  • If you have emails to write or want to conduct some business while waiting for your flight, head to the Business Center. It is fully equipped with workstations, internet access, and fax and photocopy services.
  • Perhaps your flight to Des Moines has arrived late and you don’t want to travel into the city, or your connecting flight doesn’t leave until the morning and you don’t fancy the idea of sleeping in the airport. Whatever the reason, if you want to spend the night in a comfortable bed, book a room at one of the hotels located just minutes from the airport, many of which offer free shuttle services as well as day rooms.
  • Traveling with a pet? Des Moines International Airport features a Pet Relief Area where your furry friends can do their business and rest a moment before or after your flight. It is located outside the terminal, not far from the parking garage.
  • Des Moines International Airport (DSM) is the main airport serving Des Moines. DSM also serves nearby cities without airports, including West Des Moines, Urbandale, Clive, and Johnston.
  • Upon arrival at DSM from long flights, go to the airside, on the second floor of the main terminal, and take advantage of the on-site massage chairs available in each concourse to relieve tension in your back.

Reviews of the top 5 airlines flying to Des Moines

 
See real verified KAYAK customer reviews for airlines flying to Des Moines. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline from the United States to Des Moines. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with to Des Moines? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4314 reviews
7.5Entertainment
8.0Comfort
7.0Food
8.6Crew
8.1Boarding
Airline reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

10.0 Excellentlarry, Apr 2026
LGB - PHX
Read more Southwest reviews

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

no service at all due to turbulence. they should've at least given us snacks, there were only 10 people on the entire flight.

First time I've had to use the disabled accommodations. And I could not have had a better experience with Southwest, i was having trouble getting from one terminal to another due to my heart failure. And the next thing I know a Southwest agent had made sure. I had a wheelchair at all my flights. Can't thank them enough.

Delayed flight, lack of information, boarding process is a mess as is the carryon luggage causing issues when leaving the plane….just a poor experience.

Comfortable. Easy. No problems. Just wish they had gf options for snacks.

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

This leg was much better, but we did have to have a 3 hour lay o er after coming from a very exhausting hiccup with our flight from BNA to Den

We waited in the airplane for over 45 min for a southwest employee to make the flight. This cause over half the plane to miss their connecting flight in Denver. When we confronted the desk upon arrival, they told us the only flight they had was the next day leaving at 8:50 pm!!! Or they offered to get us to Burbank or LA, but after that we were on our own to get back to Santa Barbara. I paid for a flight from sba to bna bna to sba. My re entry into mom mode has been 💯 rough because of southwest mistake with my flight. And now I’m leaving to Reno tomorrow for a vballl tournament and just discovered that my leg in Vegas has me and my 3 kids on a stand by flight even though I had booked these ticket last year November!! Do better southwest!

Southwest is kind of a slum airline. It’s gotten more expensive over the years for less and less service. I am a Southwest Chase Visa card holder and was forced to choose a seat in the 26th row in the middle seat. However my wife who is a rewards member but doesn’t hold a card or anything else, gets randomly assigned a normally paid seat in row 6! How does that work?

For the first time in a long time, the Wi-Fi actually worked the entire flight! The flight crew was amazing as usual.

The agent at check in and at the gate were less than thrilled to be at work. I'm not a fan of Kayak's placement on the plane. I got put in the middle seat and none of my preferences were used.

In ATL they have two sets of departure screens. Follow what is on your airline's departure board - the ATL Airport Authority departure board had completely incorrect details about the gate assignment for my flight, which would have made me miss boarding.

Flight was delayed it was hot while sitting on the plane, one engine was working on the plane until they had to do some jimmy rigging down the runway in order for the other engine to charge up. It was ridiculous

The flight was very good and the staff was very friendly and helpful!

The only thing I would say is we tried to get on a standby earlier flight, but with our fair we couldn’t. That seems senseless to leave with open seats..

Very easy to use and convenient, you can perform any action within the same portal

In a world of delays, Delta was on time both ways! Boarding was fast and efficient. Staff was friendly. AND wifi worked.

WiFi didn’t work. Flight delayed 3 hours Crew members were illiterate Seat lean back did not work.

Flight was delayed, we could have been notified earlier and in a consistent manner. App was not refreshing for another passenger to get the latest flight status. We could have stayed and waited at the hotel instead of waiting at the airport had we known the flight was going to delayed for more than 5 hours. The toilet is too tight, and needs to be cleaned more frequently (every hour). The entertainment screen froze, the touch screen not responding to touch. We were upgraded to comfort, it is more comfortable than regular economy seats.

This wasn't my experience with Delta. It was just the Pegasus flight. Seats were very hard. Staff was kinda rough. Not very nice. Charged me for snacks. For a 4 hour flight I would've expected more.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

A long delay. Don't travel late in the day.

Super friendly with lots of drink options an entertainment. Friendly crew.

Standard flight with a drinks and a snack- overall very quick flight. The flight attendants were very strict, bordered on rude.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

Delayed - weather wasn't bad at either end. Also sat on tarmac in ORD.

They told us yesterday APR21st that they were cleaning the plane and we got delayed. After that they said they didn't had any crew for the flight so they cancelled the flight till next day.

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

The flight crew on this leg of my trip was very friendly and pleasant. Every one of them was humorous, as well as helpful and accommodating. This group was BY FAR the best crew I’ve flown with. They deserve kudos.

Great. No choice for n/a. No food or entertainment options

No food is available without purchasing it and there is no in-flight entertainment. Both of these are OK because we got an inexpensive flight from Allegiant and, otherwise, our experience was excellent.

just had water and there was plenty of leg & seat room. But then i don't weight 220#s!!

Not totally their fault- screaming kids that had zero parent intervention.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

I had a fantastic experience with Allegiant. I had wheelchair assistance and they helped me find my luggage and brought me to my car. Even loaded my luggage. Wonderful service!! Thank you Allegiant!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

There is not one likable thing about this airline. It’s starts with the deceptive pricing and continues through the whole flight. The worst staff I’ve ever experienced way over priced bags absolutely no food or drink (unacceptable and you should be embarrassed) the seats are cramped and uncomfortable there is no entertainment there is nothing about this trash airline that constitutes any amount of money. It’s worse than spirit and way more expensive it is disgraceful. Do not travel with Allegiant I repeat do not bother no matter what they say the price is it is never ever going to be the right choice I’m mind blown at how awful the entire experience was I’m embarrassed that I chose so poorly I cannot reiterate enough how beyond horrible this company and its staff are, not one person on this flight or at the airport is qualified to sweep up trash on a city sidewalk they should certainly never be given any job that requires a brain or manners or communication with human beings, what a disgrace to the human race. Your criminal chiselers and should be put out to pasture

Great flight. Friendly staff. Free snacks and drinks would be nice. I would love fewer taxes and fees added on.

My 90 year old father flew with me. He needed wheel chair assistance and is nearly deaf. The staff was amazing with him.

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

This flight was delayed but it worked in my favor because my Atlanta to Dallas flight was delayed.

This was a hard flight. 3 delays out of OKC (1 on the Tarmac). Delay in Atlanta coming to Dallas. total travel time was the equivalent of driving from OKC to Atlanta.

Like: flights are on time, good boarding process Can improve: planes are old, improve entertainment and make space more comfortable

Had to wait for a gate for a long time, then waited on the run way for a long time before leaving. The actual flights part was good.

The airplane was an old model, the overhead didn’t have enough room for people’s items and made boarding and boarding disappointing and stressful. Crew allowed passengers to bring more than the permitted baggage sizes.

Flying in the United States with the major airlines has become so underwhelming. A 2-3hr flight in most other parts of the world with the major carriers of the area comes with newer, CLEANER aircraft and significantly better in flight service in terms of both staff attitude and a actual meal service.

On time departure and early arrival. Flight attendant very nice.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Altoona
Urbandale
Newton
Johnston
Osceola
Grinnell
Carlisle

Everything you need to know for your flight to Des Moines

Flights with popular airlines flying to Des Moines

Flights from the other most popular airlines that fly from the United States to Des Moines according to KAYAK users. Prices are the lowest found on KAYAK over the last 7 days. Price and availability are not guaranteed.