TYS - BRU

$459 Find Cheap Flights from Knoxville to Brussels Airport

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Bruxelles-National departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$459
British Airways
Wed 2/11Wed 2/18
TYS - BRU • 2 stops
Cheapest one-way
Multiple Airlines
Thu 11/27
TYS - BRU • multi-stop
Top airlines
British Airways
Cheapest • from $459 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Bruxelles-National!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Bruxelles-National (TYS-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Bruxelles-National that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Bruxelles-National

Wed, Feb 11 - Wed, Feb 18
British Airways Logo
5:15 pm - 7:35 pmTYS-BRU
20h 20m2 stops
British Airways Logo
8:30 pm - 9:23 pmBRU-TYS
30h 53m2 stops
$459British Airways
Find Deal
Wed, Feb 11 - Wed, Feb 18
Lufthansa Logo
2:25 pm - 7:15 amTYS-BRU
10h 50m1 stop
Lufthansa Logo
11:55 am - 7:29 pmBRU-TYS
13h 34m1 stop
$500Lufthansa
Find Deal
Wed, Feb 11 - Wed, Feb 18
Multiple Airlines Logo
2:25 pm - 7:15 amTYS-BRU
10h 50m1 stop
Multiple Airlines Logo
10:30 am - 7:29 pmBRU-TYS
14h 59m2 stops
$501Multiple Airlines
Find Deal
Wed, Feb 18 - Sun, Feb 22
United Airlines Logo
2:21 pm - 1:15 pmTYS-BRU
16h 54m2 stops
United Airlines Logo
10:10 am - 1:20 pmBRU-TYS
33h 10m1 stop
$503United Airlines
Find Deal
Wed, Feb 18 - Sun, Feb 22
Brussels Airlines Logo
2:21 pm - 7:15 amTYS-BRU
10h 54m1 stop
Brussels Airlines Logo
11:55 am - 7:29 pmBRU-TYS
13h 34m1 stop
$507Brussels Airlines
Find Deal
Wed, Feb 11 - Wed, Feb 18
Multiple Airlines Logo
9:30 am - 7:50 amTYS-BRU
16h 20m3 stops
Multiple Airlines Logo
10:00 am - 9:10 pmBRU-TYS
17h 10m2 stops
$513Multiple Airlines
Find Deal
Wed, Feb 18 - Sun, Feb 22
United Airlines Logo
10:55 am - 8:05 amTYS-BRU
15h 10m2 stops
United Airlines Logo
9:30 am - 9:10 pmBRU-TYS
17h 40m2 stops
$517United Airlines
Find Deal
Wed, Feb 11 - Wed, Feb 18
Air Canada Logo
9:30 am - 7:50 amTYS-BRU
16h 20m3 stops
Air Canada Logo
7:00 am - 7:29 pmBRU-TYS
18h 29m3 stops
$525Air Canada
Find Deal
Sat, Jan 10 - Sat, Jan 17
Multiple Airlines Logo
1:59 pm - 7:50 amTYS-BRU
35h 51m2 stops
Multiple Airlines Logo
5:30 pm - 7:27 pmBRU-TYS
55h 57m2 stops
$564Multiple Airlines
Find Deal
Sat, Jan 10 - Sat, Jan 17
Lufthansa Logo
7:20 pm - 7:15 amTYS-BRU
29h 55m1 stop
Lufthansa Logo
5:30 pm - 7:27 pmBRU-TYS
55h 57m2 stops
$579Lufthansa
Find Deal
Booking Insights

KAYAK's insights & trends for Knoxville to Bruxelles-National flights

Get data-powered insights and trends into flights from Knoxville to Bruxelles-National to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to Brussels Airport?

The average price of all round-trip flights from Knoxville to Brussels Bruxelles-National Airport clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Knoxville to Brussels Airport, look for departures on Tuesdays and avoid leaving on a Thursday, as it's usually the priciest day. When flying back from Brussels Airport, Saturday is the cheapest day to fly and Sunday is the most expensive.

Find deals

Good to know

Cheapest flight$459
Flight from Knoxville to Brussels Airport

When to book flights from Knoxville to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Knoxville to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Knoxville to Brussels Airport flights

  • What is the cheapest flight from Knoxville to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Knoxville to Brussels Bruxelles-National Airport was $459 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Brussels Airport?

    Yes, you’ll need a passport to travel to Brussels Airport from Knoxville.

  • Which airports will I be using when flying from Knoxville to Brussels Airport?

    On your way to Brussels Airport, you’ll fly out from Knoxville McGhee Tyson. You’ll be landing at Brussels Bruxelles-National.

  • Which aircraft models fly most regularly from Knoxville to Brussels Airport?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Brussels Airport?

    Star Alliance is the only airline alliance operating flights between Knoxville and Brussels Airport.

  • How does KAYAK find such low prices on flights from Knoxville to Brussels Airport?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Brussels Airport.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Brussels Airport?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels Airport from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Brussels Airport?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels Airport with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Brussels Airport?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels Airport from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Bruxelles-National

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Bruxelles-National? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9057 reviews
7.1Entertainment
8.1Crew
6.6Food
7.7Boarding
7.3Comfort
Airline reviews

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

6.0 GoodAnonymous, Nov 2025IAH - MEX
Read more United Airlines reviews

Seats had less pitch than a regional jet. Food was OK. Have to buy alcohol on US based carriers flying international. Boarding was a mess. Did not have bags but overhead space was gone quick. Would like to see the airlines enforce the one bag over and one bag under policy

Ot was overall fine. Left on time and had basic snacks. Weather was finicky but that’s not the airlines fault.

from SFO-> FRA flight, AVML meal was significantly less compared to regular meal, especially no Desert, no Bread, no sides.

Very nice flight love the small aircraft. We had a wonderful flight attendant. Nice to see someone that really enjoys her job. Don't have her name but had a southern accent.

This was an older airplane. The cabin was constantly warm to hot throughout the 10 hour flight and there were no vents to personalize air flow. Also since it was an older plane, the material and comfort of the chairs were very uncomfortable. I left my flight with major soreness on my tailbone.

Very thoughtful flight attendant offered me water immediately since I had run to make my connection.

Door to door, the crew and staff were amazing. It was a stressful travel day with delays, but they were focused on customers and doing what they could to get us to our destinations.

Even though we were delayed, we were able to make our connection

Seats in waiting area and on plane hard as rock. Fast internet on the flight was great! Crew was kind.

Starlink wifi on the Embraer E175 is an excellent experience. I was able to connect and work from IAD all the way to approach into BTV.

Everything you need to know for your flight from Knoxville to Bruxelles-National

Information on your arrival and departure airports

Knoxville (TYS)
Bruxelles-National (BRU)