TYS - BRU

$458 Find Cheap Flights from Knoxville to Brussels

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Bruxelles-National departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
Travelers love KAYAK
41 299 237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$458
Delta
Sun 3/22Thu 4/2
TYS - BRU • 1 stop
Cheapest one-way
Multiple Airlines
Fri 1/16
TYS - BRU • multi-stop
Top airlines
British Airways
Cheapest • from $458 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Bruxelles-National!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Bruxelles-National (TYS-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Bruxelles-National that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Bruxelles-National

Sun, Mar 22 - Thu, Apr 2
Delta Logo
12:03 pm - 8:00 am
TYS
-
BRU
14h 57m
1 stop
Delta Logo
9:45 am - 5:53 pm
BRU
-
TYS
14h 08m
1 stop
$458Delta
Wed, Jan 28 - Tue, Feb 3
American Airlines Logo
4:00 pm - 4:20 pm
TYS
-
BRU
18h 20m
2 stops
American Airlines Logo
7:00 am - 11:59 pm
BRU
-
TYS
22h 59m
2 stops
$472American Airlines
Wed, Apr 8 - Wed, Apr 22
KLM Logo
3:13 pm - 7:40 am
TYS
-
BRU
10h 27m
1 stop
KLM Logo
6:20 am - 4:49 pm
BRU
-
TYS
16h 29m
2 stops
$488KLM
Mon, Mar 23 - Tue, Mar 31
Delta Logo
3:13 pm - 8:00 am
TYS
-
BRU
11h 47m
1 stop
Delta Logo
3:10 pm - 4:43 pm
BRU
-
TYS
31h 33m
2 stops
$489Delta
Tue, Mar 24 - Tue, Mar 31
Delta Logo
11:18 am - 2:15 pm
TYS
-
BRU
21h 57m
2 stops
Delta Logo
9:45 am - 11:15 am
BRU
-
TYS
31h 30m
1 stop
$490Delta
Tue, Mar 24 - Tue, Mar 31
Air Canada Logo
9:40 am - 7:50 am
TYS
-
BRU
17h 10m
2 stops
Air Canada Logo
9:25 am - 11:03 pm
BRU
-
TYS
43h 38m
2 stops
$492Air Canada
Thu, Apr 9 - Mon, Apr 20
British Airways Logo
7:00 am - 8:40 pm
TYS
-
BRU
31h 40m
2 stops
British Airways Logo
3:05 pm - 9:57 pm
BRU
-
TYS
36h 52m
2 stops
$496British Airways
Wed, Jan 28 - Tue, Feb 3
Multiple Airlines Logo
9:30 am - 7:50 am
TYS
-
BRU
16h 20m
3 stops
Multiple Airlines Logo
10:00 am - 8:52 pm
BRU
-
TYS
40h 52m
2 stops
$500Multiple Airlines
Wed, Feb 25 - Sun, Mar 1
United Airlines Logo
2:21 pm - 1:15 pm
TYS
-
BRU
16h 54m
2 stops
United Airlines Logo
11:55 am - 3:15 pm
BRU
-
TYS
33h 20m
1 stop
$505United Airlines
Wed, Apr 8 - Wed, Apr 22
Lufthansa Logo
1:53 pm - 9:00 am
TYS
-
BRU
13h 07m
1 stop
Lufthansa Logo
10:15 am - 11:03 pm
BRU
-
TYS
18h 48m
1 stop
$507Lufthansa
Booking Insights

KAYAK's insights & trends for Knoxville to Bruxelles-National flights

Get data-powered insights and trends into flights from Knoxville to Bruxelles-National to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Brussels were found on British Airways ($458) and Delta ($458).

Find deals

Good to know

Cheapest flight$458
Flight from Knoxville to Brussels

When to book flights from Knoxville to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Knoxville to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Knoxville to Brussels flights

  • What is the cheapest flight from Knoxville to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Knoxville to Brussels Bruxelles-National Airport was $458 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Brussels?

    Yes, you’ll need a passport to travel to Brussels from Knoxville.

  • Which airports will I be using when flying from Knoxville to Brussels?

    On your way to Brussels, you’ll fly out from Knoxville McGhee Tyson. You’ll be landing at Brussels Bruxelles-National.

  • Which aircraft models fly most regularly from Knoxville to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Brussels?

    Star Alliance is the only airline alliance operating flights between Knoxville and Brussels.

  • How does KAYAK find such low prices on flights from Knoxville to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Bruxelles-National

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Bruxelles-National? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9163 reviews
7.1Entertainment
8.1Crew
7.3Comfort
6.6Food
7.7Boarding
Airline reviews

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

10.0 ExcellentDavid, Jan 2026
IAD - BNA
Read more United Airlines reviews

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Ineffective communication with United resulted in lost baggage. Their Baggage Tracing counter at MUC was shut down from 11:00-14:15 on my arrival. Undertrained, underinformed staff had me Running all over MUC to find someone to help me to no avail. Staff was rude, unhelpful, and unable to effectively use the systems they did have operational. They refused to contact United in any way or provide any accommodation or other resources while I waited for my luggage. This has destroyed my downstream itinerary. If they had even the slightest visibility I may have been able to reschedule/plan, but again, their staff provided nothing, and did nothing more than their website, which doesn’t even work on a standard phone browser. Miserable failure at all levels that weren’t associated with the operation of the aircraft.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

Everything you need to know for your flight from Knoxville to Bruxelles-National

Information on your arrival and departure airports

Knoxville (TYS)
Bruxelles-National (BRU)