TYS - BRU

$602 Find Cheap Flights from Knoxville to Brussels

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Bruxelles-National departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$602
United Airlines
Wed 4/8Wed 4/22
TYS - BRU • 2 stops
Top airlines
United Airlines
Cheapest • from $602 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Bruxelles-National. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Washington, D.C. (IAD)
Cheapest • Avg $1,267 (round-trip)
Washington, D.C. (IAD)
Shortest trip • 10h 58m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Bruxelles-National!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Bruxelles-National (TYS-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Bruxelles-National that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Bruxelles-National

Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
1:52 pm - 8:00 pm
TYS
-
BRU
24h 08m
2 stops
United Airlines Logo
9:55 am - 10:34 pm
BRU
-
TYS
42h 39m
2 stops
$602United Airlines
Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
9:40 am - 7:15 am
TYS
-
BRU
15h 35m
1 stop
United Airlines Logo
9:55 am - 10:34 pm
BRU
-
TYS
42h 39m
2 stops
$605United Airlines
Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
7:00 am - 7:10 am
TYS
-
BRU
18h 10m
2 stops
United Airlines Logo
9:55 am - 10:34 pm
BRU
-
TYS
42h 39m
2 stops
$609United Airlines
Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
2:25 pm - 7:15 am
TYS
-
BRU
10h 50m
1 stop
United Airlines Logo
10:15 am - 11:08 pm
BRU
-
TYS
18h 53m
1 stop
$625United Airlines
Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
1:52 pm - 8:00 pm
TYS
-
BRU
24h 08m
2 stops
United Airlines Logo
7:00 am - 10:50 am
BRU
-
TYS
33h 50m
2 stops
$635United Airlines
Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
1:52 pm - 8:00 pm
TYS
-
BRU
24h 08m
2 stops
United Airlines Logo
10:15 am - 11:08 pm
BRU
-
TYS
18h 53m
1 stop
$647United Airlines
Mon, Apr 13 - Mon, Apr 20
United Airlines Logo
7:20 pm - 8:00 pm
TYS
-
BRU
18h 40m
2 stops
United Airlines Logo
12:00 pm - 7:42 pm
BRU
-
TYS
13h 42m
1 stop
$662United Airlines
Wed, Apr 8 - Wed, Apr 22
United Airlines Logo
10:49 am - 9:00 am
TYS
-
BRU
16h 11m
1 stop
United Airlines Logo
10:15 am - 11:08 pm
BRU
-
TYS
18h 53m
1 stop
$675United Airlines
Fri, Apr 24 - Sat, May 2
United Airlines Logo
1:52 pm - 1:15 pm
TYS
-
BRU
17h 23m
2 stops
United Airlines Logo
10:15 am - 4:54 pm
BRU
-
TYS
12h 39m
1 stop
$722United Airlines
Fri, Apr 24 - Sat, May 2
United Airlines Logo
9:40 am - 7:15 am
TYS
-
BRU
15h 35m
1 stop
United Airlines Logo
10:15 am - 4:54 pm
BRU
-
TYS
12h 39m
1 stop
$725United Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Bruxelles-National flights

Get data-powered insights and trends into flights from Knoxville to Bruxelles-National to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Knoxville to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Knoxville to Brussels were found on United Airlines ($602) and Lufthansa ($975).

Good to know

Cheapest flight$602
Flight from Knoxville to Brussels

When to book flights from Knoxville to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Knoxville to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Knoxville to Brussels flights

  • What is the cheapest flight from Knoxville to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Knoxville to Brussels Bruxelles-National Airport was $602 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Brussels?

    Yes, you’ll need a passport to travel to Brussels from Knoxville.

  • Which airports will I be using when flying from Knoxville to Brussels?

    On your way to Brussels, you’ll fly out from Knoxville McGhee Tyson. You’ll be landing at Brussels Bruxelles-National.

  • Which aircraft models fly most regularly from Knoxville to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Brussels?

    Star Alliance is the only airline alliance operating flights between Knoxville and Brussels.

  • How does KAYAK find such low prices on flights from Knoxville to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Bruxelles-National

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Bruxelles-National? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9382 reviews
7.1Entertainment
8.1Crew
7.7Boarding
6.6Food
7.3Comfort
Airline reviews

It’s always a great time flying with united airlines.

10.0 ExcellentCollins, Mar 2026
BOS - DEN
Read more United Airlines reviews

It’s always a great time flying with united airlines.

Good flight. Efficient boarding and competent flight crew. No problems until we arrived at our destination gate. We were early so there was an aircraft at the gate that had to move before we could pull in. Then, due to the type of aircraft we flew, the cabin door could not be opened until some luggage from the cargo bay was offloaded to preserve center of gravity characteristics. So, that further delayed deplaning. Despite being 20 minutes early on landing, we ended up being 5 to 10 minutes late after all the delays.

Everything went well except the turbulence what no one have a control of but pilot and crew handled very good!

There was no WiFi available, there were mechanical problems with the plane and we landed at C 124, then the gate was switched to A 26, then all the way back to C126! For a 75 yo woman traveling alone, this was a difficult journey, indeed!

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Complimentary light meal would be appreciated. But great flight crew service on all legs

Terrible because it was cancelled due to volcanic ash clouds in Guatemala while all other airlines kept flying. Had to pay for a hotel to stay overnight in Houston and try to fly next day.

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We got delayed three hours and nobody thought to have the bathroom fixed while we were sitting waiting to board? took a full hour to have maintenance come and check it off. Had to shut the bathroom down twice so that the pilots could go to the bathroom. Everyone missed their connections.

Everything you need to know for your flight from Knoxville to Bruxelles-National

Information on your arrival and departure airports