TYS - BRU

$922 Find Cheap Flights from Knoxville to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Bruxelles-National departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$922
United Airlines
Tue 9/1Wed 9/9
TYS - BRU • 2 stops
Cheapest one-way
$604
Multiple Airlines
Thu 6/25
TYS - BRU • 2 stops
Top airlines
Cheapest • from $922 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Knoxville and Bruxelles-National. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $1,492 (round-trip)
Shortest trip • 11h 08m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Bruxelles-National!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Knoxville to Bruxelles-National (TYS-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Bruxelles-National that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Bruxelles-National

Tue, Sep 1 - Wed, Sep 9
United Airlines Logo
3:25 pm - 8:00 pm
TYS
-
BRU
22h 35m
2 stops
United Airlines Logo
12:00 pm - 11:57 pm
BRU
-
TYS
17h 57m
1 stop
$922United Airlines
Tue, Sep 1 - Wed, Sep 9
United Airlines Logo
10:00 am - 7:15 am
TYS
-
BRU
15h 15m
1 stop
United Airlines Logo
10:15 am - 4:59 pm
BRU
-
TYS
12h 44m
1 stop
$925United Airlines
Wed, May 13 - Tue, May 19
Delta Logo
1:59 pm - 7:40 am
TYS
-
BRU
11h 41m
1 stop
Delta Logo
9:45 am - 8:28 pm
BRU
-
TYS
16h 43m
1 stop
$1,030Delta
Wed, May 13 - Tue, May 19
United Airlines Logo
1:52 pm - 9:00 am
TYS
-
BRU
13h 08m
1 stop
United Airlines Logo
9:55 am - 8:12 pm
BRU
-
TYS
16h 17m
2 stops
$1,034United Airlines
Wed, May 13 - Tue, May 19
United Airlines Logo
7:00 am - 7:15 am
TYS
-
BRU
18h 15m
2 stops
United Airlines Logo
11:10 am - 8:45 pm
BRU
-
TYS
15h 35m
2 stops
$1,035United Airlines
Wed, May 13 - Sun, May 17
United Airlines Logo
10:49 am - 9:00 am
TYS
-
BRU
16h 11m
1 stop
United Airlines Logo
10:15 am - 8:45 pm
BRU
-
TYS
16h 30m
1 stop
$1,090United Airlines
Wed, May 13 - Sun, May 17
United Airlines Logo
9:50 am - 7:15 am
TYS
-
BRU
15h 25m
1 stop
United Airlines Logo
11:10 am - 8:45 pm
BRU
-
TYS
15h 35m
2 stops
$1,095United Airlines
Mon, May 18 - Tue, May 26
British Airways Logo
5:57 pm - 7:10 pm
TYS
-
BRU
19h 13m
2 stops
British Airways Logo
7:55 pm - 5:45 pm
BRU
-
TYS
27h 50m
2 stops
$1,137British Airways
Thu, May 14 - Tue, May 19
United Airlines Logo
1:52 pm - 1:15 pm
TYS
-
BRU
17h 23m
2 stops
United Airlines Logo
10:15 am - 5:08 pm
BRU
-
TYS
12h 53m
1 stop
$1,142United Airlines
Thu, May 14 - Tue, May 19
Delta Logo
5:59 pm - 7:40 am
TYS
-
BRU
31h 41m
1 stop
Delta Logo
9:45 am - 11:56 pm
BRU
-
TYS
20h 11m
1 stop
$1,151Delta
Booking Insights

KAYAK's insights & trends for Knoxville to Bruxelles-National flights

Get data-powered insights and trends into flights from Knoxville to Bruxelles-National to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Knoxville to Brussels Bruxelles-National Airport?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Knoxville to Brussels Bruxelles-National Airport departing in September.

Good to know

Low seasonOctober
Cheapest flight$604
Best time to beat the crowds with an average 31% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Knoxville to Brussels

When to book flights from Knoxville to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Knoxville to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Knoxville to Brussels flights

  • What is the cheapest flight from Knoxville to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Knoxville to Brussels Bruxelles-National Airport was $604 for a one-way ticket and $922 for a round-trip.

  • Do I need a passport to fly between Knoxville and Brussels?

    Yes, you’ll need a passport to travel to Brussels from Knoxville.

  • Which airports will I be using when flying from Knoxville to Brussels?

    On your way to Brussels, you’ll fly out from Knoxville McGhee Tyson. You’ll be landing at Brussels Bruxelles-National.

  • Which aircraft models fly most regularly from Knoxville to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Brussels?

    Star Alliance is the only airline alliance operating flights between Knoxville and Brussels.

  • How does KAYAK find such low prices on flights from Knoxville to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Bruxelles-National

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Bruxelles-National? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9637 reviews
7.7Boarding
7.3Comfort
8.1Crew
7.1Entertainment
6.6Food
Airline reviews

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

8.0 ExcellentSally, Apr 2026
ORD - SNA
Read more United Airlines reviews

The crew was great. Very friendly and responsive. The plane was old, small and tight. We ran out of overhead space and I had to check. Middle seat was particularly tight.

Flight itself excellent, but delayed so missed connection & got to destination 2 hrs later

The flight crew on this leg of my trip was very friendly and pleasant. Every one of them was humorous, as well as helpful and accommodating. This group was BY FAR the best crew I’ve flown with. They deserve kudos.

boarded early to only find out that flight would sit at gate for 45 min to an hour. Landed in chicago and sat on runway for over an hour before got to gate. Total delay was extensive for a 45 min flight door to door.

The flight was delayed from take off because only one runway was operational in San Francisco.

Several missed and almost missed connections. It felt like everything was being patched together last minute without enough resources and it ended up being an extremely stressful experience that basically ruined our weekend on the west coast. What a waste.

Really hard landing... as in slammed into the runway then hit the brakes really hard ...

The flight was significantly delayed. The inbound flight from EWR was delayed departing because of mechanical problems. My original departure from CLT was 5:28 pm but due to the delay of the inbound flight, after arrival, deplaning, cleaning, boarding, we did not push back from the gate until 9:00 pm. Once in the air, the flight was smooth and what was originally supposed to be an arrival in ORD at 7:30 pm local time turned out to be 9:35 pm.

Putting people that close to the bathroom, where you have to look into the bathroom as people are exiting and entering was not great and the smell was also not great. I know the airlines are desperate for more chairs, but that seat is a crime.

My bags were misplaced!!! Im in a foreign country with no bags

Everything you need to know for your flight from Knoxville to Bruxelles-National

Information on your arrival and departure airports