TYS - BRU

$553 Find Cheap Flights from Knoxville to Brussels

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Bruxelles-National departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Knoxville to Brussels, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Knoxville to Brussels (TYS-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Bruxelles-National

Sat, Nov 29 - Sat, Dec 6
United Airlines Logo
6:45 am - 1:15 pmTYS-BRU
24h 30m2 stops
United Airlines Logo
10:00 am - 10:13 amBRU-TYS
30h 13m2 stops
$553United Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
United Airlines Logo
5:45 am - 7:15 amTYS-BRU
19h 30m1 stop
United Airlines Logo
10:00 am - 10:13 amBRU-TYS
30h 13m2 stops
$556United Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
United Airlines Logo
5:45 am - 7:15 amTYS-BRU
19h 30m1 stop
United Airlines Logo
11:55 am - 2:43 pmBRU-TYS
32h 48m1 stop
$562United Airlines
Find Deal
Fri, Mar 27 - Tue, Mar 31
United Airlines Logo
9:40 am - 7:15 amTYS-BRU
16h 35m1 stop
United Airlines Logo
12:00 pm - 11:59 pmBRU-TYS
17h 59m1 stop
$656United Airlines
Find Deal
Fri, Mar 27 - Tue, Mar 31
Delta Logo
4:00 pm - 8:00 amTYS-BRU
11h 00m1 stop
Delta Logo
10:25 am - 9:32 pmBRU-TYS
17h 07m2 stops
$666Delta
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Tue, Nov 4 - Mon, Nov 10
Air Canada Logo
7:20 pm - 7:50 amTYS-BRU
30h 30m2 stops
Air Canada Logo
10:00 am - 8:20 pmBRU-TYS
40h 20m2 stops
$714Air Canada
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Tue, Nov 4 - Mon, Nov 10
Multiple Airlines Logo
9:50 am - 7:50 amTYS-BRU
16h 00m3 stops
Multiple Airlines Logo
10:00 am - 10:55 pmBRU-TYS
18h 55m2 stops
$825Multiple Airlines
Find Deal
Fri, Mar 27 - Tue, Mar 31
American Airlines Logo
4:16 pm - 1:40 pmTYS-BRU
16h 24m2 stops
American Airlines Logo
10:55 am - 8:39 pmBRU-TYS
15h 44m2 stops
$872American Airlines
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Sat, Nov 29 - Sat, Dec 6
Multiple Airlines Logo
5:45 am - 7:50 amTYS-BRU
20h 05m3 stops
Multiple Airlines Logo
10:00 am - 10:48 amBRU-TYS
30h 48m2 stops
$1,008Multiple Airlines
Find Deal
Sat, Nov 29 - Sat, Dec 6
Air Canada Logo
5:45 am - 7:50 amTYS-BRU
20h 05m3 stops
Air Canada Logo
7:00 am - 7:29 pmBRU-TYS
18h 29m3 stops
$1,583Air Canada
Find Deal

Everything you should know

Top airlines
United Airlines
Cheapest • from $553 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$553
United Airlines
Sat 11/29Sat 12/6
TYS - BRU • 2 stops
Cheapest one-way
Multiple Airlines
Fri 10/17
TYS - BRU • multi-stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Bruxelles-National!
Booking Insights

KAYAK's insights & trends for Knoxville to Bruxelles-National flights

Get data-powered insights and trends into flights from Knoxville to Bruxelles-National to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Knoxville to Brussels?

The average price of all round-trip flights from Knoxville to Brussels Bruxelles-National Airport clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Knoxville to Brussels, look for departures on Tuesdays and avoid leaving on a Thursday, as it's usually the priciest day. When flying back from Brussels, Saturday is the cheapest day to fly and Sunday is the most expensive.

Good to know

Cheapest flight$553
Flight from Knoxville to Brussels

When to book flights from Knoxville to Bruxelles-National

Are your dates flexible? Find out the best times to travel from Knoxville to Bruxelles-National based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Knoxville to Brussels flights

  • What is the cheapest flight from Knoxville to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Knoxville to Brussels Bruxelles-National Airport was $553 for a round-trip ticket.

  • Do I need a passport to fly between Knoxville and Brussels?

    Yes, you’ll need a passport to travel to Brussels from Knoxville.

  • Which airports will I be using when flying from Knoxville to Brussels?

    On your way to Brussels, you’ll fly out from Knoxville McGhee Tyson. You’ll be landing at Brussels Bruxelles-National.

  • Which aircraft models fly most regularly from Knoxville to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Knoxville to Brussels?

    Star Alliance is the only airline alliance operating flights between Knoxville and Brussels.

  • How does KAYAK find such low prices on flights from Knoxville to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to Knoxville with another airline. Booking your flights between Knoxville and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Knoxville to Bruxelles-National

 
See real verified KAYAK customer reviews for airlines flying from Knoxville to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Knoxville to Bruxelles-National? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8982 reviews
7.3Comfort
6.6Food
8.1Crew
7.1Entertainment
7.7Boarding
Airline reviews

My husband and I recently had an unfortunate experience with Lufthansa. At the Philadelphia International airport, the ground staff refused to board us because we didn’t have a current visa stamped on our passports for Frankfurt. We completely understand that this was our mistake. we should have double-checked the visa requirements before our trip. However, the issue that upset us most was how the situation was handled by the staff. They told us they would mark it as “boarding denied due to visa issue”, but instead they recorded it as “no show”. Because of that incorrect entry, our return flight was automatically cancelled as well, which caused additional stress and expense. Mistakes can happen, but we expected more transparency and accuracy from a reputed airline like Lufthansa. It would have made a big difference if the staff had been more careful and considerate in documenting the situation correctly.

2.0 MediocreAnonymous, Oct 2025PHL - FRA
Read more United Airlines reviews

My husband and I recently had an unfortunate experience with Lufthansa. At the Philadelphia International airport, the ground staff refused to board us because we didn’t have a current visa stamped on our passports for Frankfurt. We completely understand that this was our mistake. we should have double-checked the visa requirements before our trip. However, the issue that upset us most was how the situation was handled by the staff. They told us they would mark it as “boarding denied due to visa issue”, but instead they recorded it as “no show”. Because of that incorrect entry, our return flight was automatically cancelled as well, which caused additional stress and expense. Mistakes can happen, but we expected more transparency and accuracy from a reputed airline like Lufthansa. It would have made a big difference if the staff had been more careful and considerate in documenting the situation correctly.

Flight was good but there are way to many announcements for credit cards etc.

During booking, I kept trying submitting my payment from the Mexican website and it didn't work. After I had the idea to change it to the Canadian website, it worked but I had to be charged the equivalent of 50 CAD more. I received the clear instruction that I would only be able to check-in at the airport and that it was impossible to select a seat 24 hours before departure, that I had to pay 144 CAD to do so, although not only was I able to check-in 24 hours before departure, but I could have selected my seats for free then. All in all, I almost threw $200 out the window due to misleading information. Besides, the app kept crashing, the information to get to the gate on the app was inaccurate, my gate was switched and I was only informed once in the air (luckily I had noticed the departure pannel), I was not addressed in my language beforehand and even if I tried I was immediately answered in English (which meant the crew understood but didn't want to answer accordingly), there was only one snack & beverage service on my medium haul flight and no beverage service on my short haul flight. To be fair, the planes were comfortable, the crew apart from the language issue was helpful, dynamic and engaging, the plane was clean and the directions were clear and direct. United has a lot of potential to be one of my favourite airlines, but the devil is in the details and a lot of them missed the target.

Flight was timely, relatively comfortable, with decent entertainment and food served. Only problem encountered was with the free messaging which I highly appreciate, but it did not work from iphone to non-iphones.

Better WiFi. I cannot understand that in 2025, United is so behind on a technology that is now a necessity and still painfully unreliable, slow and keeps disconnecting.

The entertainment available didn’t work for anyone on the flight. Long 6 hr flight with no entertainment option and the staff didn’t know until an hour into the flight when we made sure they knew about it. They had no way to fix it.

Crew seemed a bit cranky. No seatback screens. But boarding was efficient and on time and we arrived early.

The worst landing I have ever had on a domestic flight. Thought we would lose the landing gear on landing in Newark. Then we spent 40 minutes trying to position the plane in the right place to be able to get the jet way to the plane. The plane arrived stopped. The announcer was that we were there. Everybody got up, then we were told to sit back down because they had to have us towed to a different position. We got towed and then everyone stood up and they told us we were in the wrong position to sit back down again, and then we got towed to a different position This did not happen immediately. It was 30 minutes while we wandered around a small section of the tarmac in Newark close to the gate, but apparently not close enough. Horrifying experience The CAB should be investigating that flight

Food was poorly timed and not good.. Hand held snacks, really. I kept asking for water and never got any. Service was rushed for a 7-hour flight.

Boarding was organized. Old plane. Seat fairly comfortable. Business Class much too large so you don’t receive as much attention as you should considering what you pay for the seat.

Everything you need to know for your flight from Knoxville to Bruxelles-National

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