TYS - RSW

$130 Find Cheap Flights from Knoxville to Fort Myers - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$206
Typical prices: $318-$565
Multiple Airlines
Thu 1/25Sun 1/28
TYS - RSW • 1 stop
Cheapest one-way
$130
Typical prices: $175-$351
American Airlines
Mon 12/31
TYS - RSW • 1 stop
Nonstop flights
There are currently no direct flights between Knoxville and Fort Myers. You'll need to take a connecting flight to reach the destination.
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Insights
When to travel
Cheapest • 32% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $398 (round-trip)
Shortest trip • 4h 15m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Knoxville to Fort Myers (TYS-RSW)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Fort Myers

Mon, Jan 25 - Thu, Jan 28
Multiple Airlines Logo
9:00 am - 8:05 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
11h 05m1 stop Philadelphia
Multiple Airlines Logo
9:00 pm - 1:44 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
16h 44m1 stop Philadelphia
$206Multiple Airlines
Tue, Dec 1 - Wed, Dec 9
American Airlines Logo
5:01 pm - 11:17 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
6h 16m1 stop Charlotte Douglas
American Airlines Logo
4:47 pm - 8:43 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
3h 56m1 stop Charlotte Douglas
$259American Airlines
Wed, Dec 2 - Wed, Dec 9
American Airlines Logo
5:17 pm - 9:55 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
4h 38m1 stop Charlotte Douglas
American Airlines Logo
7:49 am - 11:51 amRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
4h 02m1 stop Charlotte Douglas
$259American Airlines
Thu, Dec 17 - Tue, Dec 22
American Airlines Logo
8:01 pm - 12:38 amTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
4h 37m1 stop Charlotte Douglas
American Airlines Logo
7:31 pm - 11:53 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
4h 22m1 stop Charlotte Douglas
$259American Airlines
Sat, Jan 23 - Sat, Jan 30
Southwest Logo
2:25 pm - 8:40 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
6h 15m2 stops Nashville Intl Orlando
Southwest Logo
8:00 am - 12:00 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
4h 00m1 stop Nashville Intl
$264Southwest
Sat, Jan 23 - Sat, Jan 30
Southwest Logo
6:45 am - 3:55 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
9h 10m2 stops Nashville Intl Chicago Midway
Southwest Logo
8:00 am - 7:45 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
11h 45m2 stops Nashville Intl Baltimore/Washington
$269Southwest
Mon, Jan 25 - Thu, Jan 28
Multiple Airlines Logo
9:00 am - 8:05 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
11h 05m1 stop Philadelphia
Multiple Airlines Logo
12:36 pm - 6:28 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
29h 52m2 stops Detroit Metropolitan Wayne County Orlando
$271Multiple Airlines
Tue, Mar 16 - Fri, Mar 19
Delta Logo
7:07 am - 12:01 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
4h 54m1 stop Atlanta Hartsfield-Jackson
Delta Logo
4:30 pm - 9:45 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
5h 15m1 stop Atlanta Hartsfield-Jackson
$363Delta
Thu, Mar 25 - Wed, Mar 31
Delta Logo
8:47 am - 1:53 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
5h 06m1 stop Atlanta Hartsfield-Jackson
Delta Logo
8:10 am - 1:28 pmRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
5h 18m1 stop Atlanta Hartsfield-Jackson
$363Delta
Sun, Apr 4 - Wed, Apr 7
Delta Logo
5:05 pm - 9:17 pmTYS  Knoxville McGhee Tyson-RSW Fort Myers SW Florida Intl
4h 12m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:35 am - 11:06 amRSW  Fort Myers SW Florida Intl-TYS Knoxville McGhee Tyson
5h 31m1 stop Atlanta Hartsfield-Jackson
$363Delta
Booking Insights

Price, demand and travel trends for Knoxville to Fort Myers flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

What's the cheapest day of the week to fly from Knoxville to Fort Myers?

Based on deals KAYAK users found in the last 12 months, Tuesday is the cheapest day of the week to fly from Knoxville to Fort Myers. It’s 10% cheaper than the average day, while Sunday is the most expensive, with prices 36% higher.

What’s the cheapest month to fly from Knoxville to Fort Myers?

•June is the cheapest month to fly from Knoxville to Fort Myers at $267 round-trip.
•September ($590) and March ($568) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 120% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Key details for Knoxville to Fort Myers flights

Low season

August

Cheapest flight

$130
Beat the crowds with an average 52% drop in travelers.
The most popular month to fly with an average 100% increase in travelers.
One-way flight from Knoxville to Fort Myers

When to book flights from Knoxville to Fort Myers

Are your dates flexible? Find out the best times to travel from Knoxville to Fort Myers based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Knoxville to Fort Myers flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Knoxville to Fort Myers?

    Only Economy Class is available on flights from Knoxville to Fort Myers.

  • How long is a flight from Knoxville to Fort Myers?

    A nonstop flight from Knoxville to Fort Myers takes 00m, covering 653 miles.

  • Do I need a passport to fly from Knoxville to Fort Myers?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Knoxville to Fort Myers flight?

    Round-trip flights from Knoxville to Fort Myers range from $318 to $565, with an average of $392 over the past 12 months. Anything below $318 counts as a good deal.

  • Have flight prices from Knoxville to Fort Myers changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $206 to $1,701. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from Knoxville to Fort Myers looking right now?

    One-way fares from Knoxville to Fort Myers are currently lower than usual. Average one-way flight prices are about $250, which is 11% below the typical average for this route.

  • What car rental options are available at Fort Myers SW Florida Intl Airport (RSW)?

    Fort Myers SW Florida Intl Airport (RSW) hosts 5 major car rental companies, with daily rates averaging $48 for economy cars. Top options include:

    • Hertz
    • Dollar
    • Thrifty
    • Europcar
    • Fox

  • Which airports can I use when flying from Knoxville to Fort Myers?

    Flights from Knoxville to Fort Myers usually depart from Knoxville McGhee Tyson (TYS) and arrive at Fort Myers SW Florida Intl (RSW).

  • Which airports do connecting flights from Knoxville to Fort Myers pass through?

    One-stop flights from Knoxville to Fort Myers most commonly connect through:

    • Charlotte Douglas (CLT) - 52% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 43% of one-stop connections
    • Nashville Intl (BNA) - 2% of one-stop connections
    • Baltimore/Washington (BWI) - 2% of one-stop connections

  • Can I save money by using flexible dates for flights from Knoxville to Fort Myers?

    Yes. Flexible dates can save you up to 34% on flights from Knoxville to Fort Myers. Tuesday is the cheapest departure day at $356 round-trip on average, while Sunday is the most expensive at $536, a difference of $180.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Knoxville to Fort Myers?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 4h 15m, compared with 4h 41m via Charlotte Douglas (CLT) and 5h 22m via Nashville Intl (BNA).

  • What popular places can I visit in Fort Myers?

    Some of the most popular sights in Fort Myers are Lee Memorial Hospital, Terry Park Ballfield and Red Sox Stadium. These are among the most viewed places in Fort Myers on KAYAK.

Your guide to booking Knoxville to Fort Myers flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Tuesday departure and avoid flying on Sunday. On this route, Tuesday flights average $356, about $180 less than Sunday fares (34% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Knoxville to Fort Myers trip for June. Fares historically average $267 round-trip in that month - typically $323 less than the most expensive month, which is September (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Fort Myers SW Florida Intl Airport.

    • Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
    • Holiday Inn Express & Suites Fort Myers Airport By IHG

More options for your flight from Knoxville to Fort Myers

Complete your trip to Fort Myers with a hotel stay or car rental